The present invention relates generally to computer systems and more particularly to data structures for modeling and scoring risk assessment, such as insurance risk.
In the insurance industry and in other fields in which risk is assessed (including such diverse fields as medical treatment, financial modeling and portfolio management, and environmental impact regulation), it is known to develop and use a risk-assessment model of a population. The risk-assessment model provides a technique for determining which population members are more subject or less subject to particular risks (or to an aggregate of risks) than the norm for that population. For example, in life insurance underwriting, it is known to evaluate past and present medical data so as to determine what insurance premium the underwriter wishes to charge.
While these known methods generally achieve the goal of assessing risk for particular individuals in comparison to a population norm, they have the drawback of making a risk assessment that is fixed at a particular point in time. That is, these risk-assessment models rely on static data, in particular (1) static data about the individual population member, (2) static data about the population norm, and (3) static data about risks associated or correlated with the data about the individual population member. However, risk for individual population members depends not only on their present data, but also on their future data, including both data about behavior and environment.
A first type of problem for the known art includes those individuals that have a progressive disease or degenerative condition, in which the disease or condition progresses at a rate that is responsive to behavior or environment of the individual. For such individuals, risk is more accurately evaluated as a function of behavior measured over time and environment measured over time, rather than as a static value that is a function only of present behavior and environment. For example, a first patient with diabetes can proceed with relatively small risk if that first patient is aware of and active in management of behavioral and environmental risk factors. In contrast, an otherwise identical second patient will have significantly greater risk if that second patient is either unaware of, or unable or unwilling to take charge of, behavioral and environmental risk factors.
Related to this first type of problem is the problem of determining trends for individual risk-assessment. For example, an individual with a history of diabetes may suffer a significant increase or decrease in effects thereof, due at least in part to that patient's actions with regard to behavioral and environmental risk factors. Similarly to the first type of problem, that individual will be rationally assessed a significantly greater or lesser risk than originally, if the new facts were known to the underwriter. Such trends may differ significantly from any trends that might have been discerned from past medical history alone; such trends may also themselves involve genetic, environmental, or behavioral components, or some combination thereof.
A second type of problem for the known art includes individuals whose risk-assessment significantly changes due to the vicissitudes of their life trajectory. This can include progression of a disease or condition, responsive at least in part to behavioral or environmental factors. For a more striking example, an individual may suffer a myocardial infarction, or become infected with an HIV variant. Similarly to the first type of problem, that individual would be rationally assessed a significantly greater risk than originally, if the new facts were known to the underwriter. Alternatively, an individual may be successfully treated for a “curable” disease such as Hodgkin's disease or some forms of cancer. Such vicissitudes of life trajectory may themselves involve genetic, environmental, or behavioral components, or some combination thereof.
A third type of problem for the known art includes individuals who significantly change their behavior or environment, particularly when those individuals are susceptible to the elements of their behavior or environment they change. For example, an individual with diabetes can determine to alter their diet favorably or unfavorably. For a more striking example, an individual may take up smoking or skydiving as habits. That individual will become a significantly greater risk than the underwriter originally assessed.
Moreover, new medical research may indicate risk factors that were not known at the time risk for the individual was originally assessed. These could include past medical information not known at the time to be important, tests available in the future for risk factors not known at the time at all, or changes in the medical history of the individual that place that individual in different risk factor categories. Such past medical information or risk factors may themselves involve genetic, environmental, or behavioral elements, or some combination thereof.
Accordingly, it would be advantageous to collect feedback from individual population members, whether on a periodic or aperiodic basis, and whether prompted by selected events or not. Such feedback would allow underwriters or other risk-assessment or risk-management personnel to determine specific risk-related information about each individual population member, and to adjust (such as to make more accurate or precise) insurance models and risk-assessment models to fit the new data. Such feedback enables the advantage of providing information about the time-varying nature of individual measures which can be used in the dynamic risk assessment model presented in the present invention. For instance, a weight gain of 10 pounds per year, an increase in diastolic blood pressure of 10 points per year, and an increase of cholesterol of 10 points per year could be tracked over time and would yield health risk information.
To achieve this advantage, a first aspect of the invention is that feedback is collected by a client-server system in which data is requested or required from population members. A server device, responsive to a risk-assessment model, prompts a client device supplied to population members to request information from population members, in order to determine whether aggregate measures or individual measures of risk-assessment remain in coherence with the model. The client device collects the data and supplies it to the server device, which can, in response to dynamically collected data, adjust the model, adjust risk assessments for selected population members (or groups thereof), or determine further information to collect from population members.
Upon achieving this advantage, a second aspect of the invention is to provide a set of superior risk-assessment models and insurance models in response to the feedback. These superior risk-assessment models and insurance models can include information about the risk-related behavior, risk-related trends, or forward-looking risk-assessment of selected individuals or selected subsets of the population. These superior risk-assessment models and insurance models can be responsive to data-mining techniques described in related patent applications, described below, hereby incorporated by reference as if fully set forth herein. These superior risk-assessment models can also incorporate known scientific information regarding health risk or disease progression, such as well-determined correlations of risk factors and disease incidence or progression from large research studies, or well-known shape of 5-year survival curves for patients having specific types of cancer.
Accordingly, it would also be advantageous to provide a set of techniques for modeling and scoring risk-assessment and a set of insurance products derived therefrom, using dynamic assessment of risk indicators and associated consequences for a population. This advantage is achieved in an embodiment of the invention in which a population (such as a population of medical patients) is assessed both at a selected time and afterward for those risk indicators and for consequences associated therewith. A client-server system provides dynamic data collection and analysis, dynamic risk assessment in response to that data collection and analysis, and dynamic treatment options and utilization review for each population member.
