TREA

Ferrite vascular contrast media

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Information

  • Patent Grant
  • 4101646
  • Patent Number
    4,101,646
  • Date Filed
    Wednesday, May 10, 1972
    52 years ago
  • Date Issued
    Tuesday, July 18, 1978
    46 years ago
Information
Abstract
Vascular X-ray contrast media comprise ferrite powder coated with a negatively charged colloid such as silicate colloid, gold colloid, silver colloid or platinum colloid. Such media can be used for the medical X-ray diagnosis of small blood vessels. By applying an external magnetic field, the media can be maintained in the vessel or organ being examined.
Description
Claims
  • 1. A water dispersible composition for the preparation of a vascular radiographic contrast media, said composition comprising 20 to 50 parts by weight of at least one magnetic ferrite having a particle size of from about 0.05 to about 1 .mu. coated with from 80 to 50 parts by weight of a negatively charged colloid selected from the group consisting of colloidal gold, colloidal silver iodide, colloidal platinum and colloidal silicate.
  • 2. A composition according to claim 1, wherein the magnetic ferrite is selected from the group consisting of copper-zinc ferrite, nickel-zinc ferrite, manganese-zinc ferrite, zinc ferrite, magnesium ferrite, .alpha.-ferric oxide and ferrosoferric oxide.
  • 3. A contrast media comprising a composition according to claim 1, dispersed in a pharmaceutically acceptable aqueous carrier.
  • 4. A contrast media according to claim 3 wherein the ratio by weight of composition to carrier is 30 to 50 : 70 to 50.
Priority Claims (1)
Number Date Country Kind
45-40656 May 1970 JPX
CROSS-REFERENCE

This is a continuation-in-part of Ser. No. 46,913 filed June 17, 1970, now abandoned.

US Referenced Citations (1)
Number Name Date Kind
3592185 Frei et al. Jul 1971
Non-Patent Literature Citations (1)
Entry
Whistler, Industrial Gums, Academic Press Inc., New York, (1959), p. 63.
Continuation in Parts (1)
Number Date Country
Parent 46913 Jun 1970