It is an object of the present invention to provide an ejection liquid (liquid composition) which can be stably ejected as a liquid containing an effective ingredient for treating respiratory disease from an ejection opening provided to an ejection device. A specific surface-active compound is added to an ejection liquid containing an effective ingredient for treating respiratory disease. An ejection liquid which is used for stably ejecting a solution containing an active ingredient for treating respiratory disease according to the principle of an ink jet system, a method which is suitable for ejecting this ejection liquid, and an ejection device are provided. The ejection liquid includes an active ingredient for treating j respiratory disease, a specific surface-active compound, and a liquid medium and is ejected from an ejection opening by an ink jet system.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
FIG. 1 is an explanatory schematic view of an inhaler head cartridge unit.
FIG. 2 is a perspective view of an inhaler.
FIG. 3 is a perspective view of the inhaler of FIG. 2 in a state that an access cover is opened.
Claims
1. An ejection liquid being ejected from an ejection opening by an ink jet system and being used for treating respiratory disease, the ejection liquid comprising:
an active ingredient for treating respiratory disease;a surface-active compound represented by the following Formula (1):
R−A   (1)wherein R denotes a substituted or unsubstituted, saturated or unsaturated aliphatic chain of 3 or more and 30 or less carbon atoms or a saturated or unsaturated aliphatic derivative of 3 or more and 30 or less carbon atoms, andA comprises at least one selected from the group consisting of a substituted or unsubstituted carboxylic acid group, a substituted or unsubstituted sulfonic acid group, a substituted or unsubstituted anion and its counter ion, a substituted or unsubstituted quaternary ammonium group, a substituted or unsubstituted cation and its counter ion, and a betaine skeleton,or an amine oxide or water-soluble nonionic compound having a substituted or unsubstituted, saturated or unsaturated aliphatic chain of 3 or more and 30 or less carbon atoms; anda liquid medium.
2. The ejection liquid according to claim 1, wherein the surface-active compound represented by Formula (1) comprises a substituted or unsubstituted alkyl group of 3 or more and 30 or less carbon atoms and is at least one selected from the group consisting of:
alkyl amino acid,alkyl betaine,fatty acyl betaint,fatty acyl alkyl betaine,alkyl imidazolinium betaine,fatty acyl amino acid,alkyl sulfonic acid,alkylbenzene sulfonic acid,alkylether amino acid salt,acylamino acid pyrroridone carboxylate,alkylamine oxide,fatty acyl amine oxide,fatty amino acid salt,ethylene diamine derivative,pyrroridone carboxylic acid,benzalkonium salt,benzethonium salt, andfatty acyl polyoxyethylene sorbitan alkylate.
3. The ejection liquid according to claim 1, wherein the active ingredient for treating respiratory disease is at least one selected from the group consisting of cromoglycate, salbutamol, ipratropium, fenoterol, isoproterenol, trimetoquinol, procaterol, salmeterol, oxitropium, beclomethasone propionate, bromhexine, acetylcysteine, budesonide, fluticasone propionate, derivatives of these compounds, salts of these compounds and their derivatives, and a mixture of at least two of these compounds and their derivatives.
4. The ejection liquid according to claim 1, wherein the ejection liquid is ejected from an ejection opening of an ejection device by thermal energy.
5. A method for ejecting a liquid, wherein an ejection liquid according to claim 1 is ejected by an ink jet system from a device ejecting a drug for treating respiratory disease.
6. The method for ejecting a liquid according to claim 5, wherein the ink jet system is a thermal ink jet system using thermal energy.
7. A liquid ejection cartridge, the cartridge comprising a tank for storing an ejection liquid according to claim 1 and an ejection head.
8. The liquid ejection cartridge according to claim 7, wherein the ejection head ejects a liquid by a thermal ink jet system.
9. An ejection device for treating respiratory disease, the ejection device comprising the cartridge according to claim 7; and a channel and an opening for leading a liquid to be ejected from a liquid-ejecting portion of a head of the cartridge to an inhalation region of a user.
10. The ejection device according to claim 9, the device being used for inhalation through a mouth of a user.
Patent Application
20070221215