The invention provides a set of techniques for modeling and scoring risk-assessment and a set of insurance products derived therefrom. A set of risk indicators (such as medical risk factors for individuals) is determined at a selected time. A population (such as a population of medical patients) is assessed at the selected time and afterward for those risk indicators and for consequences associated therewith. For example, the population can be periodically assessed for correlation between smoking and heart disease, for correlation between alcohol use and heart disease, and for multivariate correlation of a plurality of such indicators and consequences.
In a preferred embodiment, selected population members are each coupled to client devices for determining risk indicators and consequences. For example, where the population is a set of medical patients, the client device can include a local device for asking medical, psychological and life-style questions, and for measurement of medical parameters, for each of those patients. A server device receives data from each client device, and in response thereto, can (1) reassess weights assigned to the risk indicators, (2) determine new significant risk indicators, (3) determine new significant measures for determining risk indicators and consequences, and (4) present treatment options to each population, member. The server device can perform these tasks in conjunction with an operator, such as a skilled medical professional, risk-management assessor, or other expert.
The server device can determine, in response to the data from each client device, and possibly in response to other data (such as provided by the expert operator), a measure of risk for each indicated consequence or for a set of such consequences. The server device can provide this measure with regard to each population member, or with regard to population subsets (selected either with regard to the known risk indicators or other indicators). The expert operator can use this measure to determine either (1) an individual course of treatment, (2) a resource utilization review model, (3) a risk-assessment model, or (4) an insurance pricing model, for each individual population member or for selected population subsets.
In a preferred embodiment, information requested by the client device, information determined and presented by the server device, and measurements determined in response thereto, can be adapted dynamically to changing aspects or changing membership of the population, or of an external environment having relevance to the population. For example, medical treatment or risk-assessment models can be dynamically adapted to an aging population or to biomedical advances with regard to detection or treatment of medical conditions for members of that population.
a shows a block diagram of a system for data collection and interpretation for a population.
a shows a process flow diagram of a method for dynamic data collection to be performed by the system; verification of model, updating a model, or creating a new model, and re-evaluation of risk assessment.
a shows a process flow diagram of a method for dynamic data analysis to be performed by the system.
In the following description, a preferred embodiment of the invention is described with regard to preferred process steps and data structures. Embodiments of the invention can be implemented using general purpose processors or special purpose processors operating under program control, or other circuits, adapted to particular process steps and data structures described herein. Implementation of the process steps and data structures described herein would not require-undue experimentation or further invention.
System for Data Collection
a shows a block diagram of a system for data collection and interpretation for a population. Referring to
Referring to
The output element 112 includes a display screen 114, on which questions and suggested answers can be displayed for the patient 111, so as to facilitate information entry, or on which instructions can be displayed for the patient 111, so as to instruct the patient 111. The output element 112 can also include a speaker 115, so as to present information in conjunction with or in alternative to the display screen 114. The output element 112 can also include a bell or other sound element, or a bright light 119 or a flag, so as to alert the patient 111 that the client device 110 has questions or information for the patient 111.
The input element 113 includes a plurality of buttons 116A-D for entering information, preferably such as described in the patent applications referenced and incorporated by reference above.
The input element 113 can also include one or more data ports 117A-D for entering information from other devices. Referring to
Such other devices 118 can also include a general purpose or special purpose client workstation, such as a personal computer or a hand-held digital calendar.
The server device 120 is disposed logically remotely from the patient 111, and includes a database 121 of information about the patient 111 and about other patients in a related population thereof. As used herein, “remotely” refers to a logical relationship to the patient 111, and does not have any necessary implication with regard to actual physical position.
The server 120 and patient profile database 121 are preferably accessible by means of a standard network connection such as a world wide web connection. Server 120 and database 121 may comprise single stand-alone computers or multiple computers distributed throughout a network.
Referring to
The data review element 130 is preferably a personal computer, remote terminal, web TV unit, Palm Pilot unit, interactive voice response system, or any other communication technique. The data review element functions as a remote interlace for entering in server 120 or client device 110 messages and queries to be communicated to the individuals.
Aggregate Responses to Risk Indicators
A diagram 200a includes a first axis X 201 and a second axis Y 202. The diagram shows a first response curve RO 210 showing a normal trajectory for vital function and life expectancy of an individual or subpopulation of the population. The first axis X 201 indicates a relative time, as measured toward a right side of the diagram. The scale of the first axis X 201 is a relative time whose initial left hand point may be undetermined. As to a first response curve RO 210, the second axis Y 202 represents a measure of vital function and life expectancy.
A diagram 200a also shows a second response curve SO 220 showing a normal trajectory for a measure of expected medical expense or risk for an individual or subpopulation of the population. The first axis X 201 indicates a relative time as for a first response curve RO 210. As to a second response curve SO 220, the second axis Y 202 shows increasing expense or risk as measured toward the top of the diagram.
In the first response curve RO 210, the normal trajectory for vital function and life expectancy for a typical individual in the population shows that as time progresses, vitality and life expectancy are expected to decrease. This general concept is known in the art of actuaries. It is to be noted that the shape shown by the first response curve RO 210 is an example shape; for instance, it is known that for certain curable cancers, risk increases, then levels off after a certain length of time such as a 5-year survival rate, then later in life risk increases due to other causes.
