Downhole systems may be used to drill, service, or perform other operations on a wellbore in a surface location or a seabed for a variety of exploratory or extraction purposes. For example, a wellbore may be drilled to access valuable subterranean resources, such as liquid and gaseous hydrocarbons and solid minerals stored in subterranean formations, and to extract the resources from the formations.
Drilling systems are conventionally used to remove material from earth formations and other material, such as concrete, through primarily mechanical means. Drag bits, roller cone bits, reciprocating bits, and other mechanical bits fracture, pulverize, break, or otherwise remove material through the direct application of force. Different formations require different amounts of force to remove material. Increasing the amount of mechanical force applied to the formation includes increasing the torque and weight on bit on the drilling system, both of which introduce additional challenges to the drilling system.
Some mechanical bits include fluid conduits therethrough to direct drilling fluid to the cutting elements in order to flush cuttings and other debris from the cutting surfaces of the bit. Efficient removal of waste from the cutting area of the bit can reduce the torque and WOB used to remove material from the formation. Increasing the fluid pressure in a conventional bit erodes the bit and decreases the reliability and operational lifetime of the bit. A bit with one or more features that reduce the mechanical force to remove material from the formation without adversely affecting the reliability and lifetime of the bit is, therefore, desirable.
This summary is provided to introduce a selection of concepts that are further described below in the detailed description. This summary is not intended to identify key or essential features of the claimed subject matter, nor is it intended to be used as an aid in limiting the scope of the claimed subject matter.
In an embodiment, a device for removing material includes a bit body and a high-pressure (“HP”) body connected together. The high-pressure body has an HP fluid conduit that provides fluid communication through the HP body to at least one nozzle that is connected to the HP body. The HP fluid conduit is capable of withstanding fluid pressures greater than 40 kilopounds per square inch (kpsi) (276 megapascals (MPa)).
In another embodiment, a bit includes a bit body and an HP body connected together. The high-pressure body has an HP fluid conduit that provides fluid communication through the HP body to at least one nozzle that is connected to the HP body. The bit body has a center axis about which the bit can rotate. The bit body also has a low-pressure (“LP”) fluid conduit located in the body. The HP fluid conduit is capable of withstanding fluid pressures greater than 40 kpsi (276 MPa).
In yet another embodiment, a method of removing material from a formation includes flowing a fluid through an HP fluid conduit in a bit at a fluid pressure greater than 40 kpsi (276 MPa), directing the fluid at the formation in a fluid jet, weakening the formation with the fluid jet to create a weakened region of the formation, removing at least a portion of the weakened region as cuttings, and flushing the cuttings from the weakened region.
In a yet further embodiment, a method of manufacturing a bit is described. The method includes forming an HP body with an HP fluid conduit therein, forming a bit body, and joining the HP body and the bit body.
Additional features of embodiments of the disclosure will be set forth in the description which follows, and in part will be obvious from the description, or may be learned by the practice of such embodiments. The features of such embodiments may be realized and obtained by means of the instruments and combinations particularly pointed out in the appended claims. These and other features will become more fully apparent from the following description and appended claims, or may be learned by the practice of such embodiments as set forth hereinafter.
In order to describe the manner in which the above-recited and other features of the disclosure can be obtained, a more particular description will be rendered by reference to specific embodiments thereof which are illustrated in the appended drawings. For better understanding, the like elements have been designated by like reference numbers throughout the various accompanying figures. While some of the drawings may be schematic or exaggerated representations of concepts, at least some of the drawings may be drawn to scale. Understanding that the drawings depict some example embodiments, the embodiments will be described and explained with additional specificity and detail through the use of the accompanying drawings in which:
One or more specific embodiments of the present disclosure will be described below. These described embodiments are examples of the presently disclosed techniques. Additionally, in an effort to provide a concise description of these embodiments, not all features of an actual embodiment may be described in the specification. It should be appreciated that in the development of any such actual implementation, as in any engineering or design project, numerous embodiment-specific decisions will be made to achieve the developers' specific goals, such as compliance with system-related and business-related constraints, which may vary from one embodiment to another. Moreover, it should be appreciated that such a development effort might be complex and time consuming, but would nevertheless be a routine undertaking of design, fabrication, and manufacture for those of ordinary skill having the benefit of this disclosure.
