The invention relates to a stopping device for a container equipped with a neck, as well as to a container provided with such a device. The invention also relates to a method for closing a batch of containers provided with a stopping device.
In the field of containers for medication, it is common to use a glass vial to preserve an active principle in the form of lyophilizate, power or liquid solution. Such a vial must be closed in a dry manner in order to maintain its content in a satisfactory preserving state, until the date it is used.
In order to hermetically seal off a vial, it is common to use a stopping device that consists of a elastomer stopper and plastic cap intended to be immobilized around the stopper to insulate the exterior.
WO-A-2007/063218 offers a stopping device, the cap of which consists of a ring and a body that allows maneuvering the locking means of the ring on the neck of a container. Moreover, WO-A-2007/129144 is known to integrate a deformable transmission element with thrust force into a stopping device which is intended to fade when a thrust force has been sufficiently transmitted to bring a body into a position where it activates the locking means of a cap on the neck of a container. FR-A-2 927 divulges the use of a linking veil that connects a central batch with a peripheral edge and which presents different rigidities on different deformation tracks. FR-A-2 908 396 offers a stopping device in which a ring has a curbed extremity towards the exterior and cooperates with an internal peripheral groove of a ring to maintain locking means in an immobilized position of the stopping device. These known devices offer overall satisfaction, particularly when they are used on vials, of which the neck has a diameter of 20 mm.
When these stopping devices are used to seal off vials that belong to a batch of vials installed within a freeze-drier, by exercising a thrust force divided over the different stopping devices to bring them into a closed configuration, the thrust force exercised by means of a common body called “pressure plate” is divided over the different stopping devices. When we use containers with a relatively small diameter, particularly containers with a neck of a diameter of 13 mm, it is economically speaking interesting to install a batch of previously equipped containers of stopping devices in a freeze-drier with the largest number of containers possible. In this case, the combined thrust force that is exercised by the pressure plate on each stopping device has a relatively weak intensity, equal to 25 Newtons for a classic freeze-drier. Under these conditions, it is important to minimize the necessary force to bring each stopping device into its usable configuration where it efficiently closes the neck of a container.
It is this problem that aims at dealing with the present invention by offering a stopping device in which the necessary energy to bring the device into a usable configuration is minimized.
In this regard, the invention relates to a stopping device of a container provided with a neck, whereby this device contains a stopper and plastic cap, suitable for covering both the neck and the stopper in place on the neck, whereby this cap consists of a ring, suitable for surrounding the stopper and the neck in mounted configuration and provided with locking means on the neck, as well as a handling body of the ring, suitable to be mounted on the ring and provided with first means for transmission to the ring of a thrust force and second activation means of locking means of the ring, while the ring and handling body, respectively, are provided with first retaining means and second retaining means that cooperate together to maintain the handling body in a holding position in relation to the ring, where it does not activate the locking means of the ring. In conformity with the invention, the handling body is mobile in translation only in the direction of the thrust force, and a second position where it also activates the locking means of the ring and where it is immobilized in relation to the ring in translation in the two directions, according to a direction that is parallel to the thrust force, while the handling body comprises a first cylindrical surface with a straight generatrix or in the shape of a truncated cone arranged facing the first retaining means of the ring, on the course of travel of the handling body between its first and second positions, and a second cylindrical surface with straight generatrix or in the shape of truncated cone arranged facing the locking means of the ring, on the course of travel of the handling body between its first and second positions. Additionally, the locking means of the ring comprise tabs that extend from a first continuous edge of this ring, in the direction of the second edge of the ring opposite its first, edge, while the diameter of a circle that passes the external radial parts of the locking tabs has a higher value than the external diameter of the first edge and that each tab is arranged in an opening with closed contour which crosses the ring according to a radial direction in relation to a longitudinal and central axis of this ring.
Thanks to the invention, the handling body can be brought from its holding position to its first position where it ensures, through its action on the locking means, the efficient adhesion of the device on the container. Then, the two cylindrical surfaces with a straight generatrix or in the shape of truncated cone allow for the frictions to be limited between the handling body and the ring during the movement of the handling body between its first and its second position. This results in the fact that the necessary force to bring the handling body from its first to the second position is of limited intensity, which allows for considering acting simultaneously on a large number of stopping devices or to run a control operation based on a calibrated force allowing to pass from the first to the second position of the handling body. In addition, the positioning of the locking tabs in the openings with closed contour and the fact that the edge of the ring is continuous gives a certain flexibility to the tabs that is sufficient to fulfill their function, while the ring is resistant, mechanically speaking.
