Claims
- 1. A propenoic acid compound represented by the formula (II) or a pharmacologically acceptable salt thereof: ##STR83## wherein R.sup.15 represents optionally substituted aryl or optionally substituted heteroaryl; and
- R.sup.16 represents hydrogen, lower alkyl, lower alkenyl, lower alkynyl or a group represented by formula --W--Q wherein W is a lower alkyl group, and Q represents optionally substituted aryl, optionally substituted heteroaryl, cycloalkyl, cyano, hydroxyl, lower alkoxy, acyloxy, carboxyl or a group represented by formula --NR.sup.9 R.sup.10 wherein R.sup.9 and R.sup.10 may be the same or different from each other and each represents hydrogen, lower alkyl, acyl, carbamoyl or alkylcarbanoyl, or alternatively R.sup.9 and R.sup.10 may represent, together with the nitrogen atom to which they are bonded, a cyclic group; provided that R.sup.16 is not an optionally substituted aryl when R.sup.15 is an optionally substituted aryl.
- 2. A propenoic acid compound represented by the formula (Ill) or a pharmacologically acceptable salt thereof: ##STR84## wherein R.sup.17 represents optionally substituted aryl or optionally substituted heteroaryl; and
- R.sup.18 represents hydrogen, lower alkyl, lower alkenyl, lower alkynyl or a group represented by formula --W--Q wherein W is a lower alkyl group, and Q represents optionally substituted aryl, optionally substituted heteroaryl, cycloalkyl, cyano, hydroxyl, lower alkoxy, acyloxy, carboxyl or a group represented by formula --NR.sup.9 R.sup.10 wherein R.sup.9 and R.sup.10 may be the same or different from each other and each represents hydrogen, lower alkyl, acyl, carbamoyl or alkylcarbanoyl, or alternatively R.sup.9 and R.sup.10 may represent, together with the nitrogen atom to which they are bonded, a cyclic group.
Priority Claims (4)
Number |
Date |
Country |
Kind |
5-177278 |
Jun 1993 |
JPX |
|
5-202903 |
Jul 1993 |
JPX |
|
5-227924 |
Aug 1993 |
JPX |
|
5-237188 |
Aug 1993 |
JPX |
|
Parent Case Info
This is a Division of application Ser. No. 08/258,634, Jun. 10, 1994, now U.S. Pat. No. 5,541,213.
Foreign Referenced Citations (5)
Number |
Date |
Country |
0225522 |
Jun 1987 |
EPX |
0278090 |
Aug 1988 |
EPX |
0299209 |
Jan 1989 |
EPX |
0497258 |
Aug 1992 |
EPX |
0516941A1 |
Sep 1992 |
EPX |
Non-Patent Literature Citations (1)
Entry |
Bernard et al, Pharmazie, 1986, vol. 41, No. 8, pp. 560-562. |
Divisions (1)
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Number |
Date |
Country |
Parent |
258634 |
Jun 1994 |
|