This disclosure generally relates to devices, systems, and methods for directing a high-pressure fluid jet through a cutting bit. More particularly, the present disclosure relates to embodiments of cutting bits having a reinforced portion of the cutting bit to communicate a fluid therethrough at a pressure sufficient to remove material from an earth formation, thereby increasing a rate of penetration of the cutting bit, reducing the likelihood of a cutting element and/or a bit body failure, or combinations thereof. While a drill bit for cutting through an earth formation is described herein, it should be understood that the present disclosure may be applicable to other cutting bits such as milling bits, reamers, hole openers, and other cutting bits, and through other materials, such as cement, concrete, metal, or formations including such materials.
The drill string 105 may include several joints of drill pipe 108 a connected end-to-end through tool joints 109. The drill string 105 transmits drilling fluid through a central bore and transmits rotational power from the drill rig 103 to the BHA 106. In some embodiments, the drill string 105 may further include additional components such as subs, pup joints, etc. The drill pipe 108 provides a hydraulic passage through which drilling fluid is pumped from the surface. The drilling fluid discharges through selected-size nozzles, jets, or other orifices in the bit 110 for the purposes of cooling the bit 110 and cutting structures thereon, and for lifting cuttings out of the wellbore 102 as it is being drilled.
The BHA 106 may include the bit 110 or other components. An example BHA 106 may include additional or other components (e.g., coupled between to the drill string 105 and the bit 110). Examples of additional BHA components include drill collars, stabilizers, measurement-while-drilling (“MWD”) tools, logging-while-drilling (“LWD”) tools, downhole motors, underreamers, section mills, hydraulic disconnects, jars, vibration or dampening tools, other components, or combinations of the foregoing.
In general, the drilling system 100 may include other drilling components and accessories, such as special valves (e.g., kelly cocks, blowout preventers, and safety valves). Additional components included in the drilling system 100 may be considered a part of the drilling tool assembly 104, the drill string 105, or a part of the BHA 106 depending on their locations in the drilling system 100.
The bit 110 in the BHA 106 may be any type of bit suitable for degrading downhole materials. For instance, the bit 110 may be a drill bit suitable for drilling the earth formation 101. Example types of drill bits used for drilling earth formations are fixed-cutter or drag bits (see
The bit 210 includes an HP fluid conduit 217 and a LP fluid conduit 218. The HP fluid conduit 217 may flow fluid 219 to a nozzle 220. The nozzle 220 directs the fluid at a high-pressure toward a formation, casing, or other material to be cut and/or weakened by the fluid. The LP fluid conduit 218 may flow fluid through toward one or more openings in the bit body 211 to flush debris away from the body 211, arms 214, and roller cones 215.
The fluid 219 in the HP fluid conduit 217 and the LP fluid conduit 218 may be the same. In other embodiments, the fluid 219 in the HP fluid conduit 217 and the LP fluid conduit 218 may be different fluids. For example, the LP fluid conduit 218 may flow a drilling fluid (e.g., drilling mud) therethrough to flush debris from around the bit 210. The HP fluid conduit 217 may experience higher rates of wear and/or erosion due at least to the higher fluid pressures compared to the LP fluid conduit 218. The drilling fluid may contain particulates or contaminants in mixture and/or suspension that may damage the HP fluid conduit 217. The HP fluid conduit 217 may flow a fluid 219 that is free of particulates, such as clean water, clean oil, or other liquid free of particulates. In at least one embodiment, the HP fluid conduit 217 may be in fluid communication with an HP fluid pump (e.g., downhole pressure intensifier) located in the drill string (such as drill string 105 of
The HP fluid conduit 217 may contain the fluid 219 at a fluid pressure in a range having upper and lower values including any of 40 kilopounds per square inch (kpsi) (276 megapascals (MPa)), 45 kpsi (310 MPa), 50 kpsi (345 MPa), 55 kpsi (379 MPa), 60 kpsi (414 MPa), 65 kpsi (448 MPa), 70 kpsi (483 MPa), 75 kpsi (517 MPa), 80 kpsi (552 MPa), or any values therebetween. For example, the HP fluid conduit 217 may contain fluid 219 at a fluid pressure in a range of 40 kpsi (276 MPa) to 80 kpsi (552 MPa). In another example, the HP fluid conduit 217 may contain fluid 219 at a fluid pressure in a range of 50 kpsi (345 MPa) to 70 kpsi (483 MPa). In yet another example, the HP fluid conduit 217 may contain fluid 219 at a fluid pressure about 60 kpsi (414 MPa). In at least one embodiment, the fluid pressure of the HP fluid conduit 217 may be greater than 60 kpsi (414 MPa).
