Claims
- 1. A method of therapy or prophylaxis of a disease associated with reversible airways obstruction in a patient which comprises administering to said patient an effective amount to alleviate said disease of a compound of formula (I): ##STR18## wherein R.sup.1 and R.sup.2 each represent a hydrogen atom or a C.sub.1-3 alkyl group, with the proviso that the sum total of carbon atoms in R.sup.1 and R.sup.2 is not more than 4;
- X represents a C.sub.1-6 alkylene, C.sub.2-6 alkenylene or C.sub.2-6 alkynylene chain;
- Y represents a bond, or a C.sub.1-4 alkylene, C.sub.2-4 alkenylene or C.sub.2-4 alknylene chain with the proviso that the sum total of carbon atoms in X and Y is not more than 8;
- Ar represents a phenyl group substituted by a group --NR.sup.5 COR.sup.6, where R.sup.5 represents a hydrogen atom or a C.sub.1-4 alkyl group and R.sup.6 represents a hydrogen atom or a C.sub.1-4 alkyl, C.sub.1-4 alkoxy or --NR.sup.3 R.sup.4 group where R.sup.3 and R.sup.4 each represent a hydrogen atom, or a C.sub.1-4 alkyl group or Ar is a phenyl group substituted by a group --(CH.sub.2).sub.r R.sup.7 where r is 0 or 1 and R.sup.7 is --COR.sup.9 where R.sup.9 represents hydroxy, C.sub.1-4 alkoxy or a group --NR.sup.3 R.sup.4 ; or a physiologically acceptable salt or solvate thereof.
- 2. A method of therapy or prophylaxis according to claim 1, wherein the disease associated with reversible airways obstruction is asthma or chronic bronchitis.
Priority Claims (2)
Number |
Date |
Country |
Kind |
8426191 |
Oct 1984 |
GBX |
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8525321 |
Oct 1985 |
GBX |
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Parent Case Info
This is a divisional of co-pending application Ser. No. 06/918,317 filed Oct. 14, 1986 now U.S. Pat. No. 4,943,591.
US Referenced Citations (7)
Foreign Referenced Citations (8)
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EPX |
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DEX |
2210414 |
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GBX |
Divisions (1)
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Number |
Date |
Country |
Parent |
918317 |
Oct 1986 |
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