Claims
- 1. A fast dissolving tablet which contains an effective amount of an active ingredient and a water-soluble carbohydrate, and having
- (1) a porosity of 30 to 70%,
- (2) a hardness of 3 to 20 kg, and
- (3) a falling impact strength of 0 to 70%, which tablet is produced from a composition to be compression-molded comprising said active ingredient, 30 to 80% by weight of said water-soluble carbohydrate having a mean particle size of 20 to 70 .mu.m, and 1 to 3% by weight of water, said weights based on the composition to be compression-molded, by a process comprising the steps of adhering particles of said carbohydrate to each other by moistening the surfaces of said particles with said water in the composition, molding the composition at a pressure of 5 to 130 Kg/cm.sup.2, and removing said water.
- 2. A fast dissolving tablet obtainable by compression-molding a composition comprising an active ingredient, 30 to 80% by weight of a water-soluble carbohydrate having a mean particle size of 20 to 70 .mu.m and 1 to 3% by weight of water into a tablet form at a pressure of 5 to 130 Kg/cm.sup.2 and drying the compression-molded tablet, said fast dissolving tablet having
- (1) a porosity of 30 to 70%,
- (2) a hardness of 3 to 20 kg, and
- (3) a falling impact strength of 0 to 70%.
- 3. A fast dissolving tablet according to claim 2 which has a porous structure with a porosity of 30 to 70%, a hardness of 3 to 20 kg and a disintegration time of 0.05 to 3.0 minutes.
- 4. A fast dissolving tablet according to claim 2 which has a porous structure with a porosity of 30 to 70%, a hardness of 3 to 20 kg, a disintegration time of 0.05 to 3.0 minutes, a falling impact strength of 0 to 70% and buccal solubility of 0.05 to 3.0 minutes.
- 5. A fast dissolving tablet according to claim 2 which contains 0.05 to 90% by weight of said active ingredient and 10 to 90% by weight of said carbohydrate.
- 6. A fast dissolving tablet according to claim 1 which contains at least one member selected from the group consisting of a vitamin, a crude drug, an antipyretic-analgesic-antiinflammatory agent, an antianxiety drug, a hypnotic-sedative agent, a stomach-digestive agent, an intestinal function-controlling agent, an antacid, an antitussive-expectorant, an antihypertensive drug, an antidiabetic agent, a drug for osteoporosis and a skeletal muscle relaxant as said active ingredient.
- 7. A fast dissolving tablet according to claim 2 which contains at leat one member selected from the group consisting of sugar, starch sugars, lactose, honey, sugar alcohols and tetroses as said carbohydrate.
- 8. A fast dissolving tablet according to claim 2 which contains at least one member of additives selected from the group consisting of disintegrators, binders, acids, foaming agents, artificial sweeteners, flavorants, lubricants and colorants.
- 9. A fast dissolving tablet according to claim 2 which contains an effective amount of said active ingredient, 10 to 90% by weight of water-soluble carbohydrate and has a porous structure with a porosity of 20 to 80%.
- 10. A fast dissolving tablet according to claim 9 which contains 0.1 to 10% by weight of said active ingredient and 50 to 85% by weight of said water-soluble carbohydrate.
- 11. A fast dissolving tablet according to claim 9 which contains 10 to 30% by weight of said active ingredient and 30 to 80% by weight of said water-soluble carbohydrate.
- 12. A fast dissolving tablet according to claim 9 which contains 30 to 70% by weight of said active ingredient and 15 to 75% by weight of said water-soluble carbohydrate.
- 13. A fast dissolving tablet according to claim 2 obtainable by compression-molding a composition comprising an effective amount of said active ingredient, water-soluble carbohydrate and 0.3 to 7% by weight of water into a tablet form at a pressure of 5 to 130 Kg/cm.sup.2 and drying the resulting tablet.
Priority Claims (1)
Number |
Date |
Country |
Kind |
4-013511 |
Jan 1992 |
JPX |
|
Parent Case Info
This application is a continuation of now abandoned application Ser. No. 08/010,398, filed Jan. 28, 1993.
US Referenced Citations (5)
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Entry |
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Continuations (1)
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Number |
Date |
Country |
Parent |
10398 |
Jan 1993 |
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