Claims
- 1. A dihydrodropyridine derivative represented by the following formula (I) ##STR143## wherein R.sup.1 represents a lower alkyl group; a lower alkyl group substituted by substituents selected from the group consisting of lower alkoxy, lower cycloalkyl, N-methyl-N-benzylamino, and cyano; a lower alkenyl group; or a 3,4-dihydro-2H-benzo[b]pyran-4-yl group
- R.sup.1 and R.sup.3, which may or may not be the same, independently represent a lower alkyl group or an amino group
- X represents a phenyl group substituted by one or more substituents selected from the group consisting of halogen, lower alkyl, lower alkoxy, halo-lower alkyl, halo-lower alkoxy, nitro, and cyano; and a naphthyl group
- Y represents a 3,4-dihydro-2H-benzo[b]pyran-4-yl group; a 3,4-dihydro-2H-benzo[b]pyran-4-yl group substituted by one or more substituents selected form the group consisting of lower alkyl, lower alkoxy, halogen, and cyano; or a salt thereof,
- with the proviso that when R.sup.1 and Y are the same, X is a nitro substituted phenyl group.
- 2. A therapeutic agent having antihypertensive action comprising an effective amount of dihydropyridine compound or salt thereof according to claim 1 and a pharmaceutically acceptable carrier.
- 3. A method for lowering blood pressure comprising administering a therapeutically effective amount of a dihydropyridine compound or salt thereof according to claim 1 to a host.
Priority Claims (1)
Number |
Date |
Country |
Kind |
2-117129 |
May 1990 |
JPX |
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Parent Case Info
This is a continuation of application Ser. No. 07/696,704, filed on May 7, 1991 now U.S. Pat. No. 5,208,245, issued May 4, 1993.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
4532248 |
Franckowiak et al. |
Jul 1985 |
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Non-Patent Literature Citations (3)
Entry |
Merck Index pp. 1047-1048. |
Burger Medicinal Chemistry 2nd Edition pp. 565-601. |
Thomas Jour. of Cardiovascular Pharmac. 6:1170-1176. |
Continuations (1)
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Number |
Date |
Country |
Parent |
696704 |
May 1991 |
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