Claims
- 1. In a method for prenatal testing of a child, the improvement comprising testing for Down syndrome, comprising the steps of:
- (a) preparing nucleic acid probes which hybridize to the human DYRK gene;
- (b) labeling said probes so as to make their presence in a cell detectable;
- (c) obtaining cells from said child;
- (d) exposing said cells to said probes; and
- (e) detecting specific binding of three probes in a single nucleus of a cell.
- 2. The method of claim 1 wherein the probe is radiolabelled, immunolabelled or labeled with fluorescence.
Parent Case Info
This application claims priority to a Provisonal Application Ser. No. 60/045,604, filed May 5, 1997.
REFERENCE TO GOVERNMENT INTEREST
This invention was made in the course of contract DE-AC03-76SF0098 between the United States Department of Energy and the University of California for the operation of Lawrence Berkeley Laboratory. The United States Government has certain rights to this invention.
Non-Patent Literature Citations (3)
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Simpson et al, Ann. NY Acad. Sci. 731:1-8, 1994. |