The disclosure relates to the field of dispensing liquid eye drops. Particular embodiments relate to an applicator that can separate a portion of liquid from reservoir in a manner that retains the integrity of the remaining liquid. Further the disclosed embodiments will allow user to dispense and transfer a droplet or quantity of liquid in a controlled fashion using but not limited to the properties of liquid cohesion, adhesion and surface tension to the structural components of the device. Further the disclosed embodiments will temporarily suspend the desired droplet or quantity of liquid on the terminal end of the device in a manner to facilitate easy safe transfer to the eye surface.
Instillation of eye drops from a bottle onto the surface of the eye has always been difficult at best. The current convention is to hold an eye dropper above the eye and in some fashion make a droplet break off of the container and fall by gravity onto the surface of the eye or inside the eyelid. This conventional method presents many hazards including, apparatus impacting the eye surface, reservoir and dispensing tip contamination, medication misplacement outside of the eye, waste by applying multiple drops among other problems. Technical limitations of the user exacerbate an already cumbersome process. Those with visual impairment, tremor, impaired dexterity, and the elderly or otherwise limited sometimes forgo needed eye drops because of the difficulty of the process.
Even aided by a mirror liquid instillation is somewhat of a blind endeavor adding to existing hazards. The closer to the eye the dropper is held to the eye the better chance of getting the liquid in the appropriate location, but this fact presents a hazard to critical eye structures. Many medical studies have verified that the tip of the eye dropper often comes into contact with structures such as the eyelid, eye surface or face where it can be contaminated with bacteria. This becomes problematic when bacteria now present on the tip of the device are transferred to the reservoir through the existing open conduit. This happens when the force which initially pushes out the droplet is withdrawn and the resulting negative pressure in the reservoir and liquid is aspirated up from the tip into the reservoir. These facts present juxtaposition for the user, making it necessary to choose either to hold the dropper closer to minimize misplacement and risk contact with the eye and/or contamination of the contents, or to hold it further away and risk missing the eye. Having objects in very close proximity to the eye presents an obvious injury hazard especially if these objects are rigid or otherwise less conformal than the surface of the eye.
Devices exist that can temporarily hold a droplet on a separate apparatus from the eye dropper and facilitate transfer to the eye surface. This too can be cumbersome because it takes coordination and fine dexterity to “load” the droplet on this apparatus and then transfer it to the eye surface. Some frustrated users have also saturated Q-tips with eye medication in an attempt to transfer the liquid with less mess.
Current eye droppers function according to “the bombing method” where an eye drop falls from above the eye, accelerates by gravity, and contacts the corneal or other eye surface transferring force to it. Hitting the corneal surface is problematic because it's very sensitive and can stimulate a squinting reflex. When triggered by falling eye drops this reflex decreases the holding space on the surface of the eye and forces the eye drops that were newly instilled off of the eye surface before the purpose of administration is achieved. This is often evidenced as “tearing” that occurs after an eye drop is instilled. Most of the liquid running out of the eye after instillation is the liquid that has just been instilled. Eye drops running down the face have obvious cosmetic, financial and medical implications. Many aids and devices exist to help “aim” the eye drops yet again prove that instillation of eye drops is difficult at best even while attempting administration under limited visualization. The components of this apparatus will allow the user to bypass a gravity propelled system eye drop delivery and retain control of the liquid until delivery at the eye.
While the presently disclosed inventive concepts are susceptible of various modifications and alternative constructions, certain illustrated embodiments thereof have been shown in the drawings and will be described below in detail. It should be understood, however, that there is no intention to limit the inventive concepts to the specific form disclosed, but, on the contrary, the presently disclosed and claimed inventive concepts is to cover all the modifications, alternative constructions, and equivalents falling within the spirit and scope of the inventive concepts as defined there in.
