Fragrance Fixatives and Compositions Comprising Thereof

Abstract
The present invention relates to substantially non-odorous fragrance fixatives for extending the fragrance intensity or character, of fragrance materials over time. The invention also covers compositions of fragrance materials and the substantially non-odorous fragrance fixatives and methods of use of the compositions for perfuming suitable substrates, including hard surfaces and body parts, particularly skin and hair.
Description
FIELD OF THE INVENTION

The present invention concerns substantially non-odorous fragrance fixatives and compositions comprising said substantially non-odorous fragrance fixatives to extend the fragrance profile, preferably the fragrance intensity and/or fragrance character, of the fragrance materials over time.


BACKGROUND OF THE INVENTION

Fragrances in some products, particularly (but not exclusively) ethanol-based ones, tend to lose their fragrance profile (i.e., character and intensity) rapidly after application. Various materials have been used to make the fragrance profile last longer. These are known as fragrance fixatives. Some substantially non-odorous examples include: (i) capsules or complexes based on dextrines, melamines or obtained by coacervation of anionic and cationic polymers, (ii) film-forming polymers, or (iii) perfume base notes such as musks. The drawbacks of capsules or complexes are that they are difficult to formulate into a fragrance composition and/or the release is little controlled but depends on variable factors like moisture or sebum amount or sweat intensity. The issue with film-forming polymers is that they produce very noticeable and undesirable films (both visual and tactile). The disadvantage of perfume base notes is that they can negatively impact the fragrance character of the compositions to which they are added.


Thus, there is a need for new fragrance fixatives to extend the fragrance profile, preferably the intensity or character, of a fragrance material to maintain its intensity over time and particularly in retaining the initial character and intensity of the characters. It is also desirable that the fragrance fixatives should not adversely affect the aromatic and/or aesthetic character of the products to which they are added.


SUMMARY OF THE INVENTION

In one aspect, the present invention provides a substantially non-odorous fragrance fixative comprising at least one material selected from the group consisting of the materials in Table 1, as provided herein below.


In another aspect, the present invention is directed to a composition comprising a fragrance component present in an amount of from about 0.04 wt % to about 30 wt %, relative to the total weight of the composition, and at least one substantially non-odorous fragrance fixative, as described herein below, present in an amount of from about 0.1 wt % to about 20 wt %, relative to the total weight of the composition.


In yet another aspect, the present invention is further directed to a method of modifying or enhancing the odour properties of a surface with a composition of the present invention, by contacting or treating the surface with the composition.


In yet another aspect, the present invention is further directed to a composition comprising fragrance materials and a substantially non-odorous fragrance fixative according to Table 1 for extending the fragrance profile of the fragrance materials vs. a control composition absent of the substantially non-odorous fragrance fixative.


These and other features of the present invention will become apparent to one skilled in the art upon review of the following detailed description when taken in conjunction with the appended claims.





BRIEF DESCRIPTION OF THE DRAWINGS

While the specification concludes with claims particularly pointing out and distinctly claiming the invention, it is believed that the invention will be better understood from the following description of the accompanying figures wherein:



FIG. 1 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition A comprising Dimethyl Benzyl Carbinol fragrance material and Piperonyl butoxide substantially non-odorous fragrance fixative as compared to Composition B, a control absent of a substantially non-odorous fragrance fixative (Piperonyl butoxide), and as a function of time elapsed since application of the composition.



FIG. 2 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensityof Composition C comprising Eugenol fragrance material and Piperonyl butoxide substantially non-odorous fragrance fixative as compared to Composition D, a control absent of a substantially non-odorous fragrance fixative (Piperonyl butoxide), and as a function of time elapsed since application of the composition.



FIG. 3 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition I comprising Dimethyl Benzyl Carbinol fragrance material and Poly(PG)monobutyl ether substantially non-odorous fragrance fixative as compared to Composition J, a control absent of a substantially non-odorous fragrance fixative (Poly(PG)monobutyl ether), and as a function of time elapsed since application of the composition.



FIG. 4 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition K comprising Eugenol fragrance material and Poly(PG)monobutyl ether substantially non-odorous fragrance fixative as compared to Composition L, a control absent of a substantially non-odorous fragrance fixative (Poly(PG)monobutyl ether), and as a function of time elapsed since application of the composition.



FIG. 5 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition M comprising Phenethyl alcohol (PEA) fragrance material and Poly(PG)monobutyl ether substantially non-odorous fragrance fixative as compared to Composition N, a control absent of a substantially non-odorous fragrance fixative (Poly(PG)monobutyl ether), and as a function of time elapsed since application of the composition.



FIG. 6 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition Q comprising Indole fragrance material and Triglycol substantially non-odorous fragrance fixative as compared to Composition R, a control absent of a substantially non-odorous fragrance fixative (Triglycol), and as a function of time elapsed since application of the composition.



FIG. 7 provides the panel test results of perceived fragrance profile, particularly improved fragrance intensity of Composition S comprising Eugenol fragrance material and Triglycol substantially non-odorous fragrance fixative as compared to Composition T, a control absent of a substantially non-odorous fragrance fixative (Triglycol), and as a function of time elapsed since application of the composition.



FIG. 8 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD1) comprising a volatile fragrance material mixture and Tergitol® 15-S-7 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 9 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD2) comprising a volatile fragrance material mixture and PPG-7-Buteth-10 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 10 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD3) comprising a volatile fragrance material mixture and Nikkol PBC-33 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 11 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD4) comprising a volatile fragrance material mixture and Neodol 45-7 Alcohol Ethoxylate substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 12 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD5) comprising a volatile fragrance material mixture and Bio-soft N25-7 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 13 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD6) comprising a volatile fragrance material mixture and Bio-soft N23-6.5 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 14 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD7) comprising a volatile fragrance material mixture and Cremophor® A 25 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 15 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MODE) comprising a volatile fragrance material mixture and Bio-soft N91-8 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 16 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD9) comprising a volatile fragrance material mixture and Genapol® C-100 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 17 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD10) comprising a volatile fragrance material mixture and Rhodasurf® LA 30 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 18 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD11) comprising a volatile fragrance material mixture and Poly(ethylene glycol) methyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 19 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD12) comprising a volatile fragrance material mixture and Arlamol™ PS11E substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 20 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD13) comprising a volatile fragrance material mixture and Brij® S100 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 21 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD14) comprising a volatile fragrance material mixture and Brij® C-58 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 22 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD15) comprising a volatile fragrance material mixture and Pluronic® F-127 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 23 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD16) comprising a volatile fragrance material mixture and Bio-soft N1-5 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 24 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD17) comprising a volatile fragrance material mixture and Polyoxyethylene (10) lauryl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 25 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD18) comprising a volatile fragrance material mixture and Arlamol™ PC10 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 26 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD19) comprising a volatile fragrance material mixture and Poly(ethylene glycol) (18) tridecyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 27 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD20) comprising a volatile fragrance material mixture and ALFONIC® 10-8 Ethoxylate substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 28 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD21) comprising a volatile fragrance material mixture and Brij® 020-SS substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 29 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD22) comprising a volatile fragrance material mixture and Diethylene glycol butyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 30 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD23) comprising a volatile fragrance material mixture and Ethylene glycol monohexadecyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 31 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD24) comprising a volatile fragrance material mixture and Poly(propylene glycol) monobutyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 32 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD25) comprising a volatile fragrance material mixture and Dowanol™ TPnB substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 33 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD26) comprising a volatile fragrance material mixture and Tripropylene Glycol substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 34 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD27) comprising a volatile fragrance material mixture and Cithrol™ substantially non-odorous fragrance fixative as compared to a control composition (REF27), and as a function of time elapsed since application of the composition.



