The present invention refers to a filter for a cartridge containing a particulate material, wherein the filter is intended to permit passage of a liquid through the filter and thus the cartridge, but to prevent passage of the particulate material, wherein the filter permits the liquid to pass through the filter in a filter direction. The present invention also refers to a cartridge arranged to contain a particulate material, wherein the cartridge includes: an inner space for housing the particulate material; an inlet arranged to permit the introduction of a liquid into the inner space; an outlet arranged to permit discharge of liquid from the inner space; and at least a first filter arranged at the outlet and to permit passage of the liquid through the filter, but to prevent passage of the particulate material through the filter, wherein the filter permits the liquid to pass through the filter in a filter direction. Moreover, the present invention refer to a use of a filter in a cartridge containing a particulate material, wherein the cartridge includes: an inner space for housing the particulate material; an inlet arranged to permit the introduction of a liquid into the inner space; an outlet arranged to permit discharge of liquid from the inner space; and at least one filter arranged at the outlet and to permit passage of the liquid through the filter but to prevent passage of the particulate material through the filter, wherein the filter permits the liquid to pass through the filter in a filter direction. The present invention also refers to a system for preparing a liquid solution for a medical procedure.
In a dialysis equipment, it is known to use such a cartridge for the supply of different substances to the dialysis liquid, see EP-B-278 100. The particulate material contained in the cartridge may include various substances to be supplied to the dialysis liquid, such as sodium bicarbonate, sodium chloride and other salts. In use, the dialysis liquid is flowing through the cartridge, wherein the particulate substance is successively dissolved and thus added to the dialysis liquid. Consequently, the general purpose of the filter is to permit the passage of the dialysis liquid together with a dissolved quantity of the substance, but to prevent the passage of any particles of the particulate material. If such particles of the substance are contained in the dialysis liquid, sensible parts of the dialysis equipment, such as pumps, may be damaged.
The filter used today in such a cartridge is made of a fibre material, such as polypropylene, in the form of a woven filter net. Such a filter is flexible, and thus not self-supporting. The filter, therefore, has to be supported by a supporting component, for instance in the form of a support plate. The filter is mounted to the support plate in a position adjacent to the support plate, wherein the filter and support plate form a common unit that is mountable in the cartridge. The manufacture of such a filter unit is relatively complicated and expensive, since the manufacture includes the separate steps of manufacturing the woven filter, manufacturing the support plate and joining the filter and the plate to each other. Moreover, it is difficult to obtain exactly the desired permeability for such a filter. In particular, the permeability frequently is to high, which involves a risk for formation of channels in the particulate material contained in the cartridge.
Another problem which may occur with the cartridges used today is that the particulate material may escape from the cartridge through the inlet and the outlet before the cartridge is actually used, especially via the inlet during the initial priming operation. In order to reduce this risk of escape, a felt pad or any other similar porous member is incorporated in the inlet and the outlet. In particular, during priming from below, via the outlet, the felt pad at the inlet is important. The porous felt pad is normally manufactured in another material than the rest of the cartridge, which is disadvantageous from a recycling point of view.
The object of the present invention is to provide an improved filter for a cartridge containing a particulate material. In particular, it is aimed at a filter, which is inexpensive to manufacture and which demonstrates a uniform and reliable permeability.
This object is achieved by the filter initially defined, which is characterised in that the filter includes at least one slit-shaped opening, which has a first extension and second extension being substantially perpendicular to the filter direction and to the first extension, wherein the second extension is significantly shorter than the first extension.
By such a filter, a uniform flow area of the slit-shaped opening or slit-shaped openings is ensured. Any particles of the particulate material having a minimum size larger than the second extension will be efficiently prevented from passing the filter, and thus from causing any damages to components arranged downstream the filter. Such a filter at the inlet of the cartridge also permits the achievement of a desired pressure drop over the filter. With an appropriate pressure drop a channelling in the particulate material may be avoided. It should also be pointed out that such a filter may be manufactured in an inexpensive manner by means of an injection moulding process.
According to an embodiment of the invention, the second extension is also significantly shorter than the length of the slit-shaped opening in the filter direction. This feature permits a certain thickness of the filter ensuring a sufficient strength of the filter. Consequently, the filter is self-supporting and does not need any support plate to be provided adjacent to the filter, which also contributes to reducing the manufacturing costs.
