This application claims the benefit of German Patent Application No. 102020134181.4, filed Dec. 18, 2020, which is hereby incorporated herein by reference in its entirety.
The present invention relates to a device for administering a fluid, which device can be designed, for example, as a needle-free self-filling syringe with which a liquid medicament, a liquid pharmaceutical product, a liquid vaccine or the like can be administered to animals (in particular by intramuscular administration).
A device for administering a fluid, such as mentioned above, should be as light as possible, and thus able to be carried with one hand for a long period of time by a user, and at the same time should permit the desired injection (in particular the needle-free intramuscular injection).
It is an object herein to provide a device for administering a fluid.
A device for administering a fluid has a first sealing element, which is designed as a single-acting sealing element, and a second sealing element, which is spaced apart from the first sealing element, and is designed as a single-acting or double-acting sealing element. Thus, it is possible to provide a good seal of the rear end of the cylinder both with respect to high, dynamic pressures and also to negative pressure. Thus, the first sealing element provides sealing of the rear end of the cylinder with respect to positive pressure, which occurs when the fluid is being administered. Moreover, the provision of the second sealing element has the effect that the rear end of the cylinder is sealed off with respect to negative pressure in the cylinder, which occurs when new fluid is being sucked in for the next administering procedure.
It can thus be said that a tandem seal is provided which is optimized to seal off the rear end of the cylinder to positive pressure (by means of the first sealing element) and to seal off the rear end of the cylinder to negative pressure (by means of the second sealing element).
Here, a single-acting first sealing element is understood in particular as a sealing element which seals off the rear end of the cylinder to positive pressure in the cylinder and which does not seal off the rear end of the cylinder to negative pressure in the cylinder (and thus positive pressure outside at the rear end of the cylinder). Thus, only the positive pressure in the cylinder is sealed off with respect to the rear end.
A single-acting second sealing element is understood in particular as a sealing element which seals off the rear end of the cylinder to negative pressure in the cylinder (and thus to positive pressure outside the cylinder at the rear end). Here, a double-acting second sealing element (or a dual-acting second sealing element) is in particular a sealing element which seals off the rear end of the cylinder with respect to positive pressure and negative pressure in the cylinder.
The first sealing element can have in particular a U-shaped or V-shaped cross section, wherein the opening of the U-shaped or V-shaped cross section points in the direction of the open dispensing end.
The first sealing element can moreover have a tensioning means (e.g. a spring), which presses the two limbs of the U-shaped or V-shaped cross section radially apart from each other.
The material used for the first sealing element can be plastic, a polymer, a fluoropolymer, a polyurethane (e.g. an injection moulded polyurethane or casted polyurethane), an elastomer or PTFE (polytetrafluoroethylene). These materials can contain fillers (e.g. carbon fibres or glass fibres) and/or additives in order to adjust the desired properties of the sealing element. Thus, the first sealing element can be produced from PTFE or a PTFE compound. A PTFE compound is understood in particular as a mixture of PTFE with at least one further substance (e.g. carbon, carbon fibres, carbon black, glass fibres, organic fillers, metals, metal alloys, etc.). If a spring is provided, the latter is preferably made of metal.
The first sealing element can have a ring-shaped sealing part, and a spring element which subjects the ring-shaped sealing part to radially inwardly directed tensioning.
Thus, the ring-shaped sealing part, in the installed state, can be subjected to radially inwardly directed pretensioning.
The ring-shaped sealing part can be produced from a thermoplastic, and the spring element can be produced from an elastomer. The spring element can be designed in particular as an O-ring.
The second sealing element can be designed in the same way as the first sealing element. It is then arranged at 180° relative to the first sealing element (the opening of the U-shaped or V-shaped cross section points away from the open dispensing end and thus points towards the rear end of the cylinder) in order to ensure the desired sealing of the rear end of the cylinder with respect to negative pressure in the cylinder.
It is moreover possible that the second sealing element is designed as a double-acting sealing element. In this case, it can be designed as an O-ring for example.
