Continuation in part of application Ser. No. 12/692,472, filed on Jan. 22, 2010, which is a continuation in part of application Ser. No. 12/201,741, filed on Aug. 29, 2008, issued as U.S. Pat. No. 8,155,273, which is a continuation in part of application Ser. No. 11/355,692, filed on Feb. 16, 2006, now abandoned, all of which are incorporated herein in their entirety.
Provisional application No. 61/801,215, filed on Mar. 15, 2013.
This invention relates in general to the field of radiation sources in which x-rays are produced by accelerated impact on metal anodes and more particularly to an x-ray source having superior conversion efficiency of electrons into x-rays and increased x-ray flux output, as well as to parallel beam x-ray sources formed of arrays of such individual x-ray sources.
This invention provides a source of x-ray flux in which x-rays are produced by e-beams impacting the inner walls of holes or channels formed in a metal anode such that most of the electrons reaching the channel impact an upper portion of said channel. A small portion of the electrons will produce x-rays from this primary impact but most of them will be scattered, mostly in the forward direction of the e-beam trajectory, with the scattered electrons again impacting the walls of the channel and either generating x-rays or scattering, the scattered electrons then repeating the process until most of the electron beam has generated x-rays. A small portion of the beam will not generate x-rays at the channel walls through either primary or secondary (scattered) impact. This portion can impact a thin film of metal disposed across the diameter of the end of the channel, where it will either generate more x-rays or be drained away. The x-rays generated at the channel walls, and those few generated at the exit of the channel exit the channel out an anode window provided at the end of the channel. This anode window may support the thin metal film at the end of the channel.
Since the anode surface which generates x-rays in this source is many times greater than the corresponding surface of either the reflective or a transmission anodes of prior art x-ray sources, which are power limited by the generation of heat from e-beam impact, the disclosed source can also accommodate much higher electron beam current and therefore generate much higher x-ray flux from a given x-ray spot size. The disclosed source has the further advantage of pre-collimation of the exiting x-ray flux by the shape of the channel walls. It has a yet further advantage of hardening the beam, since some of the lower energy x-rays generated at the walls will be absorbed by the walls and higher energy x-rays will exit the channel.
A single channel x-ray source with high conversion efficiency and high power can be made with the disclosed forward flux channel (FFC) x-ray source architecture. This single channel source can be advantageously used in many applications, especially those now served by microfocus x-ray tubes, which commonly use a transmission x-ray target. In another embodiment, an FFC array source can be made with multiple channels in a broad anode plate, each channel receiving an e-beam from a cathode in a cathode array provided opposite the anode plate across the vacuum space of the source. FFC array sources, in linear or X-Y arrays, may be made as flat panels, as curved arrays or in other formats. They may be advantageously used in many other applications, including stationary computed tomography (CT) systems, parallel x-ray beam imaging systems and as wide sources of parallel x-ray pencil beams in phase contrast imaging (PCI) systems, coded aperture imaging systems or dynamically addressed coded source systems. In a further embodiment, the channels may be formed as long slits in the anode, to provide a fan beam of high power x-ray flux.
There is a continuing need for x-ray sources with higher flux levels and power efficiency. Particularly in x-ray imaging systems, an increase in flux power translates directly to a decrease in image acquisition time, to the limit of the detector. In x-ray analytical systems, the speed and scope of the systems is often limited by the flux available from the x-ray source used.
Prior art x-ray tubes with an angled reflective anode target are limited in their power output and efficiency by the fact that when the e-beam hits the anode surface only a small part of it penetrates the target material to generate x-rays; nearly half of the e-beam is scattered off the target back towards the cathode and loses power to make x-rays. Transmission anode x-ray sources have a fundamental limitation in generating x-ray flux in that the target must be a thin metal film to allow transmission of x-rays generated by the voltages used in imaging systems, but this thin film is inherently limited in the amount of heat it can dissipate and the heat it can handle before it melts or peals off the glass, beryllium or other flux exit window on which it is formed. Transmission targets also emit flux in all directions out the source. If collimators are used after the source, they will further diminish the already faint level of x-ray flux.