The first response curve RO 210 includes a number of points with error bars 211 about the response curve RO 210. All of the points 211 are at an identical value, VO, of the second axis Y 202, with identical error bars. Any one of the points represents a single measurement of vitality taken for an individual. Given any single measurement of vitality, it is difficult to determine where along the second axis X 201, that is, where along the trajectory the individual is. Of particular interest is how close to a rapid decline in vitality or increase in risk the individual is. The points 211 show the several places along the curve where the individual might be placed, based on this single measurement of vitality. Because the response curve RO 210 is slowly varying through much of the time, that is, the values of vitality and life expectancy clustering in a selected region of the second axis Y 202, shown by the bracket 203, and due to margins of error in both the measurement as well as the response curve, there are several positions along the curve where an individual with a specific measurement might be; these several positions are shown by points 211.
By contrast, if measurements are taken for an individual at more than one point in time, greater information is present, and in particular trends may be discerned which yield more information about where on the curve an individual is. This ability to discern trends is greater when curves in N-dimensions are considered. For instance, an individual whose excess weight has slowly climbed in conjunction with slowly increasing cholesterol, blood pressure, stress levels and family medical history would be placed in a greater risk category although the individual measures of, for instance, cholesterol, might be within a normal range.
Similarly, in the second response curve SO 220, the normal trajectory for expected medical expense and risk for that typical individual shows that as time progresses, expected medical expense and risk are expected to increase. This general concept is also known in the art of actuaries. It is to be noted that the shape shown by the second response curve RO 220 is an example shape; for instance, upon diagnosis of a disease the expense may climb, but if the patient is cured the expense will level off.
Similarly, the second response curve SO 220 includes a number of points 221 on the response curve SO 220, showing possible places that an individual in the population with measurement of expense or risk, with value E0, might be. Because most of the values of response curve SO 220 cluster in a selected region of the second axis Y 202 shown by the bracket 204, it is difficult to know where along curve SO 220 an individual with measurement E0 should be placed. This is due to both possible error in measurement of E0 as well as uncertainty in the exact “true” position and shape of curve SO 220. As for curve RO 210, measurements of expense or risk taken over time will yield useful information about where on the curve SO 220 an individual is.
When subsets of the population are selected in response to specific risk factors, the statistical aggregates of the population can differ substantially from the aggregate response curves RO 210 and SO 220 for the entire population. The diagram 200a shows response curves R1a 212 and R1b 213 showing a normal life trajectory for vital function and life expectancy of an “average” individual in the population, depending on whether that individual is associated with a selected risk factor a. As with regard to the aggregate for the entire population, it is difficult to determine from a specific single measurement just where on either response curve R1a 212 or R1b 213 the individual should be assessed. Depending on whether the value of a is known for an individual, it may also be difficult to know whether the individual should be placed on response curve R1a 212 or R1b 213. Measurements of several risk indicators taken over time may yield information on whether a specific individual should be placed in category R1a 213 or the higher risk category R1b 212. The general concept of using time-dependent information to determine risk along is also illustrated in
The client device 110 determines information from which the server device 120 or the data review element 130 can analyze the time varying nature of data. The server device 120 or the data review element 130 can therefore determine both of the following: (1) just where on either response curve R1a 212 or R1b 213 the individual should be assessed; and (2) whether the individual should be assessed on the response curve R1a 212 or the response curve R1b 213.
It is to be noted that the above analysis has been condensed to 2-dimensions for convenience in presentation, with a single measurement along a single X-axis or Y-axis. In a preferred embodiment, a measurement would have many attributes, i.e. the model would have N-dimensions, and more sophisticated techniques for analyzing trends and achieving objectives are used.
If the data for the population is not known for all individuals in the population or subpopulation of interest, the server device 120 transmits a new set of information-gathering instructions (such as questions and suggested answers) to the client device 110, so as to measure that information individually for each patient 111.
Dynamic Modeling and Risk Evaluation
a shows a process flow diagram 300a for a method with steps of dynamically collecting information 310, choosing to verify or update the model or to create new model 320, verifying 350 or updating 330 the risk assessment model or creating a new model 340, deciding whether to re-evaluate risk 360 and re-evaluating risk based on updated information and current model 370.
Dynamic Data Collection for Population
b shows a process flow diagram 300b of a method for dynamic data collection to be performed by the system. This data collection may be done periodically or aperiodically, upon a triggering event or decision by the expert operator. The population or subpopulation from which to collect data is selected 380. The selection criteria may be based on preset values or may be set by the expert operator. The set of risk indicators or other information to be collected is selected 382, based either on preset values or decision by the expert operator. The individuals in the subpopulation of interest are queried 384 as to the information of interest and the database is updated 386. “The pre-query steps need not be done in the order indicated.
Verification of Existing Model and Update of Model
c shows a process flow diagram 300c of a method by which the updated data can be analyzed to determine whether the existing model is consistent with the updated data; that is, to verify that the data conforms to the model within acceptable variation or error. This is accomplished by putting the updated data into categories 390, determining the updating measures of life vitality or costs 392, determining the values predicted by the model 394, comparing the updated measures of life vitality or costs against those predicted by the model 396. and determining whether the comparison is acceptable 397. If the predicted value is within an acceptable distance from the updated values based on well known measures such as statistical error, then the model need not be adjusted. The expert operator may also visually determine whether the updated data and existing model show an acceptable relationship to each other.
