Efficacy Testing of a Culturally Relevant Stigma Intervention in WLWH in Tanzania

Information

  • Research Project
  • 10301200
  • ApplicationId
    10301200
  • Core Project Number
    R21TW012007
  • Full Project Number
    1R21TW012007-01
  • Serial Number
    012007
  • FOA Number
    PAR-19-326
  • Sub Project Id
  • Project Start Date
    9/17/2021 - 4 years ago
  • Project End Date
    5/31/2023 - 2 years ago
  • Program Officer Name
    BANSAL, GEETHA PARTHASARATHY
  • Budget Start Date
    9/17/2021 - 4 years ago
  • Budget End Date
    5/31/2022 - 3 years ago
  • Fiscal Year
    2021
  • Support Year
    01
  • Suffix
  • Award Notice Date
    9/15/2021 - 4 years ago
Organizations

Efficacy Testing of a Culturally Relevant Stigma Intervention in WLWH in Tanzania

ABSTRACT/PROJECT SUMMARY HIV-related stigma, especially internalized stigma, yields several negative outcomes. According to UNAIDS, only 62% of Tanzanians living with HIV are virologically suppressed, with gender inequality and HIV-related stigma acting as major barriers. Despite the negative impact of stigma on HIV outcomes, culturally and contextually sensitive interventions to mitigate the negative effects of internalized stigma associated with HIV among women living with HIV (WLWH) are limited and critically needed in Tanzania. In Tanzania, where 80% of the population lives in rural areas and HIV is the third leading cause of death, an estimated 810,000 women are living with HIV. 4.5% of Tanzanian adults between the ages of 15 and 49 were living with HIV with the prevalence being higher among women (? = 5.5%:?=3.4%). Additionally, the prevalence of HIV is highest among women aged 45-49, at 12% (compared with 8.4% among men of this age). Further, there are disproportionate rates of new infections among young women in Tanzania (ages 15-24) compared to their male counterparts of the same age. The 2016-2017 Tanzania Impact Survey identified that women between the ages of 15 and 39 are more than twice as likely to be living with HIV as their male counterparts. Thus, in recruiting WLWH for this study, we will purposively recruit based on geography (urban and rural) and ensure that WLWH across the age spectrum are sufficiently represented. Labda Siku Moja: Sauti za Wanawake Wanaoishi na VVU (Maybe Someday: Voices of Women Living with HIV), was identified as a culturally acceptable internalized stigma reduction intervention among Tanzanian WLWH. In Tanzania, where storytelling is an important part of the oral literature and culture, the stories of the Labda Siku Moja can help individuals acknowledge and reflect upon new truths in relation to self and their world producing transformations and insights that endure. Thus, the specific aims for this proposed study are to: Aim 1: Assess the feasibility (recruitment and retention metrics; time to administer and completeness of study instruments; fidelity to intervention; evaluation of study processes) of implementing an internalized stigma reduction intervention among urban and rural Tanzanian WLWH; and Aim 2: Test preliminary efficacy and determine effect sizes of an internalized stigma reduction intervention among urban and rural WLWH (N = 160) using a 2x4 repeated measures randomized controlled trial (2 treatments x 4 time points [baseline, 30 days, 90 days, 180 days]) to determine if the Labda Siku Moja intervention results in reduced stigma and improved self-esteem and coping self-efficacy (proximal targets).

IC Name
FOGARTY INTERNATIONAL CENTER
  • Activity
    R21
  • Administering IC
    TW
  • Application Type
    1
  • Direct Cost Amount
    146000
  • Indirect Cost Amount
    59780
  • Total Cost
    205780
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    989
  • Ed Inst. Type
  • Funding ICs
    FIC:205780\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    DUKE UNIVERSITY
  • Organization Department
  • Organization DUNS
    044387793
  • Organization City
    DURHAM
  • Organization State
    NC
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    277054673
  • Organization District
    UNITED STATES