Embodiments of the disclosed dropper device use an elastomeric material as its base component such as silicone, rubber or latex (but not limited to these materials) which will allow it to stretch and “form fit” over existing eye dropper bottles in a universal fashion. This allows the dropper device to readily adapt to different size containers and geometry of dispensers. The elasticity of these materials will also be utilized to form a seal between the device and the existing eye dropper bottle dispensing apparatus or reservoir. Elasticity of the elastomer could be changed as desired to increase the functionality of the product. For instance, Shore 25A could be utilized but if more elasticity was desired Shore 20A could be used. An alternate embodiment of attachment is an elastomeric tip that will fit in the neck of the reservoir opening replacing the original tip. The elastomeric properties will again allow the male end of the elastomeric tip to seal to the reservoir opening and remain in place to perform its function, similar to a cork in a bottle. In summary the elastomer can be utilized to adapt over and into an existing reservoir as required but the function of the device will be unaltered. In some circumstances the reservoir may be continuous with the device, for example when the device is configured to be compatible with single use eye droppers constructed of silicone. Some of these elastomers may have intrinsic antimicrobial properties.
Further, the elastomeric material preferably is configured with liquid repellent properties, such as hydrophobicity and oleophobicity, which repel excess residue from the internal and external structures when application and usage is taking place. The elastomeric surface can be configured as needed with a micro or nanosurface to alter the liquid surface interface and thereby augment function.
After the dropper device is secured over the existing dropper bottle or reservoir an effective seal is obtained sufficient that gentle force can be applied to the sidewalls of the reservoir to push fluid down a flexible elastomeric conduit.
The flexible elastomeric conduit provides a conduit to convey the liquid away from the reservoir toward the end of dispensing termini of the apparatus. In a preferred embodiment, the liquid will then enter a conveyance space (collapsed tube) that is fully closed at rest by elastomeric recoil. A conceptual illustration of this concept is a cut made though a tube that has been filled with silicone. In the resting or native state the silicone is collapsed and the cut may not be visible yet when liquid is pressurized at one end it opens allowing liquid to flow through and immediately collapses and seals shut in the absence of pressure. The collapsed tube is of varying length and will serve the user in allowing control while dispensing by placing a slight resistance to the flow of liquid out of the reservoir. As pressure is applied at the reservoir the liquid will leak through this collapsed tube and form a drop. The collapsed tube allows the drop to form slowly providing the user control of the speed with which the liquid comes out of the tip and forms the drop. Having a controlled formation of the drop provides an important difference from the operation of a typical eye dropper bottles which allow the liquid to jet out with little force. This cut or slit will reseal (collapse) the tube so no flow take place when the reservoir is depressurized. This resealing or collapsing is is caused by providing the slit being formed in resiliently collapsible body, allowing it to reseal and this feature will serve to reduce or eliminate reflux into the reservoir.
When pressure is applied at the reservoir this formerly collapsed conduit will be forced open and liquid will flow through it. After the reservoir is relieved of pressure the elastomer will recoil and the collapsed tube will shut. Liquids may have as high viscosity such as paste can also be transmitted through this system. Once the quantity of liquid formed at the end of the conveyance system is large enough it will start to move, propelled by gravity. The length of the conveyance structure consisting of a dynamic passageway operated by elastomeric recoil will highly influence the overall length of the device and can be adapted according to use needs. The geometric properties including but not limited to the length of the conduit can be adjusted to allow liquid dispensing at variable speed and variable force input required at the reservoir. A short tube may be needed to make a more compact device that travels well for instance.
Liquid is forced into the conveyance system by compressing and increasing the pressure in the bottle or reservoir as is standard practice. Once an eye drop is dispensed and the force of compression is released then suction is generated at the reservoir. This suction at the reservoir will cause the collapsed elastomeric passageway to adhere with more force preventing any substance beyond the conveyance system terminal from going back into the reservoir. Factors which will reduce contamination include, but not limited to, a relatively narrow collapsed conveyance system, elastomeric recoil of the conveyance system which is collapsed at a resting state and the negative pressure at the reservoir created by the void from dispensed liquid.
