1. Technical Field
The present invention relates to visual rehabilitation, and more specifically, to visual rehabilitating (of visually impaired) and augmentation (e.g. of high-resolution color information) of the visual perception in the brain by applying sensual stimulations of different types.
2. Discussion of the Related Art
The use of neural stimulation as a means for rehabilitating neural and brain mechanisms is well known in the art. For example, clinical researches have shown recovery and rehabilitation of injured or dysfunctional visual systems. Some researchers have shown that a deliberate stimulation of neural tissues in which the stimulation represents visual data of an actual scene may help to develop the neural connections and revive the visual perception capabilities of the brain and the vision related neural system at least to some (quite limited) extent.
Sensory substitution devices are non-invasive human-machine interfaces which transform visual information into auditory or tactile inputs, and enable the blind to “see” using their other senses, offering, in principle, high-resolution visual information. One challenge is how sensory substitution devices can be used to provide high visual resolution, or high visual acuity. Another challenge is how congenitally blind individuals, who have never experienced sight, can learn to perceive high-resolution ‘vision’.
Several attempts were directed at restoring vision to the blind. One approach is by applying an electro-neural stimulation to vision nerves via electrodes, wherein the stimulation is based on a conversion of captured visual data into neural stimulation. Specifically, a device preferably worn on the head of a visually impaired person captures images of the scene which in turn are converted to electro-neural stimulation that is applied, via a set of electrodes, to the relevant portion of the neural tissue.
While some improvement in patients using the aforementioned device has been demonstrated, the limited number of electrodes yields unsatisfactory results. It should be noted however, that while increasing the number of electrodes is possible (from less than a hundred to over a thousand, for example) there is an inherent limitation of resolution in using a set of electrodes, due to the impracticality of coupling a very large number of vision nerves (of any type) with the electrodes. Another critical limitation is that the brain do not always (or usually) knows how to interpret the information arriving from the electrical stimulation as the brain was dramatically changed after years (or lifelong) of blindness. Despite the aforementioned attempts, the currently available sensory substitution devices provide poor resolution while other solutions lack the ability to provide the patient with a real perception of vision.
According to some embodiments of the present invention, a system for both rehabilitating vision related neural tissue and augmenting visual perception with high resolution and color information is provided. The system may include a capturing device configured to capture a video sequence of images of a scene; a processing unit configured to: (i) convert visual data derived from each captured image into at least one of: auditory representation and tactile representation, based on a first mapping; and (ii) convert the visual data of a respective captured image into a neural stimulation representation, based on a second mapping; a neural stimulator configured to generate neural stimulation onto a vision related neural tissue, wherein the neural stimulation is based on the neural stimulation representation; and an output unit configured to generate at least one of: an auditory stimulation and tactile output, based on the auditory representation and tactile representation respectively, wherein the neural stimulation, the auditory stimulation, and the tactile stimulation are carried out within a specified timeframe.
According to some embodiments of the present invention, a method of achieving both rehabilitation of vision related neural tissue and augmentation of visual perception with high resolution and color information is provided herein. The method may include the following stages: converting visual data derived from each captured image into an auditory or tactile representation, based on a first mapping; converting the visual data of a respective captured image into a neural stimulation representation, based on a second mapping; generating a neural stimulation, wherein the neural stimulation is based on the neural stimulation representation; generating an auditory or tactile stimulation, based on the auditory representation and tactile representation respectively; and applying within a specified timeframe: (1) the neural stimulation to a vision related neural tissue of the person and (2) the auditory stimulation and/or tactile stimulation to ears and portions of skin of the person, respectively, wherein the applying is usable for the several therapeutic purposes. For example, some therapeutic purposes may include: (i) rehabilitating the vision related neural tissue; (ii) developing vision-auditory neural pathways; (iii) developing vision-tactile neural pathways; (iv) providing alternative visual orientation; (v) providing an explanatory information for the neural stimulation; and (vi) providing increased resolution, color information and context to the neural stimulation which provides the visual qualia, being the feeling of vision. The latter outcome is particularly advantageous for late blinds people (which forms the great majority of blind worldwide).
Advantageously, embodiments of the present invention overcome the drawbacks of the existing approaches for visual rehabilitation. All existing approaches lack the ability to recover color vision which is critical not only for enhancement of the experience but is further crucial for enhancing the ability to recognize objects in natural settings and separate figures from background which is key computation needed for vision. Embodiments of the present invention thus create a hybrid system in which a first component stimulates or recovers the peripheral visual system in a bottom up manner to recover gray scale low-resolution qualia of vision (it is not possible so far to create systematic stimulation to achieve color vision) and a second component adds high-resolution perception and color information top-down using sounds and touch information.
These, additional, and/or other aspects and/or advantages of the embodiments of the present invention are set forth in the detailed description which follows; possibly inferable from the detailed description; and/or learnable by practice of the embodiments of the present invention.
