Embodiments generally relate to a shuttle pump. More particularly, embodiments relate to a multiple pulse shuttle pump and valve assembly.
Many drug delivery devices use conventional reciprocating pumping mechanisms to deliver fluid from a reservoir to a user. These conventional reciprocating pumping mechanisms are typically one-to-one (1:1) reciprocating pumping mechanisms that accommodate miniaturization, thereby enabling the overall drug delivery device to be smaller and more compact.
Furthermore, current pumping mechanisms include a valve switch to allow the user to fill the reservoir and to dispense a fluid (e.g., insulin). The valve must be shut while the user fills the reservoir, and open when the pump begins working. The valve must also differentiate between filling and dispensing of the pump. This entails three states for the valve, e.g., closed, open for filling, and open for dispensing. However, due to the small size of the dimensions of these conventional pumps, precision tolerances for these conventional pumps are very difficult to meet in view of dosage accuracy requirements.
Therefore, there is a need for an improved pumping mechanism to use with reservoirs that can be made small and compact while achieving a desired dosage accuracy.
In one approach of the disclosure, a shuttle pump system may include a pump chamber, a valve operable with the pump chamber, and a wire coupled to a valve shaft of the valve for controlling a position of the valve. The shuttle pump system may further include a pin disposed within an inset pathway of a cam, wherein the pin is moveable between multiple positions of the inset pathway in response to actuation of the valve shaft.
In another approach of the disclosure, a valve assembly may include a valve operable with a pump chamber, a wire coupled to a valve shaft of the valve for controlling a position of the valve, and a pin disposed within an inset pathway of a cam, wherein the pin is moveable between multiple positions of the inset pathway in response to actuation of the valve shaft.
In another approach of the disclosure, a wearable drug delivery system may include a pump chamber, a valve operable to control a fluid entering or exiting the pump chamber, and a wire coupled to a valve shaft of the valve for controlling a position of the valve, wherein the wire is a shape memory alloy (SMA) wire. The wearable drug delivery system may further include a pin disposed within an inset pathway of a cam, wherein the pin is moveable between multiple positions of the inset pathway in response to actuation of the valve shaft.
The accompanying drawings illustrate example approaches of the disclosure, including the practical application of the principles thereof, as follows:
The drawings are not necessarily to scale. The drawings are merely representations, not intended to portray specific parameters of the disclosure. The drawings are intended to depict example embodiments of the disclosure, and therefore are not be considered as limiting in scope. In the drawings, like numbering represents like elements.
Furthermore, certain elements in some of the figures may be omitted, or illustrated not-to-scale, for illustrative clarity. The cross-sectional views may be in the form of “slices”, or “near-sighted” cross-sectional views, omitting certain background lines otherwise visible in a “true” cross-sectional view, for illustrative clarity. Furthermore, some reference numbers may be omitted in certain drawings.
This disclosure presents various systems, components, and methods for creating a multiple pulse volume shuttle pump operated by a wire. Each of the systems, components, and methods disclosed herein provides one or more advantages over conventional systems, components, and methods. The approaches herein may be embodied in many different forms and are not to be construed as being limited to the embodiments set forth herein. Instead, these embodiments are provided so this disclosure will be thorough and complete, and will fully convey the scope of the approaches to those skilled in the art.
Various embodiments include a multiple pulse volume shuttle pump. The shuttle pump can be powered by an SMA wire. The SMA wire can be coupled to a pumping piston of the shuttle pump. A pin can be coupled to a piston grip that can be coupled to the SMA wire and the pumping piston. The pin can be disposed within a path of a movement guide. As the SMA wire is sequentially activated and deactivated to pulse the SMA wire, the movement guide and the pin can move in response to extend a stroke length of the shuttle pump, thereby increasing the accuracy of the shuttle pump.
Various embodiments provide an approximately 3:1 to 5:1 reciprocating pump while enabling the use of an SMA wire. The pump can fully reset after 3-5 pulses according to various designs. The total wire stroke can be increased, for example, by the number of pulses per full cycle of the pump. As a result, the overall size of certain components of the pump system can be made larger without substantially increasing the overall size of the drug delivery device in which it is used. Further, the larger stroke results in improved volume accuracy as precision tolerances are less difficult to meet.
Various embodiments use a “push-push” mechanism to actuate between multiple states. For example, with the SMA wire, a valve goes from closed, open to filling, and open to dispensing. The user may the reservoir once for the device, so the closed state of the valve may only be employed during manufacturing. After a first actuation of the SMA wire, the mechanism cycles through the two open states for filling and dispensing. The SMA wire may be pulled against the frictional forces of valve and valve shaft, as well as return springs that hold the valve in the correct state while the SMA wire is inactive. In one non-limiting implementation, a bracket, which moves along a face of the piston chamber, is coupled to the SMA wire and to the valve shaft for actuating the valve between multiple states. Extruding from a wall of the piston chamber may be a pin operable to traverse a track of the bracket. The track and pin can be switched from either the bracket or the piston chamber interchangeably.
