The present invention relates to improved device for micronization of solid materials which is based on the concept of disintegrator, and to its use.
Basic technical problem which is solved by the present invention is novel construction geometry of hitting elements (blades) of already known device for micronization of solid materials, based on the concept of disintegrator with two opposite rotating discs bearing said blades.
Second technical problem solved by the present invention is relative position of the blades with new shape on wreaths of the discs which perform micronization, with the goal to increase efficiency of the micronization process.
Milling is one of basic technological operations of chemical, food-processing, construction, and many other industries, wherein material is grinding to various fine levels of granulation or particles size.
Micronization is highly-effective kind of milling which provides direct production of very fine particles, typically from 5-50 μm, from starting material of relatively coarse particle size, e.g. 0.1-1 mm.
Technological operation of micronization is widely employed in production of active substances and excipients for pharmaceutical, cosmetic, and agrochemical industries; also in chemical industry (e.g. fillers, pigments), as well as many other fields.
Micronization can be carried out by prolonged milling in different kinds of classical mills, wherein the milling process is mainly effected by the collisions of particles of material being milled with hitting elements of device [A. D. Salman, M. Ghadiri, M. J. Hounslow: Handbook of powder technology, Vol. 12, Particle Breakage (2007) Elsevier]: (i) ball mill; (ii) rod mill; (iii) hammer mill; or (iv) vibration mill.
For each of mentioned mill concepts, there can be find improved versions in the literature [e.g. for ball mill, T. Orlandi: Grinding Process and a Continuous High-Capacity Micronizing Mill for its Implementation, U.S. Pat. No. 5,174,512 (1992) Snamprogetti S.p.A.].
Far more effective technics of micronizations are those predominantly based on mutual collisions of particles of material being micronized: (i) in suspension (wet milling) in colloidal mill; (ii) by dry milling in so-called jet-mill, which affects milling due to high number of particles collisions in the flow of compressed air [H. G. Zander, H. Bornefeld, B. M. Holl: Process and Device for Micronizing Solid Matter in Jet Mills, EP0276742 (1994) Bayer AG]; or in (iii) disintegrator [D. Muschenborn, R. Rautenbach: Impact Mill, U.S. Pat. No. 4,522,342 (1985); T. Lelas: Device for micronizing materials, HR990263 A2 (1999)].
The present invention involves an improved version of micronization device based on the concept of disintegrator, as described in the prior art [e.g. T. Lelas: Device for micronizing materials, HR990263 A2 (1999)].
Said disintegrator is based on the concept of two opposite discs which rotate by high speed in opposite directions. Discs bear certain hitting elements, blades, which mill/micronize particles of material during their passage through the device. Also, they provide high number of mutual collisions of particles of the material being micronized.
In the literature there are described devices with various shapes of the blades on the discs: (i) round-shaped blades; (ii) cubic-shaped blades; (iii) blades in the shape of elongated plates; and (iv) blades in the shape of slightly curved plates, without or with additional particular mechanic details (e.g. indented hitting surface) which eventually improve course of micronization process.
Such device is shown in
To solve said technical problems, the device for micronization of solid materials as shown in the
Wreaths of blades of different discs are faced one against another, in the manner that all wreaths of blades are identical, in the shape of the letter “T”. The blades are consisting of three wings, where two wings are dimensionally identical and placed under the right angle, whilst the third wing is dimensionally larger than the two former wings. Centerline of all three wings meet each other in the center of the blade, on the circle that goes through the half of the wreath.
The position of blade on each of discs is constructed by the way that one shorter wing of the blade is leaned for angle β in the rotating direction of the wreath, in relation to tangent which goes through the center of the blade. The angle β is 120°-140°. All blades of the same wreath are leaned in the same direction.
The present invention is shown in the
In housing (4) of the device, there are positioned two discs (6a, 6b), independently driven by motors (2a, 2b) through axles (3a, 3b) in a way that said discs (6a, 6b) do rotate in opposite directions; on each of discs (6a, 6b) there are positioned at least two or more wreaths of blades (8a, 8b) in such a manner that two neighbouring wreaths which belongs to different discs do rotate, relatively one to another, in opposite directions, thus forming an area wherein micronization of material is taking place; wreaths of blades (8a, 8b) of different discs (6a, 6b) are faced one against another.
On the
All blades (7) of wreaths (8a, 8b) are identical, of the shape of the letter “T”, and comprise of three wings (7a, 7b, 7c) (
Course of micronization process in the device from the present invention is the same as in the device from the prior art given on the
The influence of the shape of blades on efficiency of micronization has been studied by the use of micronization device shown in
Natural limestone mineral, chiefly calcium carbonate (CaCO3) by chemical composition, was selected as a model substance of hardness of 3 according to Mohs' scale. Starting material was of nominal particles size of 0-1 mm, of average particle size of 0.3-0.5 mm, which is commercially available as fine mineral filler for production of construction adhesives, plasters, etc.