There are also a number of emerging x-ray imaging modalities which need new x-ray sources. Stationary CT systems, in which x-ray spots are addressed electronically in x-ray sources with multiple x-ray pixel (xel) locations, are being developed as an alternative to conventional CT systems using a classical x-ray tube rotating around a mechanical gantry. Various sources for these systems have been described in the prior art. Medical imaging typically requires e-beam current densities on the anode spot of at least a few A/cm2 at tens of kV electron energies, which is more power than a thin film transmission sources can handle before melting or delaminating. Angled xel array sources, such as those taught by U.S. Pat. No. 6,850,595 and U.S. Pat. No. 7,082,182, can handle higher power loads, but still may suffer anode pitting. Use of an angled target limits these sources to linear 1D xel arrays. Flat reflective anode sources, such as that taught in U.S. Pat. No. 8,155,273 and US 2010/0189223, can provide x-y xel matrixes, but they too would benefit from having a larger surface area over which to distribute the e-beam power.
Imaging systems in which multiple parallel x-ray flux beams pass through an imaging subject to be detected by a corresponding array of x-ray detectors, or an array of areas on a single x-ray detector, would have a number of advantages. More flux power could be generated by the use of multiple anode emission spots, since it is the instantaneous heat load on the anode which is most responsible for pitting or anode overheating. The use of multiple, limited-angle x-ray flux beamlets would also substantially reduce the amount of x-ray scatter in the subject, allowing a reduction in the radiation dose delivered to the subject. The increase in dose now commonly used to account for scatter in the subject, known as the bucky factor, could be cut reduced. With an x-ray source generating 77×77 or so of these x-ray beamlets, for examples, the bucky factor could be reduced by more than half in some imaging applications, such as breast imaging. Prior art sources, however, are not adapted to deliver multiple parallel x-ray beamlets. A flat panel source of the present invention, however, would be well adapted to such use and enable the development of new types of low dose imaging systems.
PCI is an emerging imaging modality which promises major improvements in dose reduction, improved sensitivity in low contrast applications such as breast imaging and high resolution. Prior art x-ray sources, however, are inadequate to make PCI useful for clinical and other large object imaging. Current PCI imaging systems rely on single pencil beams of x-ray flux, which do not cover a clinically meaningful area, or synchrotron radiation sources, which are large, expensive and not available in clinical settings. There has been research into the use of gratings to collimate and spread the flux from x-ray tubes over a wider area, but passing flux from a point source through a grating results in most of the flux from a point source being absorbed in the grating, resulting in unacceptably long image acquisition times. The source of the present invention can provide a highly parallel array of narrow or pencil beams, which can cover a wide area, and can be used with gratings and other PCI system techniques to make PCI available in clinical settings.
Coded source imaging is another new modality which promises high resolution, low noise and therefore low dose. It is possible to place a fixed coded aperture grating in front of an x-ray source and get a coded source but this too will have low flux power and long imaging times. The source of the present invention can be made with fine pitch xels to provide a coded source with high flux power. This source can also be dynamically addressed, for dynamic coded source imaging. This further enables coded source CT by shifting the coded source across a panel or array of panels.
There have been prior attempts to make a forward flux channel x-ray source. U.S. Pat. No. 4,675,890 teaches a rectilinear bore hole source with straight hole walls. Electrons at the high kV energies used in x-ray generation, however, are traveling at relativistic speeds and do not change course easily. Nearly all the electrons would pass straight through a straight channel and not generate x-rays. This prior art source teaches the use of magnets near the anode to deflect the beam into the channel walls, but this would be very hard to do by the time the electrons approach the anode and would require impractically large magnets. U.S. Pat. No. 6,993,115 also discloses forward flux channels in an x-ray anode, but this too has straight walls and relies on space charge spreading to direct some of the electrons into the channel walls. In reality, e-beams that are confined enough to make it from the cathode to the anode and into the channel will not suddenly start spreading due to space charge. Another source architecture, disclosed in U.S. Pat. No. 7,349,525, uses a flat anode disposed at a shallow angle on one side of a channel to receive the incoming electron beam. X-ray flux is then generated at a shallow angle and some of it passes through a collimating channel. While an improvement over prior sources, this source, by having the anode on only one side of the channel does not make use of the scattered portion of the electron beam and will therefore still have limited efficiency and power. It is also a large mechanical assembly, intended for use in a curved linear array of xels for a large stationary CT system and is not adapted for 2D parallel beam imaging, PCI or other of the imaging systems enables by the source of the present invention.
