Claims
- 1. Column endpiece, for a chromatography column, through which eluent flows, comprising a base part, an extension piece for a discharge tube and a frit, the base part having an essentially funnel-shaped contour, characterized in that, when the eluent is flowing through, the said frit produces a pressure drop per unit length that is at least twice as great as the pressure drop per unit length which is created in the sorbent packing when the eluent is flowing through.
- 2. Column endpiece according to claim 1, characterized in that the contour is concavely curved.
- 3. Column endpiece according to claim 1, characterized in that the contour is convexly curved.
- 4. Column endpiece according to claim 1, characterized in that the contour is curved, and in that the curvature has a concave and a convex part.
- 5. A chromatographic method comprising flowing an eluent through a chromatography column employing the endpiece of claim 1, such that when the eluent is flowing through, The said frit produces a pressure drop per unit length that is at least twice as great as the pressure drop per unit length which is created in the sorbent packing when the eluent is flowing through.
- 6. Column endpiece according to claim 1, wherein in any cross-section of the base part all liquid particles have the same axial velocity component.
- 7. Column endpiece according to claim 1, wherein the contour is parabolic.
- 8. Column endpiece according to claim 1, wherein the contour is exponential.
- 9. Column endpiece according to claim 1, wherein the contour is sigmoidal.
- 10. Column endpiece according to claim 1, wherein the contour is conical.
- 11. A separating column comprising:a body; and the column endpiece according to claim 1, wherein the endpiece is screwably connected to the body.
- 12. A separating column comprising:the column endpiece according to claim 1, wherein the endpiece is formed integrally with the column.
- 13. Column endpiece according to claim 1, wherein the base part contains fitments.
- 14. Column endpiece according to claim 1, wherein the base part contains a porous material.
- 15. Column endpiece according to claim 14, wherein the porous material is sintered or adhesively bonded.
- 16. Column endpiece according to claim 14, wherein the porous material comprises loose particles.
- 17. Column endpiece according to claim 1, wherein the base part contains sorbent material supported by a frit located in the outlet tube.
Priority Claims (1)
Number |
Date |
Country |
Kind |
197 10 117 |
Mar 1997 |
DE |
|
REFERENCE TO RELATED APPLICATIONS
This application is a 371 of PCT/EP98/01052 filed Feb. 25, 1998.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
102e Date |
371c Date |
PCT/EP98/01052 |
|
WO |
00 |
9/13/1999 |
9/13/1999 |
Publishing Document |
Publishing Date |
Country |
Kind |
WO98/40734 |
9/17/1998 |
WO |
A |
US Referenced Citations (4)
Foreign Referenced Citations (1)
Number |
Date |
Country |
9514220 |
May 1995 |
WO |