The illustrative embodiments of the invention relate generally to a pump for fluid and, more specifically, to a pump having two cavities in which each pumping cavity is a substantially disc-shaped, cylindrical cavity having substantially circular end walls and a side wall and which operates via acoustic resonance of fluid within the cavity. More specifically, the illustrative embodiments of the invention relate to a pump in which the two pump cavities each have a different valve structure to provide different fluid dynamic capabilities.
It is known to use acoustic resonance to achieve fluid pumping from defined inlets and outlets. This can be achieved using a long cylindrical cavity with an acoustic driver at one end, which drives a longitudinal acoustic standing wave. In such a cylindrical cavity, the acoustic pressure wave has limited amplitude. Varying cross-section cavities, such as cone, horn-cone, and bulb shaped cavities have been used to achieve higher amplitude pressure oscillations, thereby significantly increasing the pumping effect. In such higher amplitude waves, non-linear mechanisms that result in energy dissipation are suppressed by careful cavity design. However, high amplitude acoustic resonance has not been employed within disc-shaped cavities in which radial pressure oscillations are excited until recently. International Patent Application No. PCT/GB2006/001487, published as WO 2006/111775 (the '487 Application), discloses a pump having a substantially disc-shaped cavity with a high aspect ratio, i.e., the ratio of the radius of the cavity to the height of the cavity.
The pump described in the '487 application is further developed in related patent applications PCT/GB2009/050245, PCT/GB2009/050613, PCT/GB2009/050614, PCT/GB2009/050615, and PCT/GB2011/050141. These applications and the '487 Application are included herein by reference.
It is important to note that the pump described in the '487 application and the related applications listed above operates on a different physical principle to the majority of pumps described in the prior art. In particular, many pumps known in the art are displacement pumps, i.e. pumps in which the volume of the pumping chamber is made smaller in order to compress and expel fluids through an outlet valve and is increased in size so as to draw fluid through an inlet valve. An example of such a pump is described in DE4422743 (“Gerlach”), and further examples of displacement pumps may be found in US2004000843, WO2005001287, DE19539020, and U.S. Pat. No. 6,203,291.
By contrast, the '487 application describes a pump that applies the principle of acoustic resonance to motivate fluid through a cavity of the pump. In the operation of such a pump, pressure oscillations within the pump cavity compress fluid within one part of the cavity while expanding fluid in another part of the cavity. In contrast to the more conventional displacement pump, an acoustic resonance pump does not change the volume of the pump cavity in order to achieve pumping operation. Instead, the acoustic resonance pump's design is adapted to efficiently create, maintain, and rectify the acoustic pressure oscillations within the cavity.
Turning now to the design and operation of an acoustic resonance pump in greater detail, the '487 Application describes a pump having a substantially cylindrical cavity. The cylindrical cavity comprises a side wall closed at each end by end walls, one or more of which is a driven end wall. The pump also comprises an actuator that causes an oscillatory motion of the driven end wall (i.e., displacement oscillations) in a direction substantially perpendicular to the end wall or substantially parallel to the longitudinal axis of the cylindrical cavity. These displacement oscillations may be referred to hereinafter as axial oscillations of the driven end wall. The axial oscillations of the driven end wall generate substantially proportional pressure oscillations of fluid within the cavity. The pressure oscillations create a radial pressure distribution approximating that of a Bessel function of the first kind as described in the '487 Application. Such oscillations are referred to hereinafter as radial oscillations of the fluid pressure within the cavity.
The pump of the '487 application has one or more valves for controlling the flow of fluid through the pump. The valves are capable of operating at high frequencies, as it is preferable to operate the pump at frequencies beyond the range of human hearing. Such a valve is described in International Patent Application No. PCT/GB2009/050614.
The driven end wall is mounted to the side wall of the pump at an interface, and the efficiency of the pump is generally dependent upon this interface. It is desirable to maintain the efficiency of such a pump by structuring the interface so that it does not decrease or dampen the motion of the driven end wall, thereby mitigating a reduction in the amplitude of the fluid pressure oscillations within the cavity. Patent application PCT/GB2009/050613 (the '613 Application, incorporated by reference herein) discloses a pump wherein an actuator forms a portion of the driven end wall, and an isolator functions as the interface between actuator and the side wall. The isolator provides an interface that reduces damping of the motion of the driven end wall. Illustrative embodiments of isolators are shown in the figures of the '613 Application.
The pump of the '613 Application comprises a pump body having a substantially cylindrical shape defining a cavity formed by a side wall closed at both ends by substantially circular end walls. At least one of the end walls is a driven end wall having a central portion and a peripheral portion adjacent the side wall. The cavity contains a fluid when in use. The pump further comprises an actuator operatively associated with the central portion of the driven end wall to cause an oscillatory motion of the driven end wall in a direction substantially perpendicular thereto. The pump further comprises an isolator operatively associated with the peripheral portion of the driven end wall to reduce dampening of the displacement oscillations caused by the end wall's connection to the side wall of the cavity. The pump further comprises a first aperture disposed at about the center of one of the end walls, and a second aperture disposed at another location in the pump body, whereby the displacement oscillations generate radial oscillations of fluid pressure within the cavity of the pump body causing fluid flow through the apertures.
