Claims
- 1. A pharmaceutical composition for delivery from an osmotic dosage form for administering an antiepileptic drug in the gastrointestinal tract having a pH of 1 to 8 of a patient, comprising 0.5 wt % to 90 wt % of an antiepileptic drug, and a pharmaceutically acceptable carrier comprising 10 wt % to 75 wt % of a carboxymethylcellulose, and 0.1 wt % to 25 wt % of a polyvinylpyrrolidone, said pharmaceutical composition when administered orally from the osmotic dosage form comprising means for protecting the antiepileptic drug from the gastrointestinal tract pH of 1 to 8, releases a dose of antiepileptic drug to the patient for providing an antiepileptic level in the blood as a function of the osmotic dosage form which lessens the incidence of epilepsy.
Parent Case Info
This application is a division of application Ser. No. 08/234,092, filed Apr. 18, 1994, and benefit of the filing date of said earlier filed application is claimed under 35 U.S.C. .sctn. 120.
US Referenced Citations (23)
Foreign Referenced Citations (1)
Number |
Date |
Country |
0439858 |
Aug 1991 |
EPX |
Non-Patent Literature Citations (4)
Entry |
Copy of Abstract of Tukker "Substained Release Phenytoin Veterinary Comps.--Comprises Phenytoin or a Sodium Salt Opt with a Gel Former". (1991). |
Wurster, Dale E., "Preparation of Compressed Tablet Granulations by the Air-Suspension Technique II*" J. of the Amer. Phar. Assoc. vol. 49, No. 2, Feb. 1960. |
Wurster, Dale E., "Air-Suspension Technique of Coating Drug Particles*" J. Amer. Phar. Assoc. Sci. Ed. vol. 48, Aug. 1959. |
Remington's Phar. Sci., 14th Ed. pp. 1626-1680, Felmeister, Alvin (1969). |
Divisions (1)
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Number |
Date |
Country |
Parent |
234092 |
Apr 1994 |
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