DIRECTIONAL &ISOTROPIC DIFFUSING TIPS FOR LASER THERAPY

Information

• Research Project
• 3493368

• ApplicationId

  3493368

• Core Project Number

  R43CA060225

• Full Project Number

  1R43CA060225-01A1

• Serial Number

  60225

• FOA Number

• Sub Project Id

• Project Start Date

  2/1/1994 - 32 years ago

• Project End Date

  7/31/1994 - 31 years ago

• Program Officer Name

• Budget Start Date

  2/1/1994 - 32 years ago

• Budget End Date

  7/31/1994 - 31 years ago

• Fiscal Year

  1994

• Support Year

  1

• Suffix

  A1

• Award Notice Date

  1/21/1994 - 32 years ago

Organizations

• CardioFocus, Inc.

New lasers, delivery systems, and photo-sensitizers have broadened horizons in the field of photo-medicine. The tissue's response is highly influenced by its optical properties as well as the geometry of the incident beam. Sometimes modification of the profile of the beam to match the volume of tissue involvement during procedure such as photodynamic and photothermal therapy is desired. Recently interest has developed in fiberoptics for contact surgery and uniform irradiation of tissue during photodynamic therapy. More recently, side emitting tips have been developed for directional irradiation during photothermal therapy. These tips are designed to reflect the laser beam at a 90 degree angle. If a large surface of tissue needs to be irradiated, one must position the tip with multiple laser exposure, aimed only at the untreated areas. Other diffusing tips have not been optimized for the delivery of tens of watts needed for coagulating large volumes. REM seeks to further develop a family of diffusing tips for directional and non-directional, isotropic distribution of laser light.It is proposed to optimize diffusing tips at 630 nm for PDT therapy, 800 and 940 nm light from laser diodes, and l.06um for photocoagulation therapy. These tips will be characterized in air, phantom media, and tissue samples to evaluate and optimize their performance.

IC Name

• Activity

  R43

• Administering IC

  CA

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  395

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  ZRG7

• Study Section Name

• Organization Name

  CARDIOFOCUS, INC.

• Organization Department

• Organization DUNS

• Organization City

  MARLBOROUGH

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  01752

• Organization District

  UNITED STATES