FIG. 35 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD28) comprising a volatile fragrance material mixture and Igepal® CO-630 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 36 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD29) comprising a volatile fragrance material mixture and Nikkol Decaglyn 3-OV substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 37 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD30) comprising a volatile fragrance material mixture and NIKKOL Hexaglyn 1-L substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 38 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD31) comprising a volatile fragrance material mixture and Emalex CS-10 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 39 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD32) comprising a volatile fragrance material mixture and Dioctyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 40 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD33) comprising a volatile fragrance material mixture and Jeecol CA-10 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 41 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD34) comprising a volatile fragrance material mixture and Steareth-10 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 42 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD35) comprising a volatile fragrance material mixture and Nonaethylene glycol monododecyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 43 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD36) comprising a volatile fragrance material mixture and Glycerol propoxylate substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 44 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD37) comprising a volatile fragrance material mixture and Glycerol ethoxylate substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 45 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD38) comprising a volatile fragrance material mixture and Hexaethylene glycol monohexadecyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 46 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD39) comprising a volatile fragrance material mixture and Aquaflex™ XL-30 substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 47 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD40) comprising a volatile fragrance material mixture and Piperonyl Butoxide substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 48 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD41) comprising a volatile fragrance material mixture and Diphenhydramine HCl substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 49 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD42) comprising a volatile fragrance material mixture and Di(propylene glycol) propyl ether substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.



FIG. 50 provides the evaporation profile results for a representative component (i.e., indole) of test composition (MOD43) comprising a volatile fragrance material mixture and Poly(melamine-co-formaldehyde) methylated substantially non-odorous fragrance fixative as compared to a control composition (REF), and as a function of time elapsed since application of the composition.





DETAILED DESCRIPTION OF THE INVENTION
Definitions

As used herein, articles such as “a” and “an” when used in a claim, are understood to mean one or more of what is claimed or described.


As used herein, the terms “include”, “includes” and “including” are meant to be non-limiting.


As used herein, the term “body splash” means a body care formulation that is applied to the body. Typically, the body splash is applied to the body after bathing and provides a subtle hint of scent to the body. Body splashes are commonly used by consumers who prefer less strong fragrance compositions. A body splash may comprise an ethanol-free composition according to the present invention which comprises from 0.2-8 wt %, relative to the total weight of the composition, of a fragrance component. The body splash may further comprise alkyl polyglucosides as non-ionic surfactants.


As used herein, the term “body spray” means a formulation comprising fragrance materials intended to be applied to the body to prevent or mask body odor caused by the bacterial breakdown of perspiration on the body (e.g., armpits, feet, and other areas of the body). The body spray may also provide a fragrance expression to the consumers. Typically, body spray compositions are applied as an aerosol spray in an effective amount on the skin of a consumer.


As used herein, the term “composition” includes a fine fragrance composition intended for application to a surface, such as for example, body surface like skin or hair, i.e., to impart a pleasant odour thereto, or cover a malodour thereof. They are generally in the form of perfume concentrates, perfumes, parfums, eau de parfums, eau de toilettes, aftershaves, or colognes. The fine fragrance compositions may be an ethanol-based composition. The term “composition” may also include a cosmetic composition, which comprises a fragrance material for the purposes of delivering a pleasant smell to drive consumer acceptance of the cosmetic composition. The term “composition” may also include body splashes or body sprays. The term “composition” may also include cleaning compositions, such as fabric care composition or home care compositions, including air care compositions (e.g., air fresheners), for use on clothing or other substrates such as hard surfaces (e.g., dishes, floors, countertops). Additional non-limiting examples of “composition” may also include facial or body powder, foundation, deodorant, body/facial oil, mousse, creams (e.g., cold creams), waxes, sunscreens and blocks, bath and shower gels, lip balms, self-tanning compositions, masks and patches.


As used herein, the term “consumer” means both the user of the composition and the observer nearby or around the user.


As used herein, the terms “fragrance” and “perfume” are used interchangeably to designate the component in the composition that is formed of fragrance materials, i.e., ingredients capable of imparting or modifying the odour of skin or hair or other substrate.


As used herein, the term “fragrance material” and “fragrance materials” relates to a perfume raw material, or a mixture of perfume raw materials, that are used to impart an overall pleasant odour or fragrance profile to a composition. “Fragrance materials” can encompass any suitable perfume raw materials for fragrance uses, including materials such as, for example, alcohols, aldehydes, ketones, esters, ethers, acetates, nitriles, terpene hydrocarbons, nitrogenous or sulfurous heterocyclic compounds and essential oils. However, naturally occurring plant and animal oils and exudates comprising complex mixtures of various chemical components are also know for use as “fragrance materials”. The individual perfume raw materials which comprise a known natural oil can be found by reference to Journals commonly used by those skilled in the art such as “Perfume and Flavourist” or “Journal of Essential Oil Research”, or listed in reference texts such as the book by S. Arctander, Perfume and Flavor Chemicals, 1969, Montclair, N.J., USA and more recently re-published by Allured Publishing Corporation Illinois (1994). Additionally, some perfume raw materials are supplied by the fragrance houses (Firmenich, International Flavors & Fragrances, Givaudan, Symrise) as mixtures in the form of proprietary speciality accords. Non-limiting examples of the fragrance materials useful herein include pro-fragrances such as acetal pro-fragrances, ketal pro-fragrances, ester pro-fragrances, hydrolyzable inorganic-organic pro-fragrances, and mixtures thereof. The fragrance materials may be released from the pro-fragrances in a number of ways. For example, the fragrance may be released as a result of simple hydrolysis, or by a shift in an equilibrium reaction, or by a pH-change, or by enzymatic release.


As used herein, the term “fragrance profile” means the description of how the fragrance is perceived by the human nose at any moment in time. The fragrance profile may change over time. It is a result of the combination of the low volatile fragrance materials and the volatile fragrance materials, if present, of a fragrance. A fragrance profile is composed of 2 characteristics: ‘intensity’ and ‘character’. The ‘intensity’ relates to the perceived strength whilst ‘character’ refers to the odour impression or quality of the perfume, i.e., fruity, floral, woody, etc.


As used herein, the terms “fixative” and “fragrance fixative” are used interchangeably to designate an agent having the capacity to affect the fragrance profile, such as for example, by impacting the fragrance materials' evaporation rate. The fixative may mediate its effect by lowering the vapor pressure of the fragrance materials and increasing their adherence to the substrate (skin and/or hair) thus ensuring a longer-lasting impression of the fragrance. Suitable examples of the fixative are provided herein below, particularly in Table 1.