According to the advantageous but non-obligatory aspects of the invention, such a device can incorporate one or several of the following characteristics taken in any combination that is technically acceptable:
The handling body comprises a buttress that prevents the handling body from traveling in relation to the ring, from the first position and extending to the second position, by cooperating with the first retaining means provided on the ring.
The handling body comprises an annular skirt and the first and second surfaces, as well as possibly the buttress mentioned above, are arranged on an internal surface of this skirt.
The locking means, on the one hand, and the handling body, on the other hand, are respectively provided with first and second immobilizing means that cooperate together in order to immobilize the handling body in translation in relation to the ring in the second position. In this case, the first immobilizing means advantageously consist at least of an overhanging element arranged on an external radial side of a tab, while the second immobilizing means consist at least of a compartment in reception cavity of the overhanging element when the handling body is in its second position.
The first retaining means are arranged on deformable bands that extend, according to a direction that is parallel to the thrust fort, between an annular part of the ring intended to support on an exposed side of the stopper and annular edge of the ring from which the locking means extend.
A lid is connected with the ring and it insulates a central opening of the ring from the exterior that gives access to an exposed surface of the stopper, while the handling body consists of an annular skirt that surrounds the stopper, except at the level of a notch arranged in a higher edge of the skirt opposite the container in a mounted configuration of the device and when a radial clearance is arranged between the lid and the higher edge of the skirt, at least adjacent to a zone of the skirt diametrically opposite the notch.
The handling body consists of an annular skirt with a circular section that radially surrounds the ring when the handling body is in the holding position and in the first and second positions, while the exterior diameter of the skirt is less than 16.5 mm, preferably between 15.8 mm and 16.2 mm.
The invention also relates to a container equipped with a stopping device as mentioned above.
To conclude, the invention relates to a method for closing a batch of containers as mentioned above, whereby this method consists of the following phases:
a) preassemble each stopping device with its stopper and its cap in a holding position,
b) pre-mount the devices on the necks of containers by engaging their stoppers in these necks,
c) exercise, by means of a pressure body, a common thrust force on all of the devices, in such a way to completely engage the stoppers in the necks, and to bring the handling body of each stopping device in its first position, in its second position or in an intermediary position between these first and second positions,
d) exercise individually on each handling body of the stopping devices, a thrust force calibrated in a direction of travel of the handling body from its first position towards its second position,
e) determine if the handling body has reached its second position at the end of phase d), and
f) if the result of the phase e) is negative, identify the stopping device as incorrectly mounted on the corresponding container.
The invention will be better understood and other advantages of this invention will appear more clearly in the light of the description that will follow an embodiment of a stopping device, of a container and of a method in conformity with its principle, given uniquely by way of example and done with reference to the annexed drawings in which:
In
When a predetermined amount of product P has been introduced in vial 1, pipette 2 is removed and a stopping device 50 is placed on neck 12.
Device 50 consists of an elastomer stopper 51 in adapted form to be partially introduced in neck 11, by resting completely on side 131 of neck ring 13 opposite bottom 14 of vial 1. Once it is in place in neck 12, stopper 51 separates the content of vial 1 from the exterior.
Device 5 also consists of a cap 52 intended to cover and insulate stopper 51 and neck 12 in closed configuration of stopping device 50.
As it is evident from
Cap 52 also consists of a handling body of ring 53, comprised of a plastic crown 54 and which is intended to form the external peripheral cover of cap 52. Additionally, cap 52 also consists of a lid 56 that is also made out of plastic. This lid 56 is completely in rotational symmetry about a central axis X56.
541 is marked as the edge of crown 54 which is oriented towards vial 1 in an installed configuration of cap 52 on this vial. This edge 541 can be qualified as being “lower” to the extent that it is oriented towards the bottom in the configuration of
Top edge 542 of crown 54, which is opposite edge 541, is provided with a notch 543. With the exception of this notch, crown 54 is in rotational symmetry about an axis X54.
Ring 53 is centered on an axis X53 which is aligned with the axes X54 and X56 in assembled configuration of cap 52, whereby this axis is mixed up with a central axis X52 of cap 52.
Ring 53 consists of an annular part 531 that defines a central opening 532 through which it, is possible to access the top surface 511 of stopper 51 if need be.
561 is marked as the internal surface of lid 56, in other words, its surface is turned towards stopper 51 in mounted configuration of device 50 on vial 1. Lid 56 is provided with a skirt 562 centered on axis X56 and which extends parallel to this axis from surface 561.
During the manufacturing of cap 52, lid 56 is brought onto ring 53 by bringing closer surface 561 of part 531, by introducing skirt 562 in opening 532 and by uniting lid 56 on part 531 through merger of four platforms 563 arranged, for that purpose, on surface 561 and equally distributed around skirt 562.