A two-cavity disc pump is disclosed wherein each cavity is pneumatically isolated from the other so that each cavity may have a different valve configuration to provide different fluid dynamic capabilities. More specifically, a two-cavity disc pump having a single valve in one cavity and a bidirectional valve in the other cavity is disclosed that is capable of providing both high pressure and high flow rates.
One embodiment of such a pump has a pump body having pump walls substantially cylindrical in shape and having a side wall closed by two end walls for containing a fluid. The pump further comprises an actuator disposed between the two end walls and functioning as a first portion of a common end wall that forms a first cavity and a second cavity. The actuator is operatively associated with a central portion of the common end walls and adapted to cause an oscillatory motion of the common end walls thereby generating radial pressure oscillations of the fluid within both the first cavity and the second cavity.
The pump further comprises an isolator extending from the periphery of the actuator to the side wall as a second portion of the common wall that flexibly supports the actuator that separates the first cavity from the second cavity. A first aperture is disposed at a location in the end wall associated with the first cavity, and a second aperture is disposed at another location in the end wall associated with the first cavity. A first valve is disposed in either one of the first and second apertures to enable the fluid to flow through the first cavity in one direction. A third aperture is disposed at a location in the end wall associated with the second cavity with a bidirectional valve disposed therein to enable fluid to flow through the second cavity in both directions.
Other objects, features, and advantages of the illustrative embodiments are disclosed herein and will become apparent with reference to the drawings and detailed description that follow.
In the following detailed description of several illustrative embodiments, reference is made to the accompanying drawings that form a part hereof, and in which is shown by way of illustration specific embodiments in which the invention may be practiced. These embodiments are described in sufficient detail to enable those skilled in the art to practice the invention, and it is understood that other embodiments may be utilized and that logical structural, mechanical, electrical, and chemical changes may be made without departing from the spirit or scope of the invention. To avoid detail not necessary to enable those skilled in the art to practice the embodiments described herein, the description may omit certain information known to those skilled in the art. The following detailed description is, therefore, not to be taken in a limiting sense, and the scope of the illustrative embodiments are defined only by the appended claims.
The present disclosure includes several possibilities for improving the functionality of an acoustic resonance pump. In operation, the illustrative embodiment of a single-cavity pump shown in FIG. 1A of the '613 Application may generate a net pressure difference across its actuator. The net pressure difference puts stress on the bond between the isolator and the pump body and on the bond between the isolator and the actuator component. It is possible that these stresses may lead to failure of one or more of these bonds, and it is desirable that the bonds should be strong in order to ensure that the pump delivers a long operational lifetime.
Further, in order to operate, the single-cavity pump shown in FIG. 1A of the '613 Application includes a robust electrical connection to the pump's actuator. The robust electrical connection may be achieved by, for example, including soldered wires or spring contacts that may be conveniently attached to the side of the actuator facing away from the pump cavity. However, as disclosed in the '417 Application, a resonant acoustic pump of this kind may also be designed such that two pump cavities are driven by a common driven end wall. A two-cavity pump may deliver increased flow and/or pressure when compared with a single-cavity design, and may deliver increased space, power, or cost efficiency. However, in a two-cavity pump it becomes difficult to make electrical contact to the actuator using conventional means without disrupting the acoustic resonance in at least one of the two pump cavities and/or mechanically dampening the motion of the actuator. For example, soldered wires or spring contacts may disrupt the acoustic resonance of the cavity in which they are present.
Therefore, for reasons of pump lifetime and performance, a pump construction that achieves a strong bond between the actuator and the isolator, and that facilitates robust electrical connection to the actuator without adversely affecting the resonance of either of the cavities of a two-cavity pump is desirable.
Referring to
The internal surfaces of the cylindrical wall 11, the base 12, the end plate 41, and the isolator 30 form a first cavity 16 within the pump 10 wherein the first cavity 16 comprises a side wall 15 closed at both ends by end walls 13 and 14. The end wall 13 is the internal surface of the base 12, and the side wall 15 is the inside surface of the cylindrical wall 11. The end wall 14 comprises a central portion corresponding to a surface of the end plate 41 and a peripheral portion corresponding to a first surface of the isolator 30. Although the first cavity 16 is substantially circular in shape, the first cavity 16 may also be elliptical or another shape. The internal surfaces of the cylindrical wall 18, the base 19, the piezoelectric disc 42, and the isolator 30 form a second cavity 23 within the pump 10 wherein the second cavity 23 comprises a side wall 22 closed at both ends by end walls 20 and 21. The end wall 20 is the internal surface of the base 19, and the side wall 22 is the inside surface of the cylindrical wall 18. The end wall 21 comprises a central portion corresponding to the inside surface of the piezoelectric disc 42 and a peripheral portion corresponding to a second surface of the isolator 30. Although the second cavity 23 is substantially circular in shape, the second cavity 23 may also be elliptical or another shape. The cylindrical walls 11, 18, and the bases 12, 19 of the first and second pump bodies may be formed from a suitable rigid material including, without limitation, metal, ceramic, glass, or plastic.