As used herein, the term “substantially non-odorous” means an agent that does not impart an odour of its own when added into a composition of the present invention. For example, a “substantially non-odorous fragrance fixative” does not impart a new odour that alters the character of the fragrance profile of the composition to which it is added. The term “substantially non-odorous” also encompasses an agent that may impart a minimal or slight odour of its own when added into a composition of the present invention. However, the odour imparted by the “substantially non-odorous fragrance fixative” is generally undetectable or tends to not substantively alter the character of the fragrance profile of the composition to which it is added initially or preferably over time. Furthermore, the term “substantially non-odorous” also includes materials that are perceivable only by a minority of people or those materials deemed anosmic to the majority of people. Furthermore, the term “substantially non-odorous” also includes materials that may, from particular suppliers, contain an odour due to impurities, such as when the materials contain the impurities at not more than about 5 wt %, preferably not more than 1 wt %, often even not more than 1 part per million (ppm). These impurities maybe removed by purification techniques known in the art as required to make them suitable for use in fragrance compositions of the present invention.


As used herein, the term “vapor pressure” means the partial pressure in air at a defined temperature (e.g., 25° C.) and standard atmospheric pressure (e.g., 760 mmHg or 101.325 kPa) for a given chemical species. It defines a chemical species' desire to be in the gas phase rather than the liquid or solid state. The higher the vapor pressure the greater the proportion of the material that will, at equilibrium, be found in a closed headspace. It is also related to the rate of evaporation of a fragrance material which is defined in an open environment where material is leaving the system. The vapor pressure is determined according to the reference program Advanced Chemistry Development (ACD/Labs) Software Version 14.02, or preferably the latest version update).


It is understood that the test methods that are disclosed in the Test Methods Section of the present application must be used to determine the respective values of the parameters of Applicants' inventions as described and claimed herein.


In all embodiments of the present invention, all percentages are by weight of the total composition, as evident by the context, unless specifically stated otherwise. All ratios are weight ratios, unless specifically stated otherwise, and all measurements are made at 25° C., unless otherwise designated.


Substantially Non-Odorous Fragrance Fixatives The inventors have discovered new agents that can be used as substantially non-odorous fragrance fixatives, as described herein below, to enhance or improve the fragrance profile, preferably the intensity or character, of the fragrance material. Preferable examples of the substantially non-odorous fragrance fixatives are provided in Table 1 below.


Preferably, the substantially non-odorous fragrance fixative is present in an amount of from about 0.1 wt % to about 20 wt %, preferably from about 0.5 wt % to about 18 wt % or more preferably from about 2.5 wt % to about 15 wt % or combinations thereof, relative to the total weight of the composition. Alternatively, the substantially non-odorous fragrance fixative is present in an amount of from about 0.1 wt %, 0.5 wt % or 2.5 wt % to about 15 wt %, 18 wt % or 20 wt %, relative to the total weight of the composition. If there is more than one substantially non-odorous fragrance fixatives, then the ranges provided hereinabove cover the total of all of the substantially non-odorous fragrance fixatives.


The substantially non-odorous fragrance fixatives of the present invention may be a liquid at temperatures lower than 100° C., preferably at ambient temperature. The substantially non-odorous fragrance fixatives may be fully miscible with the fragrance materials to form a single phase liquid. However, if the fragrance materials are not entirely miscible, or are immiscible, then co-solvents (e.g., dipropylene glycol (DPG), triethyl citrate, or others as well known to those skilled in the art) can be added to aid in the solubility of the fragrance materials.


Preferably, the composition according to the present invention, wherein the substantially non-odorous fragrance fixatives and fragrance component are present in a weight ratio from about 10:1 to about 1:10, preferably from about 5:1 to about 1:5, or preferably from about 3:1 to about 1:3.


The inventors have discovered that the substantially non-odorous fragrance fixatives can extend the fragrance intensity of the fragrance material over time, preferably over long periods of time such as for example, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 10 hours, and possibly all the way up to 24 hrs after application as compared to controls, i.e., compositions containing no substantially non-odorous fragrance fixatives.


Additionally, the inventors have discovered that the substantially non-odorous fragrance fixatives can extend the fragrance character, preferably the portion of the fragrance profile attributable to the volatile fragrance materials. By “extend” it is meant that the fragrance profile of the composition, preferably the components contributed by the volatile fragrance materials, can be pereceived by the consumer at later time points such as for example, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 10 hours, and possibly all the way up to 24 hrs after application as compared to controls, i.e., compositions containing no substantially non-odorous fragrance fixatives.


Compositions

In one aspect, the present invention provides for a composition comprising a fragrance component present in an amount of from about 0.04 wt % to 30 wt %, preferably 1 wt % to about 30 wt %, more preferably less than about 25 wt %, yet more preferably less than about 20 wt %, yet even more preferably less than about 15 wt %, yet even more preferably less than about 10 wt % or most preferably less than about 8 wt %, relative to the total weight of the composition. Alternatively, the fragrance component is present in an amount of from about 0.04 wt %, 0.3 wt %, 1 wt %, 2 wt %, 5 wt %, 8 wt % or 10 wt %, to about 15 wt %, 20 wt %, 25 wt % or 30 wt %, relative to the total weight of the composition.


Preferably, the compositions of the present invention comprise:

    • (i) a fragrance component present in an amount of from about 0.04 wt % to about 30 wt %, relative to the total weight of the composition; and
    • (ii) at least one substantially non-odorous fragrance fixative from the group consisting of the materials in Table 1, wherein the substantially non-odorous fragrance fixative is present in the amount of from about 0.1 wt % to about 20 wt %, relative to the total weight of the composition.


Preferably, the composition of the present invention, wherein:

    • (i) fragrance component is present preferably from about 0.04 wt %, 0.1 wt %, 0.5 wt %, 1 wt % or 2 wt % to about 30 wt %, 25 wt %, 20 wt %, 15 wt %, 10 wt % or 8 wt %, relative to the total weight of the composition, and wherein the fragrance component comprises:
      • (a) at least one low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25° C.; and
      • (b) the low volatile fragrance material is present in an amount of less than about 30 wt %, or less than about 28 wt %, or less than about 25 wt %, relative to the total weight of the fragrance component; and
    • (ii) at least one substantially non-odorous fragrance fixative present in the amount of preferably from about 0.1 wt % to about 20 wt %, or preferably from about 0.5 wt % to about 18 wt %, or more preferably from about 2.5 wt % to about 15 wt %, relative to the total weight of the composition.


Preferably, the composition of the present invention, wherein the low volatile fragrance material is present in an amount of from about 10 wt % to about 30 wt %, relative to the total weight of the fragrance component.


Preferably, the present invention relates to a fine fragrance composition, preferably in the form of of a perfume concentrate, a perfume, a parfum, an eau de toilette, an eau de parfum, or a cologne.


Preferably, the present invention relates to a composition, wherein the composition is in the form of a body splash or a body spray.


Therefore, it goes without saying that the compositions of the present invention encompasses any composition comprising any of the ingredients cited herein, in any embodiment wherein each such ingredient is independently present in any appropriate amount as defined herein. Many such compositions, than what is specifically set out herein, can be encompassed.