In a preferred embodiment one or more structures near the end of the tube will contact the droplet as it forms or shortly after it has finished forming or after it falls or otherwise moves aided by gravity. The liquid falls a very short distance aided by gravity similar to a standard eye dropper bottle. The liquid will encounter and adhere to these structures after it begins to fall and effectively “guide it” to the desired location. Surface tension properties of the liquid along with adhesion of the liquid to the elastomer will facilitate transfer to the suspension frame. Liquid will cling to the structures at the dispensing end (or tip) of the apparatus both while moving and while at rest utilizing adhesion principles. Adhesion is when liquid droplets cling to solid structures such as early morning dew on plants. Cohesion causes the liquid droplet to remain together with the configuration of the device be such that this property is employed to allow the device to function. This is known colloquially as surface tension.
This device is configured in multiple parameters not limited to geometry, surface composition and microstructure to accomplish this purpose. Furthermore the configuration of the components can be manipulated to change the functionality of the device by directly harnessing the physics of liquid properties. For instance the geometry and surface properties of the tip could be changed to enhance the liquid “bead up” and allow user visualization and transfer from the device tip to the eye. There are innumerable configurations that can be employed to slightly alter the function of the device but the basic principle is that the device is configured to utilize these forces to hold the liquid quantity and then facilitate easy and safe transfer the ocular surface. Once the droplet reaches the terminal geometric configuration of the device it will be temporarily suspended for application.
The configuration at the end of the collapsed conveyance system can be manipulated to dispense the desired volume of the droplet or liquid. This will largely be determined by the nipple or the nozzle at the end of the conveyance system that is closed under a resting state. Nozzles with a finer tip will produce a smaller droplet and larger more blunt ones will produce a larger volume droplet. This will be similar to what one would find under the cap of an off the shelf eye dropper only in this device it is placed on the end of the improved conveyance system. Moreover, the liquid volume formation apparatus will have geometric configuration to keep the volume of liquid together until it reaches critical mass to move.
A preferred embodiment of this device is that it will break off a preconfigured volume of liquid and separate it from the liquid in the reservoir and transfer it to a portion of the liquid to a location on the end of the device that will hold it for application on the surface of the eye. This device contains embodiments that allow for controlled liquid dispensing and subsequent transmission of the liquid to suspension frame where the liquid is contained by harnessing the cohesion and adhesion properties of a liquid volume or droplet. The liquid or droplet will then be brought in very close approximation to the moisturized surface of the eye, and it will spontaneously transfer to the eye. The unique geometry of this device makes temporary suspension of the droplet possible.
Gravity will preferably provide some or all of the force for movement of the liquid droplet between the nozzle (also known as the terminal of the conveyance structures) and the holding apparatus on the end. The configuration of the structures between the terminal of the conveyance system and the suspension frame are designed to facilitate optimal transfer. This will keep drops from prematurely falling away from the entire apparatus. The connecting structures may vary in distance from each other in size, shape, length, surface area, material composition and geometric configuration but are not limited to these mentioned variances. A conceptual illustration is a water droplet moving along a string or other fine structure that has a partially vertical orientation instead of falling and taking a route exactly parallel to gravity.
In a further embodiment a conveyance system is provided that is immediately adjacent to the suspension frame. With this configuration the liquid is conveyed through the conveyance system the liquid volume to be dispensed will not move appreciably and will not require the force of gravity because it does not move. The liquid will simply collect in the temporary containment area which is immediately continuous with the end of the collapsed conveyance system. This area will have a configurable geometry which can be manipulated not limited to shape, size, surface properties or material properties. Further because this area contains the liquid as it is dispensed to will only hold a finite volume which is dictated by but not limited to its structure. The volume of liquid will not be propelled by gravity in this variation of the device. It will still dose a specific quantity of liquid dictated by what the temporary holding area can hold based off adhesion and cohesion properties of the liquid.