d shows a process flow diagram 300d of a method for updating the existing risk model in response to updated information. By updating, it is meant that no new risk indicators are added, and no new external constraints on the model are added. The risk model to be adjusted may be for the aggregate population or for various subpopulations. The updated information for the subpopulation is categorized 398 according to profile information into one or more existing categories. The subpopulation is categorized according to one or more existing measure of life vitality or medical expense. Statistical analyses as described below or in other patents or patent applications previously incorporated by reference or as known in the art of statistics are applied to determine updated values for model parameters such as weights to give each factor 399
Re-Evaluating Risk Assessment Based on Updated Information
As shown in
Dynamic Data Analysis for Population
a shows a process flow diagram 400a of a method for dynamic data analysis (“data mining”) to be performed by the system. The updated database can be mined to create a new model that may include reassessment of weights assigned to the risk indicators, addition of new significant risk indicators, or determination of new significant measures for determining risk indicators and consequences. Applied examples of data mining and additional explanation are shown in the related application Ser. No. 09/041,809 and other applications referenced above.
b shows a process flow diagram of a method of using the statistical method of calculating correlations on subpopulations, following the steps of: (1) choose a risk factor 450; (2) divide the risk pool into two groups based on outcome 460; (3) search all other data for correlation to high versus low risk 470; (3) create a new risk factor based on this correlation 480. The new risk factor may be a discrete piece of data that was asked of the client but was not previously known to be a significant predictor, or it may be a new factor that is generated by combining other pieces of data.
In addition to data mined from the database, in creating a new model, scientific information well known in the literature may supplement the data. For instance, scientific information regarding certain well studied correlations be considered such as known correlations of time since quitting smoking and various health conditions, known information regarding the shape of life expectancy curves for certain types of cancer patients, or recent information regarding efficacy of new forms of treatment for diseases such as recent significant improvements in treatment of AIDS.
Statistical analyses are known in the art of statistics, and include correlation analyses, multivariate regressions, constrained multivariate regressions, or variance analyses, may also be run on the data to reveal statistical relationships among the various information or measures of life vitality or medical expense in order to improve the predictive power of a model, although in a preferred embodiment data mining is done as presented in the preceding paragraphs.
Modeling and Scoring Risk Assessment, Insurance Pricing
Modeling risk is performed by assigning risk to individual in response to risk factors identified for that individual, and such modeling may be done for the population or for a subpopulation. There are many techniques for modeling, such as linearly risk scoring by assigning a number to each risk factor and adding up each number to determine a total risk score, non-linearly assessing risk by combining risk factors non-linearly to determine risk which may be achieved by neural network techniques which are known in the art of neural networks, or other techniques.
Insurance pricing may be achieved from advantages in risk assessment. It is known in the art of actuarial analysis to assign price in response to risk.
Providing Treatment Options and Information to each Population Member
Although preferred embodiments are disclosed herein, many variations are possible which remain within the concept, scope, and spirit of the invention, and these variations would become clear to those skilled in the art after perusal of this application.
