1. Field of the Invention
The present invention relates to cartilage repair or replacement, and, more particularly, to an orthopedic device for repairing a cartilage defect and a method for utilizing the same.
2. Description of the Related Art
Skeletal joints include articular cartilage to reduce friction, to impart flexibility, and to cushion the impact between opposing articular surfaces. Articular cartilage that becomes damaged may be unable to perform these functions, thereby resulting in pain and restricted motion of the joint. Cartilage may become damaged due to aging, traumatic injury, degenerative disease, such as osteoarthritis, or inflammatory disease, such as rheumatoid arthritis. Once damaged, articular cartilage has a limited ability to heal on its own because it lacks a blood supply. Therefore, devices and methods for repairing cartilage defects are extremely important for relieving pain and restoring motion of the joint.
Various techniques have been developed to relieve pain and restore motion in skeletal joints. Typically, the ends of the bones forming a joint are cut away and replaced with prosthetic implants. Just like the bone it replaced, the implant itself must have a surface that is capable of interacting with adjacent anatomical structures, such as surrounding cartilage and opposing articular surfaces.
In other cases, when the cartilage defect is small, a patch of replacement cartilage is attached to the bone. This second technique presents its own challenges. For one, it is difficult to attach replacement cartilage to the bone while retaining a surface that is capable of interacting with adjacent anatomical structures. For example, a smooth, elastic polymer may be screwed into the bone, but the head of the screw is now exposed to adjacent anatomical structures. Also, viable cartilage is often sacrificed. In processes such as mosaicplasty and osteochondral autograft transfer, viable cartilage is taken from one area of the body and implanted at the site of the defect. In other cases, viable cartilage must be removed from the site of the defect to produce an evenly-shaped, standard-sized defect to accommodate a standard-sized device.
According to an embodiment of the present invention, the orthopedic device includes an implant securable to a bone. The implant has an exterior substrate. The orthopedic device further includes a bearing portion that extends from the exterior substrate of the implant. The bearing portion has a bearing surface that is capable of articulating against adjacent anatomical structures. This bearing surface includes a plurality of fibers.
According to another embodiment of the present invention, the orthopedic device includes an implant securable to a bone. The implant has an exterior substrate and at least one anchor for securing the implant to a bone. The orthopedic device further includes a bearing portion that extends from the exterior substrate of the implant. The bearing portion has a bearing surface that is capable of articulating against adjacent anatomical structures. This bearing surface includes a plurality of fibers.
According to yet another embodiment of the present invention, a method of repairing a cartilage defect in a bone involves securing a bearing portion to the bone. The bearing portion has a bearing surface that is capable of articulating against adjacent anatomical structures. This bearing surface includes a plurality of fibers.
The design of the present orthopedic device allows for attachment of a bearing portion to bone while retaining a surface that is capable of interacting with adjacent anatomical structures. In addition, the design eliminates the need to remove viable cartilage from other areas of the body, and most importantly, the need to remove viable cartilage from areas surrounding the defect. The defect need not be evenly-shaped nor standard-sized. Also, the design of the present orthopedic device allows for implantation into subchondral bone, which may stimulate the production of fibrocartilaginous tissue. In turn, this fibrocartilaginous tissue may interdigitate with the bearing portion of the orthopedic device, which would help to repair the defect and help to secure the orthopedic device in place. The bearing portion may also contain lubricants to promote interaction with fibrocartilaginous tissue and adjacent anatomical structures. Further, the method of the present invention may be performed arthroscopically. Minimally invasive procedures often reduce recovery time and increase the rate of surgical success.
The above-mentioned and other features and advantages of this invention, and the manner of attaining them, will become more apparent and the invention itself will be better understood by reference to the following descriptions of embodiments of the invention taken in conjunction with the accompanying drawings, wherein:
Corresponding reference characters indicate corresponding parts throughout the several views. The exemplifications set out herein illustrate exemplary embodiments of the invention and such exemplifications are not to be construed as limiting the scope of the invention in any manner.
Referring to
Orthopedic device 10 includes implant 14. Implant 14 includes exterior substrate 16 and is capable of being secured to a bone such as femur 12. Implant 14 may be secured to femur 12 by any method known in the art. In one embodiment of the present invention, illustrated in
According to an exemplary embodiment of the present invention, the attachment between implant 14 and femur 12 may be enhanced by ingrowth of femur 12 bone tissue into a porous implant 14. This exemplary embodiment is described in more detail below.