In another non-limiting implementation, a chamber contains a track along an interior wall of a cylinder defining the chamber. A pin may extend into the chamber, moving along the track to actuate the valve between multiple states. The pin may be an angled or bent needle, which is attached to a bracket. The bracket may be further coupled to the valve shaft, and therefore stabilizes both the pin and the valve shaft as the valve shaft switches between the different valve states. The bent needle and the valve shaft may move together linearly, wherein the bent needle follows the defined track as the chamber rotates. In some embodiments, a return spring holds the valve shaft in the different hold states.
As shown in
For simplicity, only a portion of the shuttle pump 106 is shown with the portion shown in a simplified manner for clarity. In general, the shuttle pump 106 can be coupled to a reservoir or chamber storing a fluid and can also be coupled to an exit port that can accept expelled fluid from the shuttle pump 106.
During operation, the SMA wire 120 can be activated to pull on the piston pump 108. The SMA wire 120 can attempt to move the piston pump 108 in a first direction parallel to the y-axis 128 away from the first and second anchors 116 and 118. When the SMA wire 120 is not activated, the SMA wire 120 can relax and the first and second springs 112 and 114 can attempt to move the piston pump 108 in a second direction (e.g., opposite the first direction) parallel to the y-axis 128 toward the first and second anchors 116 and 118.
Activation and deactivation of the SMA wire 120 can cause the pin 122 to traverse the path 124. To accommodate movement of the pin 122 through the path 124, the cam block 104 can move within the slot 132. In various embodiments, the cam block 104 can move in directions parallel to the x-axis 126 as the SMA wire 120 is alternatively activated and relaxed, thereby allowing the pin 122 (and the pumping piston 108) to move in directions parallel to the y-axis 128 while traversing the path 124. In general, operation of the system 100 causes the pin 122 (and the pumping piston 108) to move (e.g., linearly) in directions parallel to the y-axis 128 while the cam block moves in directions parallel to the x-axis 126.
A full stroke of the system 100 can correspond to the pin 122 traversing the entire path 124. Activation of the SMA wire 120 can correspond to a pulse of the system 100. For each pulse, the pin 122 traverses a portion of the path 124. A portion of the full stroke of the system 100 can correspond to the pin traversing a portion of the path 124. The path 124, as described herein, can be shaped and/or can have features to provide designated positions or states of the pin 122 corresponding to each pulse. Sequential activation and deactivation of the SMA wire 120, as described herein, can extend or make longer the stroke of the piston pump 108.
Reference element 130 represents a point of view of the system 100 shown in
As further shown in
As further shown in
The interface between sequential or adjacent sections can include drop offs to guide movement of the pin 122 as it traverses the path 124. Along with the first drop off 308, a second drop off 310 can be positioned between the sections 304-1 and 306-1, a third drop off 312 can be positioned between sections 306-1 and 304-2, a fourth drop off 314 can be positioned between sections 304-2 and 306-2, a fifth drop off 316 can be positioned between sections 306-2 and 304-3, and a sixth drop off 318 can be positioned between the sections 304-3 and 302.
The sloping of the different sections of the path 124 and the drop offs positioned between the different sections of the path 124 can ensure the pin 122 traverses a desired route along the path based on the sequential activation/deactivation of the SMA wire 120. For example, after traversing the section 304-1, the pin 122 can fall down from the elevated portion of the section 304-1 into the lowered portion of the section 306-1—with the interface between the elevated portion of the section 304-1 and the lowered portion of the section 306-1 forming the drop off 310. The drop 310 can prevent the pin 122 from traveling from the section 306-1 back into the section 304-1.
The route 402 traversed by the pin 122 can be broken into multiple pulses. Based on control of the SMA wire 120 in relation to the features provided by the path 124, the route 402 traversed by the pin 122 can be broken into two or more pulses. In an embodiment, the route 402 traversed by the pin 122 can be broken into three or more pulses. Each pulse can correspond to the SMA wire 120 being activated (e.g., after being relaxed). Additional positions or states of the pin 122 are further indicated by the subsequent positions, labeled “2” and “3” in
The first gate 1106 is shown in an open position, allowing movement of the ball bearing 1102 beyond the first gate 1106. The gate backstop 1108 can block the first gate 1106 from swinging too far when in a closed position. The second gate 1110 is shown in a closed position and so can restrict further movement of the ball bearing 1102 in a direction past the second gate 1110. By restricting movement of the ball bearing 1102, the second gate 1110 (or any closed gate) can interrupt operation of the pumping piston 108, for example, by interrupting a filling process of the pumping piston 108 at predetermined volume intervals. A gate actuator 1112 can control motion of the second gate 1110. Each gate can be controlled by a corresponding gate actuator to be in an open or a closed position.
The system 1100 is not limited to the number of gates shown as any number of gates can be used with the system 1100. Further, each gate can be accompanied by a gate backstop to set a closed position for a corresponding gate. The SMA wire 120, when activated, can pull on the ball bearing 1102 in a direction from the open gate 1106 to the closed gate 1110 (e.g., towards the closed end of the housing 1114). When deactivated, the ball bearing 1102 can be pulled in the opposite direction. For each direction, movement of the ball bearing 1102 can be regulated by the gates 1106 and 1110, to control filling of the pumping piston 108 with a fluid and to control expelling the fluid from the pumping piston 108. In particular, the gates 1106 and 1110 can control the movement of the ball bearing 1102 and corresponding linear motion of the pumping piston 108 at fixed predetermined intervals or positions based on pulses of the SMA wire 120.