Per 1 kg of thus samples of limestone mineral were micronized by the use of the device from the prior art shown in
Such prepared samples of micronized limestone mineral were subjected to particles size analyses by using MasterSizer 2000 (Malvern instruments) instrument. Results of Experiment-1 and Experiment-2 were shown in Table 1, and graphically in
The results showed unexpectedly increasing of efficacy of micronization process due to the use of the new design of blades in the shape of the letter “T” on the discs of the device. Increasing of efficacy of micronization process expressed as a ratio of:
1Ratio between percentages by volume (% V/V) of particles of analogous size obtained by the use of discs with blades from the prior art (FIG. 3; Experiment-1), and with discs containing blades in the shape of the letter “T” from the present invention (FIG. 4; Experiment-2).
From these results, unexpectedly positive effect of the new design of hitting elements, blades (7), on the discs (6a, 6b) of the micronization device is clear to those skilled in the art; this new design of the blades resulted in increasing of micronization efficiency of 17-19%.
At rotation of the discs (6a, 6b) of the device by external force, particles of a fluid pass from central part of discs toward their (outern) edges of hats, as shown in
In the
It seems that the major effect of blades (7) from the present invention is not increasing the energy to the fluid by minimal energy looses, what is the case at e.g. pumps or classical ventilators, but, with the shape of the blade, power energy mainly spend in a controlled manner on generation of turbulent areas (
The blades from the present invention in the shape of the letter “T” (
Described towards leaned position of the blades (β=βmax), shown in
The Use of Micronization Device from the Present Invention
It was found that average particles size of entering material being micronized in the present device can be between 0.1-0.5 mm at smaller, laboratory devices with diameter (Ø) of discs <500 mm. At larger devices with diameter of discs >500 mm, it can be 0.1-3 mm. The best option is to use starting materials with average particles size between 0.1-0.5 mm, what is usual in industry where these products are firstly subjected to coarse milling in some kind of ordinary mills like ball mills. Of course, here can be used starting materials with average particles size of smaller than 0.1 mm, what results in significant additional enhancement of micronization process efficiency.
Improved micronization device from the present invention was built from stainless steel 316. This device was successfully employed for micronization of wide variety of organic and inorganic substances which are of lower level of hardness according to Mohs scale (<5-6). When the hitting elements (blades) were built from very hard materials like tungsten carbide, the device from the present invention was successfully employed also for micronization of even harder substances which are in the Mohs scale ≧7, as achieved with the sand (quartz). Alternatively, basic material of micronization device blades, stainless steel 316, can be coated with the layer of tungsten carbide with almost the same improvements.
Improved micronization device from the present invention is successfully used for milling of pure substances or mixtures of several substances, which are, according to their chemical composition: (i) inorganic; (ii) organic; or (iii) mixed composition of organic and inorganic substances; from the classes of raw materials, intermediates or final products in pharmaceutical, cosmetic, food, agrochemical or construction industry, then in various kinds of chemical industries, agriculture, and in other fields of production.
For instance, the device can be effectively used in the production of active substances and excipients for pharmaceutical, food, and agrochemical industry.
As an example of pharmaceutically active substance herein is mentioned anti-inflammatory substance alclometasone-17,21-dipropionate which was successfully micronized with the device from the present invention yielding the product of increased bioavailability.
Additionally, as an example, here mentioned natural limestone mineral (chiefly CaCO3) contained small amounts of silicon dioxide in the form of quartz (SiO2). Commercially available limestone with average particles size of 0.1-0.5 mm, can be directly processed by the use of the micronization device from the present invention into highly micronized material of average particles size of <10 μm with approx. 10% of particles bellow 1 μm, what is very close to the area of nano-particles (e.g. the product from Example 1). Such product, applied on plants by foliar spraying as 0.5-2% aqueous suspension, provides a profound effects of calcium (Ca2+; from calcium carbonate) and silicon (Si; from quartz) fertilization. Analogous application of limestone mineral of commercially available particles size does not exhibit any physiological effects on plants.
Herein mentioned examples of the use of the micronization device from the present invention are only illustrative and do not include all possible technical applications.
For testing of the influence of the shape of blades (7) on discs (6a, 6b), the device with discs diameter (Ø) of 500 mm was used (
Particles size analyses were carried out on the MasterSizer 2000 instrument (Malvern Instruments).
Per 1.00 kg of limestone mineral (chiefly calcium carbonate; CaCO3) as model substance of average particles size of 0.3-0.5 mm, was subjected to micronization by the use of the device from the prior art shown in
Number | Date | Country | Kind |
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P20100464A | Aug 2010 | HR | national |
Filing Document | Filing Date | Country | Kind | 371c Date |
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PCT/HR2011/000033 | 8/19/2011 | WO | 00 | 1/23/2013 |