The present application is a continuation of U.S. patent application Ser. No. 09/625,080 filed Jul. 25, 2000, now U.S. Pat. No. 7,305,348 which is a continuation of U.S. patent application Ser. No. 09/160,970 filed Sep. 25, 1998, issued as U.S. Pat. No. 6,240,393. Said U.S. patent application Ser. No. 09/625,080 and U.S. patent application Ser. No. 09/160,970 are hereby incorporated by reference in their entirety. The following applications are hereby incorporated by reference: U.S. patent application Ser. No. 09/159,219 filed Sep. 23, 1998 (abandoned) U.S. patent application Ser. No. 09/159,058 filed Sep. 23, 1998 (abandoned)
Number | Name | Date | Kind |
---|---|---|---|
3426150 | Tygart | Feb 1969 | A |
3566365 | Rawson et al. | Feb 1971 | A |
3566370 | Worthington, Jr. et al. | Feb 1971 | A |
3581072 | Nymeyer | May 1971 | A |
3768014 | Smith | Oct 1973 | A |
3811116 | Takeuchi et al. | May 1974 | A |
3883235 | Lynn et al. | May 1975 | A |
3910257 | Fletcher et al. | Oct 1975 | A |
3920005 | Gombrich et al. | Nov 1975 | A |
3996928 | Marx | Dec 1976 | A |
4004577 | Sarnoff | Jan 1977 | A |
4051522 | Healy et al. | Sep 1977 | A |
4060915 | Conway | Dec 1977 | A |
4130881 | Haessler et al. | Dec 1978 | A |
4150284 | Trenkler et al. | Apr 1979 | A |
4151407 | McBride et al. | Apr 1979 | A |
4151831 | Lester | May 1979 | A |
4173971 | Karz | Nov 1979 | A |
4216462 | McGrath et al. | Aug 1980 | A |
4227526 | Goss | Oct 1980 | A |
4253521 | Savage | Mar 1981 | A |
4259548 | Fahey et al. | Mar 1981 | A |
4270547 | Steffen et al. | Jun 1981 | A |
4296756 | Dunning et al. | Oct 1981 | A |
4347568 | Giguere et al. | Aug 1982 | A |
4347851 | Jundanian | Sep 1982 | A |
4360345 | Hon | Nov 1982 | A |
4412287 | Braddock, III | Oct 1983 | A |
4417306 | Citron et al. | Nov 1983 | A |
4422081 | Woods | Dec 1983 | A |
4428733 | Kumar-Misir | Jan 1984 | A |
4449536 | Weaver | May 1984 | A |
4465077 | Schneider | Aug 1984 | A |
4473884 | Behl | Sep 1984 | A |
4518361 | Conway | May 1985 | A |
4519398 | Lisiecki et al. | May 1985 | A |
4531527 | Reinhold, Jr. | Jul 1985 | A |
4546436 | Schneider et al. | Oct 1985 | A |
4566461 | Lubell et al. | Jan 1986 | A |
4576578 | Parker et al. | Mar 1986 | A |
4592546 | Fascenda et al. | Jun 1986 | A |
4627445 | Garcia | Dec 1986 | A |
4674652 | Aten et al. | Jun 1987 | A |
4686624 | Blum et al. | Aug 1987 | A |
4694490 | Harvey et al. | Sep 1987 | A |
4695954 | Rose et al. | Sep 1987 | A |
4712562 | Ohayon et al. | Dec 1987 | A |
4722349 | Baumberg | Feb 1988 | A |
4729381 | Harada et al. | Mar 1988 | A |
4730253 | Gordon | Mar 1988 | A |
4731726 | Allen, III | Mar 1988 | A |
4738451 | Logg | Apr 1988 | A |
4768229 | Benjamin et al. | Aug 1988 | A |
4779199 | Yoneda et al. | Oct 1988 | A |
4782511 | Nemec et al. | Nov 1988 | A |
4789928 | Fujisaki | Dec 1988 | A |
4796639 | Snow et al. | Jan 1989 | A |
4799156 | Shavit et al. | Jan 1989 | A |
4799199 | Scales, III et al. | Jan 1989 | A |
4803625 | Fu et al. | Feb 1989 | A |
4835372 | Gombrich et al. | May 1989 | A |
4838275 | Lee | Jun 1989 | A |
4846797 | Howson et al. | Jul 1989 | A |
4853521 | Claeys et al. | Aug 1989 | A |
4858354 | Gettler | Aug 1989 | A |
4858617 | Sanders | Aug 1989 | A |
4890621 | Hakky | Jan 1990 | A |
4894777 | Negishi et al. | Jan 1990 | A |
4897869 | Takahashi | Jan 1990 | A |
4899839 | Dessertine et al. | Feb 1990 | A |
4903201 | Wagner | Feb 1990 | A |
4907973 | Hon | Mar 1990 | A |
4931934 | Snyder | Jun 1990 | A |
4933873 | Kaufman et al. | Jun 1990 | A |
4933876 | Markoff et al. | Jun 1990 | A |
4950246 | Muller | Aug 1990 | A |
4950264 | Osborn, III | Aug 1990 | A |
4953552 | DeMarzo | Sep 1990 | A |
4958632 | Duggan | Sep 1990 | A |
4958641 | Digby et al. | Sep 1990 | A |
4967756 | Hewitt | Nov 1990 | A |
4977899 | Digby et al. | Dec 1990 | A |
4978303 | Lampbell | Dec 1990 | A |
4978335 | Arthur, III | Dec 1990 | A |
4979509 | Hakky | Dec 1990 | A |
5007429 | Treatch et al. | Apr 1991 | A |
5009645 | Silver et al. | Apr 1991 | A |
5016172 | Dessertine | May 1991 | A |
5019974 | Beckers | May 1991 | A |
5024225 | Fang | Jun 1991 | A |
5025374 | Roizen et al. | Jun 1991 | A |
5034807 | Von Kohorn | Jul 1991 | A |