The same materials as were used for the first sealing element can be used for the second sealing element. For example, elastomers (e.g. fluoroelastomer), PTFE or PTFE compounds can preferably be used.
The first and the second sealing element can be arranged or provided on the cylinder, such that the piston moves relative to the sealing elements. In such an arrangement, the sealing elements are often designated as rod seals.
Alternatively, it is possible that the first and the second sealing element are secured on the piston, such that the piston moves together with the sealing elements in the cylinder. In such an arrangement, the sealing elements are often designated as piston seals.
It is moreover possible to provide a lubricating ring which is spaced apart from the second sealing element along the first direction. The lubricating ring can, for example, be designed as a felt ring or be formed from a sponge-like material. Moreover, the lubricating ring can have oil or grease applied to it. This ensures good lubrication of the piston during the movement in the cylinder.
The cylinder can be designed in one part or in multiple parts and in particular in two parts. In this case, the cylinder can comprise a rear cylinder part, of which the rear end forms the rear end of the cylinder. The first sealing element and second sealing element can be arranged in the rear cylinder part. Moreover, if a lubricating ring is provided, the latter can likewise be arranged in the rear cylinder part.
The rear cylinder part can be connected to a further part of the cylinder (for example the front cylinder part). The connection can be, for example, a releasable connection. For example, it can be provided in particular as a snap-fit closure or screw connection.
The movement of the piston in the cylinder can be effected manually or can be motorized. A motor can be provided which executes both the movement of the piston away from the open dispensing end and also the movement towards the open dispensing end. Alternatively, the motor can effect only the movement of the piston away from the open dispensing end, in which case a tensioning unit (e.g. one or more springs) of a tensioning device is tensioned. For the administering procedure, the tensioning unit is freed, such that the tensioning energy is converted into a movement of the piston towards the open dispensing end. In this way, a high pressure can be built up, which is desired in particular for needle-free administration of the fluid.
The tensioning device can have a ramp which is rotatable by means of a motor and which has a ramp track extending along a helical line, wherein the ramp track ascends from a first plateau along a region of inclination to a second plateau and descends from the second plateau to the first plateau via a transition flank, wherein the ramp track has a transfer region connecting the second plateau and the transition flank. The tensioning device can moreover comprise a roller which is in contact with the ramp track and which is mounted rotatably in a driver, the latter being connected to the piston rod, and therefore, upon rotation of the ramp along a first rotation direction, the ramp track runs below the rotating roller. For the tensioning procedure, the ramp track can be rotated along the first rotation direction such that the roller runs on the region of inclination as far as the second plateau and the piston is thereby moved to its rear end position, wherein the tensioning unit is tensioned. For the dispensing procedure, starting from a contact of the roller with the second plateau, the tensioning device can rotate the ramp track along the first rotation direction until the roller runs over the transfer region and, on account of the tensioned tensioning unit, accelerates towards the first plateau, as a result of which the piston is moved towards the open dispensing end.
The device for administering a fluid can designed as a self-filling syringe. Here, a self-filling syringe is understood in particular as a syringe in which, during or as a result of the movement of the piston away from the dispensing end of the syringe, the fluid that is to be administered is brought into the cylinder, and in which, by means of the movement of the cylinder towards the dispensing end, the fluid that is to be administered is dispensed. The device for administering a fluid is preferably designed as a self-filling syringe for needle-free administration (in particular intradermal, subcutaneous or intramuscular administration) to animals and/or humans.
Of course, the device for administering a fluid can also be designed such that it is designed as a self-filling syringe with a needle at the dispensing end.
The first valve can be designed as a passive valve or as an active valve. Moreover, the second valve can be designed as a passive valve or an active valve. Here, a passive valve is understood in particular as meaning that the opening and closing of the valve is effected by a positive or negative pressure generated in the cylinder on account of the movement of the piston in the cylinder. Here, an active valve is understood in particular as a valve which can be opened and closed by means of an actuator. Here, an opened first or second valve is understood in particular as meaning that the desired fluidic connection between cylinder and dispensing end or feed channel is present. Here, a closed first or second valve is understood in particular as meaning that there is no fluidic connection present between cylinder and dispensing end or feed channel (or the desired fluidic connection, with the valve opened, is interrupted or blocked). The first valve can be designed as a nonreturn valve. Moreover, the second valve can be designed as a nonreturn valve.
