Fiber Delivery of CO2 Lasers for Laryngeal Carcinoma

Information

  • Research Project
  • 6786905
  • ApplicationId
    6786905
  • Core Project Number
    R43CA108006
  • Full Project Number
    1R43CA108006-01
  • Serial Number
    108006
  • FOA Number
  • Sub Project Id
  • Project Start Date
    5/7/2004 - 20 years ago
  • Project End Date
    10/31/2004 - 19 years ago
  • Program Officer Name
    WU, ROY S
  • Budget Start Date
    5/7/2004 - 20 years ago
  • Budget End Date
    10/31/2004 - 19 years ago
  • Fiscal Year
    2004
  • Support Year
    1
  • Suffix
  • Award Notice Date
    5/7/2004 - 20 years ago
Organizations

Fiber Delivery of CO2 Lasers for Laryngeal Carcinoma

DESCRIPTION (provided by applicant): The objective of this SBIR proposal is to improve the treatment options for laryngeal carcinoma by developing a fiber enabled CO2 laser system for laryngeal minimally invasive surgery. Current treatments involve radiotherapy, chemotherapy, and surgical procedures either through open surgery or through a laryngoscope. The surgeon has several operating tools at his disposal. These include cold steel surgical instruments, as well as laser beams, which can be used through the laryngoscope. The CO2 laser is the predominant laser tool for these types of surgeries. There is currently no adequate fiber for delivering CO2 laser for these medical procedures. Accordingly, CO2 laser systems utilize rigid lens and mirror systems to deliver the laser beam to the treated tissue. Introduction of a fiber enabled CO2 laser system will enable tangential cutting, easier manipulation of tissue, higher precision, and most importantly, the ability to reach previously inaccessible tissue, for example in the lower airway. While several different fibers have been tried for CO2 laser delivery, including chalcogenide, polycrystalline and hollow-core metal-coated fibers, none of them have been able to fulfill the entire set of specifications for this application. OmniGuide Communications (OGCI) has developed a new approach for the fabrication of photonic bandgap fibers, based on technology it has exclusively licensed and transferred from MIT. In this Project (Phase I and II) OGCI will leverage its unique technology to develop a fiber that will meet the specifications for laryngological surgery. Phase I will focus on the development of a prototype fiber. Phase II will focus on system integration. Our commercial front, OGCI will collaborate with Lumenis, the world leader in medical laser systems. Our academic partners include both MGH and MEEI. The final goal of this Project is to bring a fiber enabled CO2 laser system for laryngology to market.

IC Name
NATIONAL CANCER INSTITUTE
  • Activity
    R43
  • Administering IC
    CA
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    143089
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    395
  • Ed Inst. Type
  • Funding ICs
    NCI:143089\
  • Funding Mechanism
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    OMNIGUIDE, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    CAMBRIDGE
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    02139
  • Organization District
    UNITED STATES