Claims
- 1. A purified MAP2 protein kinase comprising an amino acid sequence as set forth in SEQ ID NO:2.
- 2. The purified MAP2 protein kinase of claim 1, having an amino acid sequence as set forth in SEQ. I.D. No. 2.
- 3. A purified MAP2 protein kinase designated ERK1 encoded by a nucleic acid molecule selected from the group consisting of:(a) a nucleic acid molecule comprising a nucleotide sequence as set forth in SEQ ID NO:1; and (b) a nucleic acid molecule comprising a nucleotide sequence that, as a result of the degeneracy of the genetic code, differs from the nucleotide sequence of (a) and encodes the MAP2 protein kinase designated ERK1 as set forth in SEQ ID NO:2.
- 4. A purified MAP2 protein kinase designated ERK1 encoded by the plasmid designated pBS-rERK1 (ATCC® Accession No. 40808).
Parent Case Info
This is a file wrapper continuation of application U.S. Ser. No. 08,462,874, filed Jun. 5, 1995, now abandoned, which is a divisional of U.S. Ser. No. 08/178,488, filed Jan. 7, 1994, now abandoned, which is a continuation of U.S. Ser. No. 07/701,544, filed May 16, 1991, now abandoned, which is a continuation-in-part of U.S. Ser. No. 07/532,004, filed Jun. 1, 1990, now abandoned, each of which is incorporated by reference herein in its entirety.
Government Interests
Pursuant to the provisions of 35 U.S.C. §202(c), it is hereby acknowledged that the Government has certain rights in this invention, which was made in part with fund; from the National Institutes of Health.
Non-Patent Literature Citations (7)
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Hoshi, M. et al. J. Biol. Chem. 263: 5396-5401, Apr. 1988.* |
Miyasaka, T. et al. J. Biol. Chem. 265: 4730-4735, Mar. 1990.* |
Hanks, S. K. et al. Science 241: 42-52, Jul. 1988.* |
Rudinger, J., Peptide Hormones, Parsons (Ed.), University Park Press, Baltimore, MD. pp. 1-7, Jun. 1976.* |
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Continuations (2)
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08/462874 |
Jun 1995 |
US |
Child |
08/932012 |
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US |
Parent |
07/701544 |
May 1991 |
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Child |
08/178488 |
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US |
Continuation in Parts (1)
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07/532004 |
Jun 1990 |
US |
Child |
07/701544 |
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US |