Indena Pharmaceuticals Natural Active Principals from Medicinal Plants; http://www.indena.it/pharmac.htm, Oct. 2000.* |
Balch et al. Prescription for Nutritional Healing; Second edition, pp. 20-21 and 47-48, 1997.* |
Revilla et al. Comparison of Several Procedures Used for the Extraction of Anthocyanins from Red Grapes; Journal of Agricultural and Food Chem., (1998), 46 (11) pp. 4592-4597.* |
Stedman's Medical Dictionary; definition of ‘extract’; 27th Ed.* |
Cao et al., “Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables,” Am J. Clin. Nutr., 1998, 68:1081-1087. |
Dallas et al., “Degradation of oligomeric procyanidins and anthocyanins in a Tinta Roriz red wine during maturation,” Vitis, 1995, 34(1):51-56. |
Folts et al., “Moderate alcohol consumption, CAD, and myocardial ischemia,” J. Myocardial Ischemia, 1994, 6(8):33-40. |
Hashimoto et al., “Effect of Acute Intake of Red Wine on Flow-Mediated Vasodilation of the Brachial Artery,” Am. J. Cardiol., 2001, 88:1457-1460. |
Morris et al., “Effects of Fruit Maturity, Juice Storage, and Juice Extraction Temperature on Quality of ‘Condord’ Grape Juice,” J. Amer. Soc. Hort. Sci., 1986, 111(5):742-746. |
Preuss et al., “Effects of Niacin-Bound Chromium and Grape Seed Proanthocyanidin Extract on the Lipid Profile of Hypercholesterolemic Subjects: A Pilot Study,” J. Med., 2000, 31(5 & 6):227-245. |
Singleton and Rossi, Jr., “Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents,” Am. J. Enol. Vitic, 1965, 16:144-158. |
Strong, “Atherosclerosis in the Young: Risk and Prevention,” Hospital Practice, 1999, pp. 15, 16, and 19. |
Strong et al., “Prevalence and Extent of Atherosclerosis in Adolescents and Young Adults,” JAMA, 1999, 281(8):727-735. |
Human Drugs: Melaleuca; Idaho Falls, ID/Knoxville, TN, facility; Warning Letter Bulletin, Jul. 28, 1997, vol. 5, No. 15, ISSN: 1069-4218, Washington Information Source, Newsletter, XP-002216023, Warning Letter No. 97-NSV-08. |
Formica and Regelson, “Review of the Biology of Quercetin and Related Bioflavonoids,” Food Chem. Toxicol., 1995, 33(12):1061-1080. |
E. Bombardelli, Phytosome®: New Cosmetic Delivery System, Boll. Chim. Farmaceutico, (Dec. 1991). |
Demrow et al., “Administration of Wine and Grape Juice Inhibits in Vivo Platelet Activity and Thrombosis in Stenosed Canine Coronary Arteries”, Circulation, 91(4):1182-1188 (1995). |
Folts, “An In Vivo Model of Experimental Arterial Stenosis, Intimal Damage, and Periodic Thrombosis”, Circulation, 83(6) Supplement IV, pp. 3-14 (1991). |
Folts, “Drugs for the Prevention of Coronary Thrombosis: From an Animal Model to Clinical Trials”, Cardiovascular Drugs and Therapy, 9:31-43 (1995). |
Folts et al., “Moderate alcohol consumption, CAD, and myocardial ischemia”, J. Myocardial Ischemia, 6(8):33-40 (1994). |
Folts et al., “Possible Platelet Thrombi Formation in Dog and Human Femoral Arteries”, Tex. Heart Inst. J., 9:19-26 (1982). |
Folts, J.D., “Platelet Aggretation in Partially Obstructed Vessels and its Elimination with Aspirin”, Circulation, 54(3):365-370 (1976). |
Eichhorn et al., Spontaneous Alterations in Coronary Blood Flow Velocity Before and After Coronary Angioplasty in Patients With Severe Angina:, J. Am. Coll. Cardiol., 17:43-52 (1991). |
Waterhouse et al., “The Phenolic Phytochemicals in Wine, Fruit and Tea: Dietary Levels, Absorption and Potential Nutritional Effects”, Hyper Nutri. Foods, Ed. Finley et al, Agscience Inc., Auburndale, Fl, pp. 219-238 (1997). |
