The present invention relates to a drug dispensing device.
The automated systems for preparing pillboxes currently available on the market are installed in pharmacies. There are a number of reasons for this.
All these constraints, together with the requirements of the practices and regulations, do not make it possible to prepare pillboxes, even within care units. In addition, these automated systems utilise single-use packaging for receiving unit drug doses. This packaging is costly and harmful for the environment.
These automated systems do not allow drugs not dispensed, whatever the reason (e.g. prescription changed, patient discharged, or drug recalled by the laboratory that produced it), to be recycled automatically. Lastly, these automated systems do not allow the end-to-end traceability of the dispensing of drugs, from the drugs arriving at the health centre through to delivery to the patient, nor the identification of all the people involved in the dispensing process.
Document WO 2018/157231 describes a system for automatically filling drug organisers, which moves drug containers between a storage unit and temporary storage racks at the same time as the filling process. Document WO 2016/007319 describes a system comprising a drug transport appliance which accommodates a plurality of devices containing drugs. A controller in communication with the appliance generates a first association between a first device containing an accepted drug and a single patient and a second association between a second device containing an accepted drug and a specific type of medical item. Document US 2008/319575 describes a dispensing device in a health institution comprising containers for storing medical supplies, some of the containers being allocated for assignment to patients for storing their drugs and some other supplies.
The present invention aims to remedy all or part of these drawbacks.
To this end, the present invention relates to a device for dispensing a plurality of drugs, according to claim 1.
Thanks to these provisions, there are no longer any consumables, each drawer returning to the storage unit after the drug dose it contained has been dispensed. In addition, a drug dose not dispensed is easily recycled by inserting the drawer containing it into the storage unit, in a passage where drawers including identical drug doses are located. In addition, end-to-end traceability is achieved for the dispensing process because the pillbox comprises the identification of the patient. The risks of error in the preparation, dispensing, administration or dosage are therefore reduced, or even eliminated. Moreover, except for the dispensing trolleys, the device can have the volume of a cabinet, much smaller than the volume of a dedicated room necessary for the preparation devices of the prior state of the art.
In some embodiments, at least one pillbox comprises, with regard to each drawer it comprises, an access hatch for access to the drug dose.
Consequently, the drawers do not need to be pulled out from the pillbox when the drug doses are dispensed to the identified patient. In addition, in the case where a drug dose has not been dispensed, for example because a prescription has been changed, the patient has been discharged, or the drug has been recalled, it is easy to keep it in the drawer that includes it by preventing the door corresponding to this drawer from being opened. The drug dose can therefore be easily re-used for another prescription, to the same or another patient.
In some embodiments, for at least one pillbox at least one hatch is configured to allow the drug dose to be released by gravity. Thanks to these provisions, no manual operation is required to remove the drug dose from of the pillbox.
In some embodiments, at least one hatch is equipped with a bolt preventing or allowing the opening of the hatch.
Thanks to these provisions, access to the drug dose is only possible after authorisation, which ensures traceability of the use of the drug, its presence in the drawer and, possibly, the operator that authorised access to this drug dose.
In some embodiments, the preparation unit comprises a first drawer-holder for inserting a drawer at one end of a passage of a case and a second drawer-holder for pulling out a drawer including a drug dose that has been pushed to the end of this passage, and inserting this removed drawer into one end of a pillbox, the first drawer-holder being configured to pull out a drawer of the pillbox pushed to the other end of the pillbox.
In this way, each passage of each case and each passage of the pillbox always comprises a constant number of drawers. In addition, a computer system can keep in memory, at all times, the location of each drug dose and each drawer.
In some embodiments, each case is equipped, at each end of the passage, with a bolt preventing or allowing the pulling out of the drawer closest to this end.
In some embodiments, each pillbox is equipped, at each end of the passage, with a bolt preventing or allowing the pulling out of the drawer closest to this end.
Thanks to each of these provisions, a drug dose cannot be put into a case and/or a pillbox or taken out of a case and/or pillbox until at least one bolt has been unlocked by the device.
In some embodiments, at least one bolt is magnetic. Thanks to these provisions, the bolts are passive, so that bringing a magnet near or controlling an electromagnet outside the case or pillbox is sufficient to control a bolt.
In some embodiments, the passage of a pillbox comprises as many drawers as each passage of a case. Handling of the drawers pulled out of the cases or pillboxes is thus made easier.
In some embodiments, the device that is the subject of the invention comprises at least one dispensing trolley comprising a plurality of holders of pillboxes, a means for displaying drug doses in a pillbox, means for unlocking a bolt for the hatches of a pillbox, and a means for receiving the content of each drawer for which a hatch has been opened.