The configuration of the various embodiments, namely the connecting structures and temporary suspension area will be such that once volume of liquid has lodged in or on this geometric configuration it will remain in place unless at the intended transfer. The spatial and dimensional orientation at the end of the device will be configured such that a droplet will easily move aided gravity to the very end. By altering the surface area, size, shape material, composition, geometric configuration and other variables of the temporary suspension area it will securely hold specified volume of liquid until brought into close contact with another liquid surface (the eye surface in most cases). The physical properties of but not limited to capillary action and contact angle will facilitate liquid cohesion and adhesion while the liquid is moving from the terminal of the conveyance system to the temporary suspension region. These same physical properties will be utilized as the liquid is transferred to the ocular surface. The droplet will remain suspended even if the device is moved along all axes, even vertical. It is understood by the inventor that there may be many alternative embodiments of the area that contains the droplet or liquid volume as is transferred to the surface of the eye. A wide variety of geometric configurations and surface properties can be utilized to provide a temporary suspension of a small liquid quantity, and the breadth of the claims includes a multitude of configurations, unless expressly limited in scope.
There has always been an important consideration of maintaining sterility or at least trying to minimize contamination of the reservoir containing eye dropper fluids. Once the volume of liquid separates off at the at the nozzle or end of the tubular conveyance system the geometric and other physical properties are configured to facilitate one way movement of the liquid to the temporary suspension area.
The disclosed concepts can be utilized as an attachment for overlaying and extending the components of a commercially available eye drop bottle, as a removable tip that attaches to an eye drop bottle or even as an integrally formed end of the eye drop bottle. In an embodiment that overlays the pre-existing nipple, the device preferably utilizes an elastic material that allows constricts on the preexisting nipple, such as at the base of the nipple and extending upward toward the tip of the nipple. This constriction provides for a continuous conduit from the reservoir, through the preexisting nipple, and out the tip of the attachment to the suspension section.
The integrally positioned piece can fit and secure in the neck of an eye dropper bottle conforming to the existing structures of the reservoir and neck. Not limited to, but in many cases the elastomer will conform around and inside of the circumferential opening of the reservoir to retain the attachment in place. The device is also configured to utilize elastomeric and conjoined nonelastomeric materials found in the native eye dropper bottle. For example, the elastomeric base is lodged in the opening and be held to the geometry of the reservoir by the elastomeric properties. Optimally it would be designed to fit under the same cap that came with the reservoir and just place the plastic dispensing apparatus on most reservoirs.
The eye dropper devices disclosed herein will help to reduce or eliminate the need for positioning of the head of the person or animal receiving the drops. Since the droplet will remain on the end also understood to be the temporary suspension area no matter what orientation the device is in, the droplet can be brought in close approximation to the eye in any orientation. This will eliminate the need for a person to tilt the head back. Whereas the force of gravity aided the transference of the volume of liquid to the temporary suspension area the properties of said structure overcome gravity and hold the liquid fast.
The end of the apparatus or temporary suspension domain is configured such that the surface area, geometry and physical make up will “attract” the droplet enough it will stay in place. The end may also have deep groves (the temporary suspension area) in the end to create favorable contact angles with the droplet surface and thus hold it better. When brought near the wet surface of the eye it will “jump” or readily transfer by cohesion forces between the liquid applied and the liquid on the eye. Because the droplet can be applied in all orientations and the device is configured to have minimal profile a user could instill it under direct observation, for instance application could take place using the wall mirror in the bathroom under direct vision of the user.
If the droplet did fall back toward the opening at the end of the terminal conveyance system, the geometry will preferably be configured such that it will be directed toward the periphery of the device. This will minimize the chance for contamination of the reservoir.
The device described herein may also have color or other configurations not limited to geometry, materials, or structure which will allow users to easily visualize the droplet when suspended on the end of the device. This may include using the refractive properties of the liquid, or other refractive materials integrated into the device such as silicone or fiber optic materials but not limited to these materials. For instance, the temporary suspension area may contain but not limited to a color which will be refracted through a transparent volume of liquid serving assist the user in indicating the presence of liquid in this area.
The eye drop applicator and or attachment can further include a removable cap intended to protect the device from the environment and thereby reduce the risk of contamination. This cap could also facilitate placement of the device on a bottle by giving the user some extra leverage. Alternatively, the device could be removed from the original reservoir and the original cap reapplied.