The piezoelectric disc 42 is operatively connected to the end plate 41 to form an actuator 40. In turn, the actuator 40 is operatively associated with the central portion of the end walls 14 and 21. The piezoelectric disc 42 may be formed of a piezoelectric material or another electrically active material such as, for example, an electrostrictive or magnetostrictive material. The end plate 41 preferably possesses a bending stiffness similar to the piezoelectric disc 42 and may be formed of an electrically inactive material such as a metal or ceramic. When the piezoelectric disc 42 is excited by an oscillating electrical current, the piezoelectric disc 42 attempts to expand and contract in a radial direction relative to the longitudinal axis of the cavities 16, 23 causing the actuator 40 to bend. The bending of the actuator 40 induces an axial deflection of the end walls 14, 21 in a direction substantially perpendicular to the end walls 14, 21. The end plate 41 may also be formed from an electrically active material such as, for example, a piezoelectric, magnetostrictive, or electrostrictive material.
The pump 10 further comprises at least two apertures extending from the first cavity 16 to the outside of the pump 10, wherein at least a first one of the apertures contains a valve to control the flow of fluid through the aperture. The aperture containing a valve may be located at a position in the cavity 16 where the actuator 40 generates a pressure differential as described below in more detail. One embodiment of the pump 10 comprises an aperture with a valve located at approximately the center of the end wall 13. The pump 10 comprises a primary aperture 25 extending from the cavity 16 through the base 12 of the pump body at about the center of the end wall 13 and containing a valve 35. The valve 35 is mounted within the primary aperture 25 and permits the flow of fluid in one direction as indicated by the arrow so that it functions as a fluid inlet for the pump 10. The term fluid inlet may also refer to an outlet of reduced pressure. The second aperture 27 may be located at a position within the cavity 11 other than the location of the aperture 25 having the valve 35. In one embodiment of the pump 10, the second aperture 27 is disposed between the center of the end wall 13 and the side wall 15. The embodiment of the pump 10 comprises two secondary apertures 27 extending from the cavity 11 through the base 12 that are disposed between the center of the end wall 13 and the side wall 15.
The pump 10 further comprises at least two apertures extending from the cavity 23 to the outside of the pump 10, wherein at least a first one of the apertures may contain a valve to control the flow of fluid through the aperture. The aperture containing a valve may be located at a position in the cavity 23 where the actuator 40 generates a pressure differential as described below in more detail. One embodiment of the pump 10 comprises an aperture with a valve located at approximately the center of the end wall 20. The pump 10 comprises a primary aperture 26 extending from the cavity 23 through the base 19 of the pump body at about the center of the end wall 20 and containing a valve 36. The valve 36 is mounted within the primary aperture 26 and permits the flow of fluid in one direction as indicated by the arrow so that it functions as a fluid inlet for the pump 10. The term fluid inlet may also refer to an outlet of reduced pressure. The second aperture 28 may be located at a position within the cavity 23 other than the location of the aperture 26 having the valve 36. In one embodiment of the pump 10, the second aperture 28 is disposed between the center of the end wall 20 and the side wall 22. The embodiment of the pump 10 comprises two secondary apertures 28 extending from the cavity 23 through the base 19 that are disposed between the center of the end wall 20 and the side wall 22.
Although valves are not shown in the secondary apertures 27, 28 in the embodiment of the pump 10 shown in
The valves 35 and 36 allow fluid to flow through in substantially one direction as described above. The valves 35 and 36 may be a ball valve, a diaphragm valve, a swing valve, a duck-bill valve, a clapper valve, a lift valve, or another type of check valve or valve that allows fluid to flow substantially in only one direction. Some valve types may regulate fluid flow by switching between an open and closed position. For such valves to operate at the high frequencies generated by the actuator 40, the valves 35 and 36 must have an extremely fast response time such that they are able to open and close on a timescale significantly shorter than the timescale of the pressure variation. One embodiment of the valves 35 and 36 achieves this by employing an extremely light flap valve which has low inertia and consequently is able to move rapidly in response to changes in relative pressure across the valve structure.
Referring more specifically to
The operation of the flap valve 50 is a function of the change in direction of the differential pressure (ΔP) of the fluid across the flap valve 50. In
Turning now to the detailed construction of the combined actuator and isolator,
The isolator 300 is comprised of a flexible, electrically non-conductive core 303 with conductive electrodes on its upper and lower surfaces. The upper surface of the isolator 300 includes a first isolator electrode 301 and the lower surface of the isolator 300 includes a second isolator electrode 302. The first isolator electrode 301 connects with the wrap electrode 423 and thereby with the first actuator electrode 421 of the piezoelectric disc 42. The second isolator electrode 302 connects with the end plate 41 and thereby with the second actuator electrode 422 of the piezoelectric disc 42. In this case, the end plate 41 should be formed from an electrically conductive material. In an exemplary embodiment, the actuator 40 comprises a steel end plate 41 of between about 5 mm and about 20 mm radius and between about 0.1 mm and about 3 mm thickness bonded to a piezoceramic piezoelectric disc 42 of similar dimensions. The isolator core 303 is a formed from polyimide with a thickness of between about 5 microns and about 200 microns, The first and second isolator electrodes 301, 302 are formed from copper layers having a thickness of between about 3 microns and about 50 microns. In the exemplary embodiment, the actuator 40 comprises a steel end plate 41 of about 10 mm radius and about 0.5 mm thickness bonded to a piezoceramic disc 42 of similar dimensions. The isolator core 303 is formed from polyimide with a thickness of about 25 microns. The first and second isolator electrodes 301, 302 are formed from copper having a thickness of about 9 microns. Further capping layers of polyimide (not shown) may be applied selectively to the isolator 300 to insulate the first and second isolator electrodes 301, 302 and to provide robustness.