A need therefore exists for forward flux channel x-ray sources with improved power efficiency and power levels, adapted for use as single channel sources and for use in 2D arrays and dense arrays.
It is an object of the invention to provide an x-ray source with superior conversion efficiency of electrons into x-rays and increased x-ray flux output, thereby decreasing image acquisition times i x-ray imaging systems and improving the speed and scope of x-ray analytical systems. It is a further object of the invention to provide a highly collimated source of x-ray flux. Another object of the invention is to enable improved x-ray imaging systems, including CT systems. A yet further object is to enable new imaging modalities such as parallel beam imaging, PCI and coded source imaging. An important advantage of the invention is the use of a larger x-ray generation area on the anode for a given x-ray spot size, which allows higher electrical power to be delivered to the anode than is possible with prior art sources. Another important advantage is the use of more of the electron beam to generate x-rays and reduce the inefficiency of prior art sources. A further advantage is the adaptability of the invention in source ranging from single channel sources to highly parallel array sources of x-rays. The ability to make large arrays of x-ray flux beams in linear, 2D and curved formats enables new imaging modalities not possible with prior art sources. The x-ray source of this system can be scaled to very large arrays of hundreds or thousands of x-ray flux beams.
This invention provides a source of x-ray flux in which x-rays are produced by e-beams impacting the inner walls of holes or channels formed in a metal anode such that most of the electrons reaching the channel impact an upper portion of said channel. A portion of the electrons from this primary impact will generate x-rays. Most of the electrons scatter but they continue to ricochet down the channel, most of them generating x-rays, until the beam is spent. A single channel source of high power efficiency and high power level x-rays may be made in this way, or the source can be of an array of such channels, to produce parallel collimated flux beams of x-rays.
The attached drawings are provided to help describe the structure, operation, and some embodiments of the source of the present invention. Numerous other designs, methods of operation and applications are within the meaning and scope of the invention.
Although the following detailed description delineates specific attributes of the invention and describes specific designs and fabrication procedures, those skilled in the arts of radiographic imaging or radiation source production will realize that many variations and alterations in the fabrication details and the basic structures are possible without departing from the generality of the processes and structures.
The FFC x-ray source comprises at least a cathode and a metal anode with at least one hole (termed a channel) through the anode such that x-rays may be produced by e-beams accelerated by an electrical potential between cathode and anode to impact the upper portion of the inner wall of the channel, which may also be called the upper acceptance region. The channel will typically be annular, but other channel shapes may also be used. A small portion of the electrons (estimated at under 25%) will produce x-rays from this primary impact but most of the electrons will be scattered, mostly in the forward direction of the e-beam trajectory, with the scattered electrons again impacting the walls of the channel and either generating x-rays or scattering again, the scattered electrons then repeating the process until most of the electron beam has generated x-rays. The electrons lose slight amounts of their energy after each ricochet off the walls, but not enough to effect the amount and quality of the x-ray flux. A portion of the x-rays generated at the inner channel walls will transmit through the channel. The x-ray flux beam profile is determined by the shape of the metal channel, which serves as a collimator. If the channel has straighter walls the x-ray flux beam will have a narrow angle, and can be a straight pencil beam. If the channel flares outward towards its end, the x-ray flux beam angel will increase. FFC sources can be designed and made to produce x-ray flux beam shapes intended for various purposes.