According to another exemplary embodiment of the present invention, implant 14 may be implanted into subchondral layer 13 of femur 12, which may in turn stimulate the production of fibrocartilaginous tissue, the benefits of which are discussed in more detail below. In the accompanying drawings, the scale of orthopedic device 10 may be exaggerated relative to the scale of femur 12. For example,
According to yet another exemplary embodiment of the present invention, implant 14 may be secured to femur 12 using arthroscopic surgical procedures. Such procedures often reduce a patient's recovery time and increase the rate of surgical success. Implant 14 may be cannulated to permit arthroscopic insertion.
As shown in
Implant 14 may be constructed of any biocompatible material. Implant 14 may be constructed of a resilient material, such as a polymer, specifically, a hydrogel or another hydrophilic polymer, or implant 14 may be constructed of a rigid material, such as ceramic or metal. It is also within the scope of the present invention that implant 14 may be constructed of a variety of materials. For example, implant 14 may transition from a rigid material near substrate 16 to a resilient material away from substrate 16 to reduce the likelihood that implant 14 will become loosened from femur 12. The subchondral surface or end of the implant (i.e., the portion of the implant oriented toward cancellous bone) may be softer than the chondral surface or end of the implant (i.e., the portion of the implant oriented toward the cartilage and/or the surface of the bone) so that the implant may lock into the cancellous bone and not be readily removed or pulled out by suction or similar force. Similarly, anchor 18 of implant 14 may be constructed of any biocompatible material. In an exemplary embodiment, because anchor 18 is designed for attachment to femur 12, anchor 18 will be constructed of a rigid material, such as ceramic or metal. Implant 14 and/or anchor 18 may be configured to swell upon implantation into femur 12 to enhance fixation to femur 12.
Metals that may be used to form implant 14 and anchor 18 include, but are not limited to, titanium, a titanium alloy, cobalt chromium, cobalt chromium molybdenum, porous tantalum, or a highly porous biomaterial. A highly porous biomaterial is useful as a bone substitute and as cell and tissue receptive material. As mentioned above, constructing implant 14 and anchor 18 of a highly porous biomaterial may enhance attachment of implant 14 and anchor 18 with femur 12 by the ingrowth of femur 12 bone tissue into implant 14 and anchor 18.
A highly porous biomaterial may have a porosity as low as 55, 65, or 75 percent and as high as 80, 85, or 90 percent, by volume. An example of such a material is produced using Trabecular Metal™ technology generally available from Zimmer, Inc., of Warsaw, Ind. Trabecular Metal™ is a trademark of Zimmer Technology, Inc. Such a material may be formed from a reticulated vitreous carbon foam substrate which is infiltrated and coated with a biocompatible metal, such as tantalum, by a chemical vapor deposition (“CVD”) process in the manner disclosed in detail in U.S. Pat. No. 5,282,861, the disclosure of which is expressly incorporated herein by reference in its entirety. In addition to tantalum, other metals such as niobium, or alloys of tantalum and niobium with one another or with other metals may also be used.
Generally, the porous tantalum structure includes a large plurality of ligaments defining open spaces therebetween, with each ligament generally including a carbon core covered by a thin film of metal such as tantalum, for example. The open spaces between the ligaments form a matrix of continuous channels having no dead ends, such that growth of cancellous bone through the porous tantalum structure is uninhibited. The porous tantalum may include up to 75%-85% or more void space therein. Thus, porous tantalum is a lightweight, strong porous structure which is substantially uniform and consistent in composition, and closely resembles the structure of natural cancellous bone, thereby providing a matrix into which cancellous bone may grow to provide fixation of implant 14 and anchor 18 to femur 12.
The porous tantalum structure may be made in a variety of densities in order to selectively tailor the structure for particular applications. In particular, as discussed in the above-incorporated U.S. Pat. No. 5,282,861, the porous tantalum may be fabricated to virtually any desired porosity and pore size, and can thus be matched with the surrounding natural bone in order to provide an improved matrix for bone ingrowth and mineralization.
