Patent Application
20110136647
This invention relates generally to centrifuge rotors and, more particularly, to high-speed centrifuge rotors to be used with swing buckets.
Centrifuge rotors are typically used in laboratory centrifuges to hold samples during centrifugation. While centrifuge rotors may vary significantly in construction and in size, one common rotor structure is a swing bucket rotor having a solid rotor body defining an outer rim or wall of the rotor, and a plurality of wells or bays in a number such as two, four, or six for example, distributed radially within the rotor body and arranged symmetrically about an axis of rotation. The presence of the outer rim or wall provides structural rigidity to the rotor, especially in view of the high dynamic forces experienced during centrifugation. Buckets are placed in the wells, and are configured to hold sample tubes or similar laboratory-type containers, each containing a particular fluid material. During high-speed rotation, the buckets are permitted to swing within the wells, with the attained generally horizontal orientation of the buckets facilitating radially outward movement of the material held in the tubes.
One conventional type of swing bucket centrifuge rotor includes a generally metallic rotor configured to support an even number of swing buckets, such as four, six, or eight, for example, on diametrically opposite sides of the rotational axis of the rotor. In rotors of this type, and because of the very high rotational speeds during centrifugation, the rotor bodies must be able to withstand the dynamic stresses and forces generated by the rapid rotation of the swing buckets about the central rotational axis. These dynamic stresses and forces may lead to failure of the metallic rotor, such as fatigue failure. Additionally or alternatively, conventional metallic rotors of this type are subject to corrosion and stress fatigue. Finally, the generally solid construction of conventional rotors results in rotors that are relatively heavy and which may be expensive to manufacture. A need therefore exists for improved swing bucket rotors that overcome these and other drawbacks of conventional centrifuge rotors.
The present invention overcomes the foregoing and other shortcomings and drawbacks of centrifuge rotors heretofore known for use for centrifugation. While the invention will be discussed in connection with certain embodiments, it will be understood that the invention is not limited to these embodiments. On the contrary, the invention includes all alternatives, modifications, and equivalents as may be included within the spirit and scope of the invention.
In one embodiment, a centrifuge rotor is provided having a rotor core that defines a rotational axis of the rotor. A plurality of bucket supports is arranged about the axis of rotation. The rotor includes first and second straps. The first strap extends around a first pair of diametrically-opposed ones of the bucket supports for restricting outward movement of the first pair of bucket supports relative to the rotor core. The second strap extends around a second pair of diametrically-opposed ones of the bucket supports for restricting outward movement of the second pair of bucket supports relative to the rotor core. The first and second straps intersect one another at a location through the axis of rotation of the rotor. The rotor may include a plurality of elongate arms extending from a central portion of the rotor core, with each of the bucket supports being located at a longitudinal end of one of the elongate arms. The rotor may be such that each bucket support has first and second trunnions, with each of the trunnions being respectively configured to support a bucket, and with each of the bucket supports defining an outer perimeter of the rotor.
The first and second straps may be made of a high tensile-strength fiber material. For example, the first and second straps may be made of carbon fiber, an aramid fiber, a polyolefin fiber, or the like. Moreover, the first and second straps may be a composite material in which the fibers are encapsulated in a resin, such as a thermoplastic resin or a thermosetting resin. A composite of carbon fibers in a thermosetting material is only an example. The first strap may define a first loop and the second strap may define a second loop, with the second loop being larger than the first loop. In a specific embodiment, the first strap is located completely within the second loop at the location of intersection of the first and second straps with one another. Alternatively or additionally, the second strap may have an upper surface that extends in a curved plane intersecting the second pair of diametrically-opposed ones of the bucket supports. At least one of the first or second pairs of diametrically-opposed bucket supports may include respective grooves for respectively receiving the first or second strap therein.
