Shair, et al J. Org. Chem. vol. 59 pp. 3755-3757 (1994). |
Yoon et al. J. Org. Chem. vol. 59 pp. 3752-3755 (1994). |
Chem & Eng News Jan. 23 1995 p. 22 (1995). |
Myers et al J. Am. Chem. Soc. vol. 116 pp. 11556-11557 (1994). |
Myers et al Chem. Abstr. vol. 121 Entry 280446 (1995). |
Registry No. 158818-85-0 (1994). |
T. Yoon, Ph.D. Dissertation, Yale University, 1994, 23-31, 57-63; U.S.A. |
L.M. Hinman and G. Yarranton, "New Approaches to Non-Immunogenic Monoclonal Antibody Cancer Therapies," Ann. Repts. Med. Chem., 1993, 237-246; U.S.A. |
M. Konishi, H. Ohkuma, K. Matsumoto, T. Tsuno, H. Kamei, T. Miyaki, T. Oki, H. Kawaguchi, G.D. VanDuyne, and J. Clardy, "Dynemycin A, A Novel Antibiotic with the Anthraquinone and 1,5-Diyn-3-ene Subunit," J. Antibiot., 1989, 42(9), 1449-1452; Japan. |
A.G. Myers, M.E. Fraley and N.J. Tom, "Highly Convergent Route to Dynemicins of Wide Structural Variability. Enantioselective Synthesis of Quinone Imine Precursors to Natural and Nonnatural Dynemicins," J. Amer. Chem. Soc., 1994, 116, 11556-7; U.S.A. |
K. C. Nicolaou and W.-M. Dai, "Chemistry and Biology of the Enediyne Anticancer Antibiotics," Angew. Chem. Int. Ed. Engl., 1991, 30, 1387-1416; Germany. |
K.C. Nicolaou, W.-M. Dai, S.-C. Tsay, V.A. Estevez, W. Wrasidlo, "Designed Enediynes: A New Class of DNA-Cleaving Molecules with Potent and Selective Anticancer Activity," Science (Washington, D.C.), 1992, 256, 1172-1178; U.S.A. |
M.F. Semmelhack, J.J. Gallagher, W.-d. Ding, G. Krishnamurthy, R. Babine, and G.A. Elstead, "The Effect on DNA CLeavage Potency of Tethering a Simple Cyclic Enediyne to a Netropsin Analog," J. Org. Chem., 1994, 59, 4357-4359; U.S.A. |
M.D. Shair, T. Yoon, T.-C. Chou and S.J. Danishefsky, "Enediyne Quinone Imines: Truncated Biologically Active Dynemicin Congeners," Angew. Chem. Int. Ed. Engl., 1994, 33, 2477-2479; Germany. |
M.D. Shair, T. Yoon and S.J. Danishefsky, "A Remarkable Cross Coupling Reaction to Construct the Enediyne Linkage Relevant to Dynemicin A: Synthesis of the Deprotected ABC System," J. Org. Chem., 1994, 59, 3755-3757; U.S.A. |
P.A. Trail, D. Willner, S.J. Lasch, A.J. Henderson, S. Hofstead, A.M. Casazza, R.A. Firestone, I. Hellstrom, and K.E. Hellstrom, "Cure of Xenografted Human Carcinomas by BR96-Doxorubicin Immunoconjugates," Science (Washington, D.C.), 1993, 261, 212-215; U.S.A. |
P.A. Wender, C.K. Zercher, S. Beckham, and E.-M. Haubold, "A Photochemically Triggered DNA Cleaving Agent: Synthesis, Mechanistic and DNA Cleavage Studies on a New Analog of the Antitumor Antibiotic Dynemicin," J. Org. Chem., 1993, 58(22), 5867-5869; U.S.A. |
T. Yoon, M.D. Shair, S.J. Danishefsky, and G.K. Shulte, "Experiments Directed toward a Total Synthesis of Dynemicin A: A solution to the Stereochemical Problem," J. Org. Chem., 1994, 59, 3752-3754; U.S.A. |