Claims
- 1. An ester of acyl L-carnitine of the general formula ##STR6## wherein: R is a straight or branched saturated aliphatic hydrocarbon carboxylic acyl group having 2-16 carbon atoms,
- n is an integer from 7 to 15, and
- X.sup.- is the anion of a pharmacologically acceptable acid.
- 2. An ester of claim 1 wherein R is isobutyryl or isovaleryl.
- 3. An ester of claim 1 wherein n is 10.
- 4. An ester of claim 1 wherein X.sup.- is selected from: chloride; bromide; iodide; acid aspartate; acid citrate; tartrate; acid phosphate; acid fumarate; glycerophosphate; glucosephosphate; lactate; acid maleate; orotate; acid oxalate; acid sulphate; trichloroacetate, trifluoroacetate and methansulphonate.
- 5. Isovaleryl L-carnitine undecyl ester chloride.
- 6. Isobutyryl L-carnitine undecyl ester chloride.
- 7. An orally or parenterally administrable antibacterial pharmaceutical composition comprising an ester of claims 1, 4, 5, or 6 as active ingredient in antibacterially effective amount and a pharmacologically acceptable excipient.
- 8. The antibacterial pharmaceutical composition of claim 7 for treating diseases the aetiologic agent whereof is a bacterium of the genus Campylobacter and the active ingredient is present in amount antibacterially effective against said bacterium.
- 9. The pharmaceutical composition of claim 7 for treating an infection sustained by Gram negative or Gram positive bacteria wherein the active ingredient is present in an antibacterially effective amount against said bacteria.
- 10. An ester of claim 4, wherein R is isobutyryl or isovaleryl.
- 11. An ester of claim 4, wherein n is 10.
- 12. The antibacterial pharmaceutical composition of claim 7 for treating diseases the aetiologic agent whereof is a bacterium of the genus Helicobacter and the active ingredient is present in amount antibacterially effective against said bacterium.
Priority Claims (1)
Number |
Date |
Country |
Kind |
RM92A0027 |
Jan 1992 |
ITX |
|
Parent Case Info
This application is a Continuation of application Ser. No. 08/000,710, filed on Jan. 5, 1993, now abandoned.
US Referenced Citations (6)
Foreign Referenced Citations (1)
Number |
Date |
Country |
2096136 |
Oct 1982 |
GBX |
Continuations (1)
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Number |
Date |
Country |
Parent |
710 |
Jan 1993 |
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