When lid 56 has been fixed on ring 53, crown 54 is engaged around elements 54 and 56 in such a way that it demarcates the maximum radial girth of cap 52 in relation to axis X52.
In practice, the geometry of the pieces 53, 54 and 56 is chosen in such a way that the maximum external diameter D54 of crown 54 has value lower than 16.5 mm, preferably between 15.8 and 16.2 mm, yet preferably equal to 16 mm.
Under these conditions, when a vial 1 is used of which body 16 has a diameter that is equal to 16 mm, which is common for certain medications, cap 52 mounted on vial 1 does not pass or only passes the body of vial 1 a little bit, in a radial direction in relation to axis X1. This allows for vials 1, which are previously equipped with stopping device 50, to juxtapose on a shelf of a freeze-drier with high density, resulting from the relatively weak diameter of the bodies of these vials without the risk that the vials are destabilized by the stopping devices they support.
Ring 53 consists of five bands 533 that extend from part 531 until the lower edge of ring 53 which is formed by a continuous ring 534 around axis X53. External radial edge 5311 of part 531 defines a second edge or top edge of ring 53 and the bands 533 extend between edges 534 and 5311.
Each band 533 is provided with an external rib 535 that juts out radially towards the exterior in relation to axis X53 in relation to this tab. A window 536, i.e. a open zone with closed contour that puts the interior volume of ring 53 and the exterior in contact, is defined between each pair of two adjacent bands 533.
A locking tab 537 extends from ring 534 in each window 536. Taking into account the intrinsic flexibility of the material that makes up ring 53, each tab 537 can pivot around its base in relation to edge 534. In other words, each tab 537 can be more or less folded towards the interior of ring 53 in function of the forces it endures.
5371 is marked as the free edge of tab 537 and 5372 is marked as its exterior surface that adjoins this free edge. Exterior surface 5372 of each tab 537 is in the shape of a piece of cone-shaped surface 5373, centered on axis X53 and converging in the direction of edge 534. Surface 5372 forms thus the top external peripheral surface of a tab 537 while its surface 5373 forms a lower external peripheral surface. The respective diameters of surfaces 5372 and 5373 of a tab are chosen in such a way that a spout with circular arch 5374 is formed at the junction between these surfaces and defines a shoulder 5375 on the side of surface 5373. The spouts 5374 form the external radial parts of tabs 537.
D534 is marked as the exterior diameter of edge 534. D537 is marked as the diameter of an imaginary circle C537 centered on axis X53 and passing by the spouts 5374. In a non-tight position of locking tabs 537, the value of the diameter D537 is higher than that of the diameter D537, by at least 1.5 mm. Even when crown 54 surrounds the locking tabs 537, as envisioned above, the diameter D537 has a value that is higher than diameter D534, whereby the difference between these values is reduced.
Ring 53 on the interior of the junction zone between band 533 and part 531 is provided with ribs 538 intended to superficially penetrate in stopper 51 in order to immobilize this stopper in ring 53 and in cap 52.
Essentially, crown 54 consists of a skirt 544 that extends between edges 541 and 542, which is cylindrical to the circular section and of which 545 is marked as the external radial surface and 546 as the internal radial surface.
Surface 546 is provided with a rib 5461 that extends in the direction of axis X54 and which is demarcated by a top surface 5462 perpendicular to axis X54 and an lower surface 5463 converging in the direction of edge 541.
Surface 546 is also provided with a peripheral groove 5464, the height H1 of which is measured parallel to axis X54 is sufficient to receive the ribs 535 of bands 533 in a configuration where crown 54 is in a holding position in relation to ring 53. This configuration is represented in
Surface 546 also consists of a first cylindrical surface with straight generatrix 5465 that extends between rib 5461 and edge 542 and a second surface 5466 in the shape of truncated cone, splitting in the direction of edge 541 and which extends between groove 5464 and edge 541. Surfaces 5465 and 5466 are centered on axis X53.
The angle at the top of surface 5466 is less than 10°, preferably equal to 7°.
When lid 56 has been welded on ring 53, as explained above, crown 54 is engaged around elements 53 and 56 thanks to a pre-assembly axial force E1, i.e. parallel to axes X52, X53, X54 and X56 which are then merged. This results in the fact that skirt 544 is brought around bands 533. This movement is followed until ribs 535 move into groove 5464 and are locked in there. The sliding of crown 54 in relation to ring 53 takes place thanks to the elasticity of bands 533 that can elastically deform when their respective ribs 535 slid along surface 5466 of crown 54, prior to moving into groove 5464. In other words, the geometry of ring 53 gives bands 533 a sufficient flexibility so that the setup of crown 54 around elements 53 and 56 is easy. In practice, bands 53 extend each, in relation to axis X53 on an angular sector at an angle at the top less than 30°, preferably 25°, which gives them proper elasticity.