In one embodiment, the electrode layer that forms the first isolator electrode 301 is a copper layer formed adjacent a polyimide layer, as described above. The second isolator electrode 302 may be formed from a second electrode layer that is adjacent the side of the polyimide layer that opposes the first electrode layer. In this embodiment, the first isolator electrode 301 is patterned to leave the windows 311 in the electrode layer that forms the first isolator electrode 301. The windows 311 provide an area where the isolator 300 flexes more freely between the outside edge of the actuator 40 and the inside edge of the pump bases 11 and 18. These windows 311 locally reduce the stiffness of the isolator 300, enabling the isolator 300 to bend more readily, thereby reducing a damping effect that the electrode layer might otherwise have on the motion of the actuator 40. The inner ring portion 313 of the first isolator electrode 301 enables connection to the wrap electrode 423 of the piezoelectric disc 42. The inner ring portion 313 is connected to the outer ring portion 314 by four spoke members 312. A further part 315 of the electrode 301 extends along the tail 310 to facilitate connection of the pump 10 to a drive circuit. The second isolator electrode 302 may be similarly configured.
In one non-limiting example, the diameter of the piezoelectric disc 42 and the end plate 41 may be 1-2 mm less than the diameter of the cavities 16 and 23 such that the isolator 30 spans the peripheral portion of the end walls 14 and 21. The peripheral portion may be an annular gap of about 0.5 mm to about 1.0 mm between the edge of the actuator 40 and the side walls 15 and 22 of the cavities 16 and 23, respectively. Generally, the annular width of this gap should be relatively small compared to the cavity radius (r) such that the diameter of the actuator 40 is close to the diameter of the cavities 16, 23 so that the diameter of an annular displacement node 47 (not shown) is approximately equal to the diameter of an annular pressure node 57 (not shown), while being large enough to facilitate and not restrict the vibrations of the actuator 40. The annular displacement node 47 and the annular pressure node 57 are described in more detail with respect to
Referring now to
With reference to
As indicated above, the operation of the valve 50 is a function of the change in direction of the differential pressure (ΔP) of the fluid across the valve 50. The differential pressure (ΔP) is assumed to be substantially uniform across the entire surface of the retention plate 52. This is assumed because (i) the diameter of the retention plate 52 is small relative to the wavelength of the pressure oscillations in the cavities 16 and 23, and (ii) the valve 50 is located near the center of the cavities where the amplitude of the positive central pressure anti-node 58 is relatively constant. Referring to
The dimensions of the pumps described herein should preferably satisfy certain inequalities with respect to the relationship between the height (h) of the cavities 16 and 23 and the radius (r) of the cavities 16 and 23. The radius (r) is the distance from the longitudinal axis of the cavity to its respective side wall 15, 22. These equations are as follows:
r/h>1.2; and
h2/r>4×10−10 meters.
In one exemplary embodiment, the ratio of the cavity radius to the cavity height (r/h) is between about 10 and about 50 when the fluid within the cavities 16, 23 is a gas. In this example, the volume of the cavities 16, 23 may be less than about 10 ml. Additionally, the ratio of h2/r is preferably within a range between about 10−3 and about 10−6 meters where the working fluid is a gas as opposed to a liquid.
In one exemplary embodiment, the secondary apertures 27, 28 (
Additionally, the pumps disclosed herein should preferably satisfy the following inequality relating the cavity radius (r) and operating frequency (f), which is the frequency at which the actuator 40 vibrates to generate the axial displacement of the end walls 14, 21. The inequality equation is as follows:
The speed of sound in the working fluid within the cavities 16, 23, (c) may range between a slow speed (cs) of about 115 m/s and a fast speed (cf) equal to about 1,970 m/s as expressed in the equation above, and k0 is a constant (k0=3.83). The frequency of the oscillatory motion of the actuator 40 is preferably about equal to the lowest resonant frequency of radial pressure oscillations in the cavities 16, 23, but may be within 20% therefrom. The lowest resonant frequency of radial pressure oscillations in the cavities 16, 23 is preferably greater than 500 Hz.
One application, for example, is using a hybrid pump for wound therapy. Hybrid pump 90 is useful for providing negative pressure to the manifold used in a dressing for wound therapy where the dressing is positioned adjacent the wound and covered by a drape that seals the negative pressure within the wound site. When the primary apertures 925 and 926 are both at ambient pressure and the actuator 40 begins vibrating and generating pressure oscillations within the cavities 16 and 23 as described above, air begins flowing alternatively through the valves 935 and 936 causing air to flow out of the secondary apertures 927 and 928 such that the hybrid pump 90 begins operating in a “free-flow” mode. As the pressure at the primary apertures 925 and 926 increases from ambient pressure to a gradually increasing negative pressure, the hybrid pump 90 ultimately reaches a maximum target pressure at which time the air flow through the two cavities 16 and 23 is negligible, i.e., the hybrid pump 90 is in a “stall condition” with no air flow. Increased flow rates from the cavity 16 of the hybrid pump 90 are needed for two therapy conditions. First, high flow rates are needed to initiate the negative pressure therapy in the free-flow mode so that the dressing is evacuated quickly, causing the drape to create a good seal over the wound site and maintain the negative pressure at the wound site. Second, after the pressure at the primary apertures 925 and 926 reach the maximum target pressure such that the hybrid pump 90 is in the stall condition, high flow rates are again needed maintain the target pressure in the event that the drape or dressing develops a leak to weaken the seal.