Entrapment Materials

In yet another aspect, compositions of the present invention may comprise an entrapment material at a level such that the weight ratio of the entrapment material to the fragrance materials is in the range of from about 1:20 to about 20:1. Preferably, the composition may comprise an entrapment material present in the amount of from about 0.001 wt % to about 40 wt %, from about 0.1 wt % to about 25 wt %, from about 0.3 wt % to about 20 wt %, from about 0.5 wt % to about 10 wt %, or from about 0.75 wt % to about 5 wt %, relative to the total weight of the composition. The compositions disclosed herein may comprise from 0.001 wt % to 40%, from 0.1 wt % to 25 wt %, from 0.3 wt % to 20 wt %, from 0.5 wt % to 10 wt % or from 0.75 wt % to 5 wt %, relative to the total weight of the composition, of a cyclic oligosaccharide.


Suitable entrapment materials for use herein are selected from polymers; capsules, microcapsules and nanocapsules; liposomes, absorbents; cyclic oligosaccharides and mixtures thereof. Preferred are absorbents and cyclic oligosaccharides and mixtures thereof. Highly preferred are cyclic oligosaccharides (see PCT Publication Nos. WO2000/67721 (Procter & Gamble); and WO2000/67720 (Procter & Gamble); and U.S. Pat. No. 6,893,647 (Procter & Gamble)).


Volatile Solvents

In yet another aspect, the present invention provides the solution to the problem of extending the longevity of the fragrance profile of compositions, particularly fine fragrance and cosmetic compositions, preferably fine fragrance compositions, which commonly contain high levels of a volatile solvent. Preferably, the composition according to the present invention, further comprising a volatile solvent present in the amount of from about 10 wt %, 20 wt %, 30 wt %, 40 wt % or 50 wt % to about 90 wt %, 80 wt %, 70 wt % or 60 wt %, relative to the total weight of the composition, and wherein the solvent is a branch or unbranched C1 to C10 alkyl, akenyl or alkynyl having at least one alcohol moiety, preferably ethanol, or isopropanol, or other alcohols (e.g., methanol, propanol, isopropanol, butanol, and mixtures thereof) commonly found in commercial fine fragrance products.


Accordingly, ethanol may be present in any of the compositions of the present invention, and more specifically, it will form from about 10 wt % to about 80 wt %, or even from about 25 wt % to about 75 wt % of the composition, or combinations thereof, relative to the total weight of the composition. Alternatively, ethanol may be present in an amount of from about 10 wt % or 25 wt % to about 75 wt % or 80 wt %, relative to the total weight of the composition. The ethanol useful in the present invention may be any acceptable quality of ethanol, compatible and safe for the specific intended use of the composition such as, for example, topical applications of fine fragrance or cosmetic compositions.


Non-Volatile Solvents

The composition may comprise a non-volatile solvent or a mixture of non-volatile solvents. Non-limiting examples of non-volatile solvents include benzyl benzoate, diethyl phthalate, isopropyl myristate, propylene glycol, dipropylene glycol, triethyl citrate, and mixtures thereof. These solvents often are introduced to the product via the perfume oil as many perfume raw materials may be purchased as a dilution in one of these solvents. Where non-volatile solvents are present, introduced either with the perfume materials or separately, then for the purposes of calculating the proportion of fragrance component having a vapor pressure of less than 0.001 Torr (0.000133 kPa) at 25° C. the total fragrance components does not include non-volatile solvents. Where non-volatile solvents are present, introduced either with the perfume materials or separately, then for the purposes of calculating the total level of fragrance component this does not include non-volatile solvents. In addition if present with cyclic oligosacchrides, the non-volatile solvent may be included at a weight ratio of the non-volatile solvent to the cyclic oligosaccharide of less than 1:1, less than 1:2, less than 1:10, or less than 1:100.


Water

In yet another aspect, water may be present in any of the compositions of the present invention, and more specifically, it shall not exceed about 40 wt %, preferably about 20 wt % or less, or more preferably about 10 wt % or less, relative to the total weight of the composition. Alternatively, water may be present in an amount of from about 10 wt % or about 20 wt % to about 40 wt %, relative to the total weight of the composition. When the composition is a cosmetic composition the level of water should not be so high that the product becomes cloudy thus negatively impacting the product aesthetics. It is understood that the amount of water present in the composition may be from the water present in the volatile solvent (e.g., ethanol) used in the composition, as the case may be.


Propellants

The compositions described herein may include a propellant. Some examples of propellants include compressed air, nitrogen, inert gases, carbon dioxide, and mixtures thereof. Propellants may also include gaseous hydrocarbons like propane, n-butane, isobutene, cyclopropane, and mixtures thereof. Halogenated hydrocarbons like 1,1-difluoroethane may also be used as propellants. Some non-limiting examples of propellants include 1,1,1,2,2-pentafluoroethane, 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3-heptafluoropropane, trans-1,3,3,3-tetrafluoroprop-1-ene, dimethyl ether, dichlorodifluoromethane (propellant 12), 1,1-dichloro-1,1,2,2-tetrafluoroethane (propellant 114), 1-chloro-1,1-difluoro-2,2-trifluoroethane (propellant 115), 1-chloro-1,1-difluoroethylene (propellant 142B), 1,1-difluoroethane (propellant 152A), monochlorodifluoromethane, and mixtures thereof. Some other propellants suitable for use include, but are not limited to, A-46 (a mixture of isobutane, butane and propane), A-31 (isobutane), A-17 (n-butane), A-108 (propane), AP70 (a mixture of propane, isobutane and n-butane), AP40 (a mixture of propane, isobutene and n-butane), AP30 (a mixture of propane, isobutane and n-butane), and 152A (1,1 diflouroethane). The propellant may have a concentration from about 15%, 25%, 30%, 32%, 34%, 35%, 36%, 38%, 40%, or 42% to about 70%, 65%, 60%, 54%, 52%, 50%, 48%, 46%, 44%, or 42% by weight of the total fill of materials stored within the container.


Antiperspirant Active

The compositions described herein may be free of, substantially free of, or may include an antiperspirant active (i.e., any substance, mixture, or other material having antiperspirant activity). Examples of antiperspirant actives include astringent metallic salts, like the inorganic and organic salts of aluminum, zirconium and zinc, as well as mixtures thereof. Such antiperspirant actives include, for example, the aluminum and zirconium salts, such as aluminum halides, aluminum hydroxyhalides, zirconyl oxyhalides, zirconyl hydroxyhalides, and mixtures thereof.


Other Ingredients

In yet another aspect, the composition consists essentially of the recited ingredients but may contain small amounts (not more than about 10 wt %, preferably no more than 5 wt %, or preferably no more than 2 wt % thereof, relative to the total weight of the composition) of other ingredients that do not impact on the fragrance profile, particularly the evaporation rate and release of the fragrance materials. For example, a fine fragrance composition may comprise stabilizing or anti-oxidant agents, UV filters or quenchers, or colouring agents, commonly used in perfumery.


In yet another aspect, the composition of the present invention, depending on its intended use, is a mixture of fragrance materials possibly together with other ingredients such as, for example, perfume carriers. By the term “perfume carrier”, it is meant to include materials which are practically neutral from a perfumery point of view, i.e., which does not significantly alter the organoleptic properties of perfuming components. The perfume carrier may be a compatible liquid or solid fillers, diluents, and the like. The term “compatible”, as used herein, means that the components of the compositions of this invention are capable of being combined with the primary actives of the present invention, and with each other, in a manner such that there is no interaction which would substantially reduce the efficacy of the composition under ordinary use situations. The type of carrier utilized in the present invention depends on the type of product desired and may comprise, but are not limited to, solutions, aerosols, emulsions (including oil-in-water or water-in-oil), gels, and liposomes. Preferably, the carrier is a liquid and will be a solvent such as, for example, dipropyleneglycol, diethyl phthalate, isopropyl myristate, benzyl benzoate, 2-(2-ethoxyethoxy)-1-ethanol, or ethyl citrate (triethyl citrate).