The system 100 may further include a cam bracket 1450 of the system 1400. As shown, the cam bracket 1450 may couple together the wire 1420 and the valve shaft 1408. In some embodiments, the cam bracket 1450 includes a pair of curled ends 1451, 1452 engaged with the valve shaft 1408. As shown, the valve shaft 1408 may include a first section 1408-1 extending perpendicular to a second section 1408-2. For example, the first section 1408-1 may generally extend parallel to the x-direction, and the second section 1408-2 may generally extend parallel to the y-direction. In some embodiments, curled end 1451 may be directly coupled to the wire 1420, and curled end 1452 may be coupled to one or more springs 1454. During operation, the spring 1454 may bias the cam bracket 1450 along the positive x-direction, while the wire 1420 may bias the cam bracket 1450 along the negative x-direction when pulled. To maintain alignment thereof, the cam bracket 1450 may be disposed between an exterior surface 1458 of the pump chamber 1440 and a bracket wall 1460. In some embodiments, the bracket wall 1460 is coupled to both the valve 1447 and the pump chamber 1440.
As shown in
Turning now to
As demonstrated in
As demonstrated in
As demonstrated in
As demonstrated in
Turning now to
As further shown, the valve assembly 1745 may include a chamber 1748 adjacent the valve 1747, the chamber 1748 including an asymmetrical inset pathway 1704 along an interior surface thereof. The valve assembly 1745 may further include a second shaft 1750 extending within the chamber 1745, wherein a pin 1775 extends from an end of the second shaft 1750, and wherein movement of the pin 1775 within the inset pathway 1704 causes the chamber 1748 to rotate about the second shaft 1750. As shown, the second shaft 1750 may be configured as a bent needle, wherein the pin 1775 generally extends perpendicular to the remainder of the second shaft 1750. The inset pathway 1704 wraps around an interior of the chamber 1748, restricting the pin 1775 to follow a desired path. Numbers (1), (2), and (3) along the inset pathway 1704 in
The valve assembly 1745 may include a bracket 1751 coupling together the valve shaft 1708 and the second shaft 1750. Although non-limiting, the bracket 1751 may be configured as plate including a cylindrical receptacle 1753 receiving the second shaft 1750 and a curled arm 1754 receiving the valve shaft 1708. As shown, the wire 1720 may be directly coupled to the bracket 1751.
As best shown in
In the initial state shown in
Next, as demonstrated in
Next, as demonstrated in
The foregoing discussion has been presented for purposes of illustration and description and is not intended to limit the disclosure to the form or forms disclosed herein. For example, various features of the disclosure may be grouped together in one or more aspects, embodiments, or configurations for the purpose of streamlining the disclosure. However, it should be understood that various features of the certain aspects, embodiments, or configurations of the disclosure may be combined in alternate aspects, embodiments, or configurations.
As used herein, an element or step recited in the singular and proceeded with the word “a” or “an” should be understood as not excluding plural elements or steps, unless such exclusion is explicitly recited. Furthermore, references to “one embodiment” of the present disclosure are not intended to be interpreted as excluding the existence of additional embodiments that also incorporate the recited features.
The use of “including,” “comprising,” or “having” and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items. Accordingly, the terms “including,” “comprising,” or “having” and variations thereof are open-ended expressions and can be used interchangeably herein.
The phrases “at least one”, “one or more”, and “and/or”, as used herein, are open-ended expressions that are both conjunctive and disjunctive in operation. For example, each of the expressions “at least one of A, B and C”, “at least one of A, B, or C”, “one or more of A, B, and C”, “one or more of A, B, or C” and “A, B, and/or C” means A alone, B alone, C alone, A and B together, A and C together, B and C together, or A, B and C together.
All directional references (e.g., proximal, distal, upper, lower, upward, downward, left, right, lateral, longitudinal, front, back, top, bottom, above, below, vertical, horizontal, radial, axial, clockwise, and counterclockwise) are only used for identification purposes to aid the reader's understanding of the present disclosure, and do not create limitations, particularly as to the position, orientation, or use of this disclosure. Connection references (e.g., attached, coupled, connected, and joined) are to be construed broadly and may include intermediate members between a collection of elements and relative movement between elements unless otherwise indicated. As such, connection references do not necessarily infer that two elements are directly connected and in fixed relation to each other.
Furthermore, identification references (e.g., primary, secondary, first, second, third, fourth, etc.) are not intended to connote importance or priority but are used to distinguish one feature from another. The drawings are for purposes of illustration only and the dimensions, positions, order and relative sizes reflected in the drawings attached hereto may vary.