In a specific embodiment, each of the bucket supports includes first and second segments that are arranged in a suitably-chosen shape, such as a generally V-shape, a generally T-shape, or a generally Y-shape, for example, with the first and second segments respectively including the first and second trunnions. Each of the first and second trunnions may be oriented at an acute angle relative to an adjacent one of the first or second straps. The first and second straps, in one embodiment supporting four buckets, are oriented substantially orthogonal to one another. The rotor may include a rotor hub that is coupled to the rotor core and which is configured for engagement by a centrifuge spindle. The rotor hub is coupled to the rotor core at locations circumferentially spaced from the first and second straps.
In another embodiment, a centrifuge rotor is provided. The rotor has a rotor core that defines an axis of rotation of the rotor, and a plurality of bucket supports each arranged about the axis of rotation. Each bucket support has first and second trunnions, with each trunnion respectively configured to support a bucket. The rotor includes first and second straps oriented generally orthogonal to one another. The first strap extends around a first pair of diametrically-opposed ones of the bucket supports for restricting outward movement of the first pair of bucket supports relative to the axis of rotation. The second strap extends around a second pair of diametrically-opposed ones of the bucket supports for restricting outward movement of the second pair of bucket supports relative to the rotor core. The first and second straps intersect the axis of rotation.
In yet another embodiment, a method is provided for making a centrifuge rotor. The method includes arranging a plurality of bucket supports around a rotor core, with the rotor core including an axis of rotation. The method includes coupling a first strap to a first pair of diametrically-opposed ones of the bucket supports to restrict outward movement of the first pair of diametrically-opposed ones of the bucket supports relative to the rotor core. The first strap intersects the axis of rotation of the rotor. The method includes coupling a second strap to a second pair of diametrically-opposed ones of the bucket supports, and arranging the first and second straps such that they intersect one another at the location of intersection of the first strap and the axis of rotation.
The above and other objects and advantages of the present invention shall be made apparent from the accompanying drawings and the description thereof.
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and, together with a general description of the invention given above, and the detailed description given below, serve to explain the invention.
The rotor 10 includes a plurality of bucket supports 20a, 20b that are arranged for rotation about the axis 14. While the figures illustrate the exemplary bucket supports 20a, 20b being generally V-shaped, it is contemplated that they may alternatively be shaped differently, such as being generally T-shaped or generally Y-shaped, for example, or have any other shapes. The particular arrangement of the bucket supports 20a, 20b is such that each of the bucket supports 20a, 20b supports two of the buckets 12. More specifically, each bucket support 20a, 20b includes a pair of segments 22, 24, each having at a longitudinal end thereof a trunnion or pin 22a, 24a (
The bucket supports 20a, 20b define an outer perimeter of the rotor 10, as illustrated in
With particular reference to
With continued reference to
Those of ordinary skill in the art will readily appreciate that the acute angle illustrated in the figures is merely exemplary rather than limiting, insofar as other acute angles are contemplated. More specifically, the acute angle in this embodiment is about 45 degrees, by virtue of the specific arrangement of the four bucket supports 20a, 20b and the four buckets 12 supported by the bucket supports 20a, 20b. The present disclosure contemplates other embodiments having buckets 12 (and buckets supports 20a, 20b) in other numbers, such as two, six or eight, for example. In alternative embodiments having six or eight buckets 12, the respective acute angles defined by the orientation between the trunnions 22a, 24a and an adjacent strap 36, 38 are larger than about 45 degrees. Similarly, in embodiments having two buckets 12, the acute angle is smaller than about 45 degrees. Likewise, the number of straps in such alternative embodiments may be different from the exemplary two straps 36, 38 of the embodiment illustrated in the figures and still fall within the scope of the present disclosure.