Referring now to
Referring now to
As shown above in
Referring to
It should be apparent from the foregoing that the hybrid pump 90 is also useful for other negative pressure applications and positive pressure applications that require different fluid dynamic capabilities such as, for example, higher flow rates to quickly achieve and maintain a target pressure.
It should also be apparent from the foregoing that an invention having significant advantages has been provided. While the invention is shown in only a few of its forms, it is not just limited to those shown but is susceptible to various changes and modifications without parting from the spirit of the invention.
This application is a continuation of U.S. patent application Ser. No. 14/813,977, filed Jul. 30, 2015, which is a continuation of U.S. patent application Ser. No. 13/782,665, filed on Mar. 1, 2013, which claims priority to U.S. Provisional Patent Application No. 61/607,904, entitled “Disc Pump with Advanced Actuator,” filed Mar. 7, 2012, by Locke et al., which is incorporated herein by reference for all purposes.
Number | Name | Date | Kind |
---|---|---|---|
1355846 | Rannells | Oct 1920 | A |
1633772 | Clapp | Jun 1927 | A |
2547758 | Keeling | Apr 1951 | A |
2632443 | Lesher | Mar 1953 | A |
2682873 | Evans et al. | Jul 1954 | A |
2910763 | Lauterbach | Nov 1959 | A |
2969057 | Simmons | Jan 1961 | A |
3029743 | Johns | Apr 1962 | A |
3066672 | Crosby, Jr. et al. | Dec 1962 | A |
3314600 | Hadley | Apr 1967 | A |
3367332 | Groves | Feb 1968 | A |
3520300 | Flower, Jr. | Jul 1970 | A |
3568675 | Harvey | Mar 1971 | A |
3606592 | Madurski et al. | Sep 1971 | A |
3648692 | Wheeler | Mar 1972 | A |
3682180 | McFarlane | Aug 1972 | A |
3826254 | Mellor | Jul 1974 | A |
4080970 | Miller | Mar 1978 | A |
4096853 | Weigand | Jun 1978 | A |
4137020 | Ito | Jan 1979 | A |
4139004 | Gonzalez, Jr. | Feb 1979 | A |
4164238 | Riedel | Aug 1979 | A |
4165748 | Johnson | Aug 1979 | A |
4184510 | Murry et al. | Jan 1980 | A |
4233969 | Lock et al. | Nov 1980 | A |
4245630 | Lloyd et al. | Jan 1981 | A |
4256109 | Nichols | Mar 1981 | A |
4261363 | Russo | Apr 1981 | A |
4275721 | Olson | Jun 1981 | A |
4284079 | Adair | Aug 1981 | A |
4297995 | Golub | Nov 1981 | A |
4333468 | Geist | Jun 1982 | A |
4373519 | Errede et al. | Feb 1983 | A |
4382441 | Svedman | May 1983 | A |
4392853 | Muto | Jul 1983 | A |
4392858 | George et al. | Jul 1983 | A |
4419097 | Rowland | Dec 1983 | A |
4437490 | Demers | Mar 1984 | A |
4465485 | Kashmer et al. | Aug 1984 | A |
4475909 | Eisenberg | Oct 1984 | A |
4480638 | Schmid | Nov 1984 | A |
4525166 | Leclerc | Jun 1985 | A |
4525374 | Vaillancourt | Jun 1985 | A |
4540412 | Van Overloop | Sep 1985 | A |
4543100 | Brodsky | Sep 1985 | A |
4548202 | Duncan | Oct 1985 | A |
4551139 | Plaas et al. | Nov 1985 | A |
4569348 | Hasslinger | Feb 1986 | A |
4605399 | Weston et al. | Aug 1986 | A |
4608041 | Nielsen | Aug 1986 | A |
4640688 | Hauser | Feb 1987 | A |
4648807 | Tippetts et al. | Mar 1987 | A |
4655754 | Richmond et al. | Apr 1987 | A |
4664662 | Webster | May 1987 | A |
4710165 | McNeil et al. | Dec 1987 | A |
4733659 | Edenbaum et al. | Mar 1988 | A |
4743232 | Kruger | May 1988 | A |
4758220 | Sundblom et al. | Jul 1988 | A |
4776776 | Jones | Oct 1988 | A |
4787888 | Fox | Nov 1988 | A |
4826494 | Richmond et al. | May 1989 | A |
4838883 | Matsuura | Jun 1989 | A |
4840187 | Brazier | Jun 1989 | A |
4863449 | Therriault et al. | Sep 1989 | A |
4872450 | Austad | Oct 1989 | A |
4878901 | Sachse | Nov 1989 | A |
4897081 | Poirier et al. | Jan 1990 | A |
4906233 | Moriuchi et al. | Mar 1990 | A |
4906240 | Reed et al. | Mar 1990 | A |
4919654 | Kalt | Apr 1990 | A |
4941882 | Ward et al. | Jul 1990 | A |
4953565 | Tachibana et al. | Sep 1990 | A |