For a better understanding of embodiments of the invention and to show how the same may be carried into effect, reference will now be made, purely by way of example, to the accompanying drawings in which like numerals designate corresponding elements or sections throughout.
In the accompanying drawings:
The drawings together with the following detailed description make apparent to those skilled in the art how the invention may be embodied in practice.
With specific reference now to the drawings in detail, it is stressed that the particulars shown are by way of example and for purposes of illustrative discussion of the preferred embodiments of the present invention only, and are presented in the cause of providing what is believed to be the most useful and readily understood description of the principles and conceptual aspects of the invention. In this regard, no attempt is made to show structural details of the invention in more detail than is necessary for a fundamental understanding of the invention, the description taken with the drawings making apparent to those skilled in the art how the several forms of the invention may be embodied in practice.
Before explaining at least one embodiment of the invention in detail, it is to be understood that the invention is not limited in its application to the details of construction and the arrangement of the components set forth in the following description or illustrated in the drawings. The invention is applicable to other embodiments or of being practiced or carried out in various ways. Also, it is to be understood that the phraseology and terminology employed herein is for the purpose of description and should not be regarded as limiting.
Embodiments of the present invention present a combination of neural stimulation together with either auditory or tactile stimulation (or both) for the purposes of arousing visual rehabilitation and reconstruction of original neural pathways. Additionally, the combined stimulation may further provide the blind patient with explanatory information for the neural stimulation. Another outcome is providing increased resolution, color and context to the neural stimulation which provides the visual qualia, being the feeling of vision.
The combining is correlated in a specified faun such that the two or three types of stimulation are useable to develop visual pathways in the central neural system. System 100 does so by capturing real-time images by a image capturing device 110 into a series of instrumental sound sweeps or tactile stimuli that covers the entire image in two seconds or less, together with matrix of electrophysiological stimulation electrodes which are capable of stimulating visual areas and so reflecting an image directly to the nerve system by using appropriately calibrated electrical stimulation, which fits the visual data.
The inventors have discovered that continuously applying electrical stimulation to the visual nerve system such that the electrical stimulation is correlated with a synchronous sensory stimulation wherein each one of the stimulations is a transformation of the visual data, will significantly increase the speed of rehabilitation in the visual system. The rate of rehabilitation of the visual nerve system using system 100 is significantly higher than the rate of rehabilitation of the visual nerve system with each one of the stimulations taken alone. This end is achieved since the auditory and/or tactile signal provide an explanatory signal to the direct neural stimulation. Put differently, the auditory and/or the tactile stimulations serve as a so-called “sensual interpreter” to the neural stimulation applied directly to the neural tissues. Advantageously, this combined stimulation takes advantage of the regenerative nature of the neural pathways in the brain.
Finally, the system further includes output unit such as earphones 120 configured to generate an auditory stimulation and a tactile output unit 130 such as, but not necessarily, a matrix of pins configured to generate a tactile stimulation. Both auditory stimulation and tactile stimulations are based on the auditory representation and tactile representation respectively. Thus, person 10 is presented with several representations of the same visual image. These stimulations can be used for several purposes. Some of the demonstrated applications are: (i) rehabilitating the vision related neural tissue; (ii) developing vision-auditory neural pathways; (iii) developing vision-tactile neural pathways; (iv) providing alternative visual orientation; (v) providing an explanatory information for the neural stimulation; and (vi) providing increased resolution and context to the neural stimulation which provides the visual qualia, being the feeling of vision. This latter outcome is particularly advantageous for late blinds people.
The inventors have discovered that by using complementary sensual stimulations, the advantages in terms of perception achieved by auditory or tactile stimulation are used to enhance the visual perception via the direct neural stimulation to the neural tissue of the visual system.
Consistent with one embodiment of the invention, the neural stimulator comprises a plurality of electrophysiological electrodes configured to convey electrophysiological signals. An exemplary neural stimulator may be in the form of a plurality of electrophysiological electrodes set in an N×M matrix layout. It is understood that other neural stimulators may be used in order to carry out the present invention.
In order to increase the affectivity of the cross-sensual stimulation, the neural stimulation, the auditory stimulation, and the tactile stimulation are carried out either simultaneously or within a specified timeframe of 1-2 seconds. Additionally, both the auditory stimulation and the tactile stimulation may be carried out in a form of a swipe or a scan of scene 30 so that person 10 receives these complementary stimulations over a period of time such as 0.5 to 2 seconds. It is understood that both delay time and scan time may be adjusted to fit the needs of the patients and further according to the treatments results.