Referring again to
Bearing portion 36 may be constructed of any biocompatible material. In an exemplary embodiment of the present invention, bearing portion 36, or a portion thereof, may be constructed of a resilient polymer material, such as hydrogel, poly ether ether ketone, fiber reinforced poly ether ether ketone, ultrahigh molecular weight polyethylene, crosslinked ultrahigh molecular weight polyethylene, polyether ketone ether ether ketone, polyaryl ether ketone, polyphenylene, polyacrylate, polymethacrylate, or polyurethane, or combinations or modifications therefrom. Generally, a hydrogel is a network of polymer chains that are water-soluble but made insoluble through physical and/or chemical crosslinks. These materials are sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are generally formed from natural or synthetic polymers. Hydrogels may be classified as “superabsorbent” and may contain over 99% water, by weight. In addition, hydrogels may have the ability to swell due to water absorption. Hydrogels may also possess a degree of flexibility very similar to natural tissue, due to their significant water content. Advantageously, utilizing a resilient material for bearing portion 36 reduces wear on adjacent anatomical structures, such as surrounding cartilage 42 and opposing articular surfaces. Bearing portion 36 may also include lubricants to promote interaction with these adjacent anatomical structures.
Referring still to
In an exemplary embodiment, bearing portion 36, including fibers 44, is formed from one or more hydrogels and is substantially free of other polymer materials. In another exemplary embodiment, bearing portion 36 including fibers 44, comprises at least about 25% by weight of one or more hydrogels. In still another exemplary embodiment, bearing portion 36 including fibers 44, comprises at least about 50% by weight of one or more hydrogels. And in still another exemplary embodiment, bearing portion 36 including fibers 44, comprises at least about 75% by weight of one or more hydrogels. In still another exemplary embodiment, bearing portion 36 including fibers 44, comprises at least about 95% by weight of one or more hydrogels.
According to an embodiment of the present invention, illustrated in
According to another embodiment of the present invention, illustrated in
According to yet another embodiment of the present invention, fibers 44 of bearing portion 36 may be secured to implant 14 in a variety of ways. For example, first ends 48 of some fibers 44 may be positioned to articulate against adjacent anatomical structures, while middle portion 54 of other fibers 44 may be positioned to articulate against adjacent anatomical structures. In other words, some, but not all, fibers 44 of bearing portion 36 may take the form of looped fibers 52.
Bearing portion 36 may be secured to implant 14 by any method known in the art, such as by press fitting, by injection molding, or by adhering bearing portion 36 to implant 14. Fibers 44 of bearing portion 36 may also aid in the attachment between bearing portion 36 and implant 14. For example, fibers 44 of bearing portion 36 may be press fit or injection molded into substrate 16 of implant 14, as shown in
Bearing portion 36 may also be secured to implant 14 by integrally molding bearing portion 36 with implant 14. Fibers 44 of an integrally molded orthopedic device 10 may be formed in various ways. For example, a single mold may form the shape of both implant 14 and bearing portion 36, including fibers 44. The end result of such a mold would be, for instance, orthopedic device 10 illustrated in
Advantageously, orthopedic device 10 may be designed to accommodate the needs of a particular patient, which could be determined by the size, location, and cause of his or her cartilage defect. In general, the dimensions and density of fibers 44 may be designed to accommodate those needs. The following examples are merely illustrative, as orthopedic device 10, and specifically fibers 44, may be varied in other ways in accordance with the teachings herein. First, diameter 46 of fibers 44 may be varied, as shown by comparing
Also advantageously, without even having to modify its actual design, orthopedic device 10 may accommodate the needs of a particular patient simply by varying the method by which orthopedic device 10 is secured to femur 12. For example, as shown by comparing
While this invention has been described as having preferred designs, the present invention can be further modified within the spirit and scope of this disclosure. This application is therefore intended to cover any variations, uses, or adaptations of the invention using its general principles. Further, this application is intended to cover such departures from the present disclosure as come within known or customary practice in the art to which this invention pertains and which fall within the limits of the appended claims.
This application claims the benefit of Provisional Application No. 61/045,023, filed Apr. 15, 2008, which is incorporated herein by reference in its entirety.
Number | Date | Country | |
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61045023 | Apr 2008 | US |