In yet another aspect, the compositions for use in the present invention may take any form suitable for use, more preferably for perfumery or cosmetic use. These include, but are not limited to, vapor sprays, aerosols, emulsions, lotions, liquids, creams, gels, sticks, ointments, pastes, mousses, powders, granular products, substrates, cosmetics (e.g., semi-solid or liquid makeup, including foundations) and the like. Preferably the compositions for use in the present invention take the form of a vapor spray. Compositions of the present invention can be further added as an ingredient to other compositions, preferably fine fragrance or cosmetic compositions, in which they are compatible. As such they can be used within solid composition or applied substrates etc.


Article of Manufacture

The composition may be included in an article of manufacture comprising a spray dispenser. The spray dispenser may comprise a vessel for containing the composition to be dispensed. The spray dispenser may comprise an aerosolized composition (i.e. a composition comprising a propellant) within the vessel as well. Other non-limiting examples of spray dispensers include non-aerosol dispensers (e.g. vapor sprays), manually activated dispensers, pump-spray dispensers, or any other suitable spray dispenser available in the art.


Methods of Using the Compositions

The composition of the present invention according to any embodiments described herein is a useful perfuming composition, which can be advantageously used as consumer products intended to perfume any suitable substrate or surface. As used herein, the term “substrate” means any surface to which the composition of the present invention may be applied to without causing any undue adverse effect. For example, this can include a wide range of surfaces including human or animal skin or hair, paper (fragranced paper), air in a room (air freshener or aromatherapy composition), fabric, furnishings, dishes, hard surfaces and related materials. Preferred substrates include body surfaces such as, for example, hair and skin, most preferably skin.


The composition of the present invention may be used in a conventional manner for fragrancing a substrate. An effective amount of the composition, typically from about 1 μL to about 10,000 μL, preferably from about 10 μL to about 1,000 μL, more preferably from about 25 μL to about 500 μL, or most preferably from about 50 μL to about 100 μL, or combinations thereof, is applied to the suitable substrate. Alternatively, an effective amount of the composition of the present invention is from about 1 μL, 10 μL, 25 μL or 50 μL to about 100 μL, 500 μL, 1,000 μL or 10,000 μL. The composition may be applied by hand or applied utilizing a delivery apparatus such as, for example, vaporizer or atomizer. Preferably, the composition is allowed to dry after its application to the substrate. The scope of the present invention should be considered to cover one or more distinct applications of the composition or the continuous release of a composition via a vaporizer or other type of atomizer.


The present invention provides a method of modifying or enhancing the odour properties of a body surface, preferably hair or skin, comprising contacting or treating the body surface with a composition of the present invention.


The present invention also relates to compositions of the present invention that may be used as consumer products or articles selected from the group consisting of a fabric care product, an air care product, or a home care product. Therefore, according to this embodiment, the present invention provides a method of modifying or enhancing the odour properties of a substrate, preferably fabric, furnishings, dishes, hard surfaces and related materials, comprising contacting or treating the substrate with a composition of the present invention.


In another aspect, the present invention is directed to a method of enhancing the fragrance profile of a composition, preferably by improving the longevity of a character of the composition. The method comprises bringing into contact or mixing at least one substantially non-odorous fragrance fixative with the fragrance material according to the composition of the present invention. Preferably, the character is derived from the volatile fragrance materials in the composition and is characterized by a floral character or aromatic/spicy character. Non-limiting examples of floral character include: lavender-type note, a rose-type note, a lily of the valley-type note, a muguet-type note, a jasmine-type note, a magnolia-type note, a cyclamen-type note, a hyacinth-type note, a lilac-type note, an orange blossom-type note, a cherry blossom-type note, a peony-type note, a lotus-type note, a linden blossom-type note, an osmanthus-type note, a heliotrope-type note, a violet-type note, an orris-type note, a tiare-type, a patchouli-type note and the like.


Non-limiting examples of aromatic (or haerbaceous) and spicy character include: cinnamon, cloves, coriander, ginger, saffron, peppers of various kinds (e.g.: black pepper, pink pepper), caraway, cardamom, anise, tea, coffee, cumin, nutmeg, coumarin, basil, rosemary, thyme, mint, tarragon, marjoram, fennel, sage, and juniper.


Preferably, the fragrance profile or character of the composition of the present invention is detectable by a consumer at later time points such as, for example, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 10 hours, and possibly all the way up to 24 hours after application of the composition to a substrate as compared to controls.


In another aspect, the present invention is also directed to a method of producing a consumer product comprising bringing into contact or mixing into the product an organoleptically active quantity of a composition of the present invention. Preferably, the present invention is also directed to a perfuming consumer product or article comprising a composition according to the present invention, wherein the perfuming consumer product is selected from the group consisting of a fabric care product, an air care product or a home care product.


Substantially Non-Odorous Fragrance Fixatives

In one aspect, compositions of the present invention comprise at least one substantially non-odorous fixative selected from the group consisting of the materials disclosed in Table 1.









TABLE 1







Substantially Non-Odorous Fragrance Fixatives














CAS



No.
Chemical or INCI Name
Trade Name
Number
Supplier














1.
C12-14 Sec-Pareth-3
Tergitol ® 15-S-7
68131-
Sigma Aldrich





40-8
(UK)


2.
Poly(ethylene glycol-ran-
PPG-7-Buteth-10
9038-
Sigma Aldrich



propylene glycol) monobutyl

95-3
(UK)



ether





3.
PPG-4-Ceteth-10
Nikkol PBC-33
37311-
Chemical Navi





01-6



4.
Deceth-4
Ethal DA-4
5703-
Ethox





94-6
Chemicals,






Inc.


5.
PPG-5-Ceteth-20
AEC PPG-5-Ceteth-20
9087-
A & E





53-0
Connock






(Perfumery &






Cosmetics)






Ltd.