Consistent with one embodiment of the invention, the first mapping (associated with auditory/tactile stimulation) is selected such the auditory representation and/or the tactile representation exhibit a resolution within a specified range containing the resolution of the neural stimulation representation. Thus, the resolution of the neural stimulation may be set to either a higher or lower level than the resolution level of the auditory/tactile stimulation, in accordance with specific needs of the patients. In some cases, as may be shown in
Similarly the auditory signal can be up to two orders of magnitude higher than the neuronal stimulation if needed. This too can be adjusted according to the performance and needs of the patient, first start with lower resolution and as performance improved increase resolution. This feature is advantageous in providing higher spatial resolution. For example, both 330B and 330D represent the two lower tips of the right legs of the table. However, in 330D the location and orientation of the legs is much more apparent than in 330B. Carrying out embodiments of the present invention will help to enhance the visual perception caused by the neural stimulation, with better spatial resolution and shape perception.
Consistent with one embodiment of the invention, the first mapping and the second mapping are adjustable in quality and quantity and may be selected such that any of the following applications: (i) rehabilitating of the vision related neural tissue, (ii) developing of the vision-auditory neural pathways, and (iii) developing of the vision-tactile neural pathways are maximized. The optimization may be carried out prior to treatment based on the patient's data or may be adjusted in response to the treatment results. Alternatively, the optimization may be carried in real-time during treatment and based on actual feedback from the patient.
According to some embodiments of the present invention, the system may further include a capturing device configured to capture said visual data from a scene. The capturing device can capture either still image or video sequences. Alternatively, the visual data may be derived from a restored retina of a patient. It is understood however, that the capturing device is not necessarily part of the systems and the visual data may be provided from an external source.
As can be seen in
Thus, table 310B and chair 320B may be represented by different musical instruments, different pitch or other means for auditorily distinguishing that in turn may help person 10 in distance perception of the neural stimulation so as to distinguish as shown in
By providing auditory signal indicative of color in the scene, the patient is provided with more visual information than can be provided by currently available sensory substitution devices which provide black & white only representation. Thus, the auditory-color representation not only enhances the “vision” experience but also provides valuable information of the scene, such as colors of a traffic light.
Consistent with one embodiment of the invention, first mapping is selected such that at least one of: shape and texture of objects contained within the visual data are converted into the tactile representation, while at least one of: shape, position and color of objects contained within the visual data are converted into the auditory representation.
The inventor has discovered that by carefully selecting the subset of colors and their respective auditory representation, better results in terms of color perception of the blind persons may be achieved. For example, assigning specified musical instrument chords for specified colors may improve the ability to distinguish between colors and the use of chords rather than pure tones may improve the ease of learning, the pleasantness of the sounds (which might have been a hard limitation on sensory substitution devices according to the prior art) and the overall training process.
The inventors have discovered that by carrying out embodiments of the present invention, blind patients can retrieve visual information in much higher resolution than was previously demonstrated by any of the sight rehabilitation alternatives either sensory substitution devices (SSDs) or prostheses available today, even following a relatively limited training of 30-100 hours. By way of illustration,
As will be appreciated by one skilled in the art, aspects of the present invention may be embodied as a system, method or computer program product. Accordingly, aspects of the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment (including firmware, resident software, micro-code, etc.) or an embodiment combining software and hardware aspects that may all generally be referred to herein as a “circuit,” “module” or “system.” Furthermore, aspects of the present invention may take the form of a computer program product embodied in one or more computer readable medium(s) having computer readable program code embodied thereon.
Any combination of one or more computer readable medium(s) may be utilized. The computer readable medium may be a computer readable signal medium or a computer readable storage medium. A computer readable storage medium may be, for example, but not limited to, an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any suitable combination of the foregoing. More specific examples (a non-exhaustive list) of the computer readable storage medium would include the following: an electrical connection having one or more wires, a portable computer diskette, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or Flash memory), an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing. In the context of this document, a computer readable storage medium may be any tangible medium that can contain, or store a program for use by or in connection with an instruction execution system, apparatus, or device.
Aspects of the present invention are described above with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems) and computer program products according to embodiments of the invention. It will be understood that each block of the flowchart illustrations and/or block diagrams, and combinations of blocks in the flowchart illustrations and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions/acts specified in the flowchart and/or block diagram block or blocks.
These computer program instructions may also be stored in a computer readable medium that can direct a computer, other programmable data processing apparatus, or other devices to function in a particular manner, such that the instructions stored in the computer readable medium produce an article of manufacture including instructions which implement the function/act specified in the flowchart and/or block diagram block or blocks.
While the invention has been described with respect to a limited number of embodiments, these should not be construed as limitations on the scope of the invention, but rather as exemplifications of some of the preferred embodiments. Other possible variations, modifications, and applications are also within the scope of the invention.
Filing Document | Filing Date | Country | Kind |
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PCT/IL2013/050349 | 4/23/2013 | WO | 00 |
Number | Date | Country | |
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61637039 | Apr 2012 | US |