ELECTRONIC ATLAS OF FETAL BRAIN GENE EXPRESSION

Information

  • Research Project
  • 6894205
  • ApplicationId
    6894205
  • Core Project Number
    R01HD039928
  • Full Project Number
    3R01HD039928-03S1
  • Serial Number
    39928
  • FOA Number
    PAR-99-138
  • Sub Project Id
  • Project Start Date
    8/18/2000 - 24 years ago
  • Project End Date
    6/30/2005 - 19 years ago
  • Program Officer Name
    HENKEN, DEBORAH B.
  • Budget Start Date
    7/1/2002 - 22 years ago
  • Budget End Date
    6/30/2005 - 19 years ago
  • Fiscal Year
    2004
  • Support Year
    3
  • Suffix
    S1
  • Award Notice Date
    9/28/2004 - 20 years ago
Organizations

ELECTRONIC ATLAS OF FETAL BRAIN GENE EXPRESSION

The general aim is to gain insight into embryonic human brain development, partly because of the need to provide a framework for understanding abnormalities of brain development which occur during the embryonic period and which are common and can be severe. The broad, long-term objectives are two-fold: (1) to acquire high resolution gene expression data for embryonic human brain that will permit comparison with equivalent data being generated for animal models, notably the mouse. This will provide molecular anatomical landmarks of embryonic human brain development to supplement existing standard anatomical landmarks. In addition it will permit an assessment of species differences (and similarities) in embryonic gene expression patterns, and provide a measure of just how far we can confidently extrapolate from animal models. (2) to establish an interactive graphical database of high resolution human embryonic brain gene expression patterns mapped onto an anatomical framework. This will involve: (i) 3-D reconstruction of electronically digitised 2-D expression images and of histological images in test samples, and referencing against 3-D reconstruction of anatomy in histological reference embryos, (ii) database design and operability issues.

IC Name
EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH &HUMAN DEVELOPMENT
  • Activity
    R01
  • Administering IC
    HD
  • Application Type
    3
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    39284
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    865
  • Ed Inst. Type
  • Funding ICs
    NICHD:12500\NIMH:26784\
  • Funding Mechanism
  • Study Section
    ZMH1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    UNIVERSITY OF NEWCASTLE
  • Organization Department
  • Organization DUNS
    211193750
  • Organization City
    NEWCASTLE UPON TYNE
  • Organization State
  • Organization Country
    UNITED KINGDOM
  • Organization Zip Code
    NE1 7RU
  • Organization District
    UNITED KINGDOM