In some embodiments, the device comprises a memory of prescriptions and recalls of drug doses, and means for verifying the compliance of the dispensing of each drug dose to a patient with a prescription associated to the patient and for verifying that the drug dose to be dispensed is not the subject of a recall, the verification means being configured to inhibit the unlocking of a hatch if at least one of the verifications gives a negative result. This therefore prevents a drug dose from being dispensed to a patient if it is not the time for taking this drug dose or if this drug dose has been recalled.
In some embodiments, each case and each pillbox bears a unique identifier, the device comprising a memory of the contents of each case and each pillbox. Thanks to these provisions, the device knows, at all times, where each drug dose is located.
In some embodiments, each drawer has an overall rectangular parallelepiped shape whose largest side has a dimension between 40 mm and 60 mm.
The inventors have determined that this shape and this dimension of the drawer mean that more than nine out of ten drug doses dispensed in health institutions in France can fit into the drawers of the device.
Other advantages, aims and particular features of the invention will become apparent from the non-limiting description that follows of at least one particular embodiment of the device that is the subject of the present invention, with reference to drawings included in an appendix, wherein:
The present description is given in a non-limiting way, in which each characteristic of an embodiment can be combined with any other characteristic of any other embodiment in an advantageous way.
Throughout the description, the term “upper” or “top” refers to the normal configuration of use. The notions of vertical and horizontal flow from these definitions.
The device that is the subject of the invention concerns an automated solution for preparing and dispensing drug doses (for example, tablet, capsule or dry by mouth) in a health institution (or “HI”). This solution is modular, i.e. it is comprised of several mechanical and mechatronic elements that interact together. This modularity makes it possible to adapt to the specific requirements of each institution, for example a clinic, hospital or care home for dependent elderly people.
In general, the device for dispensing drug doses that is the subject of the invention comprises, for each drug dose, a drawer configured to accommodate a single dose of any of the drugs dispensed by this device. An example of a drawer is illustrated in
The device comprises a storage unit, or preparation cabinet, shown in
The device also comprises a unit, shown in
In the embodiment of the device that is the subject of the invention shown in the figures, this device comprises three docks, each in a separate location:
The drugs marketed by the pharmaceutical industry vary in shape and size. Their handling is therefore difficult to automate. To enable automation, the present invention standardises each drug dose by cutting up the drug packs and over-packaging them with a reusable overpack, called a “drawer”, an example of which is shown, in perspective, in
Access to drug doses is preferably secured throughout the dispensing process. In effect, preferably, only the three docks mentioned above are able to unlock access to drug doses.
In some embodiments, each drawer 30 has an overall rectangular parallelepiped shape whose largest side has a dimension between 40 mm and 60 mm. The inventors have determined that this shape and this dimension of the drawers 30 mean that more than nine out of ten drug doses dispensed in health institutions in France can fit into the drawers 30.
To facilitate the traceability of these doses in the process, the capacity of a drawer 30 is limited to one drug dose. The sizing of this drawer 30 is optimised based on a metrological study of the composition of the drug formulary of several institutions. Taking into consideration the volumes to be managed (e.g. 6000 doses a week for an institution with 60 patients), these doses, and therefore the drawers, are grouped into a “case” 40 comprising thirty drawers 30 in three superimposed passages. This has the advantage of facilitating the human operations in the logistical phases, and also the mechatronic operations in the treatment preparation dock 60. The case 40 also enables the technical simplification of the design of the drawer 30. In effect, the drawer 30 is closed to prevent manual access to the doses. The provision of a case 40 makes it technically possible to transfer the closure system from the drawer 30 to the case 40, which results in reducing the number of bolts required by a factor of five (six for the six ends of the passages instead of 30 for that number of drawers), which lessens the risk of failure. This system of bolts 42 prevents the drawers 30 from sliding out of the case 40, for example when the case 40 is inclined or handled. The case 40 interacts with the filling dock and the treatment preparation dock 60. A case 40 shown in
In an alternate to the uniformity of the drug doses contained in the drawers 30 of a case 40, for example for drugs dispensed less frequently, the drawers 30 of the same passage each contain an identical unit dose of the same drug but the drawers 30 of different passages of the same case 40 can each contain a different unit dose and/or a different drug.
The pillbox 50, shown in
Like the case 40, the pillbox 50 is equipped with a system of two bolts 52 (one at each end of the passage), preventing the drawers 30 held by a housing 51 from being pulled out.
The access hatches 53 enable the opening of the drawers 30, and therefore access to the unit drug doses contained therein, by the dispensing dock 80.
Preferably, for at least one pillbox 50 at least one hatch 53 is configured to allow the drug dose 23 to 28 to be released by gravity. In other embodiments, the opening of the hatch 53 gives the operator or an extraction mechanism access to the unit dose contained in the drawer 30.
