DNA AMPLIFICATION FOR THE DIAGNOSIS OF GENETIC DISEASE

Information

• Research Project
• 2199516

• ApplicationId

  2199516

• Core Project Number

  R44HD025348

• Full Project Number

  5R44HD025348-03

• Serial Number

  25348

• FOA Number

• Sub Project Id

• Project Start Date

  3/1/1990 - 34 years ago

• Project End Date

  2/29/1992 - 32 years ago

• Program Officer Name

• Budget Start Date

  3/1/1991 - 33 years ago

• Budget End Date

  2/29/1992 - 32 years ago

• Fiscal Year

  1991

• Support Year

  3

• Suffix

• Award Notice Date

  4/15/1991 - 33 years ago

Organizations

• INTEGRATED GENETICS, INC.

This proposal involves the application of in vitro DNA amplification and synthetic DNA probes to the clinical analysis of genetic disease. The first phase of this project analyzed four of the more informative DNA probes linked to cystic fibrosis. Phase II will expand this analysis to additional cystic fibrosis markers, as well as those for Huntington's disease, hemophilia A and B, and Duchenne's muscular dystrophy. We will investigate issues of general technology applicable to disease diagnosis by DNA amplification. Protocols for the specific application of these methods to routine clinical analysis will also be developed. The speed and accuracy of this technique is expected to have significant effects on the clinical determination of the inheritance of genetic disease.

IC Name

• Activity

  R44

• Administering IC

  HD

• Application Type

  5

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  865

• Ed Inst. Type

• Funding ICs

• Funding Mechanism

• Study Section

  SSS

• Study Section Name

• Organization Name

  INTEGRATED GENETICS, INC.

• Organization Department

• Organization DUNS

• Organization City

  FRAMINGHAM

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  01701

• Organization District

  UNITED STATES