Furthermore, the terms “substantial” or “substantially,” as well as the terms “approximate” or “approximately,” can be used interchangeably in some embodiments, and can be described using any relative measures acceptable by one of ordinary skill in the art. For example, these terms can serve as a comparison to a reference parameter, to indicate a deviation capable of providing the intended function. Although non-limiting, the deviation from the reference parameter can be, for example, in an amount of less than 1%, less than 3%, less than 5%, less than 10%, less than 15%, less than 20%, and so on.
Still furthermore, although the various methods disclosed herein are described as a series of acts or events, the present disclosure is not limited by the illustrated ordering of such acts or events unless specifically stated. For example, some acts may occur in different orders and/or concurrently with other acts or events apart from those illustrated and/or described herein, in accordance with the disclosure. In addition, not all illustrated acts or events may be required to implement a methodology in accordance with the present disclosure. Furthermore, the methods may be implemented in association with the formation and/or processing of structures illustrated and described herein as well as in association with other structures not illustrated.
The present disclosure is not to be limited in scope by the specific embodiments described herein. Indeed, other various embodiments of and modifications to the present disclosure, in addition to those described herein, will be apparent to those of ordinary skill in the art from the foregoing description and accompanying drawings. Thus, such other embodiments and modifications are intended to fall within the scope of the present disclosure. Furthermore, the present disclosure has been described herein in the context of a particular implementation in a particular environment for a particular purpose. Those of ordinary skill in the art will recognize the usefulness is not limited thereto and the present disclosure may be beneficially implemented in any number of environments for any number of purposes. Thus, the claims set forth below are to be construed in view of the full breadth and spirit of the present disclosure as described herein.
This application claims priority to U.S. Provisional Patent Application No. 62/772,547 filed Nov. 28, 2018, the entire contents of the application incorporated by reference herein.
Number | Name | Date | Kind |
---|---|---|---|
1441508 | Jensen | Jan 1923 | A |
2198666 | Gruskin | Apr 1940 | A |
2752918 | Uytenbogaart et al. | Jul 1956 | A |
3176712 | Ramsden | Apr 1965 | A |
3297260 | Barlow | Jan 1967 | A |
3464359 | King | Sep 1969 | A |
3885662 | Schaefer | May 1975 | A |
3946732 | Hurscham | Mar 1976 | A |
3947692 | Payne | Mar 1976 | A |
3993061 | OLeary | Nov 1976 | A |
4108177 | Pistor | Aug 1978 | A |
4152098 | Moody et al. | May 1979 | A |
4210173 | Choksi et al. | Jul 1980 | A |
4221219 | Tucker | Sep 1980 | A |
4257324 | Stefansson et al. | Mar 1981 | A |
4268150 | Chen | May 1981 | A |
4313439 | Babb | Feb 1982 | A |
4371790 | Manning et al. | Feb 1983 | A |
4417889 | Choi | Nov 1983 | A |
4424720 | Bucchianeri | Jan 1984 | A |
4435173 | Siposs et al. | Mar 1984 | A |
4475905 | Himmelstrup | Oct 1984 | A |
4498843 | Schneider et al. | Feb 1985 | A |
4507115 | Kambara et al. | Mar 1985 | A |
4551134 | Slavik et al. | Nov 1985 | A |
4562751 | Nason et al. | Jan 1986 | A |
4567549 | Lemme | Jan 1986 | A |
4585439 | Michel | Apr 1986 | A |
4601707 | Albisser et al. | Jul 1986 | A |
4634427 | Hannula et al. | Jan 1987 | A |
4671429 | Spaanderman et al. | Jun 1987 | A |
4678408 | Nason et al. | Jul 1987 | A |
4684368 | Kenyon | Aug 1987 | A |
4685903 | Cable et al. | Aug 1987 | A |
4755169 | Sarnoff et al. | Jul 1988 | A |
4766889 | Trick et al. | Aug 1988 | A |
4808161 | Kamen | Feb 1989 | A |
4846797 | Howson et al. | Jul 1989 | A |