According to a further embodiment of the invention, the second extension is equal to or less than 0.12 mm, preferably equal to or less than 0.10 mm or 0.08 mm. Moreover, the second extension may be equal to or more than 0.02 mm, preferably equal to or more than 0.04 mm. According to an advantageous embodiment, the second extension is approximately 0.06 mm.
According to a further embodiment of the invention, the filter is made of a polymer material, including one of polypropylene and polycarbonate.
According to a further embodiment of the invention, the filter includes a filter element, wherein the slit-shaped opening extends through the filter element. Advantageously, the filter includes a plurality of such slit-shaped openings, which extend through the filter element. Such filter element may be easily moulded in one single piece. The first extension of each slit-shaped opening may extend in a radial direction towards a centre point of the filter element, providing a plurality of slit-shaped openings in a star-like configuration.
According to a further embodiment of the invention, the filter element has a shape of a substantially plane disc. Such a shape is easy to manufacture and is suitable for the filter at the inlet and the outlet of the cartridge.
According to another embodiment of the invention, the filter element has a conical shape. Such a conical shape is also easy to manufacture and is suitable for the filter at the inlet and the outlet of the cartridge. This conical shape is particularly suitable for the filter at the inlet of the cartridge. The filter may then be mounted in an attachable cover of the cartridge, wherein the tip of the conical filter element is pointing away from the inner space of the cartridge. Liquid may then flow through the slit-shaped openings and on the conical outer surface of the filter element. Moreover, the filter may include a peripheral support portion connected to the filter element and adapted to abut an inner wall of the cartridge. The peripheral support portion may then advantageously have a peripheral surface and include a plurality of ridges projecting from the peripheral surface and adapted to abut the inner wall of the cartridge so that a thin gap is formed between the peripheral surface and the inner wall, said gap providing a further passage for the liquid. In such a way it may be ensured that a sufficient amount of liquid is always present in the cartridge.
According to a further embodiment of the invention, the slit-shaped opening has an first end and a second end, wherein the second extension of the slit-shaped opening increases from a minimum value at one of the ends of the slit-shaped opening to a maximum value at the other end of the opening. Such a shape of the slit-shaped opening or openings is advantageous from a manufacturing point of view. If the first end of the openings faces the inner space of the cartridge and thus the particulate material, the particulate material is efficiently prevented from leaving the cartridge. However, even if the second end faces particulate material a proper functioning of the filter is achieved, i.e. particulate material will be efficiently prevented from leaving the cartridge.
According to another embodiment of the invention, the filter includes a filter element formed by a first disc and a second disc, which are arranged in parallel with each other and separated from each other by an interspace that form the split-shaped opening. Advantageously, the interspace is formed by distance members arranged in the interspace between the discs, each of said distance members having a predetermined height corresponding to the second extension. Furthermore, each of said distance members may include a projection extending from one of the first disc and the second disc. In order to provide said liquid passage through the filter, the first disc may be provided with at least one aperture forming an inlet passage to the interspace, and the second disc with at least one aperture forming an outlet passage from the interspace.
According to a further embodiment of the invention, the filter is made through an injection moulding process.
The object is also achieved by the cartridge initially defined, which is characterised in that the filter includes at least one slit-shaped opening, which has a first extension and a second extension being substantially perpendicular to the filter direction and to the first extension, wherein the second extension is significantly shorter than the first extension.
Advantageous embodiments of the cartridge are defined in the dependent claims 24 to 43.
The object is also achieved by the cartridge initially defined, which is characterised in that the second filter includes at least one slit-shaped opening, which has a first extension and a second extension being substantially perpendicular to the filter direction and to the first extension, wherein the second extension is significantly shorter than the first extension.
Advantageous embodiments of the cartridge are defined in the dependent claims 45 to 60.
Furthermore, the object is achieved by the use of such a filter in such a cartridge, wherein the use includes the step of supplying said liquid to the cartridge in such a way that the liquid passes through particulate material and thereby dissolves at least a part of the particulate material to form a liquid solution. The liquid may be a a dialysis liquid. The particulate material may include bicarbonate, and/or sodium chloride: the particulate material may also include a cleaning substance. A cartridge with such a cleaning substance may be used for instance for cleaning of a dialysis machine.
