Direct sampling time resolved detector

Information

  • Research Project
  • 7404366
  • ApplicationId
    7404366
  • Core Project Number
    R43GM083520
  • Full Project Number
    1R43GM083520-01
  • Serial Number
    83520
  • FOA Number
    PA-07-80
  • Sub Project Id
  • Project Start Date
    8/15/2008 - 16 years ago
  • Project End Date
    1/14/2009 - 15 years ago
  • Program Officer Name
    EDMONDS, CHARLES G.
  • Budget Start Date
    8/15/2008 - 16 years ago
  • Budget End Date
    1/14/2009 - 15 years ago
  • Fiscal Year
    2008
  • Support Year
    1
  • Suffix
  • Award Notice Date
    8/4/2008 - 16 years ago
Organizations

Direct sampling time resolved detector

[unreadable] DESCRIPTION (provided by applicant): The proposal describes the development of a novel method for frequency domain time resolved measurements. Application areas include fluorescence microscopy, fluorescence spectroscopy, and photon migration. The proposal is a hybrid approach that combines the sensitivity of time domain methods with the speed and dynamic range of the frequency domain. It has unqualified superiority over all current frequency domain fluorescence and photon migration techniques and rivals Time Correlated Single Photon Counting in sensitivity and signal to noise at low light levels while still be able to process high photon count rates. It will benefit a broad range of disciplines, including fluorescence lifetime imaging, fluorescence resonance energy transfer, photon migration, high throughput screening, and flow cytometry. This proposal will have broad impact in a range of biomedical applications from cancer biology, pharmaceutical development, cell biology, tissue imaging, and noninvasive diagnosis. This proposal describes the development of a new time resolved detection method which is significantly more sensitive and widely applicable than previous approaches. It will help areas such as neonatal care, stroke diagnosis, the study of protein dynamics, drug development and cancer diagnosis. [unreadable] [unreadable] [unreadable]

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R43
  • Administering IC
    GM
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    144929
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    859
  • Ed Inst. Type
  • Funding ICs
    NIGMS:144929\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    TISSUEVISION, INC.
  • Organization Department
  • Organization DUNS
    606771918
  • Organization City
    SOMERVILLE
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    02143
  • Organization District
    UNITED STATES