When cap 52 has been pre-assembled, it is possible to put stopper 51 in it by introducing it on the inside of ring 53 until ribs 538 superficially penetrate in stopper 51, which assures that the stopper remains in the ring. Alternatively, stopper 51 can be placed on neck 12 of vial 1, as presented in
Equipped vial 1 of device 50 can thus be introduced in a freeze-drier 300 within a batch of vials 1. In
On the inside of a freeze-drier, as presented in
The sum of forces E′2 is equal to the force E2.
In the configuration of
The application of force E2 results in the progression of crown 54 of each cap 52 in the direction of the bottom 14 of each of vials 1, as presented by the passage from the configuration of
The truncated cone nature of surface 5466 gives a progressive character to the tipping over of the locking tabs 537 from the position of
Annular part 531 comes thus in contact with the top surface 511 of stopper 31 which stops the progression of ring 53 in the direction of bottom 14. The continuation of the application of force E2 on crown 54 of each device 50 results in chasing rib 535 of each band 533 on the exterior of groove 5464 by elastic deformation of bands 533, which allows crown 54 to attain the positions of
This movement continues until the configuration of
When ring 54 is in its first position of
Ideally, in terms of the action of actuator 302, i.e. in the configuration of
As spouts 5374 of tabs 537 slide on surface 5466 during the travel from cap 54 of the position of
In the configuration of
In terms of lowering movement of plate 301, it is possible to extract vials 1 of freeze-drier 300 and to submit each in turn to a calibrated individual force E3, the intensity of which is for instance equal to 20 Newtons. The application of this force E3 allows to slide crown 54 in the direction of the bottom 14, i.e. approach its edge 541 of body 16 of vial 1, by sliding around elements 53 and 56. This sliding movement is hardly slowed down since the single point of contact between crown 54 and ring 53 is the support zone of spouts 5374 on surface 5466, which induces a weak friction force.
Taking into account this weak friction force between pieces 53 and 56, force E3, which has a relatively weak intensity, is sufficient to normally bring ring 54 of each device 50 in the configuration of
As force E3, which is necessary to bring crown 54 from its position of
If such is not the case, vial 1 is identified as presenting a defect in the measure where stopping device 50 is not correctly mounted on vial 1. This vial 1 is thus eliminated from the chain of production. In other words, force E3 has a double function: it allows to bring all devices 50, which equip vials 1 from freeze-drier 300 in the configuration of
In the configuration of
This allows to exercise a wrenching force E4 of lid 56 in relation to ring 53, to access opening 532 and, through the latter, to the top surface 511 of stopper 51.
A radial clearance J is defined between edge 564 of lid 56 and the part of surface 5465 of skirt 544 which is located in proximity to this edge in this configuration. This clearance J allows force E4 to effectively detach stopper 56 from ring 53 by breaking up the welded points that results in the merger of platforms 563 and by extracting skirt 562 from opening 532. Clearance J is arranged on the main part of the periphery of lid 56, between this lid and edge 542. Alternatively, it can only be arranged in the vicinity of the zone of skirt 544 opposite notch 543 since it is in the vicinity of this zone that lid 56 must move forward laterally towards the left side in
We notice in
The invention has been described in the case where surface 5465 is cylindrical while surface 5466 is in the shape of a truncated cone. Alternatively, surface 5466 can be cylindrical with a circular base. According to another variable, surface 5466 can also be slightly in the shape of truncated cone with a clearance angle of a few degrees, less than 4° that aims at facilitating the release of crown 54.
The constituent elements of cap 52 can be molded in polyoxymethylene (POM) or in an equivalent type of material.
It will be appreciated by those skilled in the art that changes could be made to the embodiments described above without departing from the broad inventive concept thereof. It is understood, therefore, that this invention is not limited to the particular embodiments disclosed, but it is intended to cover modifications within the spirit and scope of the present invention as defined by the appended claims.
Number | Date | Country | Kind |
---|---|---|---|
1059682 | Nov 2010 | FR | national |
This application is a Section 371 of International Application No. PCT/EP2011/070815, filed Nov. 23, 2011, which was published in the French language on May 31, 2012, under International Publication No WO 2012/069538 A1 and the disclosure of which is incorporated herein by reference.
Filing Document | Filing Date | Country | Kind | 371c Date |
---|---|---|---|---|
PCT/EP2011/070815 | 11/23/2011 | WO | 00 | 5/30/2013 |