4858619 | Toth | Aug 1989 | A |
4898579 | Groshong et al. | Feb 1990 | A |
4908017 | Howson et al. | Mar 1990 | A |
4944659 | Labbe et al. | Jul 1990 | A |
4969874 | Michel et al. | Nov 1990 | A |
4991743 | Walker | Feb 1991 | A |
5007458 | Marcus et al. | Apr 1991 | A |
5020325 | Henault | Jun 1991 | A |
5062841 | Siegel | Nov 1991 | A |
5147311 | Pickhard | Sep 1992 | A |
5178609 | Ishikawa | Jan 1993 | A |
5205819 | Ross et al. | Apr 1993 | A |
5213483 | Flaherty et al. | May 1993 | A |
5222362 | Maus et al. | Jun 1993 | A |
5236416 | McDaniel et al. | Aug 1993 | A |
5261882 | Sealfon | Nov 1993 | A |
5261884 | Stern et al. | Nov 1993 | A |
5277338 | Divall et al. | Jan 1994 | A |
5281202 | Weber et al. | Jan 1994 | A |
5346476 | Elson | Sep 1994 | A |
5364342 | Beuchat et al. | Nov 1994 | A |
5388615 | Edlund et al. | Feb 1995 | A |
5433710 | VanAntwerp et al. | Jul 1995 | A |
5503628 | Fetters et al. | Apr 1996 | A |
5520661 | Lal et al. | May 1996 | A |
5533389 | Kamen et al. | Jul 1996 | A |
5582593 | Hultman | Dec 1996 | A |
5618269 | Jacobsen | Apr 1997 | A |
5628309 | Brown | May 1997 | A |
5637095 | Nason et al. | Jun 1997 | A |
5665070 | McPhee | Sep 1997 | A |
5713875 | Tanner, II | Feb 1998 | A |
5747350 | Sattler | May 1998 | A |
5748827 | Holl et al. | May 1998 | A |
5776103 | Kriesel et al. | Jul 1998 | A |
5779676 | Kriesel et al. | Jul 1998 | A |
5785688 | Joshi et al. | Jul 1998 | A |
5797881 | Gadot | Aug 1998 | A |
5800397 | Wilson et al. | Sep 1998 | A |
5807075 | Jacobsen et al. | Sep 1998 | A |
5839467 | Saaski et al. | Nov 1998 | A |
5891097 | Saito et al. | Apr 1999 | A |
5897530 | Jackson | Apr 1999 | A |
5906597 | McPhee | May 1999 | A |
5911716 | Rake et al. | Jun 1999 | A |
5919167 | Mulhauser et al. | Jul 1999 | A |
5957890 | Mann et al. | Sep 1999 | A |
5961492 | Kriesel et al. | Oct 1999 | A |
5971963 | Choi | Oct 1999 | A |
6019747 | McPhee | Feb 2000 | A |
6050457 | Arnold et al. | Apr 2000 | A |
6068615 | Brown et al. | May 2000 | A |
6086615 | Wood et al. | Jul 2000 | A |
6159188 | Laibovitz et al. | Dec 2000 | A |
6174300 | Kriesel et al. | Jan 2001 | B1 |
6190359 | Heruth | Feb 2001 | B1 |
6200293 | Kriesel et al. | Mar 2001 | B1 |
6352522 | Kim et al. | Mar 2002 | B1 |
6363609 | Pickren | Apr 2002 | B1 |
6375638 | Nason et al. | Apr 2002 | B2 |
6474219 | Klitmose et al. | Nov 2002 | B2 |
6485461 | Mason et al. | Nov 2002 | B1 |
6485462 | Kriesel | Nov 2002 | B1 |
6488652 | Weijand et al. | Dec 2002 | B1 |
6520936 | Mann | Feb 2003 | B1 |
6527744 | Kriesel et al. | Mar 2003 | B1 |
6537249 | Kriesell et al. | Mar 2003 | B2 |
6539286 | Jiang | Mar 2003 | B1 |
6569115 | Barker et al. | May 2003 | B1 |
6595956 | Gross et al. | Jul 2003 | B1 |
6656158 | Mahoney et al. | Dec 2003 | B2 |
6699218 | Flaherty et al. | Mar 2004 | B2 |
6723072 | Flaherty et al. | Apr 2004 | B2 |
6749407 | Xie et al. | Jun 2004 | B2 |
6851260 | Mernoe | Feb 2005 | B2 |
6883778 | Newton et al. | Apr 2005 | B1 |
7018360 | Flaherty et al. | Mar 2006 | B2 |
7104275 | Dille | Sep 2006 | B2 |
7128727 | Flaherty et al. | Oct 2006 | B2 |
7144384 | Gorman et al. | Dec 2006 | B2 |
7160272 | Eyal et al. | Jan 2007 | B1 |
7771392 | De Polo et al. | Aug 2010 | B2 |
7914499 | Gonnelli et al. | Mar 2011 | B2 |
7951114 | Rush | May 2011 | B2 |
8267921 | Yodfat et al. | Sep 2012 | B2 |
8382703 | Abdelaal | Feb 2013 | B1 |
8499913 | Gunter | Aug 2013 | B2 |
8905995 | Mernoe | Dec 2014 | B2 |
8920376 | Caffey et al. | Dec 2014 | B2 |
8939935 | OConnor et al. | Jan 2015 | B2 |
9180244 | Anderson et al. | Nov 2015 | B2 |
9192716 | Jugl et al. | Nov 2015 | B2 |
9402950 | Dilanni et al. | Aug 2016 | B2 |
9539596 | Ikushima | Jan 2017 | B2 |
10441723 | Nazzaro | Oct 2019 | B2 |
10695485 | Nazzaro | Jun 2020 | B2 |
20010016710 | Nason et al. | Aug 2001 | A1 |
20010056258 | Evans | Dec 2001 | A1 |
20020029018 | Jeffrey | Mar 2002 | A1 |
20020032374 | Holker et al. | Mar 2002 | A1 |
20020037221 | Mastrangelo et al. | Mar 2002 | A1 |