4969880 | Zamierowski | Nov 1990 | A |
4985019 | Michelson | Jan 1991 | A |
5037397 | Kalt et al. | Aug 1991 | A |
5086170 | Luheshi et al. | Feb 1992 | A |
5092858 | Benson et al. | Mar 1992 | A |
5100396 | Zamierowski | Mar 1992 | A |
5134994 | Say | Aug 1992 | A |
5149331 | Ferdman et al. | Sep 1992 | A |
5165392 | Small, Jr. | Nov 1992 | A |
5167613 | Karami et al. | Dec 1992 | A |
5176663 | Svedman et al. | Jan 1993 | A |
5215522 | Page et al. | Jun 1993 | A |
5232453 | Plass et al. | Aug 1993 | A |
5261893 | Zamierowski | Nov 1993 | A |
5278100 | Doan et al. | Jan 1994 | A |
5279550 | Habib et al. | Jan 1994 | A |
5298015 | Komatsuzaki et al. | Mar 1994 | A |
5342376 | Ruff | Aug 1994 | A |
5344415 | DeBusk et al. | Sep 1994 | A |
5358494 | Svedman | Oct 1994 | A |
5437622 | Carlon | Aug 1995 | A |
5437651 | Todd et al. | Aug 1995 | A |
5527293 | Zamierowski | Jun 1996 | A |
5549584 | Gross | Aug 1996 | A |
5556375 | Ewall | Sep 1996 | A |
5607388 | Ewall | Mar 1997 | A |
5636643 | Argenta et al. | Jun 1997 | A |
5645081 | Argenta et al. | Jul 1997 | A |
6071267 | Zamierowski | Jun 2000 | A |
6074178 | Bishop et al. | Jun 2000 | A |
6079214 | Bishop | Jun 2000 | A |
6135116 | Vogel et al. | Oct 2000 | A |
6241747 | Ruff | Jun 2001 | B1 |
6287316 | Agarwal et al. | Sep 2001 | B1 |
6345623 | Heaton et al. | Feb 2002 | B1 |
6488643 | Tumey et al. | Dec 2002 | B1 |
6493568 | Bell et al. | Dec 2002 | B1 |
6553998 | Heaton et al. | Apr 2003 | B2 |
6814079 | Heaton et al. | Nov 2004 | B2 |
7846141 | Weston | Dec 2010 | B2 |
8062273 | Weston | Nov 2011 | B2 |
8216198 | Heagle et al. | Jul 2012 | B2 |
8251979 | Malhi | Aug 2012 | B2 |
8257327 | Blott et al. | Sep 2012 | B2 |
8398614 | Blott et al. | Mar 2013 | B2 |
8449509 | Weston | May 2013 | B2 |
8529548 | Blott et al. | Sep 2013 | B2 |
8535296 | Blott et al. | Sep 2013 | B2 |
8551060 | Schuessler et al. | Oct 2013 | B2 |
8568386 | Malhi | Oct 2013 | B2 |
8679081 | Heagle et al. | Mar 2014 | B2 |
8834451 | Blott et al. | Sep 2014 | B2 |
8841820 | Bennett et al. | Sep 2014 | B2 |
8926592 | Blott et al. | Jan 2015 | B2 |
9017302 | Vitaris et al. | Apr 2015 | B2 |
9127665 | Locke | Sep 2015 | B2 |
9198801 | Weston | Dec 2015 | B2 |
9211365 | Weston | Dec 2015 | B2 |
9289542 | Blott et al. | Mar 2016 | B2 |
9797392 | Locke | Oct 2017 | B2 |
10087923 | Campbell | Oct 2018 | B2 |
20020077661 | Saadat | Jun 2002 | A1 |
20020094285 | Paolini et al. | Jul 2002 | A1 |
20020115951 | Norstrem et al. | Aug 2002 | A1 |
20020120185 | Johnson | Aug 2002 | A1 |
20020143286 | Tumey | Oct 2002 | A1 |
20050089415 | Cho et al. | Apr 2005 | A1 |
20070065309 | Nakajima et al. | Mar 2007 | A1 |
20080038125 | Onishi | Feb 2008 | A1 |
20100310398 | Janse Van Rensburg et al. | Dec 2010 | A1 |
20140163491 | Schuessler et al. | Jun 2014 | A1 |
20150080788 | Blott et al. | Mar 2015 | A1 |
Number | Date | Country |
---|---|---|
550575 | Mar 1986 | AU |
745271 | Mar 2002 | AU |
755496 | Dec 2002 | AU |
2005436 | Jun 1990 | CA |
26 40 413 | Mar 1978 | DE |
43 06 478 | Sep 1994 | DE |
29 504 378 | Sep 1995 | DE |
0100148 | Feb 1984 | EP |
0117632 | Sep 1984 | EP |
0161865 | Nov 1985 | EP |
0358302 | Mar 1990 | EP |
1018967 | Jul 2000 | EP |
692578 | Jun 1953 | GB |
1224316 | Mar 1971 | GB |
2 195 255 | Apr 1988 | GB |
2 197 789 | Jun 1988 | GB |
2 220 357 | Jan 1990 | GB |
2 235 877 | Mar 1991 | GB |
2 329 127 | Mar 1999 | GB |
2 333 965 | Aug 1999 | GB |
4129536 | Aug 2008 | JP |
2009264247 | Nov 2009 | JP |
71559 | Apr 2002 | SG |
8002182 | Oct 1980 | WO |
8704626 | Aug 1987 | WO |
90010424 | Sep 1990 | WO |
93009727 | May 1993 | WO |
94020041 | Sep 1994 | WO |
9605873 | Feb 1996 | WO |
9718007 | May 1997 | WO |
9913793 | Mar 1999 | WO |
WO 2004020022 | Mar 2004 | WO |
2006111775 | Oct 2006 | WO |
2010139918 | Dec 2010 | WO |