6.
C14-15 Pareth-7
Neodol 45-7 alcohol
68951-
Shell




ethoxylate
67-7
Chemical






Company


7.
Linear alcohol (C12-15)
Bio-soft N25-7
68131-
Stephan



Pareth-3ethoxylate, POE-7

39-5
Company


8.
Linear alcohol (C12-13)
Bio-soft N23-6.5
66455-
(USA)



Pareth-3ethoxylated, POE-6.5)

14-9



9.
Polyethylene glycol 1100
Cremophor ® A 25
68439-
Sigma Aldrich



mono(hexadecyl/octadecyl)

49-6
(UK)



ether





10.
Linear alcohol (C9-11)
Bio-soft N91-8
68439-
Stephan



ethoxylated POE-8 Pareth-3

46-3
Company (USA)


11.
Coceth-10 or Polyoxyethylene
Genapol ® C-100
61791-13-7
Sigma Aldrich (UK)



(10) dodecyl ether





12.
Alcohols, C12-14, ethoxylated
Rhodasurf ® LA 30
68439-50-9
Solvay






Solutions Italia S.p.A


13.
Poly(ethylene glycol)
Poly(ethylene glycol)
9004-74-4
Sigma Aldrich (UK)



methyl ether
methyl ether




14.
C10-16 Pareth-1
Neodol ® PC 110
68002-97-1
Shell Chemical






Company


15.
PPG-11 Stearyl Ether Kj
Arlamol ™ PS11E
25231-21-4
Croda (UK)


16.
Steareth-100
Brij ® S100
9005-00-9
Sigma Aldrich (UK)


17.
Polyethylene glycol
Brij ® C-58
9004-95-9
Sigma Aldrich (UK)



hexadecyl ether





18.
Pluronic ® F-127
Pluronic ® F-127
9003-11-6
Sigma Aldrich (UK)


19.
Linear Alcohol (C11)
Bio-soft N1-5
34398-01-1
Stepan Canada Inc.



Elhoxylate, POE-5





20.
Laureth-10
Intrasol FA 12/18/10
6540-99-4
Evonik Industries AG


21.
Decaethylene glycol
Polyoxyethylene (10)
9002-92-0
Sigma Aldrich (UK)



mono-dodecyl ether
lauryl ether




22.
Ethylene glycol
2-Methoxyethanol
109-86-4
Sigma Aldrich (UK)



monomethyl ether





23.
Myreth-4
Homulgator 920 G
27306-79-2
Grau Aromatics






GmbH & Company KG


24.
Oleth-16 Alkoxylated Alcohols
Pegnol O-16A
25190-05-0
Toho Chemical






Industry Co., Ltd.


25.
Isosteareth-5
Emalex 1805
52292-17-8
Nihon Emulsion






Company, Ltd.


26.
PPG-10 Cetyl Ether
Arlamol ™ PC 10
9035-85-2
Croda (UK)


27.
Polyoxy(ethylene glycol)
Poly(ethylene glycol)
24938-91-8
Sigma-Aldrich (UK)



(18) tridecyl ether
(18) tridecyl ether




28.
Poly(oxy-1,2-ethanediyl),
ALFONIC ® 10-8
26183-52-8
Sasol Chemicals



a-decyl-w-hydroxy-
Ethoxylate

(USA) LLC


29.
Laureth-1
Mackam ™ 2LSF
4536-30-5
Rhodia (DE)


30.
PEG-5 Hydrogenated
Ethox HTAM-5
61791-26-2
Ethox Chemicals, Inc.



Tallow Amine





31.
PEG-15 Oleamine
Nikkol TAMNO-15
26635-93-8
Nikko Chemicals






Co., Ltd.


32.
Polyoxyethylene (20) oleyl ether
Brij ® O20-SS
9004-98-2
Sigma Aldrich (UK)


33.
Cetoleth-10
Brij ® CO10
8065-81-4
Croda, Inc.


34.
Talloweth-7
Emulmin 70
61791-28-4
Sanyo Chemical






Industries Ltd.


35.
Isobutoxypropanol Alcohols
Isobutoxypropanol
34150-35-1
MolPort


36.
Isobutoxypropanol Alcohols
Isobutoxypropanol
23436-19-3
AKos Consulting &






Solutions


37.
Dielhylene Glycol
Twincide EDG
111-46-6
Roda


38.
Methoxyethanol
Hisolve MC
109-86-4
Toho Chemical






Industry Co., Ltd.


39.
Ethoxyethanol Alcohols
2-Ethoxyethanol
110-80-5
Sigma-Aldrich (UK)


40.
Methoxyisopropanol Alcohols
Dowanol ™ PM
107-98-2
The Dow Chemical






Company


41.
Methoxyethanol
Hisolve MC
32718-54-0
Toho Chemical






Industry Co., Ltd.


42.
Methylal Ethers
Dimethoxymelhane
109-87-5
Sigma-Aldrich (UK)


43.
3-Methoxybutanol
Methoxybutanol
2517-43-3
Hans Schwarzkopf






GmbH/Co. KG


44.
Butoxyethanol
Butyl OXITOL
111-76-2
Shell Chemical






Company


45.
Propylene Glycol n-Butyl Ether
Dowanol ™ PnB
5131-66-8/
The Dow Chemical





29387-86-8
Company


46.
Propylene Glycol Butyl Ether
Propylene Glycol Butyl Ether
15821-83-7
Sigma Aldrich (UK)


47.
2-(2-butoxyethoxy)ethanol
Diethylene glycol butyl ether
112-34-5
Sigma Aldrich (UK)


48.
Deceth-4 Phosphate
Crodafos ™ D4A
52019-36-0
Croda, Inc.


49.
2-(Hexadecyloxy)ethanol
Ethylene glycol
2136-71-2
Sigma-Aldrich (UK)




monohexadecyl ether




50.
Poly(propylene glycol)
Poly(propylene glycol)
9003-13-8
Sigma-Aldrich (UK)



monobutyl ether
monobutyl ether




51.
Propylene Glycol Propyl Ether
Dowanol ™ PnP
30136-13-1
The Dow Chemical






Company


52.
Propylene Glycol n-Butyl Ether
Dowanol ™ PnB
29387-86-8/
The Dow Chemical





5131-66-8
Company


53.
Dipropylene glycol
Di(propylene glycol) methyl
34590-94-8
Sigma Aldrich (UK)



monomethyl ether
ether, mixture of isomers




54.
Dipropylene Glycol
Proglyde ™ DMM
111109-77-4
The Dow Chemical



Dimethyl Ether


Company


55.
PPG-2 Methyl Ether
Dowanol ™ DPM
13429-07-7
The Dow Chemical






Company


56.
Methoxydiglycol Ethers
OriStar DEGME
111-77-3
Orient Stars LLC


57.
Diethylene glycol ethyl ether
Di(ethylene glycol) ethyl ether
111-90-0
Sigma Aldrich (UK)


58.
Dimethoxydiglycol Ethers
Dimethyldiglycol
111-96-
H&V Chemicals


59.
PPG-3 Methyl Ether
Dowanol ™ TPM
37286-64-9
The Dow Chemical






Company


60.
Methyl Morpholine
224286 ALDRICH
7529-22-8
Sigma-Aldrich (UK)



Oxide Amine Oxides
4-Methylmorpholine N-oxide




61.
Oleth-3
Brij ® O3
5274-66-8
Croda Europe, Ltd.


62.
Tri(propylene glycol)
Dowanol ™ TPnB
55934-93-5
Sigma-Aldrich (UK)



n-butyl ether





63.
Tripropylene Glycol
Tripropylene Glycol
24800-44-0
Sigma-Aldrich (UK)


64.
PPG-3 Methyl Ether
Dowanol ™ TPM
25498-
The Dow



Alkoxylaled Alcohols

49-1
Chemical Company


65.
Triethylene glycol
Triglycol
112-27-6
Sigma Aldrich (UK)


66.
PEG-3 Methyl Ether
Hymol ™
112-35-6
Toho Chemical






Industry Co., Ltd.


67.
Laureth-3
AEC Laureth-3
3055-94-5
A & E Connock






(Perfumery &






Cosmetics) Ltd.


