Claims
- 1. An embolic composition, comprising:
a first collection of particles having a first shape; and a second collection of particles having a second shape different than the first shape.
- 2. The composition of claim 1, wherein the first shape is substantially free of a concave region.
- 3. The composition of claim 2, wherein the first shape is substantially spherical.
- 4. The composition of claim 1, wherein the second shape is flake-like.
- 5. The composition of claim 1, wherein the second shape is strand-like.
- 6. The composition of claim 1, wherein the second shape includes a generally convex region.
- 7. The composition of claim 1, wherein the second shape comprises a fibrous element extending from a base.
- 8. The composition of claim 1, wherein the particles in the first collection and the particles in the second collection have different compositions.
- 9. The composition of claim 1, wherein the particles of at least one of the collections comprise a therapeutic agent.
- 10. The composition of claim 9, wherein the particles of only one collection comprise the therapeutic agent.
- 11. The composition of claim 9, wherein the particles in the first collection comprise a first therapeutic agent, and the particles in the second collection comprise a second therapeutic agent different than the first therapeutic agent.
- 12. The composition of claim 9, wherein the first collection comprises more particles than the second collection.
- 13. The composition of claim 1, wherein the particles of at least one of the collections define a cavity, and comprise a therapeutic agent in the cavity.
- 14. The composition of claim 1, wherein the particles of at least one of the collections comprise a radiopaque material.
- 15. The composition of claim 1, wherein the particles of at least one of the collections comprise a portion capable of dissolving in a body.
- 16. The composition of claim 1, wherein the particles of at least one of the collections comprises a shape memory material and a non-shape memory material.
- 17. The composition of claim 1, wherein the particles of the first collection is spherical, and the particles of the second collection are non-spherical.
- 18. The composition of claim 1, wherein the particles of the first and second collections have different hardness.
- 19. The composition of claim 1, wherein the particles of at least one of the collections comprise a material capable of increasing in volume upon exposure to a predetermined stimulus.
- 20. The composition of claim 19, wherein the material comprises a hydrogel.
- 21. The composition of claim 1, wherein the particles in the first collection and the particles in the second collection have different sizes.
- 22. The composition of claim 21, wherein the size of the particles of at least one of the collections is about 1,200 microns or less.
- 23. The composition of claim 1, wherein the first and second collections are configured to engage with each other.
- 24. The composition of claim 1, wherein the first collection comprises particles comprising a shape memory material.
- 25. An embolic composition, comprising:
a first collection of particles having a first composition; and a second collection of particles having a second composition different from the first composition.
- 26. The composition of claim 25, wherein at least one collection of particles comprises a shape memory material.
- 27. The composition of claim 25, wherein the particles in the first collection include a generally concave region.
- 28. The composition of claim 27, wherein the particles in the second collection is substantially free of concave regions.
- 29. A composition, comprising:
a first embolic agent of a first phase; and a second embolic agent of a second phase different than the first phase.
- 30. The composition of claim 29, wherein the first embolic agent comprises solid embolic particles.
- 31. The composition of claim 29, wherein the first embolic agent comprises a liquid, a gel, or a foam.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation-in-part application of and claims priority to U.S. application Ser. No. 10/278,248, entitled “Mixing and Delivery of Therapeutic Compositions” and filed on Oct. 23, 2002, hereby incorporated by reference in its entirety. Also, this application is related to U.S. application Ser. No. ______ [Attorney Docket No. 01194-823001], filed on the same day as this application.
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
10278248 |
Oct 2002 |
US |
Child |
10700970 |
Nov 2003 |
US |