The HP fluid conduit 217 may be cast, machined, molded, or otherwise formed in an HP body 221. In some embodiments, the HP body 221 and the bit body 211 may be made of or include different materials. For example, the HP body 221 may be made of or include erosion resistant materials to withstand erosion by the movement of the fluid 219 in the HP fluid conduit 217. In another example, the HP body 221 may be made of or include high strength alloys or materials to limit or prevent cracking of the HP body when the fluid 219 is pressurized over 40 kpsi (276 MPa), over 50 kpsi (345 MPa), over 60 kpsi (414 MPa), etc.
In some embodiments, the HP body 221 may be made of or include high strength steel, low carbon steel, superalloys, Maraging (martensitic-aging) steel, tungsten carbide, PDC, or other erosion-resistant materials. The HP body 221 may be cast, machined, or built by additive manufacturing such that the HP fluid conduit 217 is integrally formed within the HP body 221. For example, the HP body 221 may be sand-cast with the HP fluid conduit 217 formed in the HP body 221. In another example, the HP fluid conduit 217 may be machined (i.e., bored) through a monolithic HP body 221 to produce the HP fluid conduit 217. In yet another example, additive manufacturing (such as selective laser melting (“SLM”) or selective laser sintering (“SLS”) may build up the HP body 221 one layer at a time while forming the HP fluid conduit 217 simultaneously.
The HP body 221 may be heat treated and/or tempered after the additive manufacturing. For example, the HP body 221 may be solubilized and/or normalized to homogenize the microstructure (e.g., inducing partial and/or complete recrystallization or grain growth) to alter the mechanical properties from the as-melted or as-sintered material.
The HP body 221 may be connected to the bit body 211 by a variety of connection methods or combinations thereof. In some embodiments, the HP body 221 may be bonded to the bit body 211, for example, by welding, brazing, or other bonding of the materials of the HP body 221 and the bit body 211. In other embodiments, the HP body 221 and the bit body 211 may be joined by one or more mechanically interlocking features, such as a tongue-and-groove connection, a dovetail connection, a friction fit, a pinned connection, or combinations thereof. For example, non-weldable materials, such as tungsten carbide may be joined by a sliding dovetail connection between the HP body 221 and the bit body 211, and the HP body 221 and bit body 211 may be fixed relative to one another by subsequent securing of the HP body 221 and the bit body 211 in the direction of the sliding dovetail (such as by welding a cap over the connection). In yet other embodiments, the HP body 221 and the bit body 211 may be joined with the use of one or more adhesives. In at least one embodiment, the HP body 221 and the bit body 211 may be joined by a combination of the foregoing, such as through welding of mechanically interlocking faces of the HP body 221 and the bit body 211.
The bit 310 may be rotatable, as described in relation to
In some embodiments, a nozzle 320 is integrally formed with the HP body 321. In other embodiments, the nozzle 320 be made of or include a different material from the HP body 321 and may be connected to the HP body 321 after manufacturing of the HP body 321. For example, the nozzle 320 may include or be made of an ultrahard material. As used herein, the term “ultrahard” is understood to refer to those materials known in the art to have a grain hardness of about 1,500 HV (Vickers hardness in kg/mm2) or greater. Such ultrahard materials can include but are not limited to diamond, sapphire, moissantite, polycrystalline diamond (PCD), leached metal catalyst PCD, non-metal catalyst PCD, hexagonal diamond (Lonsdaleite), cubic boron nitride (cBN), polycrystalline cBN (PcBN), binderless PCD or nanopolycrystalline diamond (NPD), Q-carbon, binderless PcBN, diamond-like carbon, boron suboxide, aluminum manganese boride, metal borides, boron carbon nitride, and other materials in the boron-nitrogen-carbon-oxygen system which have shown hardness values above 1,500 HV, as well as combinations of the above materials. In at least one embodiment, the nozzle 320 may be a monolithic PCD. For example, the nozzle 320 may consist of a PCD compact without an attached substrate. In another example, the nozzle 320 may have an ultrahard coating on an inner diameter of a substrate. In some embodiments, the ultrahard material may have a hardness values above 3,000 HV. In other embodiments, the ultrahard material may have a hardness value above 4,000 HV. In yet other embodiments, the ultrahard material may have a hardness value greater than 80 HRa (Rockwell hardness A).
