Claims
- 1. A diarylacetylene of the formula I ##STR12## where R.sup.1 and R.sup.2 are each hydrogen or methyl, R.sup.3 is hydrogen, methyl, hydroxy or C.sub.1 -C.sub.6 -alkoxy, R.sup.4 is hydrogen, methyl or methoxy, R.sup.5 is hydrogen, halogen, methoxy or C.sub.1 -C.sub.4 -alkyl, A is methylene or ethylene radical which is unsubstituted or substituted by C.sub.1 -C.sub.4 -alkyl or is --CH.dbd.CH--, --CHOH--CH.sub.2 -- or --CO--CH.sub.2 -- and R.sup.6 is methyl, nitrile, CH.sub.2 --OR.sup.8, --CH.sub.2 --NHR.sup.9, --COR.sup.11 or --CH.dbd.CH--COOH, where R.sup.8 is hydrogen, C.sub.1 -C.sub.4 -alkyl or C.sub.1 -C.sub.4 -alkanoyl, R.sup.9 is hydrogen or C.sub.1 -.sub.6 -alkanoyl and R.sup.11 is hydrogen or NH.sub.2, and its physiologically tolerated salts.
- 2. The compound of claim 1 which is 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphth-2-yl)-ethynyl]-benzonitrile.
- 3. The compound of claim 1 which is 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphth-2-yl)-ethynyl]-benzaldehyde.
- 4. The compound of claim 1 which is 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphth-2-yl)-ethynyl]-benzyl alcohol.
- 5. A therapeutic composition comprising a pharmaceutically acceptable carrier and an effective amount of a compound according to claim 1 as the active compound.
- 6. The method of treating dermatological disorders in a patient suffering therefrom which comprises administering an effective amount of a compound according to claim 1.
Priority Claims (1)
Number |
Date |
Country |
Kind |
3434946 |
Sep 1984 |
DEX |
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Parent Case Info
This application is a division of application Ser. No. 07/222,901, filed on Jul. 22, 1988, which is now U.S. Pat. No. 4,994,489, which was a divisional of Application Ser. No. 06/778,256, filed on Sep. 20, 1985, which is now U.S. Pat. No. 4,806,558.
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Foreign Referenced Citations (1)
Number |
Date |
Country |
3434948 |
Sep 1984 |
EPX |
Non-Patent Literature Citations (1)
Entry |
Wuest et al. Chem. Abstracts, vol. 105, No. 19; 172069g (1986). |
Divisions (2)
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Number |
Date |
Country |
Parent |
222901 |
Jul 1988 |
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Parent |
778256 |
Sep 1985 |
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