20020173769 | Gray et al. | Nov 2002 | A1 |
20020173830 | Starkweather et al. | Nov 2002 | A1 |
20030040715 | DAntonio et al. | Feb 2003 | A1 |
20030055380 | Flaherty | Mar 2003 | A1 |
20030097092 | Flaherty | May 2003 | A1 |
20030109827 | Lavi et al. | Jun 2003 | A1 |
20030163097 | Fleury et al. | Aug 2003 | A1 |
20030198558 | Nason | Oct 2003 | A1 |
20030199825 | Flaherty | Oct 2003 | A1 |
20040010207 | Flaherty et al. | Jan 2004 | A1 |
20040064088 | Gorman et al. | Apr 2004 | A1 |
20040068224 | Couvillon, Jr. et al. | Apr 2004 | A1 |
20040069044 | Lavi et al. | Apr 2004 | A1 |
20040092865 | Flaherty et al. | May 2004 | A1 |
20040094733 | Hower et al. | May 2004 | A1 |
20040153032 | Garribotto et al. | Aug 2004 | A1 |
20050020980 | Inoue et al. | Jan 2005 | A1 |
20050165363 | Judson et al. | Jul 2005 | A1 |
20050203461 | Flaherty et al. | Sep 2005 | A1 |
20050238507 | Dilanni et al. | Oct 2005 | A1 |
20050273059 | Mernoe | Dec 2005 | A1 |
20050277882 | Kriesel | Dec 2005 | A1 |
20060041229 | Garibotto et al. | Feb 2006 | A1 |
20060079765 | Neer et al. | Apr 2006 | A1 |
20060155210 | Beckman et al. | Jul 2006 | A1 |
20060173439 | Thorne et al. | Aug 2006 | A1 |
20060178633 | Garibotto et al. | Aug 2006 | A1 |
20060253085 | Geismar et al. | Nov 2006 | A1 |
20060282290 | Flaherty et al. | Dec 2006 | A1 |
20070005018 | Tekbuchava | Jan 2007 | A1 |
20070073236 | Mernoe et al. | Mar 2007 | A1 |
20070088271 | Richards | Apr 2007 | A1 |
20070118405 | Campbell et al. | May 2007 | A1 |
20070282269 | Carter et al. | Dec 2007 | A1 |
20080004515 | Jennewine | Jan 2008 | A1 |
20080051738 | Griffin | Feb 2008 | A1 |
20080114304 | Nalesso et al. | May 2008 | A1 |
20080172028 | Blomquist | Jul 2008 | A1 |
20080243211 | Cartwright et al. | Oct 2008 | A1 |
20080294040 | Mohiuddin et al. | Nov 2008 | A1 |
20090024083 | Kriesel et al. | Jan 2009 | A1 |
20090062767 | Van Antwerp et al. | Mar 2009 | A1 |
20090198215 | Chong et al. | Aug 2009 | A1 |
20090278875 | Holm et al. | Nov 2009 | A1 |
20090326472 | Carter et al. | Dec 2009 | A1 |
20100036326 | Matusch | Feb 2010 | A1 |
20100152658 | Hanson et al. | Jun 2010 | A1 |
20100241066 | Hansen et al. | Sep 2010 | A1 |
20110054399 | Chong et al. | Mar 2011 | A1 |
20110073620 | Verrilli | Mar 2011 | A1 |
20110144586 | Michaud et al. | Jun 2011 | A1 |
20110180480 | Kloeffel et al. | Jul 2011 | A1 |
20110230833 | Landman et al. | Sep 2011 | A1 |
20120078161 | Masterson et al. | Mar 2012 | A1 |
20120172817 | Bruggemann et al. | Jul 2012 | A1 |
20120209207 | Gray et al. | Aug 2012 | A1 |
20130006213 | Arnitz et al. | Jan 2013 | A1 |
20130017099 | Genoud | Jan 2013 | A1 |
20130064701 | Konishi | Mar 2013 | A1 |
20130177455 | Kamen et al. | Jul 2013 | A1 |
20130178803 | Raab | Jul 2013 | A1 |
20130245545 | Arnold et al. | Sep 2013 | A1 |
20130267932 | Franke et al. | Oct 2013 | A1 |
20130296792 | Cabiri | Nov 2013 | A1 |
20140018730 | Muller-Pathle | Jan 2014 | A1 |
20140127048 | Dilanni et al. | May 2014 | A1 |
20140128839 | Dilanni et al. | May 2014 | A1 |
20140142508 | Dilanni et al. | May 2014 | A1 |
20140148784 | Anderson et al. | May 2014 | A1 |
20140171901 | Langsdorf et al. | Jun 2014 | A1 |
20150041498 | Kakiuchi et al. | Feb 2015 | A1 |
20150051487 | Uber et al. | Feb 2015 | A1 |
20150057613 | Clemente et al. | Feb 2015 | A1 |
20150064036 | Eberhard | Mar 2015 | A1 |
20150137017 | Ambrosina et al. | May 2015 | A1 |
20150202386 | Brady et al. | Jul 2015 | A1 |
20150290389 | Nessel | Oct 2015 | A1 |
20150297825 | Focht et al. | Oct 2015 | A1 |
20160008549 | Plumptre et al. | Jan 2016 | A1 |
20160025544 | Kamen | Jan 2016 | A1 |
20160055842 | DeFranks et al. | Feb 2016 | A1 |
20160082242 | Burton et al. | Mar 2016 | A1 |
20160129190 | Haitsuka | May 2016 | A1 |
20160193423 | Bilton | Jul 2016 | A1 |
20160213851 | Weibel et al. | Jul 2016 | A1 |
20170021096 | Cole et al. | Jan 2017 | A1 |
20170021137 | Cole | Jan 2017 | A1 |
20170100541 | Constantineau et al. | Apr 2017 | A1 |