As shown in
Referring now to
The nozzle 420 is located a radial position 428 from the center axis 416. In some embodiments, the radial position 428 of the nozzle 420 may be in a range having upper and lower values including any of 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 100%, or any values therebetween of the total radius of the bit 410 (i.e., the distance from the center axis 416 to a gage surface). For example, the nozzle 420 may have a radial position 428 that is in a range of 50% to 100% of the total radius of the bit 410. In another example, the nozzle 420 may have a radial position 428 that is in a range of 60% to 95% of the total radius of the bit 410. In yet another example, the nozzle 420 may have a radial position 428 that is in a range of 70% to 90% of the total radius of the bit 410.
As shown in the top view of the bit 510 in
The bit 510 is shown in
In some embodiments, the plurality of nozzles 520 may be fixed relative to the HP body 521. In other embodiments, the plurality of nozzles 520 may be movable relative to the HP body 521. For example, the plurality of nozzles 520 may be rotatable relative to the HP body 521. In other words, the four nozzles 520 at the end of the HP body 521 may rotate to distribute the HP fluid jet ejected from each nozzle over a larger area during use of the bit 510. The rotation of the nozzles 520, combined with the rotation of the bit 510 during use, may create a wave form, spiral function, or other repeating path pattern of the fluid jet.
While embodiments of roller cone bits have been described so far, an HP fluid conduit, according to the present disclosure, may be applicable in other applications, such as an embodiment of a PDC bit shown in
The PDC bit 610 may use one or more HP fluid conduits to deliver fluid to nozzles. In some embodiments, the PDC bit 610 has a first nozzle 620-1 on a primary blade and a second nozzle 620-2 on another primary blade 629. In other embodiments, a nozzle may be located on a secondary blade 630. In yet other embodiments, a nozzle may be located on the bit 610 between the primary blades 629 and secondary blades 630 in the body of the bit where the LP fluid conduits 618 are located.
The first nozzle 620-1 and second nozzle 620-2 may be located on different blades. In some embodiments, the first nozzle 620-1 and second nozzle 620-2 may be positioned on the bit 610 relative to the center axis 616 at an angular spacing 645 (similar to the angular spacing between roller cones in a roller cone bit embodiment). The angular spacing 645 may be in a range having upper and lower values including any of 0° (i.e., angularly aligned along a radial line from the center axis 616), 10°, 20°, 30°, 40°, 50°, 60°, 70°, 80°, 90°, 100°, 110°, 120°, 130°, 140°, 150°, 160°, 170°, 180° (i.e., opposing one another on opposite sides of the center axis 616), or any values therebetween. For example, the angular spacing 645 may be in a range of 0° to 180°. In another example, the angular spacing 645 may be in a range of 20° to 150°. In yet another example, the angular spacing 645 may be in a range of 40° to 120°.
The first nozzle 620-1 and second nozzle 620-2 may be located at the same radial distance or different radial distances. In some embodiments, the first nozzle 620-1 may be located at a first radial distance 628-1 and the second nozzle 620-2 may be located at a second radial distance 628-2 that is less than the first radial distance 628-1. In other embodiments, the first nozzle 620-1 may be located at a first radial distance 628-1 and the second nozzle 620-2 may be located at a second radial distance 628-2 that is greater than the first radial distance 628-1. In yet other embodiments, the first nozzle 620-1 may be located at a first radial distance 628-1 and the second nozzle 620-2 may be located at a second radial distance 628-2 that is the same as the first radial distance 628-1.
The second nozzle 620-2 is shown with a siderake angle 635 relative to the radial distance 628. The siderake angle 635 may be a positive siderake angle (away from the center axis 616), a negative siderake angle (toward the center axis 616), or a neutral siderake angle (parallel to the center axis 616). In some embodiments, the siderake angle 635 may be in a range having upper and lower values including any of −30°, −20°, −15°, −10°, −5°, 0°, 5°, 10°, 15°, 20°, 30°, or any values therebetween. For example, the siderake angle 635 may be in a range of −30° to 30°. In other examples, the siderake angle 635 may be in a range of −20° to 20°. In yet other examples, the siderake angle 635 may be in a range of −15° to 15°.
