Claims
- 1. A compound of structural formula: ##STR184## or a pharmaceutically acceptable salt thereof, wherein, R is
- (1) hydrogen,
- (2) C.sub.1-3 alkyl,
- (3) C.sub.2-3 alkenyl,
- (4) phenyl-C.sub.1-3 alkyl,
- (5) C.sub.3-6 cycloalkyl,
- (6) C.sub.3-6 cycloalkyl-C.sub.1-3 alkyl, or
- (7) dimethylaminopropyl;
- R.sup.1 is
- (1) hydrogen,
- (2) C.sub.1-3 alkyl,
- (3) C.sub.2-3 alkenyl,
- (4) phenyl-C.sub.1-3 alkyl, or
- (5) C.sub.3-6 cycloalkyl;
- R.sup.2 is
- (1) hydrogen,
- (2) C.sub.1-3 alkyl,
- (3) C.sub.2-3 alkenyl,
- (4) phenyl-C.sub.1-3 alkyl,
- (5) C.sub.1-3 alkoxy, or
- (6) dimethylaminopropyl; and
- the dotted line is a single or double bond.
- 2. The compound of claim 1, or a pharmaceutically acceptable salt thereof, wherein R is hydrogen, C.sub.1-3 alkyl, or benzyl; R.sup.1 and R.sup.2 are hydrogen or C.sub.1-3 alkyl; and R.sup.3 and R.sup.4 are hydrogen.
- 3. The compound of claim 1 or a pharmaceutically acceptable salt thereof, wherein the dotted line is a single bond.
- 4. The compound of claim 2 or a pharmaceutically acceptable salt thereof wherein the dotted line is a single bond.
- 5. The compound of claim 4 which is 13-methyl-5,6,7,12-tetrahydrodibenzo[a,d]cycloocten-5,12-imine or a pharmaceutically acceptable salt thereof.
BACKGROUND OF THE INVENTION
This is a division of application Ser. No. 80,896 filed Oct. 1, 1979, now U.S. Pat. No. 4,329,465. which is a continuation-in-part of copending application, Ser. No. 917,044, filed June 19, 1978 which in turn is a continuation-in-part of application, Ser. No. 834,343, filed Sept. 19, 1977, both now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3717641 |
Kocsis et al. |
Feb 1973 |
|
3907999 |
Christy |
Sep 1975 |
|
4009273 |
Weddec et al. |
Feb 1977 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
532014 |
Feb 1973 |
CHX |
Non-Patent Literature Citations (1)
Entry |
Engelhardt et al., Journal of Medicinal Chemistry, 11, 325, (68), p. 327. |
Divisions (1)
|
Number |
Date |
Country |
Parent |
80896 |
Oct 1979 |
|
Continuation in Parts (2)
|
Number |
Date |
Country |
Parent |
917044 |
Jun 1978 |
|
Parent |
834343 |
Sep 1977 |
|