5035625 | Munson et al. | Jul 1991 | A |
5036462 | Kaufman et al. | Jul 1991 | A |
5049487 | Phillips et al. | Sep 1991 | A |
5050612 | Matsumura | Sep 1991 | A |
5056059 | Tivig et al. | Oct 1991 | A |
5059394 | Phillips et al. | Oct 1991 | A |
5065315 | Garcia | Nov 1991 | A |
5068536 | Rosenthal | Nov 1991 | A |
5074317 | Bondell et al. | Dec 1991 | A |
5077476 | Rosenthal | Dec 1991 | A |
5077665 | Silverman et al. | Dec 1991 | A |
5095798 | Okada et al. | Mar 1992 | A |
5104380 | Holman et al. | Apr 1992 | A |
5109414 | Harvey et al. | Apr 1992 | A |
5109974 | Beer et al. | May 1992 | A |
5111396 | Mills et al. | May 1992 | A |
5111817 | Clark et al. | May 1992 | A |
5111818 | Suzuki et al. | May 1992 | A |
5120230 | Clark et al. | Jun 1992 | A |
5120421 | Glass et al. | Jun 1992 | A |
5128752 | Von Kohorn | Jul 1992 | A |
5134391 | Okada | Jul 1992 | A |
5142358 | Jason | Aug 1992 | A |
5142484 | Kaufman et al. | Aug 1992 | A |
5143378 | Joel | Sep 1992 | A |
5171977 | Morrison | Dec 1992 | A |
5176502 | Sanderson et al. | Jan 1993 | A |
5182707 | Cooper et al. | Jan 1993 | A |
5204670 | Stinton | Apr 1993 | A |
5219322 | Weathers | Jun 1993 | A |
5222020 | Takeda | Jun 1993 | A |
5226895 | Harris | Jul 1993 | A |
5227874 | Von Kohorn | Jul 1993 | A |
5228450 | Sellers | Jul 1993 | A |
5230629 | Buschke | Jul 1993 | A |
5231990 | Gauglitz | Aug 1993 | A |
5243515 | Lee | Sep 1993 | A |
5249044 | Von Kohorn | Sep 1993 | A |
5251126 | Kahn et al. | Oct 1993 | A |
5261401 | Baker et al. | Nov 1993 | A |
5262943 | Thibado et al. | Nov 1993 | A |
5265888 | Yamamoto et al. | Nov 1993 | A |
5266179 | Nankai et al. | Nov 1993 | A |
5275159 | Griebel | Jan 1994 | A |
5282950 | Dietze et al. | Feb 1994 | A |
5295491 | Gevins | Mar 1994 | A |
5299121 | Brill et al. | Mar 1994 | A |
5301105 | Cummings, Jr. | Apr 1994 | A |
5304112 | Mrklas et al. | Apr 1994 | A |
5304468 | Phillips et al. | Apr 1994 | A |
5307263 | Brown | Apr 1994 | A |
5309919 | Snell et al. | May 1994 | A |
5321009 | Baeder et al. | Jun 1994 | A |
5325288 | Satou | Jun 1994 | A |
5329459 | Kaufman et al. | Jul 1994 | A |
5329608 | Bocchieri et al. | Jul 1994 | A |
5331549 | Crawford, Jr. | Jul 1994 | A |
5333981 | Pronovost et al. | Aug 1994 | A |
5335338 | Proesel | Aug 1994 | A |
5339821 | Fujimoto | Aug 1994 | A |
5341291 | Roizen et al. | Aug 1994 | A |
5343239 | Lappington et al. | Aug 1994 | A |
5344324 | O'Donnell et al. | Sep 1994 | A |
5357427 | Langen et al. | Oct 1994 | A |
5366896 | Margrey et al. | Nov 1994 | A |
5368562 | Blomquist et al. | Nov 1994 | A |
5371687 | Holmes, II et al. | Dec 1994 | A |
5375604 | Kelly et al. | Dec 1994 | A |
5377100 | Pope et al. | Dec 1994 | A |
5390238 | Kirk et al. | Feb 1995 | A |
5399821 | Inagaki et al. | Mar 1995 | A |
5410471 | Alyfuku et al. | Apr 1995 | A |
5410474 | Fox | Apr 1995 | A |
5429140 | Burdea et al. | Jul 1995 | A |
5431690 | Schaldach et al. | Jul 1995 | A |
5431691 | Snell et al. | Jul 1995 | A |
5434611 | Tamura | Jul 1995 | A |
5438607 | Przygoda, Jr. et al. | Aug 1995 | A |
5438983 | Falcon | Aug 1995 | A |
5441047 | David et al. | Aug 1995 | A |
5449334 | Kingsbury | Sep 1995 | A |
5454721 | Kuch | Oct 1995 | A |
5454722 | Holland et al. | Oct 1995 | A |
5456606 | McIntyre | Oct 1995 | A |
5456692 | Smith, Jr. et al. | Oct 1995 | A |
5458123 | Unger | Oct 1995 | A |
5467269 | Flaten | Nov 1995 | A |
5471039 | Irwin, Jr. et al. | Nov 1995 | A |
5471382 | Tallman et al. | Nov 1995 | A |
5483276 | Brooks et al. | Jan 1996 | A |
5488412 | Majeti et al. | Jan 1996 | A |
5488423 | Walkingshaw et al. | Jan 1996 | A |
5501231 | Kaish | Mar 1996 | A |
5502636 | Clarke | Mar 1996 | A |
5502726 | Fischer | Mar 1996 | A |
5504519 | Remillard | Apr 1996 | A |
5517405 | McAndrew et al. | May 1996 | A |
5518001 | Snell | May 1996 | A |
5519058 | Gonick et al. | May 1996 | A |
5519433 | Lappington et al. | May 1996 | A |
5523232 | Sechler | Jun 1996 | A |
5536249 | Castellano et al. | Jul 1996 | A |
5542420 | Goldman et al. | Aug 1996 | A |
5544649 | David et al. | Aug 1996 | A |
5546943 | Gould | Aug 1996 | A |
5549117 | Tacklind et al. | Aug 1996 | A |
5550575 | West et al. | Aug 1996 | A |
5553609 | Chen et al. | Sep 1996 | A |
