Claims
- 1. A dispenser for delivering a beneficial drug to a biological environment of use, wherein the dispenser comprises:
- (a) a wall comprising in at least a part a semipermeable composition permeable to the passage of fluid and substantially impermeable to the passage of a beneficial drug, which wall surrounds;
- (b) a pharmaceutically acceptable single-piece capsule;
- (c) means in the capsule for absorbing heat from the biological environment for forming a dispensable composition, which means exhibits storable properties up to 32.degree. C. and becomes at least one of fluid, semisolid and viscous at a temperature of 32.degree. C. to 40.degree. C. thereby providing a dispensable composition;
- (d) a beneficial drug housed in the means for absorbing heat from the biological environment, said drug producing at least one of a local and systemic effect when the dispenser is in operation in the biological environment;
- (e) means in the capsule for urging the means for absorbing heat comprising the beneficial drug from the dispenser, said urging means at least one of a member selected from the group consisting of an expandable acrylate, pyrrolidone, anionic hydrogel, cationic hydrogel, polyelectrolyte, cellulosic, polysaccharide, carboxypolymer, acrylamide, polyalkylene oxide, starch, and vinyl lactam; and,
- (f) at least one orifice in the dispenser for delivering the beneficial drug composition from the dispenser.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a division of U.S. Ser. No. 06/591,824 filed on Mar. 21, 1984, now abandoned.
US Referenced Citations (27)
Divisions (1)
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Number |
Date |
Country |
Parent |
591824 |
Mar 1984 |
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