Preferably, at least one hatch 53 is equipped with a bolt preventing or allowing the opening of the hatch 53. In other embodiments, no hatch 53 is equipped with such a bolt.
A slot 46 or 55 comprises a metal plate, enabling the case 40 and pillbox 50 to stick magnetically to magnets of the treatment preparation cabinet 70. This device makes it possible to ensure the proper alignment of the cases 40 and pillboxes 50 in the preparation cabinet 70 and prevents gripping by an operator with bare hands. To carry out the function of dispensing drugs at the level of the dispensing dock 80, it is provided with access hatches 53, also secured by bolts.
In some embodiments, at least one of the bolts described above is magnetic, so that bringing a predefined pole of a magnet near or switching on an electromagnet results in the unlocking of this bolt.
The filling dock (not shown) helps the operator in the phase of filling the cases 40. A possible separation of the drugs is carried out manually or in an automated way. The filling dock is an electromechanical element that:
Software means guide the operator in the phase of identifying the drug, filling the drawers 30 and cases 40, and traceability.
Equipment means of the dock for filling cases comprise:
The treatment preparation dock 60 is an automaton whose main function is the preparation of the pillboxes 50 of patients of the health institution.
The treatment preparation dock 60 in pillboxes 50 works in substantially the same way as a public beverage dispenser equipped with a Cartesian arm (two axes, X and Y) that collects the beverages.
The preparation cabinet 60 of the device that is the subject of the invention has, however, significant differences. This is because, in the beverage dispensers, there is one actuator per product to be distributed (Archimedes screw, belt conveyor). In contrast, in the treatment preparation cabinet 70, because there is a very large number of dispensing passages (in
In some preferred embodiments, such as that shown in
For the transfer of drawers 30 including the drug doses corresponding to the prescription for a patient, from the cases 40 to the pillboxes 50, and vice versa during the recycling of doses not dispensed, an endless loop principle is used. In this way, the empty drawers 30 are used as a stroke extension of an actuator piston associated to the drawer-holders 61 or 62 carried by the arms 65 and 66.
Therefore, the cases 40 and pillboxes 50 are always completely filled with empty or full drawers such that the stroke extension is constant.
The system for transferring drugs is shown schematically, with arrows illustrating the movements of the drawer-holders and drawers, in
After it has been filled, the pillbox 50 includes different drug doses 23 to 28 (except where a prescription specifies taking several identical drug doses at the same time).
The bolts 42 or 52 comprise two magnets that repel each other (inserted into the two rectangles). In this way they allow the bottom portion of the bolt 42 or 52 to remain raised by default. This bottom portion fits into the slot 34 of the drawer.
Each drawer-holder 61 and 62 comprises a side magnet 69 mounted to repel the magnet of the bolt 42 or 52. Being positioned on either side of a passage of a case 40 or a pillbox 50, the two drawer-holders 61 and 62, mirrored, unlock the bolt 42 or 52, at each end of the passage, thus enabling the free movement of drawers in this passage of a case 40 or pillbox 50.
A Cartesian gantry comprises two vertical arms 65 and 66 mounted on guide rails 63 and 64, and moving on these rails by means of motorised toothed wheels 67 and 68. The drawer-holders 61 and 62 move vertically, along tool-arms 65 and 66 respectively.
Each drawer-holder 61 or 62 is, preferably, equipped with a certain number of tools (not shown), for example:
The upper 71 and lower 73 areas contain cases 40. The central area 72 contains pillboxes 50.
In some embodiments, and preferably, the treatment preparation cabinet 70:
The cabinet 70 ensures a preparation capacity of about 100 pillboxes, an autonomy in drugs of at least one week, i.e. about 7000 doses, and a diversity of about 210 medical molecules.
With regard to the dispensing dock, drugs are dispensed, in the vast majority of cases, by means of a care trolley. In an alternate, a fixed dispensing dock is positioned in the health institution.
The computer, electronic and electromechanical system of the dispensing dock 80 controls all the functions of the dock 80, i.e. the opening of the hatches 53 of pillboxes 50, the opening of boxes 83 and the opening of tilt bins 84. This is an electromechanical system controlled by a miniature personal computer, or tablet, 85, an electronic controller (not shown), and a touch screen 90 incorporated into the dispensing dock 80.
The dispensing module 81, shown here fixed in the dispensing dock 80, is preferably incorporated into a drawer of the dispensing dock 80, which makes it possible, when this drawer is pulled out, to reveal the touch screen 90 and the area in which to insert the pillbox 50.
