Claims
- 1. A compound of the formula: ##STR5## wherein X is hydrogen or fluorine and n is 2 or 3; or its pharmaceutically acceptable salt.
- 2. The compound of claim 1, wherein n is 2.
- 3. The compound of claim 1, wherein n is 3.
- 4. The compound of claim 1, wherein X is hydrogen.
- 5. The compound of claim 1, wherein X is fluorine.
- 6. An antihypertensive, coronary or peripheral vasodilator composition comprising
- (a) an antihypertensive, coronary or peripheral vasodilator effective amount of the compound of claim 1; and
- (b) a pharmaceutically acceptable diluent or carrier.
- 7. A method of treating hypertension in a subject in need of such treatment comprising administering to the subject an antihypertensive effective amount of the compound of claim 1 to produce such effect.
- 8. A method of producing coronary vasodilation in a patient in need of such treatment comprising administering to the patinent a coronary vasodilating effective amount of the compound of claim 1 to produce such effect.
- 9. A method of producing peripheral vasodilation in a patient in need of such treatment comprising administering to the patient a peripheral vasodilating effective amount of the compound of claim 1 to produce such effect.
Priority Claims (2)
Number |
Date |
Country |
Kind |
58-177710 |
Sep 1983 |
JPX |
|
59-163649 |
Aug 1984 |
JPX |
|
Parent Case Info
This is a continuation-in-part of U.S. patent application No. 654,473 filed 9/26/84 now U.S. Pat. No. 4,576,934 issued 3/18/86.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4423052 |
Araki et al. |
Dec 1983 |
|
4576934 |
Seto et al. |
Mar 1986 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
150040 |
Oct 1985 |
EPX |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
654473 |
Sep 1984 |
|