Claims
- 1. A method of contrast enhanced ultrasonic diagnostic imaging comprising: administering to a subject a contrast enhancing amount of spheres or particles comprising a matrix enclosing a contrast agent which reflects sound waves, said matrix being a biocompatible, biodegradable, non-immunogenic non-polyamino acid synthetic polymer; and generating an ultrasonic image of said subject.
- 2. The method of claim 1 wherein said synthetic polymer matrix comprises a synthetic acrylate polymer matrix.
- 3. The method of claim 1 wherein the synthetic polymer is stabilized by means of covalent bonds.
- 4. The method of claim 1 wherein the spheres or particles have diameters in the range 0.01-1000 .mu.m.
- 5. The method of claim 1 wherein the spheres or particles have diameters less than 1 .mu.m.
- 6. The method of claim 1 wherein particles built up of conglomerates of smaller particles or spheres are administered.
Priority Claims (1)
Number |
Date |
Country |
Kind |
8307060 |
Dec 1983 |
SEX |
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Parent Case Info
This application is a continuation of abandoned application Ser. No. 08/186,096 filed Jan. 24, 1994, which is a continuation of abandoned application Ser. No. 08/043,982 filed Apr. 7, 1993, which is a continuation of abandoned application Ser. No. 07/888,305 filed May 27, 1992, which is a continuation of abandoned application Ser. No. 07/693,031 filed Apr. 30, 1991, which is a continuation of abandoned application Ser. No. 07/278,326 filed Nov. 30, 1988, which is a continuation of abandoned application Ser. No. 06/775,047 filed Aug. 15, 1985.
US Referenced Citations (21)
Foreign Referenced Citations (2)
Number |
Date |
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8633082 |
Jan 1983 |
AUX |
0136812 |
Aug 1984 |
EPX |
Continuations (6)
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Number |
Date |
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Parent |
186096 |
Jan 1994 |
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Parent |
43982 |
Apr 1993 |
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Parent |
888305 |
May 1992 |
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Parent |
693031 |
Apr 1991 |
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Parent |
278326 |
Nov 1988 |
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Parent |
775047 |
Aug 1985 |
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