Claims
- 1. A compound of the formula (I)
- 2. The compound according to claim 1, which is the compound of formula (II)
- 3. The compound according to claim 1, which is the compound of formula (III)
- 4. The compound according to claim 1, which is the compound of formula (IV)
- 5. A process for the preparation of the compound of formula (I), according to claim 1 comprising:
1. extracting the plant Beilschmiedia fulva, PLA 101037, or cell cultures of the plant Beilschmiedia fulva, PLA 101037, under suitable conditions, 2. isolating the compound of the formula (IV), 133. where appropriate derivatizing to a compound of the formula (I) and/or reacting to give a physiologically tolerated salt of the compound of the formula (I).
- 6. A process for the preparation of the compound of formula (IV) according to claim 4 comprising:
1. extracting the plant Beilschmiedia fulva, PLA 101037, or cell cultures of the plant Beilschmiedia fulva, PLA 101037, under suitable conditions, 2. isolating the compound of the formula (IV), and 3. where appropriate reacting to give a physiologically tolerated salt of the compound of the formula (IV).
- 7. A pharmaceutical composition comprising a compound of claim 1 or a pharmacologically tolerable salt thereof and one or more physiologically acceptable excipients.
- 8. A process for the preparation of a pharmaceutical composition as claimed in claim 7, comprising bringing a compound of formula (I), or a pharmacologically tolerable salt thereof, into a suitable administration form using one or more physiologically suitable excipients.
- 9. A method of inhibiting c-maf and NFAT to treat a disease or disorder which comprises administering to a patient in need of said treatment or disorder an effective c-maf and NFAT inhibitory amount of a compound according to claim 1.
- 10. The method according to claim 9 wherein the disease or disorder is selected from the group consisting of allergies, asthma and inflammatory symptoms associated with asthma.
Priority Claims (1)
Number |
Date |
Country |
Kind |
10235624.6 |
Aug 2002 |
DE |
|
Parent Case Info
[0001] This application claims the benefit of U.S. Provisional Application No. 60/438,283 filed Jan. 6, 2003, and right of priority from German Patent Application No. 10235624.6, filed Aug. 2, 2002.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60438283 |
Jan 2003 |
US |