Claims
- 1. A method of promoting asepsis on mammalian skin, comprising the steps of:
- (1) applying to said skin a film-forming emulsion, comprising:
- a) a substantially water resistant film-forming copolymer phase comprising A, B and C monomers wherein
- A is a monomer wherein the corresponding homopolymer has a glass transition temperature of less than about -15.degree. C., and is present as about 15 to 80% of the total weight of all monomers in the copolymer,
- B is a monomer wherein the corresponding homopolymer has a glass transition temperature of more than about -5.degree. C., and is present as about 20 to 70% of the total weight of all monomers in the copolymer, and
- C is a monomer capable of complexing iodine and delivering it to the skin and is present as about 1 to 15% of the total weight of all monomers in the copolymer;
- b) about 0.05 to 15% of iodine based on total emulsion weight;
- c) an effective amount of an emulsifying agent; and
- d) about 30 to 95% by weight of water; said monomers in the copolymer phase selected such that said emulsion, when applied to human skin in an amount sufficient to form a film having a thickness of about 0.01 mm., dries in less than five minutes to form a film having the properties of
- i) being hydrophobic, as determined by scrubbing the film using light finger pressure with a saline-soaked gauze for at least 40 scrubs with no observable removal of film or loss of iodine color, and
- ii) being capable of elongating at least about 5% before breaking;
- (2) allowing said emulsion to dry to form a film;
- and (3) allowing said film to remain on said skin to promote asepsis.
- 2. A method according to claim 1, additionally comprising the subsequent removal of said film by using a solvent.
- 3. A method according to claim 1, wherein said film is subsequently removed with a surgical drape comprising a pressure-sensitive adhesive layer by contacting said film with said adhesive layer and removing the surgical drape, simultaneously lifting the film from the skin.
- 4. A method according to claim 1, wherein said film is applied to the skin in a thickness that provides a film which, when dry, is about 0.0025 mm to 0.025 mm thick.
- 5. A film-forming emulsion, comprising:
- (a) a substantially water resistant film-forming copolymer phase comprising A, B and C monomers wherein
- A is a monomer wherein the corresponding homopolymer has a T.sub.g of less than about -15.degree. C., and is present as about 15 to 80% of the total weight of all monomers in the copolymer,
- B is a monomer wherein the corresponding homopolymer has a T.sub.g of more than about -5.degree. C., and is present as about 20 to 70% of the total weight of all monomers in the copolymer, and
- C is a monomer capable of complexing iodine and delivering it to the skin and is present as about 1 to 15% of the total weight of all monomers in the copolymer;
- (b) 0.05-15% of iodine based on total emulsion weight;
- (c) 0.1-100% iodate based on added iodine;
- (d) an effective amount of an emulsifying agent; and
- (e) about 30 to 95% by weight of water based on total emulsion weight;
- said monomers in the copolymer phase selected such that said emulsion, when applied to human skin in an amount sufficient to form a film having a thickness of about 0.01 mm., dries in less than five minutes to form a film having the properties of
- i) being hydrophobic, as determined by scrubbing the film using light finger pressure with a saline-soaked gauze for at least 40 scrubs with no observable removal of film or less of iodine color, and
- ii) being capable of elongating at least about 5% before breaking.
- 6. A film-forming emulsion according to claim 5, said inorganic iodate being added as sodium or potassium iodate in an amount by weight of about 1 to 30% based on added iodine.
- 7. A method promoting asepsis on mammalian skin, comprising the steps of
- (1) applying to said skin a film-forming emulsion, comprising:
- (a) a substantially water resistant film-forming copolymer phase comprising A, B and C monomers wherein
- A is a monomer wherein the corresponding homopolymer has a T.sub.g of less than about -15.degree. C., and is present as about 15 to 80% of the total weight of all monomers in the copolymer,
- B is a monomer wherein the corresponding homopolymer has a T.sub.g of more than about -5.degree. C., and is present as about 20 to 70% of the total weight of all monomers in the copolymer, and
- C is a monomer capable of complexing iodine and delivering it to the skin and is present as about 1 to 15% of the total weight of all monomers in the copolymer;
- (b) 0.05-15% of iodine based on total emulsion weight;
- (c) 0.1-100% iodate based on added iodine;
- (d) an effective amount of an emulsifying agent; and
- (e) about 30 to 95% by weight of water based on total emulsion weight;
- said monomers in the copolymer phase selected such that said emulsion, when applied to human skin in an amount sufficient to form a film having a thickness of about 0.01 mm., dries in less than five minutes to form a film having the properties of
- i) being hydrophobic, as determined by scrubbing the film using light finger pressure with a saline-soaked gauze for at least 40 scrubs with no observable removal of film or less of iodine color, and
- ii) being capable of elongating at least about 5% before breaking;
- (2) allowing said emulsion to dry to form a film; and
- (3) allowing said film to remain on said skin to promote asepsis.
- 8. The method of claim 7, wherein said inorganic iodate is added as sodium or potassium iodate in an amount by weight of about 1 to 30% based on added iodine.
Parent Case Info
This is a division of application Ser. No. 07/334,366, filed Apr. 10, 1989, now U.S. Pat. No. 4,978,527.
US Referenced Citations (18)
Foreign Referenced Citations (4)
Number |
Date |
Country |
107277 |
May 1984 |
EPX |
130080 |
Jan 1986 |
EPX |
2557607 |
Jul 1976 |
DEX |
1465190 |
Feb 1977 |
GBX |
Non-Patent Literature Citations (1)
Entry |
Fredell et al "Effect of pH and Water Hardness on the Sanitizing Activity of Five Commercial Iodophors" Journal of Food Protection, vol. 48, No. 7 (558-561) Jul. 1985. |
Divisions (1)
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Number |
Date |
Country |
Parent |
334366 |
Apr 1989 |
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