In some embodiments, a PDC bit may have integral HP fluid conduits that are cast into the bit body. In other embodiments such as the embodiment described in relation to
Some elements of a PDC bit and some elements of a roller cone bit may be combined in a hybrid bit, such as that shown in
The jet length 846 is a distance from the first nozzle 820-1 to the formation 801. In some embodiments, the jet length 846 may be in a range having upper and lower values including any of 0.05 in. (1.27 mm), 0.10 in. (2.54 mm), 0.15 in. (3.81 mm), 0.20 in. (5.08 mm), 0.25 in. (6.35 mm), 0.30 in. (7.62 mm), 0.35 in. (8.89 mm), 0.40 in. (10.2 mm), 0.45 in. (11.4 mm), 0.50 in. (12.7 mm), 0.55 in. (14.0 mm), 0.60 in. (15.2 mm), 0.65 in. (16.5 mm), 0.70 in. (17.8 mm), 0.75 in. (19.1 mm), 0.80 in. (20.3 mm), 0.85 in. (21.6 mm), 0.90 in. (22.9 mm), 0.95 in. (24.1 mm), 1.0 in. (25.4 mm), and any values therebetween. For example, a jet length 846 may be between 0.05 in. (1.27 mm) and 1.0 in. (25.4 mm). In other examples, a jet length 846 may be between 0.10 in. and 0.95 in. In yet other examples, a jet length 846 may be between 0.15 in. and 0.90 in.
The jet length 846, fluid pressure, rotational speed, downhole hydrostatic pressure, rock strength, rake angle (such as rake angle 634 described in relation to
A flowchart of an embodiment of a method 939 of using a bit according to the present disclosure is shown in
Additional aspects and features of the present disclosure are contemplated, and some such aspects and features will be appreciated in view of the included documents. For instance,
Fluid 921 in the HP pipe 924 may flow from a downhole pressure intensifier 928 (e.g., pump, motor) that takes fluid flow in the downhole BHA 906 and increases pressure. In some embodiments, the downhole pressure intensifier 928 (DPI) is coupled directly to the drill bit 910. The DPI 928 may be indirectly coupled to the drill bit 910 via intermediate components 918, such as components 918 of the BHA 906. In some embodiments, the DPI 928 is disposed on a surface, and the DPI 928 supplies the HP fluid 921 to the HP pipe 924, which directs the HP fluid 921 to the fluid conduit 917 of the drill bit 910.
The fluid 921 having the increased pressure from the DPI 928 will flow into the HP pipe 924. A second fluid (e.g., LP fluid 923) in the downhole system 908 may flow through the DPI 928 without pressure intensification or with reduced pressure intensification. In some embodiments, the LP fluid 923 may flow around the DPI 928. As a result, there may be both high pressure fluid 921 and low-pressure fluid 923 to the drill bit 910. The high-pressure fluid 921 may go through the drill bit fluid conduit 917 and into the HP nozzles 920, while the low-pressure fluid 923 may go through the drill bit 910 and into one or more lower pressure nozzles 922 via the passage 932. In some embodiments, the low pressure fluid 923 may be directed from the passage 932 to a plenum within the drill bit 910 for distribution to the one or more low pressure nozzles 922. In at least some embodiments, the high-pressure nozzles 920, high-pressure pipe 924, and fluid conduit 917 receive flow-pressure or flow rates consistent with the high-pressure flows discussed herein, while the bit plenum and low-pressure nozzles 922 receive fluid pressure generally consistent with a standard bit. For example, the HP fluid 921 may have a pressure greater than 14.5 ksi, 20 ksi, 25 ksi, 30 ksi, 40 ksi, 50 ksi, 60 ksi, or more. The LP fluid 923 may have a pressure less than the HP fluid 921 that is suitable for removing cuttings from the wellbore, such as less than 14.5 ksi, 10 ksi, 5 ksi, 1 ksi, or less. In some embodiments, the high-pressure and low-pressure nozzles may extend from the drill bit 910 at about a same axial position; however, in other embodiments, the high-pressure nozzles 920 may extend farther downhole than the low-pressure nozzles 922, or vice versa. According to at least some embodiments, the high-pressure nozzles 920 may provide flow 921 with reduced cuttings removable capabilities as compared to the low-pressure nozzles 922.
The system 908 of
The embodiment of
Embodiments of the present disclosure have shown preliminary results that are promising for the field. For instance, an example embodiment of a drill bit with one high-pressure nozzle was shown to have a 70% rate of penetration increase relative to a comparable standard roller cone bit when drilling in granite. An example embodiment with two high-pressure nozzles was shown to have a 42% rate of penetration increase over the baseline bit.
