Arab et al.--Biological Abstracts report of meeting held Oct. 12-15, 1988, New Orleans, La. (39th annual meeting of Am. Soc. of Human Genetics). |
International Search Report from European Patent Office, mailed May 15, 1990, in PCT/US90/00291 (based on U.S. Appl. Ser. No. 07/420,775 and others). |
Am. J. Human Genetics (Suppl.), vol. 43, No. 3, Sep. 1988, H. Arab et al.: "Maternal serum beta human chorionic gonadotropin . . . ". |
Prenatal Diagnosis, vol. 7, 1987, Mark H. Bogart et al. "Abnormal maternal serum chorionic . . . ". |
British Med. Journal, vol. 297, Oct. 1988, N. J. Wald et al.: "Maternal serum screening . . . ". |
Patent Abstracts of Japan, vol. 3, No. 143, C 66, abstract of JP 54-126723, publ. Feb. 10, 1979 Teikoku Zoki Seiy Aku K.K. |
American Journal of Obstetrics and Gynecology, vol. 48, No. 7, 1984, I. R. Merkatz et al.: "An association between low maternal serum . . . ". |
Ann. Endocrinol. (Paris) vol. 45(4-5), pp. 269-280, 1984, Gaspard, U. et al., "HCG and its Subunits in Normal and Pathological Pregnancies". |
Acta Endocrinol.; 100(1), pp. 109-113, 1982, L'Hermite-Baleriaux, M. et al., "Alteration of free hCG Subunit Secretions in Ectopic Pregnancy". |
Am. J. Human Genetics, vol. 43, No. 3, Sep. 1988, Bharathur et al.: "Amniotic fluid beta hCG levels Associated with Down syndrome and Other Chromosome Abnormalities". |
Conference Poster, Society of Perinatal Obstetricians, Feb. 7-8, 1992, Rotmensch et al., "Peptide Heterogeneity of Human Chorionic Gonadotropin (hCG) and Its .beta.-Subunit in Down Syndrome Pregnancies". |
The Lancet, Oct. 8, 1988, p. 851, Cuckle eta l., "First-Trimester Biochemical Screening For Down Syndrome". |
Prenatal Diagnosis, vol. 10, 245-251 (1990), Brock et al., "First-Trimester Maternal Serum Biochemical Indicators in Down Syndrome". |
The Yale Journal of Biology and Medicine; 64 (1991), 627-637, Cole et al., "The Biological and Clinical Significance of Nicks in Human Chorionic Gonadotropin and Its Free .beta.-Subunit". |
Clin. Chem. 38/1, 26-33 (1992), Kardana et al., "Polypeptide Nicks Cause Erroneous Results in Assays of Human Chorionic Gonadotropin Free .beta.-Subunit". |
Clin. Chem. 37/6, 809-814 (1991), Spencer, K. "Evaluation of an Assay of the Free .beta.-Subunit of Choriogonadotropin and Its Potential Value in Screening for Down's Syndrome". |
J. Endocr. (1980), 84 295-310, Storring, P. et al. "International Reference Preparation of Human Chorionic Gonadotrophin For Immunoassay: Potency Estimates in Various Bioassay and Protein Binding Assay Systems; And International Reference Preparations of the Alpha and .beta. Subunits for Human Chorionic Gonadotrophin for Immunoassay". |
Am J Obstet Gynecol, vol. 155, No. 2, pp. 240-246, Aug. 1986, Macri, J. "Critical Issues in prenatal maternal serum Alpha-fetoprotein screening for genetic anomalies". |
Am J Obstet Gynecol. vol. 148, pp. 241-254, Feb. 1984, Adams et al., "Clinical interpretation of maternal serum alpha-fetoprotein concentrations". |
Clin. Chem. 36/4, 651-655 (1990), Thomas et al., Human Choriogonadotropin (hCG): Comparison between Determinations of Intact hCG, Free HCB .beta.-Subunit, "Total" hCG+.beta. in Serum during the First Half of High-Risk Pregnancy. |
American Journal of Medical Genetics, 36:480-483 (1990), Ozturk et al., "Abnormal Maternal Serum Levels of Human Chorionic Gonadotropin Free Subunits in Trisomy 18". |
American Journal of Obstetrics and Gynecology, vol. 163, No. 4, pp. 1248-1253, Oct. 1990, Macri et al., "Maternal Serum Down Syndrome Screening: Free .beta.-Protein is a More Effective Marker than Human Chorionic Gonadotropin". |
Endocrinology, vol. 126, No. 2, pp. 687-694 (1990), Puisieux et al., "Occurrence of Fragmentation of Free and Combined Forms of the .beta.-Subunit of Human Chorionic Gonadotropin". |