Each of the straps 36, 38 is made of a light, yet strong material, such as fibrous material, a non-fibrous material, a composite material, or others, for example. In the embodiment shown in the figures, the straps 36, 38 are made of high-strength carbon fiber in a thermosetting resin, although this is merely exemplary rather than intended to be limiting. Suitable alternatives include other coated or uncoated high tensile-strength fibers. For example, and without limitation, such alternatives may include a carbon fiber in a thermoplastic resin, or an uncoated carbon fiber. In this regard, the straps 36, 38 may be formed, for example, by winding thermoplastic or thermosetting resin-coated filaments or strands of carbon fiber around the respective pairs of diametrically opposed bucket supports 20a, 20b and then applying pressure and heat to mold the strands into a unitary structure. Especially when the fiber is coated with a thermoplastic resin or a thermosetting resin, the resin may be allowed to cure for a predetermined length of time, so as to make it integral with other portions of the rotor 10. Each of the straps 36, 38 is wrapped around respective pairs of the bucket supports 20a, 20b, as illustrated in the figures, to thereby resist outward movement of the bucket supports 20a, 20b away from rotor core 16 during high-speed rotation. Each of the straps 36, 38 is respectively positioned over and supported by the elongate members 31, 33 of the rotor core 16.
Moreover, each of the bucket supports 20a, 20b includes a groove 40 (
The first and second straps 36, 38 are arranged in the rotor 10 so as to respectively define first and second loops, with the first loop being smaller than the second loop. More specifically, the first strap 36 defines a first loop that is smaller, in the vertical direction of the figures, than the second loop corresponding to the second strap 38. In this regard, the shape and dimensions of the first loop are also determined by the shape and dimensions of the first elongate member 31, while the shape and dimensions of the second loop are determined by the shape and dimensions of the second elongate member 33 of rotor core 16. This dimensional relationship of the straps 36, 38 facilitates their placement at the central portion 16a of rotor core 16. In this regard, the straps 36, 38 intersect one another at the location of central portion 16a that is also intersected by the axis of rotation 14. At the location of intersection of the straps 36, 38, the second strap 38 surrounds the first strap 36 such that the first strap 36 is completely within the second loop defined by the second strap 38.
Those of ordinary skill in the art will readily appreciate that the precise arrangement of the straps 36, 38 at the central portion 16a of rotor core 16 is merely exemplary rather than limiting. In this regard, it is contemplated that the straps 36, 38 may be formed from different sizes of tow or unidirectional tape, made for example and without limitation, of carbon fiber, Kevlar, or glass, such that the respective strands of the first and second straps 36, 38 are intertwined (i.e., interlaced) with one another. Such alternative arrangement would thus result in first and second loops that are not necessarily different in size relative to one another. While this embodiment specifically describes a rotor 10 having straps 36, 38 made of carbon fiber, it is contemplated that, alternatively, the straps 36, 38 may be made of other fibrous or non-fibrous high tensile-strength materials, so long as they provide the required structural integrity to the rotor 10.
Each of the straps 36, 38 includes a respective upper surface 36a, 38a. The upper surface 38a of the second strap 38 lies generally in a slightly curved plane in the span between the two bucket supports 20b to which the second strap 38 is coupled. The upper surface 36a of the first strap 36 also lies in a slightly curved plane in the span between the two bucket supports 20a to which the first strap 36 is coupled, but to a lesser extent than the upper surface 38a of strap 38. Moreover, in the illustrated embodiment, the second strap 38 is embedded within each of a pair of the grooves 40 of bucket supports 20b such that the plane in which the upper surface 38a lies also intersects the bucket supports 20b, specifically an upper surface 20c thereof. The second strap 38 in this embodiment is slightly raised in the portion of strap 38 proximate the central portion 16a of rotor core 16, to thereby accommodate the first strap 36 at the central portion 16a. These dimensional relationships define a rotor 10 that is simple to manufacture and is less bulky than conventional rotors. The slight raise of the second strap 38 is facilitated by a correspondingly greater height of the elongate member 33 relative to other portions thereof proximate the central portion 16a.
With particular reference to
In use, and with particular reference to
While various aspects in accordance with the principles of the invention have been illustrated by the description of various embodiments, and while the embodiments have been described in considerable detail, they are not intended to restrict or in any way limit the scope of the invention to such detail. The various features shown and described herein may be used alone or in any combination. Additional advantages and modifications will readily appear to those skilled in the art. The invention in its broader aspects is therefore not limited to the specific details, representative apparatus and methods and illustrative examples shown and described. Accordingly, departures may be made from such details without departing from the scope of the general inventive concept.