In operation, embodiments may include connecting an HP connector/pipe to a rigid bit connection and sliding a flexible connector through the box connection of the downhole pressure intensifier. The box connection may be coupled to the bit pin. Optionally, swivels, axial compensation, access windows, or other techniques may be used to facilitate high-pressure connections.
While embodiments of bits and fluid conduits have been primarily described with reference to wellbore drilling operations, the bits and fluid conduits described herein may be used in applications other than the drilling of a wellbore. In other embodiments, bits and fluid conduits according to the present disclosure may be used outside a wellbore or other downhole environment used for the exploration or production of natural resources. For instance, bits and fluid conduits of the present disclosure may be used in a borehole used for placement of utility lines. In other examples, bits and fluid conduits of the present disclosure may be used in wireline applications and/or maintenance applications. Accordingly, the terms “wellbore,” “borehole,” and the like should not be interpreted to limit tools, systems, assemblies, or methods of the present disclosure to any particular industry, field, or environment.
When introducing elements of various embodiments of the present disclosure, the articles “a,” “an,” and “the” are intended to mean that there are one or more of the elements. The terms “comprising,” “including,” and “having” are intended to be inclusive and mean that there may be additional elements other than the listed elements. Additionally, it should be understood that references to “one embodiment” or “an embodiment” of the present disclosure are not intended to be interpreted as excluding the existence of additional embodiments that also incorporate the recited features. It should be understood that any directions or reference frames in the preceding description are merely relative directions or movements. For example, any references to “up” and “down” or “above” and “below” are merely descriptive of the relative position or movement of the related elements. Any element described in relation to an embodiment or a figure herein may be combinable with any element of any other embodiment or figure described herein.
Any element described in relation to an embodiment or a figure herein may be combinable with any element of any other embodiment or figure described herein. Numbers, percentages, ratios, or other values stated herein are intended to include that value, and also other values that are “about” or “approximately” the stated value, as would be appreciated by one of ordinary skill in the art encompassed by embodiments of the present disclosure. A stated value should therefore be interpreted broadly enough to encompass values that are at least close enough to the stated value to perform a desired function or achieve a desired result. The stated values include at least the variation to be expected in a suitable manufacturing or production process, and may include values that are within 5%, within 1%, within 0.1%, or within 0.01% of a stated value.
A person having ordinary skill in the art should realize in view of the present disclosure that equivalent constructions do not depart from the spirit and scope of the present disclosure, and that various changes, substitutions, and alterations may be made to embodiments disclosed herein without departing from the spirit and scope of the present disclosure. Equivalent constructions, including functional “means-plus-function” clauses are intended to cover the structures described herein as performing the recited function, including both structural equivalents that operate in the same manner, and equivalent structures that provide the same function. It is the express intention of the applicant not to invoke means-plus-function or other functional claiming for any claim except for those in which the words ‘means for’ appear together with an associated function. Each addition, deletion, and modification to the embodiments that falls within the meaning and scope of the claims is to be embraced by the claims.
The terms “approximately,” “about,” and “substantially” as used herein represent an amount close to the stated amount that still performs a desired function or achieves a desired result. For example, the terms “approximately,” “about,” and “substantially” may refer to an amount that is within less than 5% of, within less than 1% of, within less than 0.1% of, and within less than 0.01% of a stated amount. Further, it should be understood that any directions or reference frames in the preceding description are merely relative directions or movements. For example, any references to “up” and “down” or “above” or “below” are merely descriptive of the relative position or movement of the related elements.
The present disclosure may be embodied in other specific forms without departing from its spirit or characteristics. The described embodiments are to be considered as illustrative and not restrictive. The scope of the disclosure is, therefore, indicated by the appended claims rather than by the foregoing description. Changes that come within the meaning and range of equivalency of the claims are to be embraced within their scope.
The project leading to this application has received funding from the European Union's Horizon 2020 research and innovation program under Grant Agreement No. 641202.
This application is a U.S. national stage entry of International Patent Application No. PCT/US2019/033035, filed May 20, 2019, which application claims priority from U.S. Provisional Application No. 62/674,512, filed May 21, 2018, herein incorporated by reference in its entirety.
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PCT/US2019/033035 | 5/20/2019 | WO |
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WO2019/226505 | 11/28/2019 | WO | A |
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