The FFC source can be open or sealed and single channel or multi-channel. Open sources, such as are used in some microfocus x-ray imaging and analytical instruments, are actively pumped, so the x-ray source does not need its own permanently sealed vacuum package, and the vacuum chamber of the open source may include other parts of an imaging system or instrument. Sealed sources are made to be vacuum tight and are evacuated once all the elements of the source are installed and the package is sealed, typically through a pump-down tube, although in vacuo sealing methods may also be used. Flash or non-evaporable getters may be used to maintain the vacuum in sealed sources.
The source can be operated at any of the voltages used in current medical and industrial imaging settings, as well as in scientific instruments and in irradiation applications, i.e. from under 1 kV to 250 kV. Even higher voltages may be used in FFC sources intended for radiation therapy and similar applications, provided that sufficient distance is made between the cathode and anode to avoid high voltage breakdown and the electron beam is confined, for example through electrostatic means or magnetic means.
The current levels in single or multi-channel FFC sources will also depend on the application, but in general much higher current levels can be used compared to prior art sources, due to the ability of a larger anode impact area to dissipate instantaneous heat, which can decrease image acquisition times and provide other advantages in x-ray instruments. In prior art reflective or transmissive x-ray sources the spot size is given by the diameter of the anode target impacted by the e-beam and the available electron impact area is πr2 (or πr2 times about 4 in the case of an angled reflective target). In the disclosed source, the spot size is given by the diameter of the channel, but the available electron impact area is provided by the surface of the inner wall of the channel, or hnd, where h is the height of the channel (thickness of the anode) and d is the diameter of the spot. With a 100 μm spot and 2 mm thick plate, for example, this works out to 80 times the surface area. In practice, only a part of the channel height, mostly to about the first 500 μm, will generate x-rays, which is still a 20× increase in surface area and a profound increase in the power capacity of the anode spot. For a 20 μm spot this increase is 100×. These increases translate directly to higher feasible current levels. With the 20 μm spot size, for example, even with a 4× geometrical leverage, an FFC source will be able to handle 25 times the power of a stationary x-ray tube with an angled anode target, a profound advantage in many applications.
A small portion of the e-beam entering the FFC source will not generate x-rays at the channel walls through either primary or secondary (scattered) impact. This portion can impact a thin film of metal disposed across the diameter of the end of the channel, where it will either generate more x-rays or be drained away. The x-rays generated at the channel walls, and those few generated at the exit of the channel exit the channel to the other side of the cathode. In a sealed source, the anode window provided at the end of the channel may support the thin metal. In an open source a simple drain electrode located near the channel end may also be used.
In some FFC configurations, particularly those with a small anode thickness/channel height, a further electrode may be provided near the flux exit end of the channel. This electrode may be used to attract electrons into the channel and help direct current into the channel walls.
Virtually all the x-rays generated by the FFC source are from Bremsstrahlung or characteristic line radiation. The power efficiency of the FFC source is determined by several parameters, including the anode material and accelerating voltage, the size (height and diameter) and shape of the channel, particularly any flare out of the channel at the end, and the number of times the electron beam impacts the channel wall, which may be five to ten in channels several mm in height. Compared to prior art sources, FFC sources will lose some efficiency because the collimation of the channel constrains the x-ray flux getting through. When this is made normal through comparison with similarly collimated other sources, the FFC shows gains in efficiency due to the use of more of the e-beam and the hardening of the x-ray flux as lower energy x-rays are more likely to be absorbed by the channel walls. The inventors have analyzed these efficiency gains using models generated with the Monte Carlo PENELOPE particle code developed at Oak Ridge National Labs. The models include all aspects of electron trajectories, scattering and x-ray generation inside the channels, and x-ray flux generation through the channels. Graphical output from these models is included in
Various channel shapes and electron beam acceptance angles can be used in FFC sources.