68.
Ethylhexylglycerin
AG-G-75008
70445-33-9
Angene Chemical


69.
Tetra(ethylene glycol)
Tetraethylene glycol
112-60-7
Sigma Aldrich (UK)


70.
Steareth-3
Isoxal 5
4439-32-1
Vevy Europe SpA


71.
Ceteth-3
Emalex 103
4484-59-7
Nihon Emulsion






Company, Ltd.


72.
Myreth-3
Isoxal 5
26826-30-2
Vevy Europe SpA


73.
Trideceth-3
Alfonic ® TDA-

Sasol North America.




3 Ethoxylate

Inc.


74.
Ceteth-2
Brij ® C2
5274-61-3
Croda Europe, Ltd.


75.
Oleth-2
Brij ® O2
5274-65-7
Croda, Inc.


76.
Steareth-2
Brij ® S2
16057-43-5
Croda, Inc.


77.
Cetoleth-10
Brij ® CO10
8065-81-4
Croda, Inc.


78.
Trimethyl Pentanol
Trimethyl Pentanol
68959-25-1
Angene Chemical



Hydroxyethyl Ether Alcohols
Hydroxyethyl Ether




79.
Steareth-10 Allyl Ether
Salcare ® SC80
109292-17-3
BASF


80.
TEA-Lauryl Ether
material ID-AG-J-99109
1733-93-3
Angene Chemical


81.
Polyglyceryl-2 Oleyl Ether
Chimexane NB
71032-90-1
Chimex


82.
Batyl Alcohol
B402 ALDRICH
544-62-7
Sigma-Aldrich (UK)


83.
Octaethylene Glycol
15879 ALDRICH
5117-19-1
Sigma-Aldrich (UK)


84.
Triglycerol diisostearate
Cithrol ™
66082-42-6
Croda (UK)


85.
Diglycerin
Diglycerin 801
59113-36-9
Sakamoto Yakuhin






Kogyo Co., Ltd.


86.
Polyglycerin #310
Polyglycerin #310
25618-55-7
Sakamoto Yakuhin






Kogyo Co., Ltd.


87.
Distearyl Ether
Cosmacol ® SE
6297-03-6
Sasol Germany GmbH


88.
Caprylyl Glyceryl Ether
Caprylyl Glyceryl Ether
10438-94-5
AKos Consulting &






Solutions


89.
Chimyl Alcohol
Chimyl Alcohol
506-03-6
Nikko Chemicals






Co., Ltd.


90.
Dipentaerythrityl
Liponate ® DPC-6
68130-24-5
Lipo Chemicals, Inc.



Hexacaprylate/Hexacaprate





91.
Morpholine
394467 ALDRICH
110-91-8
Sigma-Aldrich (UK)


92.
Dimethyl Oxazolidine
OXABAN ™-A
51200-87-4
The Dow Chemical






Company


93.
Ethyl Hydroxymethyl
4-Oxazolemethanol
68140-98-7
Angene Chemical



Oleyl Oxazoline





94.
Methyl Hydroxymethyl
Adeka Nol GE-RF
14408-42-5
Adeka Corporation



Oleyl Oxazoline





95.
Pramoxine HCl
OriStar PMHCL
637-58-1
Orient Stars LLC


96.
Allantoin Ascorbate
Allantoin Ascorbate
57448-83-6
ABI Chem


97.
Stearamidopropyl
Mackalene ™ 326
55852-14-7
Rhodia Inc.



Morpholine Lactate





98.
Dioxolane
Elcotal DX
646-06-0
Lambiotte & CIE S.A.


99.
Glycerol Formal
Glycerol Formal
5464-28-8
Sigma Aldrich (UK)


100.
Stearamidopropyl Morpholine
Mackine 321
55852-13-6
Rhodia Inc.


101.
2,4,6-Tris[bis(methoxymethyl)
Poly(melamine-co-
68002-20-0
Sigma-Aldrich (UK)



amino]-1,3,5-triazine
formaldehyde)methylated




102.
Poloxamine 1307
Pluracare ® 1307
11111-34-5
BASF


103.
Nonoxynol-8
Igepal ® CO-610
27177-05-5
Rhodia Inc.


104.
Nonoxynol-10
Igepal ® CO-710
27177-
Rhodia Inc.





08-8



105.
Octoxynol-10
Nikkol OP-10
2315-66-4
Nikko Chemicals






Co., Ltd.


106.
Nonoxynol-9
Igepal ® CO-630
68987-90-6
Rhodia Inc.


107.
Nonoxynol-9 Iodine
Nonoxynol-9 iodine
94349-40-3
Angene Chemical


108.
Octylphenoxy
Igepal ® CA-630
68987-90-6
Rhodia Inc.



poly(ethyleneoxy)ethanol,






branched





109.
Sodium Octoxynol-2
Triton™ X-200
55837-16-6
The Dow Chemical



Ethane Sulfonate


Company


110.
Benzylhemiformal
Preventol D2
14548-60-8
Lanxess Corporation


111.
Nonoxynol-2
Igepal ® CO-210
27176-93-8
Rhodia Inc.


112.
Octoxynol-3
Igepal ® CA-420
2315-62-0
The Dow Chemical






Company


113.
Nonoxynol-3
Marlophen NP 3
27176-95-0
Sasol Germany GmbH


114.
Alkoxylaled Alcohols
Alkasurf NP-4
7311-27-5
Rhodia Inc.


115.
Nonoxynol-3
Triethylene Glycol
51437-95-7
Santa Cmz




Mono(p-nonylphenyl)Ether

Biotechnology


116.
Nonoxynol-7
Lowenol 2689
27177-03-3
Jos. H. Lowenstein






& Sons, Inc.


117.
Nonoxynol-6
Igepal ® CO-530
27177-01-1
Rhodia Inc.


118.
Nonoxynol-5
Igepal ® CO-520
20636-48-0
Rhodia Inc.


119.
Nonoxynol-5
Igepal ® CO-520
26264-02-8
Rhodia Inc.


120.
Nonoxynol-4
Alkasurf NP-4
27176-97-2
Rhodia Inc.


121.
Polyglyceryl-10 Trioleate
Nikkol Decaglyn 3-OV
102051-00-3
Nikko Chemicals






Co., Ltd.


122.
Polyglyceryl-10 Dioleate
Nikkol Decaglyn 2-O
33940-99-7
Nikko Chemicals






Co., Ltd


123.
Polyglyceryl-10 Tetraoleale
Caprol 10G40
34424-98-1
Abitec Corporation


124.
Polyglyceryl-10 Stearate
Nikkol Decaglyn 1-SV
79777-
Nikko




EX
30-3
Chemicals Co., Ltd.


125.
Polyglyceryl-10 Oleate
S-Face O-1001 P
79665-93-3
Sakamoto Yakuhin






Kogyo Co., Ltd.


126.
Polyglyceryl-10 Myristale
Nikkol Decaglyn 1-MV EX
87390-32-7
Nikko Chemicals






Co., Ltd.


127.
Dermofeel® G 10 L
Dermofeel ® G 10 L
34406-66-1
Dr. Straetnians


128.
Polyglyceryl-6 Laurate
NIKKOL Hexaglyn 1-L
51033-38-6
Chemical Navi


129.
Polyglyceryl-6 Isostearate
S-Face IS-601 P
126928-07-2
Sakamoto Yakuhin






Kogyo Co., Ltd.