5558638 | Evers et al. | Sep 1996 | A |
5564429 | Bornn et al. | Oct 1996 | A |
5569212 | Brown | Oct 1996 | A |
5572421 | Altman et al. | Nov 1996 | A |
5572646 | Kawai et al. | Nov 1996 | A |
5574828 | Hayward et al. | Nov 1996 | A |
5576952 | Stutman et al. | Nov 1996 | A |
5583758 | McIlroy et al. | Dec 1996 | A |
5590648 | Mitchell et al. | Jan 1997 | A |
5593349 | Miguel et al. | Jan 1997 | A |
5593390 | Castellano et al. | Jan 1997 | A |
5594637 | Eisenberg et al. | Jan 1997 | A |
5596994 | Bro | Jan 1997 | A |
5597307 | Redford et al. | Jan 1997 | A |
5601435 | Quy | Feb 1997 | A |
5613495 | Mills et al. | Mar 1997 | A |
5619991 | Sloane | Apr 1997 | A |
5624265 | Redford et al. | Apr 1997 | A |
5628309 | Brown | May 1997 | A |
5629981 | Nerlikar | May 1997 | A |
5631844 | Margrey et al. | May 1997 | A |
5633910 | Cohen | May 1997 | A |
5635532 | Samid | Jun 1997 | A |
5639471 | Chait et al. | Jun 1997 | A |
5640569 | Miller et al. | Jun 1997 | A |
5640953 | Bishop et al. | Jun 1997 | A |
5642731 | Kehr | Jul 1997 | A |
5642936 | Evans | Jul 1997 | A |
5651363 | Kaufman et al. | Jul 1997 | A |
5651775 | Walker et al. | Jul 1997 | A |
5659691 | Durward et al. | Aug 1997 | A |
5666487 | Goodman et al. | Sep 1997 | A |
5670711 | Detournay et al. | Sep 1997 | A |
5675635 | Vos et al. | Oct 1997 | A |
5678562 | Sellers | Oct 1997 | A |
5678571 | Brown | Oct 1997 | A |
5679075 | Forrest et al. | Oct 1997 | A |
5680590 | Parti | Oct 1997 | A |
5680866 | Kangas et al. | Oct 1997 | A |
5687322 | Deaton et al. | Nov 1997 | A |
5687717 | Halpern et al. | Nov 1997 | A |
5687734 | Dempsey et al. | Nov 1997 | A |
5689652 | Lupien et al. | Nov 1997 | A |
5692906 | Corder | Dec 1997 | A |
5704364 | Saltzstein et al. | Jan 1998 | A |
5704366 | Tacklind et al. | Jan 1998 | A |
5704902 | Vandenbelt et al. | Jan 1998 | A |
5704922 | Brown | Jan 1998 | A |
5710178 | Samid | Jan 1998 | A |
5710918 | Lagarde et al. | Jan 1998 | A |
5711297 | Iliff | Jan 1998 | A |
5714319 | Joutel et al. | Feb 1998 | A |
5715451 | Marlin | Feb 1998 | A |
5715823 | Wood et al. | Feb 1998 | A |
5717739 | Dyer et al. | Feb 1998 | A |
5717913 | Driscoll | Feb 1998 | A |
5720733 | Brown | Feb 1998 | A |
5722418 | Bro | Mar 1998 | A |
5727153 | Powell | Mar 1998 | A |
5730124 | Yamauchi | Mar 1998 | A |
5730654 | Brown | Mar 1998 | A |
5732696 | Rapoport et al. | Mar 1998 | A |
5732709 | Tacklind et al. | Mar 1998 | A |
5734413 | Lappington et al. | Mar 1998 | A |
5749083 | Koda et al. | May 1998 | A |
5752234 | Withers | May 1998 | A |
5754740 | Fukuoka et al. | May 1998 | A |
5760771 | Blonder et al. | Jun 1998 | A |
5772585 | Lavin et al. | Jun 1998 | A |
5778882 | Raymond et al. | Jul 1998 | A |
5782814 | Brown et al. | Jul 1998 | A |
5785650 | Akasaka et al. | Jul 1998 | A |
5787295 | Nakao | Jul 1998 | A |
5791342 | Woodard | Aug 1998 | A |
5792117 | Brown | Aug 1998 | A |
5793969 | Kamentsky et al. | Aug 1998 | A |
5794219 | Brown | Aug 1998 | A |
5794251 | Watanabe et al. | Aug 1998 | A |
5796393 | MacNaughton et al. | Aug 1998 | A |
5799318 | Cardinal et al. | Aug 1998 | A |
5800458 | Wingrove | Sep 1998 | A |
5802494 | Kuno | Sep 1998 | A |
5802534 | Hatayama et al. | Sep 1998 | A |
5806057 | Gormley et al. | Sep 1998 | A |
5807336 | Russo et al. | Sep 1998 | A |
5810747 | Brudny et al. | Sep 1998 | A |
5819735 | Mansfield et al. | Oct 1998 | A |
5822544 | Chaco et al. | Oct 1998 | A |
5822715 | Worthington et al. | Oct 1998 | A |
5825283 | Camhi | Oct 1998 | A |
5827180 | Goodman | Oct 1998 | A |
5828943 | Brown | Oct 1998 | A |
5832448 | Brown | Nov 1998 | A |
5835896 | Fisher et al. | Nov 1998 | A |
5840020 | Heinonen et al. | Nov 1998 | A |
5842976 | Williamson | Dec 1998 | A |
5868669 | Iliff | Feb 1999 | A |
5868683 | Protopapas et al. | Feb 1999 | A |
5875432 | Sehr | Feb 1999 | A |
5879163 | Brown et al. | Mar 1999 | A |
5882338 | Gray | Mar 1999 | A |
5887133 | Brown et al. | Mar 1999 | A |
5893077 | Griffin | Apr 1999 | A |
5893098 | Peters et al. | Apr 1999 | A |
5897493 | Brown | Apr 1999 | A |
5899855 | Brown | May 1999 | A |
5911687 | Sato et al. | Jun 1999 | A |
5913310 | Brown | Jun 1999 | A |
5913826 | Blank | Jun 1999 | A |