In a preferred embodiment of this device the intrinsic elastomeric properties will be used to secure existing device to the reservoir. An elastomeric material will be utilized to form an overlay over the portion that was covered by the original cap, and this includes the threads on most eye dropper bottles. Moreover, the overlay portion that encapsulates the threads of most bottles is configured to be inverted to facilitate easy application. An illustration of this is having an undersized silicone component relative to the dispensing apparatus of the eye dropper bottle which would stretch to fit over the native dispensing terminus, threads, and neck of the original bottle. This elastomeric material would then overlay and grip to the native threads or other structures on an eye dropper bottle thus securing it well. The device is preferably configured to be one continuous elastomer from the suspension frame the base that secures it to the other components of the reservoir. The elastomeric properties and geometric configuration this device will readily adapt to different sizes and configurations of reservoir.
In the following description and the figures, like elements are identified with like indications materials and the use of “e.g.” “etc.” and “or” indicates non-exclusive alternatives without limitation unless otherwise noted. The use of “including” means “including but not limited to” unless otherwise noted.
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Still other features and advantages of the presently disclosed and claimed inventive concept(s) will become readily apparent to those skilled in this art from the following detailed description describing preferred embodiments of the inventive concept(s), simply by way of illustration of the embodiments contemplated by carrying out the inventive concept(s). As will be realized, the inventive concept(s) is capable of modification in various obvious respects all without departing from the inventive concept(s). Accordingly, the drawings and description of the preferred embodiments are to be regarded as illustrative in nature, and not as restrictive in nature.
This application claims the benefit of U.S. Provisional Patent Application No. 63/300,211, filed Jan. 17, 2022, and U.S. Provisional Patent Application No. 63/370,345, the disclosure of each of which is incorporated by reference.
Number | Name | Date | Kind |
---|---|---|---|
2626606 | Campbell | Jan 1953 | A |
3788528 | Ogle | Jan 1974 | A |
4471890 | Dougherty | Sep 1984 | A |
4605398 | Herrick | Aug 1986 | A |
4927062 | Walsh | May 1990 | A |
5007905 | Bauer | Apr 1991 | A |
5040706 | Davis | Aug 1991 | A |
5059188 | Goddard | Oct 1991 | A |
6041978 | Hagele | Mar 2000 | A |
6197008 | Hagele | Mar 2001 | B1 |
6869421 | Hanley | Mar 2005 | B2 |
7527613 | Gaynes | May 2009 | B2 |
7563256 | Hearne | Jul 2009 | B2 |
7758553 | Poisson | Jul 2010 | B2 |
7846140 | Hagele | Dec 2010 | B2 |
8287505 | Pine | Oct 2012 | B2 |
8496635 | Katayama | Jul 2013 | B2 |
9681729 | Geiger | Jun 2017 | B2 |
D852351 | Alvino | Jun 2019 | S |
10695216 | Song | Jun 2020 | B2 |
20050049562 | Cress | Mar 2005 | A1 |
20060116649 | Hagele | Jun 2006 | A1 |
20100006600 | Dascanio | Jan 2010 | A1 |
20160270956 | Lin | Sep 2016 | A1 |
20170266043 | Orloff | Sep 2017 | A1 |
20190060111 | Lin | Feb 2019 | A1 |
20210030589 | Enemark | Feb 2021 | A1 |
20210221575 | Pharma | Jul 2021 | A1 |
20220388737 | Gamboa Burgos | Dec 2022 | A1 |
Number | Date | Country |
---|---|---|
2019166228 | Oct 2019 | JP |
2005074543 | Aug 2005 | WO |
2014055676 | Apr 2014 | WO |
Number | Date | Country | |
---|---|---|---|
20230225902 A1 | Jul 2023 | US |
Number | Date | Country | |
---|---|---|---|
63370345 | Aug 2022 | US | |
63300211 | Jan 2022 | US |