2010139917 | Dec 2010 | WO |
2011097361 | Aug 2011 | WO |
Entry |
---|
Louis C. Argenta, MD and Michael J. Morykwas, PHD; Vacuum-Assisted Closure: A New Method for Wound Control and Treatment: Clinical Experience; Annals of Plastic Surgery; vol. 38, No. 6, Jun. 1997; pp. 563-576. |
Susan Mendez-Eatmen, RN; “When wounds Won't Heal” RN Jan. 1998, vol. 61 (1); Medical Economics Company, Inc., Montvale, NJ, USA; pp. 20-24. |
Orringer, Jay, et al; “Management of Wounds in Patients with Complex Enterocutaneous Fistulas”; Surgery, Gynecology & Obstetrics, Jul. 1987, vol. 165, pp. 79-80. |
International Search Report for PCT International Application PCT/GB95/01983; dated Nov. 23, 1995. |
PCT International Examination and Search Report, PCT International Application PCT/GB96/02802; dated Jan. 15, 1998 & Apr. 29, 1997. |
PCT Written Opinion, PCT International Application PCT/GB96/02802; dated Sep. 3, 1997. |
Dattilo, Philip P., Jr., et al; “Medical Textiles: Application of an Abosorbable Barbed Bi-directiuonal Surgical Suture”; Journal of Textile and Apparel, Technology and Mangement, vol. 2, Issue 2, Spring 2002, pp. 1-5. |
Kostyuchenok, B.M., et al; “Vacuum Treatment in the Surgical Management of Purulent Wounds”; Vestnik Khirurgi, Sep. 1986, pp. 18-21 and 6 page English translation thereof. |
Davydov, Yu. A., et al; “Vacuum Therapy in the Treatment of Purulent Lactation Mastitis”; Vestnik Khirurgi, May 14, 1986, pp. 66-70, and 9 page English translation thereof. |
Yusupov. Yu.N., et al; “Active Wound Drainage”, Vestnki Khirurgi, vol. 138, Issue 4, 1987, and 7 page English translation thereof. |
Davydov, Yu.A., et al; “Bacteriological and Cytological Assessment of Vacuum Therapy for Purulent Wounds”; Vestnik Khirugi, Oct. 1988, pp: 48-52, and 8 page English translation thereof. |
Davydov, Yu.A., et al; “Concepts for the Clinical-Biological Management of the Wound Process in the Treatment of Purulent Wounds by Means of Vacuum Therapy”; Vestnik Khirurgi, Jul. 7, 1980, pp. 132-136, and 8 page English translation thereof. |
Chariker, Mark E., M.D., et al; “Effective Management of incisional and cutaneous fistulae with closed suction wound drainage”; Contemporary Surgery, vol. 34, Jun. 1989, pp. 59-63. |
Egnell Minor, Instruction Book, First Edition, 300 7502, Feb. 1975, pp. 24. |
Egnell Minor: Addition to the Users Manual Concerning Overflow Protection—Concerns all Egnell Pumps, Feb. 3, 1983, pp. 2. |
Chinn, Steven D. et al.: “Closed Wound Suction Drainage”, The Journal of Foot Surgery, vol. 24, No. 1, 1985, pp. 76-81. |
Arnljots, Björn et al.: “Irrigation Treatment in Split-Thickness Skin Grafting of Intractable Leg Ulcers”, Scand J. Plast Reconstr. Surg., No. 19, 1985, pp. 211-213. |
N.A. Bagautdinov, “Variant of External Vacuum Aspiration in the Treatment of Purulent Diseases of Soft Tissues,” Current Problems in Modern Clinical Surgery: Interdepartmental Collection, edited by V. Ye Volkov et al. (Chuvashia State University, Cheboksary, U.S.S.R. 1986); pp. 94-96 (copy and certified translation). |
G. {hacek over (Z)}ivadinovi?, V. ?uki?, {hacek over (Z)}. Maksimovi?, ?. Radak, and P. Pe{hacek over (s)}ka, “Vacuum Therapy in the Treatment of Peripheral Blood Vessels,” Timok Medical Journal 11 (1986), pp. 161-164 (copy and certified translation). |
F.E. Johnson, “An Improved Technique for Skin Graft Placement Using a Suction Drain,” Surgery, Gynecology, and Obstetrics 159 (1984), pp. 584-585. |
M. Schein, R. Saadia, J.R. Jamieson, and G.A.G. Decker, “The ‘Sandwich Technique’ in the Management of the Open Abdomen,” British Journal of Surgery 73 (1986), pp. 369-370. |
D.E. Tribble, An Improved Sump Drain-Irrigation Device of Simple Construction, Archives of Surgery 105 (1972) pp. 511-513. |