20170216516 | Dale | Aug 2017 | A1 |
20170239415 | Hwang et al. | Aug 2017 | A1 |
20170290975 | Barmaimon et al. | Oct 2017 | A1 |
20180021521 | Sanchez | Jan 2018 | A1 |
20180185579 | Joseph et al. | Jul 2018 | A1 |
20180313346 | Oakes | Nov 2018 | A1 |
20190192782 | Pedersen et al. | Jun 2019 | A1 |
20190365993 | Staub et al. | Dec 2019 | A1 |
20200009315 | Brouet et al. | Jan 2020 | A1 |
20200345931 | Gray et al. | Nov 2020 | A1 |
Number | Date | Country |
---|---|---|
606281 | Oct 1960 | CA |
1375338 | Oct 2002 | CN |
102498292 | Jul 2015 | CN |
204972511 | Jan 2016 | CN |
105764543 | Jul 2016 | CN |
206175149 | May 2017 | CN |
107096091 | Aug 2017 | CN |
108472441 | Aug 2018 | CN |
4200595 | Jul 1993 | DE |
19723648 | Aug 1998 | DE |
102005040344 | Mar 2007 | DE |
0454331 | Oct 1991 | EP |
0789146 | Aug 1997 | EP |
867196 | Sep 1998 | EP |
1065378 | Jan 2001 | EP |
1177802 | Feb 2002 | EP |
1403519 | Mar 2004 | EP |
2397181 | Dec 2011 | EP |
2468338 | Jun 2012 | EP |
2703024 | Mar 2014 | EP |
2830499 | Feb 2015 | EP |
2096275 | Feb 1972 | FR |
2455269 | Nov 1980 | FR |
2507637 | Dec 1982 | FR |
2731475 | Sep 1996 | FR |
357139 | Sep 1931 | GB |
810488 | Mar 1959 | GB |
875034 | Aug 1961 | GB |
1204836 | Sep 1970 | GB |
2008806 | Jun 1979 | GB |
2077367 | Dec 1981 | GB |
2456681 | Jul 2009 | GB |
2549750 | Nov 2017 | GB |
46017 | Nov 1977 | IL |
06063133 | Mar 1994 | JP |
H06296690 | Oct 1994 | JP |
H08238324 | Sep 1996 | JP |
2004247271 | Sep 2004 | JP |
2004274719 | Sep 2004 | JP |
2005188355 | Jul 2005 | JP |
2006159228 | Jun 2006 | JP |
6098988 | Sep 2006 | JP |
2006249130 | Sep 2006 | JP |
2009514580 | Apr 2009 | JP |
2017513577 | Jun 2017 | JP |
1019126 | Apr 2003 | NL |
8101658 | Jun 1981 | WO |
8606796 | Nov 1986 | WO |
WO-9320864 | Oct 1993 | WO |
9415660 | Jul 1994 | WO |
9855073 | Dec 1998 | WO |
9856293 | Dec 1998 | WO |
9910040 | Mar 1999 | WO |
9910049 | Mar 1999 | WO |
9962576 | Dec 1999 | WO |
0029047 | May 2000 | WO |
0178812 | Oct 2001 | WO |
0220073 | Mar 2002 | WO |
0226282 | Apr 2002 | WO |
2002076535 | Apr 2002 | WO |
2003097133 | Apr 2002 | WO |
02068823 | Sep 2002 | WO |
WO-2004032994 | Apr 2004 | WO |
2004056412 | Jul 2004 | WO |
2004110526 | Dec 2004 | WO |
2007066152 | Jun 2007 | WO |
2008133702 | Nov 2008 | WO |
2009039203 | Mar 2009 | WO |
2009141005 | Nov 2009 | WO |
2010022069 | Feb 2010 | WO |
2010077279 | Jul 2010 | WO |
2010139793 | Dec 2010 | WO |
2011010198 | Jan 2011 | WO |
2011031458 | Mar 2011 | WO |
2011075042 | Jun 2011 | WO |
WO-2011069935 | Jun 2011 | WO |
2011133823 | Oct 2011 | WO |
2012073032 | Jun 2012 | WO |
2013050535 | Apr 2013 | WO |
2013137893 | Sep 2013 | WO |
2013149186 | Oct 2013 | WO |
2014029416 | Feb 2014 | WO |
2014149357 | Sep 2014 | WO |
2014179774 | Nov 2014 | WO |
2015032772 | Mar 2015 | WO |
2015048791 | Apr 2015 | WO |
2015081337 | Jun 2015 | WO |
2015081337 | Jun 2015 | WO |
2015117854 | Aug 2015 | WO |
2015167201 | Nov 2015 | WO |
2015177082 | Nov 2015 | WO |
2017148855 | Sep 2017 | WO |
2017187177 | Nov 2017 | WO |
2021016452 | Jan 2021 | WO |
Entry |
---|
Schott web-page image from Jul. 9, 2016, https://www.us.schott.com/pharmaceutical_packaging/english/products/cartridges.html. |
International Search Report and Written Opinion for Application No. PCT/US2019/059854, dated Aug. 26, 2020, 15 pages. |
European Search Report and Written Opinion for the European Patent Application No. EP20174878, dated Sep. 29, 2020, 8 pages. |
International Search Report and Written Opinion for PCT/US2018/014351, dated Jun. 4, 2018, 9 pages. |
“Lind, et al. “Linear Motion Miniature Actuators.”” Paper presented at the 2nd Tampere International Conference onMachine Automation, Tampere, Finland (Sep. 1998). |
Author unknown, ““The Animas R-1000 Insulin Pump—Animas Corporation intends to exit the insulin pump businessand discontinue the manufacturing and sale of Animas® Vibe® and One Touch Ping® insulin pumps.”” [online],Dec. 1999 [retrieved on Jan. 8, 2019]. Retrieved from the Internet URL: http://www. animaspatientsupport.com/. |
