This invention relates to a medical apparatus, especially a filtering powder medicament inhaler and its application, specifically, an inhaler for either standalone use or for use in conjunction with a powder medicament mouthpiece.
Presently, there are a number of models of dry powder inhalers being used to treat asthma, but the curing rate by the GINA standard is only about 5%. The powder medicament particles for inhalation can easily agglomerate and are difficult to separate. The dosage is low and thus packaging is difficult. Therefore, it is usually mixed with a large amount of lactose, as high as 98.8% of the total volume of dry powder. However, long-term inhalation of lactose can produce side effects. If the amount of the lactose inhalation is to be reduced, the dosage of dry powder has to be reduced, resulting in lower efficacy of treatment.
The object of the present invention is to separate the active powder medicament from dry powder composition to allow quick inhalation of a sufficient dosage and removal of lactose, for enhancing the efficacy.
The object of this invention is realized in the following way: a filtering powder medicament inhaler, comprising of the base (1) and upper base (2); inside the base (1) is provided with a capsule chamber (4), the chamber lower side (81) is a half-moon-shaped groove upward, on both sides of the chamber are provided with triangle piercing knifes (6), respectively provided with pushbutton (5), pushbutton (5a) and return spring; the upper base (2) is pivot mounted on the base (1) via the shaft in the opening (64) on one side, and can close or open with the base (1) with the positioning hook (2a) on the other side; at the mouth of conduit (18) in upper base (2) there is a fence, with the features that:
a) In the upper base (2) there is a separator (62), its lower end is connected with groove (63), the groove lower side (82) is downward half-moon-shaped;
b) The upper base (2) has arranged thereon a hollow tube exterior connector (10) matching a suction tube (131), the hollow tube (19a) and a cavity (9) on one side of the separator (62) are interconnected via conduit (18), or, the hollow tube (19a) is extended for about 8 centimeters to form a mouthpiece;
The upper base (2) has arranged in the cavity (9) thereof a filter (121);
The base (1) is provided with an external base cover (72), with square frames (73) on the façade, which covers a press-button (5a) so as to reduce air flow into the cavity (9), and relatively seal the inhaling conduit and allow for rapid entrainment of powdered medicament.
In this invention, multiple suction tubes including suction tube (131) and suction tube (132) connected with each other are connected to form the mouthpiece, or the suction tube (131) is connected with at least two small suction tubes (131a) to form the mouthpiece; or the inside of suction tube contains a filter (121) including the filter cup, for which the number, shape, size and layers of filtering pores are set as required, for example to stop particles sized over 6 μm.
In this invention: the hollow tube (19a) contains the intubation tube (67), ball (68) and fence.
In this invention: the upper base (2) is provided mouthpiece cover (71), which covers the suction tube (131), on a drug storing chamber (74) is arranged on the mouthpiece cover (71).
Beneficial Results:
The advantage of this invention is: the base cover (72) relatively seals the inhaling conduit, so that the dry powder can be quickly carried out and powder medicament is filtered out when the air flows though the capsule during inhaling, allowing entrainment of sufficient powdered medicament in the first time, with significant efficacy.
In the following, this invention is further described in conjunction with attached drawings.
Embodiment 1 :
A filtering powdered medicament inhaler (
Functions of the separator (62) and groove (63) in upper base (2): 1. separating the cavity in upper base (2) into cavities (7) and (9), so that air stream will carry dry powder mainly from the capsule to cavity (9); (2) pressing the capsule and squeezing the air inside the capsule to both ends, to facilitate piercing; and 3. the hand-contaminated surface of the capsule is pressed by the upper and lower grooves, to avoid contacting with the air stream and dry powder, to prevent cross infection.
Embodiment 2:
A filtering powder medicament inhaler (
In the embodiments, the parts of this invention can be made by injection moulding or with metal and new materials. And the finished parts can be fitted and connected.
Number | Date | Country | Kind |
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2010 1 0596113 | Dec 2010 | CN | national |
Filing Document | Filing Date | Country | Kind | 371c Date |
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PCT/CN2011/084071 | 12/15/2011 | WO | 00 | 6/17/2013 |
Publishing Document | Publishing Date | Country | Kind |
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WO2012/079525 | 6/21/2012 | WO | A |
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Number | Date | Country | |
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20130276783 A1 | Oct 2013 | US |