5918603 | Brown | Jul 1999 | A |
5920477 | Hofberg et al. | Jul 1999 | A |
5933136 | Brown | Aug 1999 | A |
5935060 | Iliff | Aug 1999 | A |
5937387 | Summerell et al. | Aug 1999 | A |
5940801 | Brown | Aug 1999 | A |
5940802 | Hildebrand et al. | Aug 1999 | A |
5941829 | Saltzstein et al. | Aug 1999 | A |
5945651 | Chorosinski et al. | Aug 1999 | A |
5951300 | Brown | Sep 1999 | A |
5954641 | Kehr et al. | Sep 1999 | A |
5956501 | Brown | Sep 1999 | A |
5960403 | Brown | Sep 1999 | A |
5961446 | Beller et al. | Oct 1999 | A |
5966526 | Yokoi | Oct 1999 | A |
5971855 | Ng | Oct 1999 | A |
5971922 | Arita et al. | Oct 1999 | A |
5983003 | Lection et al. | Nov 1999 | A |
5983217 | Khosravi-Sichani et al. | Nov 1999 | A |
5987471 | Bodine et al. | Nov 1999 | A |
5995969 | Lee et al. | Nov 1999 | A |
5997476 | Brown | Dec 1999 | A |
5997502 | Reilly et al. | Dec 1999 | A |
6001065 | DeVito | Dec 1999 | A |
6022315 | Iliff | Feb 2000 | A |
6022615 | Rettenbacher | Feb 2000 | A |
6023686 | Brown | Feb 2000 | A |
6024281 | Shepley | Feb 2000 | A |
6024699 | Surwit et al. | Feb 2000 | A |
6029138 | Khorasani et al. | Feb 2000 | A |
6032119 | Brown et al. | Feb 2000 | A |
6035328 | Soukal | Mar 2000 | A |
6046761 | Echerer | Apr 2000 | A |
6049794 | Jacobs et al. | Apr 2000 | A |
6050940 | Braun et al. | Apr 2000 | A |
6055314 | Spies et al. | Apr 2000 | A |
6055487 | Margery et al. | Apr 2000 | A |
6055506 | Frasca, Jr. | Apr 2000 | A |
6057758 | Dempsey et al. | May 2000 | A |
6068615 | Brown et al. | May 2000 | A |
6101478 | Brown | Aug 2000 | A |
6110148 | Brown et al. | Aug 2000 | A |
6113578 | Brown | Sep 2000 | A |
6138145 | Kawanaka | Oct 2000 | A |
6144837 | Quy | Nov 2000 | A |
6151586 | Brown | Nov 2000 | A |
6161095 | Brown | Dec 2000 | A |
6167362 | Brown et al. | Dec 2000 | A |
6167386 | Brown | Dec 2000 | A |
6168563 | Brown | Jan 2001 | B1 |
6177940 | Bond et al. | Jan 2001 | B1 |
6186145 | Brown | Feb 2001 | B1 |
6189029 | Fuerst | Feb 2001 | B1 |
D439242 | Brown et al. | Mar 2001 | S |
6210272 | Brown | Apr 2001 | B1 |
6221012 | Maschke et al. | Apr 2001 | B1 |
6233539 | Brown | May 2001 | B1 |
6240393 | Brown | May 2001 | B1 |
6246992 | Brown | Jun 2001 | B1 |
6248065 | Brown | Jun 2001 | B1 |
6260022 | Brown | Jul 2001 | B1 |
6270455 | Brown | Aug 2001 | B1 |
6270456 | Iliff | Aug 2001 | B1 |
6334778 | Brown | Jan 2002 | B1 |
6352523 | Brown et al. | Mar 2002 | B1 |
6368273 | Brown | Apr 2002 | B1 |
6370513 | Kolawa et al. | Apr 2002 | B1 |
6375469 | Brown | Apr 2002 | B1 |
6379301 | Worthington et al. | Apr 2002 | B1 |
6381577 | Griffin | Apr 2002 | B1 |
6436036 | Miller-Kovach et al. | Aug 2002 | B1 |
6513532 | Mault et al. | Feb 2003 | B2 |
20020019748 | Brown | Feb 2002 | A1 |
20040106855 | Brown | Jun 2004 | A1 |
20040107116 | Brown | Jun 2004 | A1 |
20040117207 | Brown | Jun 2004 | A1 |
20040117208 | Brown | Jun 2004 | A1 |
20040117209 | Brown | Jun 2004 | A1 |
20040117210 | Brown | Jun 2004 | A1 |
Number | Date | Country |
---|---|---|
0286456 | Oct 1988 | EP |
0320749 | Jun 1989 | EP |
370599 | May 1990 | EP |
0461910 | Dec 1991 | EP |
508912 | Oct 1992 | EP |
526166 | Feb 1993 | EP |
0558975 | Sep 1993 | EP |
0653718 | May 1995 | EP |
676709 | Oct 1995 | EP |
680727 | Nov 1995 | EP |
761160 | Mar 1997 | EP |
08131551 | Dec 1997 | EP |
0251520 | Jan 1998 | EP |
2218831 | Nov 1989 | GB |
2225637 | Jun 1990 | GB |
54005785 | Jan 1979 | JP |
54146633 | Nov 1979 | JP |
62226278 | Oct 1987 | JP |
5155024 | Jun 1993 | JP |
5266002 | Oct 1993 | JP |
WO-8501667 | Apr 1985 | WO |
WO-9000367 | Jan 1990 | WO |
WO-9109374 | Jun 1991 | WO |
WO-9301489 | Jan 1993 | WO |
WO-9416774 | Aug 1994 | WO |
WO-9509386 | Apr 1995 | WO |
WO-9520199 | Jul 1995 | WO |
WO-9522131 | Aug 1995 | WO |
WO-9529447 | Nov 1995 | WO |
WO-9607908 | Mar 1996 | WO |
WO-9625877 | Aug 1996 | WO |
WO-9636923 | Nov 1996 | WO |
WO-9708605 | Mar 1997 | WO |
WO-9712544 | Apr 1997 | WO |
WO-9737738 | Oct 1997 | WO |
WO-9816895 | Apr 1998 | WO |
Number | Date | Country | |
---|---|---|---|
20080046268 A1 | Feb 2008 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 09625080 | Jul 2000 | US |
Child | 11835593 | US | |
Parent | 09160970 | Sep 1998 | US |
Child | 09625080 | US |