M.J. Morykwas, L.C. Argenta, E.I. Shelton-Brown, and W. McGuirt, “Vacuum-Assisted Closure: A New Method for Wound Control and Treatment: Animal Studies and Basic Foundation,” Annals of Plastic Surgery 38 (1997), pp. 553-562 (Morykwas I). |
Selections from W. Meyer and V. Schmieden, Bier's Hyperemic Treatment in Surgery, Medicine, and the Specialties: A Manual of Its Practical Application, (W.B. Saunders Co., Philadelphia, PA 1909), pp. 17-25, 44-64, 90-96, 167-170, and 210-211. |
V.A. Solovev et al., Guidelines, The Method of Treatment of Immature External Fistulas in the Upper Gastrointestinal Tract, editor-in-chief Prov. V.I. Parahonyak (S.M. Kirov Gorky State Medical Institute, Gorky, U.S.S.R. 1987) (“Solovev Guidelines”). |
V.A. Kuznetsov & N.a. Bagautdinov, “Vacuum and Vacuum-Sorption Treatment of Open Septic Wounds,” in II All-Union Conference on Wounds and Wound Infections: Presentation Abstracts, edited by B.M. Kostyuchenok et al. (Moscow, U.S.S.R. Oct. 28-29, 1986) pp. 91-92 (“Bagautdinov II”). |
V.A. Solovev, Dissertation Abstract, Treatment and Prevention of Suture Failures after Gastric Resection (S.M. Kirov Gorky State Medical Institute, Gorky, U.S.S.R. 1988) (“Solovev Abstract”). |
V.A.C. ® Therapy Clinical Guidelines: A Reference Source for Clinicians; Jul. 2007. |
International Search Report and Written Opinion for corresponding PCT/US2013/028534, dated May 23, 2013. |
James H. Blackburn II, MD et al.: Negative-Pressure Dressings as a Bolster for Skin Grafts; Annals of Plastic Surgery, vol. 40, No. 5, May 1998, pp. 453-457; Lippincott Williams & Wilkins, Inc., Philidelphia, PA, USA. |
John Masters; Reliable, Inexpensive and Simple Suction Dressings'; Letter to the Editor, British Journal of Plastic Surgery, 1998, vol. 51 (3), p. 267; Elsevier Science/The British Association of Plastic Surgeons, UK. |
S.E. Greer, et al. “The Use of Subatmospheric Pressure Dressing Therapy to Close Lymphocutaneous Fistulas of the Groin” British Journal of Plastic Surgery (2000), 53, pp. 484-487. |
George V. Letsou, MD., et al; “Stimulation of Adenylate Cyclase Activity in Cultured Endothelial Cells Subjected to Cyclic Stretch”; Journal of Cardiovascular Surgery, 31, 1990, pp. 634-639. |
PCT International Search Report for PCT International Application PCT/GB98/02713; dated Jan. 8, 1999. |
PCT Written Opinion; PCT International Application PCT/GB98/02713; dated Jun. 8, 1999. |
Svedman, P.: “Irrigation Treatment of Leg Ulcers”, The Lancet, Sep. 3, 1983, pp. 532-534. |
Svedman, P.: “A Dressing Allowing Continuous Treatment of a Biosurface”, IRCS Medical Science: Biomedical Technology, Clinical Medicine, Surgery and Transplantation, vol. 7, 1979, p. 221. |
Svedman, P. et al: “A Dressing System Providing Fluid Supply and Suction Drainage Used for Continuous of Intermittent Irrigation”, Annals of Plastic Surgery, vol. 17, No. 2, Aug. 1986, pp. 125-133. |
K.F. Jeter, T.E. Tintle, and M. Chariker, “Managing Draining Wounds and Fistulae: New and Established Methods,” Chronic Wound Care, edited by D. Krasner (Health Management Publications, Inc., King of Prussia, PA 1990), pp. 240-246. |
A.A. Safronov, Dissertation Abstract, Vacuum Therapy of Trophic Ulcers of the Lower Leg with Simultaneous Autoplasty of the Skin (Central Scientific Research Institute of Traumatology and Orthopedics, Moscow, U.S.S.R. 1967) (copy and certified translation). |
C.E. Tennants, “The Use of Hypermia in the Postoperative Treatment of Lesions of the Extremities and Thorax,” Journal of the American Medical Association 64 (1915), pp. 1548-1549. |
Number | Date | Country | |
---|---|---|---|
20180058439 A1 | Mar 2018 | US |
Number | Date | Country | |
---|---|---|---|
61607904 | Mar 2012 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 14813977 | Jul 2015 | US |
Child | 15711536 | US | |
Parent | 13782665 | Mar 2013 | US |
Child | 14813977 | US |