Furthermore, the object is achieved by the system initially defined, which is characterised in that the filter includes at least one slit-shaped opening, which has a first extension substantially perpendicular to the filter direction and a second extension substantially perpendicular to the filter direction and to the first extension, wherein the second extension is significantly shorter than the first extension. Advantageous embodiments are defined in claims 66 to 69
The present invention is now to be described more closely by the following description of various embodiments and with reference to the drawings attached.
The system includes a source 1 containing a liquid, and in particular a dialysis liquid. The source 1 may be supplied with the liquid via an inlet conduit 2. A first liquid conduit 3 has a first end 4 communicating with the source 1 to withdraw the dialysis liquid into the first liquid conduit 3. The first liquid conduit 3 also has a second end 5 for delivering a dialysis liquid solution to a receiver (not disclosed) such as a dialysis equipment. A second liquid conduit 6 has a first end 7 communicating with the source 1 and a second end 8 communicating with the inlet of a cartridge 9 for the introduction of the liquid from the source 1 into an inner space 10 of the cartridge 9 to produce a concentrate liquid solution. A third liquid conduit 11 has a first end 12 communicating with the outlet of the cartridge 9 and a second end 14 communicating with the first liquid conduit 3 at a mixing point 13 intermediate said first end 4 and said second end 5.
The third liquid conduit 11 is thus arranged to withdraw said concentrate liquid solution from the cartridge 9 into the first liquid conduit 3 to be mixed with the liquid conducted through the first liquid conduit 3 from the source 1 in order to produce a liquid solution for delivery to said receiver. The concentrate liquid solution is transported through the third liquid conduit 11 by means of a pump 15. The liquid is transported from the source 1 to said receiver through the first liquid conduit 3 by means of a pump 16. A control loop 17 including a valve 18 may be arranged to control the quantity of concentrate liquid solution to be delivered to the liquid of the first liquid conduit 3.
The cartridge 9 is explained below with reference to
The cartridge 9 is arranged to contain a particulate material 20 in the inner space 10. In the embodiment disclosed the particulate material 20 is a sodium bicarbonate powder. The cartridge 9 has an inlet 21 which is arranged to permit the introduction of a liquid into the inner space 10. In the embodiment disclosed the inlet 21 is connected to and communicates with the second liquid conduit 6. The cartridge 9 also has an outlet 22 arranged to permit the discharge of liquid from the inner space 10. In the embodiment disclosed, the outlet 22 is connected to and communicates with the third liquid conduit 11 for discharging the concentrate liquid solution.
A first filter 23 is arranged at the outlet 22 to permit passage of said liquid through the filter 23, but to prevent the passage of the particulate material 20 through the filter 23. The filter 23 defines a filter direction x, and thus permits the liquid to pass through the filter 23 in the filter direction x. The cartridge 9 also includes a second filter 24 arranged at the inlet 21 to permit passage of the liquid through the filter 24, but to prevent passage of the particulate material 20 through the filter 24. Also the second filter 24 defines a filter direction x and permits the liquid to pass through the filter 24 in the filter direction x. It is to be noted that according to this invention such a filter 23 is provided at the outlet 22. The provision of the second filter 24 at the inlet 21 is preferable, but not mandatory.
The filters 23 and 24 disclosed in
Preferably, the filters 23 and 24 are identical to each other. Two different embodiments of the filters 23, 24 are explained below with reference to
In accordance with the present invention, the second extension 32 is significantly shorter than the first extension 31. Moreover, the second extension 32 is significantly shorter than the length 33 of the slit-shaped opening 30 in the filter direction x. For instance, the length 33 may be 10-100 times the second extension 32. In particular, the second extension 32 is equal to or less than 0.12 mm, preferably equal to or less than 0.10 mm or even 0.08 mm. Moreover, the second extension 32 is equal to or more than 0.02 mm, preferably equal to or more than 0.04 mm. According to a preferred embodiment, the second extension 32 is approximately 0.06 mm.