The channels in FFC sources may be fabricated a number of ways in a number of anode metals, such as W, Mo, Cu or Au. The metals may be chosen for the desired x-ray generation characteristics for a given anode voltage and ease of fabrication. In sealed sources, the metal may be chosen for ease of fabrication and thermal compatibility (such as with Kovar) with the rest of the vacuum package materials set, and another metal, chosen for its x-ray characteristics plated, evaporated, sputtered or otherwise deposited on the inner channel walls. For larger diameter channels, down to about 100 μm, diamond drilling and water jet can be used. For smaller channels the fabrication process choices include plunge EDM, laser milling, molding, chemical etch and focused ion beams (FIB). FIB tools are reliable for small feature sizes and can be programmed for complex shapes. They also have micro/nano etch capabilities. Another choice, for example with the hourglass-shaped channels, is to micro-mill halves of the shape on Cu or Kovar strips and then braze them together. A molding process is a further option. Arrays of silicon pillars in the desired shape can be formed with various processes then Cu plated, deposited or melted around them; the Si is then etched away.
There are also a number of cathode choices, including cold cathode field emitters, thermal filament emitters, dispenser cathodes or any other cathode which will fit into the source. Exemplary cold cathodes, particularly for cathode arrays, lateral thin film edge emitters, which may be made of various, materials, including carbon, layered films of different forms of carbon, carbon nanotubes or graphene, layered films of metal, layered films of metal and carbon, etc. Cathodes in the array may be stabilized by the incorporation of resistors for individual emitters of areas. The cathodes in the array may also be gated, so as to allow operation of the cathodes at lower voltages. Gates and focusing elements, such as electrostatic lenses, may be provided so as to direct the e-beams in an optimal direction. An exemplary cold cathode for an array is a disk pusher cathode, in which a large number of individual cold cathode tips face in towards a circular pusher electrode, which defines the spot size of the e-beam and which directs the electrons up off the cathode substrate and towards the anode. The pusher electrode may be biased so as to focus the beam and this focusing may be used in conjunction with other focusing elements. The beam shape is annular. Another cold cathode choice, for very tight annular beams, is to deposit large numbers of thin films of alternative insulating and conductive/emissive materials, such as diamond and Mo, around very thin wires, which are rotated in the deposition chamber. The wires are then into small sections to provide an annular metal-insulator-metal cold cathode which has proven to yield high, stable current levels. Another method for producing an annular beam, detailed below, is to use an internal accelerating grid with a retarding potential at the lower levels of the stack to widen the beam just before impact on the upper acceptance region of the anode channel.
A sealed, single channel FFC x-ray source is shown in
An FFC array source, shown in
The FFC arrays may be made in a number of formats and sizes. Cathode and channel pitch, their number, their arrangement and channel width and height may be chosen to suit the application.
The cathode array can be operated in a variety of modes to generate x-ray pixels (xels) from the anode channels in whatever format suits the application. Xels may be address sequentially, maybe be multiplexed, may all be turned on at once, may be scanned as lines, or may be addressed in coded source patterns. For example, in an exemplary parallel beam imaging mode, a 77×77 array of xels will substantially reduce scatter in the imaging subject, allowing for the same image quality to be obtained at substantially lower doses. All the axels are operated simultaneously in this mode. With a large number of xels it is also possible to modulate the cathodes in the cathode array so as to provide spatial variations in the generated x-ray flux pattern. This may be used in dose reduction regimes which rely on lessening the dose in regions of less interest in the imaging application.
FFC array sources generating pencil beams or narrowly collimated beams of x-ray flux may also be advantageously used in PCI systems. Some PCI approaches can use polychromatic x-ray sources, for example, grating-based Talbot interferometry. In these approaches, the FFC source of
The present invention is well adapted to carry out the objects and attain the ends and advantages described as well as others inherent therein. While the present embodiments of the invention have been given for the purpose of disclosure numerous changes or alterations in the details of construction and steps of the method will be apparent to those skilled in the art and which are encompassed within the spirit and scope of the invention.
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