Author unknown, CeramTec ““Discover the Electro Ceramic Products CeramTec acquired from Morgan AdvancedMaterials”” [online], Mar. 1, 2001 [retrieved on Jan. 8, 2019. Retrieved from the Internet URL: http://www.morgantechnicalceramics.com/. |
Vaughan, M.E., ““The Design, Fabrication, and Modeling of a Piezoelectric Linear Motor.”” Master's thesis,Virginia Polytechnic Institute and State University, VA. (2001). |
Galante, et al., “Design, Modeling, and Performance of a High Force Piezoelectric Inchworm Motor,” Journal of Intelligent Material Systems and Structures, vol. 10, 962-972 (1999). |
International Search Report and Written Opinion for Interantional application No. PCT/US2017/055054, dated Jan. 25, 2018, 14 pages. |
International Search Report and Written Opinion for International application No. PCT/US2018/045155, dated Oct. 15, 2018, 12 pages. |
ISR/WO International Preliminary Report on Patentability for International application No. PCT/US2017/034811 dated Nov. 27, 2018 10 pages. |
International Preliminary Report on Patentability for the International Patent Application No. PCT/US2017/046508 dated Feb. 12, 2019 10 pp. |
International Search Report and Written Opinion for International application No. PCT/US2017/046508, dated Jan. 17, 2018, 14 pages. |
International Search Report and Written Opinion for International application No. PCT/US2017/046777, dated Dec. 13, 2017, 14 pages. |
International Search Report and Written Opinion for International application No. PCT/US2017/046737, dated Dec. 14, 2017, 11 pages. |
International Search Report and Written Opinion for International application No. PCT/US2017/034814, dated Oct. 11, 2017, 16 pages. |
European Search Report and Written Opinion for the European Patent Application No. EP19177571, dated Oct. 30, 2019, 8 pages. |
ISR/WO International Preliminary Report on Patentability for the International Patent Application No. PCT/US 1814351, dated Aug. 1, 2019, 6 pages. |
International Preliminary Report on Patentability for the International Patent Application No. PCT/US2017/046777, dated Feb. 19, 2019, 8 pages. |
ISR/WO International Preliminary Report on Patentability for the International Patent Application No. PCT/US2017/046737, dated Feb. 19, 2019, 8 pages. |
ISR/WO International Preliminary Report on Patentability for the International Patent Application No. PCT/US2017/055054,dated Apr. 9, 2019, 8 pages. |
International Search Report and Written Opinion for application No. PCT/US2017/034811, dated Oct. 18, 2017, 15 pages. |
EPO Search Report dated Nov. 11, 2015, received in corresponding Application No. 13768938.6, 7 pgs. |
PCT International Search Report and Written Opinion dated Aug. 6, 2013, received in corresponding PCT Application No. PCT/US13/34674,pp. 1-19. |
International Search Report and Written Opinion for International application No. PCT/GB2007/004073, dated Jan. 31, 2008. |
International Search Report and Written Opinion for the International Patent Application No. PCT/US2019/063615, dated May 3, 2020, 16 pages. |
International Preliminary Report on Patentability for the International Patent Application No. PCT/US2018/045155, dated Feb. 13, 2020, 10 pages. |
International Search Report and Written Opinion for the International Patent Application No. PCT/US2019/035756, dated Jul. 31, 2019, 11 pages. |
International Search Report and Written Opinion for the International Patent Application No. PCT/US2021/055581, dated Feb. 8, 2022, 19 pages. |
International Search Report and Written Opinion for the International Patent Application No. PCT/US2022/011356, dated Apr. 29, 2022, 19 pages. |
International Search Report and Written Opinion, Application No. PCT/US2022/016713, dated Aug. 5, 2022, 19 pages. |
Number | Date | Country | |
---|---|---|---|
20200164143 A1 | May 2020 | US |
Number | Date | Country | |
---|---|---|---|
62772547 | Nov 2018 | US |