With regard to the general operating principle of the dispensing dock 80 shown in
The dispensing module 81 then displays, on the touch screen 90, the treatments to be dispensed at the current time:
The control of the hatches of the pillbox 50 involves, at the level of the dispensing module 81, a system of actuators, simple and not consuming much energy. Thus a gravitational dispensing system is utilised in which the pillbox 50 has one hatch 53 for each drawer 30. This hatch can only be actuated in the dispensing module 81, by means of an actuator (not shown), for example an electromagnet, as shown in
A means 86 for receiving the contents of each drawer whose hatch 53 has been opened is located below the dispensing module 81. For example, the reception means 86 has a curved surface forming a chute on which the drug doses released by the hatches 53 slide.
The drugs supplied by the pharmaceutical industry are not always identifiable if they are separated into unit doses. In some embodiments, the dispensing dock 80 provides an additional function of physically identifying the drugs contained in each pillbox 50. Thus, the position of the touch screen 90 facing the pillbox 50 enables drugs contained in each drawer 30 to be identified. As shown in
Thanks to the connection of the dispensing module 81 to the health institution's in-house software system real-time knowledge of prescription changes), this module 81 can block certain drug doses in a pillbox 50, for different reasons such as an interruption in treatment or the withdrawal or recall of a batch of drug doses, for example, or when it is not the time to administer a drug dose to a patient. In the latter case, a visual, audible or digital alarm (e.g. on the screen of the computer 85) informs the nurse that she must come back at the time specified by the prescription, for dispensing the drug dose blocked in the pillbox 50.
To further improve the decision-making of the nurse, an area 88 is added on the touch screen 90 for assisting the administration (identification photo of the pill or capsule, of the pack, administration assistance notice, pictograph, ½ or ¾ pill, etc.).
Lastly, the dispensing dock 80 ensures the traceability of the dispensing of drug doses. This traceability has two aspects:
With regard to controlling the opening of personalised boxes 83, in the same way as for the pillboxes 50, when a drug is clicked on in the non-pillbox area 89, the hatch of the box 83, in which the product in question is stored, is unlocked, as shown in
The operating principle of the tilt bins 84 is identical to that of the boxes 83, as shown in
In the variant shown in
The access hatches 57 enable the opening of the drawers 30, and therefore access to the unit drug doses contained therein, by the dispensing dock 80.
Preferably, for at least one pillbox 56 at least one hatch 57 is configured to allow the drug dose 23 to 28 to be released by gravity. In other embodiments, the opening of the hatch 57 gives the operator or an extraction mechanism access to the unit dose contained in the drawer 30.
Preferably, at least one hatch 57 is equipped with a bolt 59 preventing or allowing the opening of the hatch 53. For example, locking means 59, preferably magnetic, keep the hatches 56 closed until they receive unlock commands, for example by bringing a predefined pole of a magnet near or switching on an electromagnet.
In other embodiments, no hatch 57 is equipped with such a bolt.
As can be seen by reading the description above, the device for dispensing a plurality of drugs that is the subject of the invention comprises, for each drug dose of said plurality of drugs, a drawer configured to accommodate a single dose of any of the drugs of said plurality of drugs. This device also comprises a storage unit comprising cases, each case comprising at least one passage for holding drawers and, in each passage, drawers next to one another, all comprising identical drug doses. This device further comprises a unit for preparing pillboxes that is configured to pull drawers out from the cases of the storage unit and place the pulled-out drawers in a pillbox associated with a patient's identifier, the pillbox comprising a passage for holding the drawers that have been placed therein.
Preferably, the device that is the subject of the invention comprises a memory of prescriptions and recalls of drug doses, and software means for verifying the compliance of the dispensing of each drug dose to a patient with a prescription associated to the patient and for verifying that the drug dose to be dispensed is not the subject of a recall. This verification means is configured to inhibit the unlocking of a hatch 53 if at least one of the verifications gives a negative result for the drug dose contained in the drawer 30 associated to this hatch 53.
Each case 40 and each pillbox 50 preferably bears a unique identifier (character string, barcode or electronic tag, for example), the device comprising a memory of the contents of each drawer 30 of each case 40 and each pillbox 50. The software therefore knows, at all times, where each drug dose is located. In some embodiments, each case 40 and each pillbox 50 bears two unique identifiers, one that can be read by a camera and the other in the form of an electronic tag, for example utilising an RFID (acronym for Radio Frequency Identification) or NFC (acronym for Near Field Communication) protocol. Preferably, in this case, the treatment preparation cabinet 70 comprises a space in which a case 40 or pillbox 50 can be positioned so that its two identifiers are read at the same time and these identifiers are associated in the device's memory.
Number | Date | Country | Kind |
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2112839 | Dec 2021 | FR | national |
2114500 | Dec 2021 | FR | national |
Filing Document | Filing Date | Country | Kind |
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PCT/EP2022/084256 | 12/2/2022 | WO |