The slit-shaped openings 30, which extend through the disc 29, are, in the embodiment disclosed in
The filter 23, 24 includes a circumferential flexible edge portion 36 formed as a part of the disc 29. The edge portion 36 is flexible in an radial inward direction and formed by the provision of a circumferential groove 37 extending radially inside the edge portion 36. Consequently, the flexible edge portion 36 may be bent radially inwardly when the filter 23, 24 is introduced at its position on the shoulder 25, 26 in order to pass the shoulder 27, 28. After having passed the shoulder 27, 28, the flexible edge portion 36 may flex back to the outer position disclosed in
In the second embodiment, the filter direction x extends, in contrast to the first embodiment, in parallel with the discs 41 and 42. The slit-shaped opening 30 is formed by the interspace 44. Consequently, the second extension 32 correspond to the height of each distance member 43.
The first disc 41 includes a number of apertures 46 extending through the first disc 41 and forming outlet passages from the interspace 44. The second disc 44 also includes a number of apertures 47 forming an inlet passage to the interspace 44. The apertures 46 of the first disc 41 are arranged in such a way that they are not positioned opposite any one of the apertures 47 of the second disc 42. More precisely, the apertures 47 are arranged along a radially inner ring and a radially outer ring whereas the apertures 46 are arranged along a ring in an intermediate position between said inner ring and said outer ring. It is to be noted, that the apertures 46, 47 also may be arranged in other positions than the ones disclosed.
The liquid passing through the filter 23, 24 will thus enter the interspace 44 via one of the apertures 47 and flow through the interspace 44 in the filter direction x to one of the apertures 46 of the first disc 41 to be discharged from the filter 23, 24. Since the liquid may flow from an aperture at said outer ring or from an aperture along said inner ring towards an aperture along said intermediate ring, the flow direction in the second embodiment includes all directions in a plane being parallel with the main extension planes of the discs 41, 42. This is indicated by the double arrow x in
The distance members 43 are positioned between the apertures 47 along said inner ring and between the apertures 47 along the said outer ring. More precisely, a distance member 43 is provided between each pair of adjoining apertures along said inner and outer rings.
The first disc 41 also includes a central cavity 48 arranged to receive a central projection 49 of the second disc 42. By means of the cavity 48 and the projection 49 the second disc 42 may be securely positioned in the first disc 41.
Also in this case the second filter 24 defines a filter direction x and permits the liquid to pass through the filter 24 in the filter direction x. The second filter 24 according to the third embodiment is disclosed more closely in
The second filter 24 according to the third embodiment also includes a peripheral support portion 60 connected to a lower end portion of the filter element 29′. The peripheral support portion 60 has a peripheral surface 61 and includes a plurality of longitudinal ridges 62 projecting from the peripheral surface 61 and extending in a longitudinal direction, nearly in parallel to each other. The peripheral surface 61 is nearly cylindrical or slightly conical so that the peripheral surface is somewhat tapering, with a small cone angle, towards the filter element 29′. The peripheral support portion 60 abuts an inner wall 64 of the cartridge 9. More precisely, the longitudinal ridges 62 abut the inner wall 64 of the cartridge 9 in such a way that a thin gap 65 is formed between the peripheral surface 61 and the inner wall 64. The gap 65, which is divided into a plurality of gap portions by the ridges 62, provides a further passage for the liquid. The height of the ridges 62 is selected in such a way that the width of the gap 65 is substantially the same as the length of the second extension 32. In the embodiment disclosed in
The slit-shaped openings 30 of the filter element 29′ of the second filter 24 according to the third embodiment also has a first end and a second end. In the embodiment disclosed the first end is an upstream end and the second end a downstream end with respect to the filter direction x. Moreover, in the embodiment disclosed, the second extension 32 of the slit-shaped opening 30 decreases in the filter direction x from a maximum value at the first, upstream end of the slit-shaped opening 30 to a minimum value at the second, downstream end of the opening 30. Also the second filter 23 and its filter element 29′ according to the third embodiment is made through an injection moulding process.
It is to be noted that the filter according to the third embodiment disclosed in
It is also to be noted that the cartridge may be used in any direction so that the outlet 22 becomes the inlet 21 and the inlet 21 becomes the outlet 22.
The present invention is not limited to the embodiments disclosed but may be varied and modified within the scope of the following claims. In the embodiment disclosed in
Number | Date | Country | Kind |
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0301021-2 | Apr 2003 | SE | national |
Filing Document | Filing Date | Country | Kind | 371c Date |
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PCT/SE04/00557 | 4/7/2004 | WO | 10/7/2005 |
Number | Date | Country | |
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60461659 | Apr 2003 | US |