FIG. 1 is a top perspective view of a flood defense barrier showing my new design; FIG. 2 is an end view thereof, wherein an opposite side end view is a mirror image thereof; FIG. 3 is a top plan view thereof; FIG. 4 is a bottom plan view thereof; FIG. 5 is a front elevational view thereof; FIG. 6 is a rear elevational view thereof; and, FIG. 7 is a bottom perspective view.