Folts, J.P., “Three glasses of Grape But Not Orange or Grapefruit Juice Inhibit Ex Vivo Platelet Aggregation in Human Volunteers”, J. Am. Coll. Card., 29(2) Supplement A:226A (1997) (Abstract 767-3). |
Folts et al., “Platelet Inhibitory Effect of Feeding Grape Juice But Not Orange or Grapefruit Juice for Seven Days in Monkeys”, J. Am. Coll. Card., 29(2) Supplement A:303A (1997) (Abstract 1006-156). |
Folts, J.D., “Flavonoids In Tea But Not Coffee Given By Gastric Tube Inhibit In Vivo Platelet Activity and Thrombus Formation in Stenosed Dog Coronary Arteries”, FASEB J., 10(3):A793 (1996). |
Folts et al., “Grape Juice But Not Orange or Grapefruit Juice Significantly Inhibits In Vivo Platelet Activity and Thrombosis in Stenosed Canine Coronary Arteries”, J. Am. Coll. Card., 29(2) Supp. A:180A (734-5). |
Folts, J.D., “Gastric Administration of a Commercial Flavonoid Dietary Supplement Inhibits In Vivo Platelet Activity and Cyclic Flow Reductions in Stenosed Monkey Carotic Arteries”, Circulation, 92(8) Supp I-489, No. 2336 (1995). |
Slane et al., “Platelet Inhibition in Stenosed Canine Arteries by Quercetin and Rutin, Polyphenolic Flavonoids Found in Red Wine”, Clinical Research, 42(2):162A (1994) (Abstract 162A). |
Beretz et al., “Role of cyclic AMP in the inhibition of human platelet aggregation by quercetin, a flavonoid that potentiates the effect of prostacylcin,” Biochem. Pharmacol., 1982, 31(22):3597-3600 (abstract only). |
Goker et al., “Synthesis and inhibitory activities on platelet aggregation of some flavonoid analogues,” Arzneimittelforschung, 1995, 45(2):150-155 (abstract only). |
Hertog et al., “Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study,” Lancet, 1993, 342(8878):1007-1011 (abstract only). |
Hladovec, “Antithrombotic effects of some flavonoids alone and combined with acetylsalicylic acid,” Arzneimittelforschung, 1977, 27(10):1989-1992 (abstract only). |
Huang et al., “Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell,” Eur. J. Pharmacol., 1994, 251(1):91-93 (abstract only). |
Jahromi and Ray, “Antihyperlipidemic effect of flavonoids from Pterocarpus marsupium,” J. Nat. Prod., 1993, 56(7):989-994 (abstract only). |
Keli et al., “Dietary flavonoids, antioxidant vitamins, and incidence of stroke: the Zutphen study,” Arch. Intern. Med., 1996, 156(6):637-642 (abstract only). |
Knekt et al., “Flavonoid intake and coronary mortality in Finland: a cohort study,” BMJ, 1996, 312(7029):478-481 (abstract only). |
Littlewood et al., “Red wine contains a potent inhibitor of phenolsulphotransferase,” Br. J. Clin. Pharmacol., 1985, 19(2):275-278 (abstract only). |
Monforte et al., “Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat,” Farmaco, 1995, 50(9):595-599 (abstract only). |
Robak et al., “On the mechanism of antiaggregatory effect of myricetin,” Pol. J. Pharmacol. Pharm., 1988, 40(3):337-340 (abstract only). |
Smith et al., “The neuroprotective properties of the Ginkgo biloba leaf: a review of the possible relationship to platelet-activating factor (PAF),” J. Ethnopharmacol., 996, 50(3):131-139 (abstract only). |
Taussig and Batkin, “Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update,” J. Ethnopharmacol., 1988, 22(2):191-203 (abstract only). |
Vellini et al., “Possible involvement of eicosanoids in the pharmacological action of bromelain,” Arzneimittelforschung, 1986, 36(1):110-112 (abstract only). |