FEASIBILITY STUDY--TAXOL FROM PLANT CELL CULTURE

Information

  • Research Project
  • 3492903
  • ApplicationId
    3492903
  • Core Project Number
    R43CA055456
  • Full Project Number
    1R43CA055456-01
  • Serial Number
    55456
  • FOA Number
  • Sub Project Id
  • Project Start Date
    8/1/1991 - 33 years ago
  • Project End Date
    1/31/1992 - 33 years ago
  • Program Officer Name
  • Budget Start Date
    8/1/1991 - 33 years ago
  • Budget End Date
    1/31/1992 - 33 years ago
  • Fiscal Year
    1991
  • Support Year
    1
  • Suffix
  • Award Notice Date
    8/1/1991 - 33 years ago
Organizations

FEASIBILITY STUDY--TAXOL FROM PLANT CELL CULTURE

DESCRIPTION: (Adapted from applicant's abstract): The long term objective of this application is to produce taxol in bulk using a plant cell culture process. Previously proven as well as novel productivity-enhancement strategies will be developed in a comprehensive and integrated manner. The specific aim of phase I research is to establish the feasibility of using plant cell cultures for taxol production by accomplishing four enabling objectives: (1) Transfer of productivity from callus to suspension will be verified. (2) Over 200 cell lines will be screened for taxol and other taxanes. (3) Conditions favoring rapid growth will be established. (4) Kinetics of growth and product formation will be studied.

IC Name
NATIONAL CANCER INSTITUTE
  • Activity
    R43
  • Administering IC
    CA
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    395
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    ET
  • Study Section Name
    Experimental Therapeutics Subcommittee 2
  • Organization Name
    PHYTON CATALYTIC, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    ITHACA
  • Organization State
    NY
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    14850
  • Organization District
    UNITED STATES