Claims
- 1. A method for enhancing learning and memory or treating amnesia, comprising administrating to a subject in need thereof an effective amount of a compound of the formula:
- 2. The method of claim 1, wherein A is
- 3. The method of claim 2, wherein Ar1 is phenyl.
- 4. The method of claim 3, wherein R1 and R2 are substituted at positions 4 and 5 of phenyl, respectively.
- 5. The method of claim 2, wherein Ar2 is 5′-furyl.
- 6. The method of claim 5, wherein one of R3 and R4 is substituted at position 2 of furyl.
- 7. The method of claim 2, wherein Ar3 is phenyl.
- 8. The method of claim 7, wherein n is 1.
- 9. The method of claim 8, wherein Ar1 is phenyl.
- 10. The method of claim 9, wherein R1 and R2 are substituted at positions 4 and 5 of phenyl, respectively.
- 11. The method of claim 10, wherein Ar2 is 5′-furyl.
- 12. The method of claim 11, wherein each of R5 and R6 is H, and one of R3 and R4 is substituted at position 2 of furyl.
- 13. The method of claim 12, wherein each of R1 and R2 is H.
- 14. The method of claim 13, wherein one of R3 and R4 is H, and the other is CH2NCH3.
- 15. The method of claim 13, wherein one of R3 and R4 is H, and the other is CH2OH.
- 16. The method of claim 13, wherein one of R3 and R4 is H, and the other is CH2OCH3.
- 17. The method of claim 13, wherein one of R3 and R4 is H, and the other is COOCH3.
- 18. The method of claim 12, wherein one of R3 and R4 is H, and the other is CH2OH.
- 19. The method of claim 18, wherein each of R1 and R2 is H.
- 20. The method of claim 18, wherein R1 is H, and R2 is F.
- 21. The method of claim 18, wherein R1 is H, and R2 is OCH3.
- 22. The method of claim 18, wherein R1 and R2 together are OCH2O.
- 23. The method of claim 2, wherein Ar1 is thienyl.
- 24. The method of claim 3, wherein Ar2 is phenyl.
- 25. The method of claim 24, wherein one of R3 and R4 is substituted at position 4 of phenyl.
- 26. The method of claim 25, wherein one of R3 and R4 is H, and the other is CH3.
- 27. The method of claim 24, wherein Ar3 is phenyl.
- 28. The method of claim 27, wherein n is 1.
- 29. The method of claim 28, wherein one of R3 and R4 is substituted at position 4 of phenyl.
- 30. The method of claim 29, wherein one of R3 and R4 is H, and the other is CH3.
- 31. The method of claim 30, wherein each of R1 and R2 is H, one of R5 and R6 is H, and the other is Cl substituted at position 3 of phenyl.
- 32. The method of claim 30, wherein each of R1 and R2 is H, one of R5 and R6 is H, and the other is NO2 substituted at position 4 of phenyl.
- 33. The method of claim 1, wherein A is H.
- 34. The method of claim 33, wherein Ar1 is phenyl.
- 35. The method of claim 34, wherein R1 and R2 are substituted at positions 4 and 5 of phenyl, respectively.
- 36. The method of claim 35, wherein Ar2 is 5′-furyl.
- 37. The method of claim 36, wherein one of R3 and R4 is substituted at position 2 of furyl.
- 38. The method of claim 37, wherein each of R1 and R2 is H.
- 39. The method of claim 38, wherein one of R3 and R4 is H, and the other is COOCH3.
- 40. The method of claim 33, wherein Ar2 is 5′-furyl.
- 41. The method of claim 40, wherein one of R3 and R4 is substituted at position 2 of furyl.
RELATED APPLICATIONS
[0001] This application claims priority to U.S. provisional application No. 60/322,389 filed on Sep. 14, 2001.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60322389 |
Sep 2001 |
US |