The device for administering a fluid can be designed such that a movement of the piston along the first direction generates a negative pressure in the cylinder, and therefore, with the second valve opened, the fluid that is to be administered is sucked into the cylinder via the feed channel. In particular, the negative pressure generated can open the second valve. Moreover, the positive pressure in the cylinder, generated by the movement of the piston counter to the first direction towards the open dispensing end, can open the first valve, as a result of which the fluid that is to be administered from the cylinder is dispensed via the open dispensing end.
It will be appreciated that the features mentioned above and the features still to be explained below can be used not only in the specified combinations but also in other combinations or on their own, without departing from the scope of the present invention.
The invention is explained in even more detail below on the basis of exemplary embodiments, with reference being made to the appended drawings, which likewise disclose features essential to the invention. These exemplary embodiments are only illustrative and should not be construed as restrictive. For example, a description of an exemplary embodiment with a multiplicity of elements or components should not be construed as meaning that all of these elements or components are necessary for implementation. Rather, other exemplary embodiments can also contain alternative elements and components, fewer elements or components, or additional elements or components. Elements or components of different exemplary embodiments can be combined with one another, unless stated otherwise. Modifications and variations that are described for one of the exemplary embodiments can also be applicable to other exemplary embodiments. In order to avoid repetition, the same elements or corresponding elements in different figures are designated by the same reference signs and are not explained several times over. In the figures:
In the exemplary embodiment shown in
At its end facing away from the main portion 3, the handle portion 4 transitions into a base 8 in which, for example, a power supply (for example an accumulator) for the device 1 can be contained.
In the exemplary embodiment described here, the device 1, which can also be designated as administering device 1, is designed for the needle-free administration of the fluid to an animal. The administration preferably involves the intramuscular injection of the fluid which, for example, can be a pharmaceutical product, a vaccine or the like.
The administering device 1 has a cylinder/piston arrangement 10 (
Also formed at the front part 11 is the attachment 7, in which a second nonreturn valve 20 (
The second nonreturn valve 20 can be designated as an inlet valve, and the first nonreturn valve 15 can be designated as an outlet valve.
A piston 25 with a piston end 26 pointing towards the open dispensing end 14 is guided in the cylinder 13, wherein the piston 25 is in its rear end position in the sectional views in
The rear end (shown clearly in
Moreover, a compression spring 32, 33 (e.g. a helical spring) is arranged for each guide rod 29 and 30, the front ends of the compression springs 32, 33 each bearing on the plate 28, and their rear ends each bearing on an abutment of the rear part 12. In the position of the piston 26 shown in
Arranged at the rear end of the rear part 12 is a cover 35, which is not shown in the isometric view of the cylinder/piston arrangement 10 according to
The roller 40 runs on a ramp track 41 of a ramp 42 that rotates under the roller 40, wherein the ramp track 41 has a single winding, as can be seen in particular in
In
The ramp track 41 has a lower plateau 43, which is adjoined by a region of inclination 44, the latter extending as far as the upper plateau 45. The upper plateau 45 is adjoined by a transfer region 46, which merges into a transition flank 47 (rotation angle α1), which in turn leads to the first plateau 43. The rotation angle range from α0 to α2 thus equals 360°.
The transition flank 47 is distinguished by the fact that it runs virtually vertically, since it extends from the height z1 to the height z0 at a rotation angle (here α2). The transfer region 46 is thus the rotation angle range at which the height z1 decreases continuously starting from the upper plateau 45, until the rotation angle α2 (=transition flank 47) is reached. Thus, the rotation angle range of α1 to α2 covers the transfer region 46.
The ramp 42 is connected by a coupling 50 to a motor 51 (
After the discharging procedure, the ramp 42 is rotated again in the first rotation direction 52 by means of the motor 51, such that, as soon as the roller 40 makes contact with the ramp track 41 in the region of inclination 44, further rotation has the effect that the driver 31 is moved along the longitudinal direction of the piston 25 away from the open dispensing end 14, as a result of which the compression springs 32, 33 are tensioned again and reach their maximum tensioning when the roller 40 reaches the upper plateau 45. On account of the mechanical connection of the driver 31 to the guide rods 29 and 30, to the plate 28 and to the piston rod 25, this movement of the driver 31 has the effect that the piston 25 and thus the front piston end 26 are also moved in a direction away from the open dispensing end in the cylinder 13, and a negative pressure is thus built up. As soon as the built-up negative pressure is so great that the inlet valve 20 opens, the fluid is sucked through the inlet valve 20 and the radial bores 22 into the cylinder 13, such that the cylinder 13 is filled with the fluid.
When the roller 40 (which can also be designated as a cam or a barrel) has reached the upper plateau 45, the motor 51 stops, such that the cylinder/piston arrangement 10 is tensioned and therefore the administering device 1 is ready for the next administering procedure, which can be carried out by actuating the trigger 5.
The plate 28, the springs 32, 33 and guide rods 29, 30, the driver 31 with the roller 40, and the ramp 41 form, together with motor 51 and coupling 50, a tensioning device S for tensioning the cylinder/piston arrangement 10.
The administering device 1 moreover comprises a control unit 54 for controlling the motor 51 and all the other electrical components of the device 1.
In the case of the administering device 1, it is important that the rear end 60 of the cylinder 13 (
A first sealing element 61 and a second sealing element 62 can be spaced apart from the latter along the first direction (from left to right in
However, since the single-acting sealing element 61 does not seal off, or only poorly seals off, the rear end 60 of the cylinder 13 with respect to negative pressure in the pressure chamber 70, the second sealing element 62 is provided. In the exemplary embodiment described here, the second sealing element 62 is designed as a double-action sealing element 62 or a double-acting sealing element 62 (it can be an O-ring seal for example), which seals off the rear end 60 of the cylinder 13 with respect to negative pressure in the pressure space 70.
Since the first sealing element 61 seals off the rear end 60 when there is a positive pressure in the pressure space 70, then, compared to previously known solutions, the pressure on the second sealing element 62 in the event of a positive pressure in the pressure chamber 70 is no longer so high, and therefore the undesired wear on such an O-ring seal 62 is greatly reduced.
Moreover, a lubricating ring 63 can also be provided which is arranged between the cylinder 13 and the piston 25. It can be, for example, a felt ring or a sponge-like material. The lubricating ring 63 can have oil or grease applied to it for example, in order to ensure the best possible lubrication of the piston 25.
In the embodiment shown in
As can be clearly seen from the enlarged detailed view in
This results in a compact cylinder 13 which can be removed in its entirety from the device. This compact cylinder 13 can then be divided into its parts and, for example, only the rear cylinder part 64 along with the sealing rings 61 and 62 and the lubricating ring 63 need be replaced. It is of course also possible to replace only the first sealing ring 61 and second sealing ring 62 and the optional lubricating ring 63 during maintenance and to use the rear cylinder part 64 again.
In the embodiment shown in
In
While the invention has been described in connection with what is presently considered to be the most practical and preferred embodiments, it will be apparent to those of ordinary skill in the art that the invention is not to be limited to the disclosed embodiments. It will be readily apparent to those of ordinary skill in the art that many modifications and equivalent arrangements can be made thereof without departing from the spirit and scope of the present disclosure, such scope to be accorded the broadest interpretation of the appended claims so as to encompass all equivalent structures and products. Moreover, features or aspects of various example embodiments may be mixed and matched (even if such combination is not explicitly described herein) without departing from the scope of the invention.
Number | Date | Country | Kind |
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102020134181.4 | Dec 2020 | DE | national |