130.
Choleth-10
Emalex CS-10
27321-96-6
Nihon Emulsion






Company, Ltd.


131.
Steareth-10 Allyl
Salcare ® SC80
109292-17-3
BASF



Ether/Acrylates Copolymer





132.
Polyvinyl Stearyl Ether
Giovarez ® 1800
9003-90-7
Phoenix Chemical, Inc.


133.
Dicetyl Ether
Cosmacol Ether 16

Sasol Germany GmbH


134.
PPG-23-Steareth-34
Unisafe 34S-23
9038-43-1
Pola Chemical






Industries, Inc.


135.
Stearoxypropyl
Farmin DM E-80
17517-01-0
Kao Corp.



Dimethylamine





136.
Dislearyl Ether
Cosmacol SE
6297-03-6
Sasol Germany GmbH


137.
Polyquaternium-10
AEC Polyquaternium-10
55353-19-0
A & E Connock






(Perfumery &






Cosmetics) Ltd.


138.
Octyl ether
Dioctyl ether
629-82-3
Sigma Adlrich (UK)


139.
Ethyl Ether
Diethyl Ether
60-29-7
EMD Chemicals


140.
Methyl Hexyl Ether Ethers
methyl hexyl ether
4747-07-3
TCI AMERICA


141.
Ceteth-12
Emalex 112
94159-75-8
Nihon Emulsion






Company, Ltd.


142.
Ceteth-10 or cetyl
Jeecol CA-10
14529-
Jeen



alcohol POE-10

40-9
International


143.
Steareth-10
Jeecol SA-10
13149-86-5
Jeen International


144.
Nonaethylene glycol
Nonaethylene glycol
3055-99-0
Sigma Aldrich (UK)



monododecyl ether
monododecyl ether




145.
Oleth-10
Brij ® O10
71976-00-6
Croda, Inc.


146.
Oleth-10
Brij ® O10
24871-34-9
Croda, Inc.


147.
PEG-12
Carbowax ™ PEG 600
6790-09-6
The Dow Chemical






Company


148.
PEG-9
Sabopeg 400
3386-18-3
Sabo s.p.a.


149.
PEG-10
DECAETHYLENE
5579-66-8
MolPort




GLYCOL




150.
PEG-6
Carbowax ™ PEG 300
2615-15-8
The Dow Chemical






Company


151.
Glycerol propoxylate
Glycerol propoxylate
25791-96-2
Sigma Aldrich (UK)


152.
Glycerol ethoxylate
Glycerol ethoxylate
31694-55-0
Sigma Aldrich (UK)


153.
Laureth-8
AEC Laureth-8
3055-98-9
A & E Con nock






(Perfumery &






Cosmetics) Ltd.


154.
Oleth-8
Emalex 508
27040-03-5
Nihon Emulsion






Company, Ltd.


155.
Laureth-7
Alfonic 1216CO-7
3055-97-8
Sasol North




Ethoxylate

America, Inc.


156.
Steareth-7
Polyoxyethylene (7)
66146-84-7
Sigma Aldrich




stearyl ether




157.
Deceth-6
Alfonic 1012-6.0 Ethoxylate
5168-89-8
Sasol North






America, Inc.


158.
Steareth-6
Emalex 606
2420-29-3
Nihon Emulsion






Company, Ltd.


159.
Hexaethylene
Hexaethylene glycol
3055-96-7
Sigma-Aldrich (UK)



glycol monododecyl ether
monododecyl ether




160.
Hexaethylene glycol
Hexaethylene glycol
5168-91-2
Sigma-Aldrich (UK)



monohexadecyl ether
monohexadecyl ether




161.
Beheneth-5
Nikkol BB-5
136207-49-3
Nikko Chemicals






Co., Ltd.


162.
Myreth-5
Isoxal 12
92669-01-7
Vevy Europe SpA


163.
Steareth-5
Jeecol SA-5
71093-13-5
Jeen International






Corporation


164.
Ceteth-5
Emalex 105
4478-97-1
Nihon Emulsion






Company, Ltd.


165.
Oleth-5
Brij ® O5
5353-27-5
Croda, Inc.


166.
Laureth-5
Safol ® 23E5 Ethoxylate
3055-95-6
Sasol North






America, Inc.


167.
Steareth-4
Jeecol SA-4
59970-10-4
Jeen International






Corporation


168.
Laureth-4
Brij ® L4
5274-68-0
Croda, Inc.


169.
Myreth-4
Homulgator 920 G
39034-24-7
Grau Aromatics GmbH






& Company KG


170.
Ceteth-4
Procol CA-4
5274-63-5
Protameen Chemicals


171.
Oleth-4
Chemal OA-4
5353-26-4
Chemax, Inc.


172.
Oleth-4
Chemal OA-4
103622-85-1
Chemax, Inc.


173.
Polyimide-1
Aquaflex ™ XL-30
497926-97-3
Chemwill


174.
Polymethoxy Bicyclic
Caswell No. 494CA
56709-13-8
Angene Chemical



Oxazolidine





175.
Hydroxymethyl
Zoldine ™ ZT
6542-37-6
Angus Chemical



Dioxoazabicyclooctane


Company


176.
Dihydro-7a-ethyloxazolo
5-Ethyl-1-aza-3,7-
7747-35-5
Sigma Aldrich (UK)



[3,4-c]oxazole
dioxabicyclo[3.3.0]octane




177.
Dibenzylidene Sorbitol
Disorbene ®
32647-67-9
Roquette America, Inc.


178.
Dimethyldibenzylidene
Millad ® 3988
135861-56-2
Milliken Chemicals



Sorbitol





179.
Laureth-2
Alfonic 1216CO-2
3055-93-4
Sasol North




Ethoxylate

America, Inc.


180.
2-(2-Butoxyethoxy)ethyl
Piperonyl Butoxide
51-03-6
Sigma-Aldrich (UK)



(6-propylpiperonyl) ether





181.
Menthone Glycerin Acetal
Frescolat ® MGA
63187-91-7
Symrise


182.
Propylene Glycol Caprylate
Mackaderm PGC
68332-79-6
Rhodia Inc.


183.
Diethoxynonadiene
SBB016951
67674-36-6
Ambi liter


184.
Menthoxypropanediol
Coolact ® 10
87061-04-9
Takasago



Alcohols


International






Corporation


185.
2-Diphenylmethoxy-N,N-
Diphenhydramine HCl
147-24-0
Sigma-Aldrich (UK)



dimethylethylamine






hydrochloride





186.
3-((2-ethylhexyl)oxy)

70445-33-9




propane-1,2-diol





187.
3-((2-propylheptyl)oxy)






propane-1,2-diol





188.
1-amino-3-((2-ethylhexyl)oxy)

99509-00-9




propan-2-ol





189.
1-(1-Methyl-2-
Di(propylene glycol)
29911-27-1
Sigma Aldrich (UK)



propoxyelhoxy)-2-propanol
propyl ether




190.
propyl {4-[2-(diethylamino)-2-
Kolliphor ® EL
61791-12-6
Sigma Aldrich (US)



oxoethoxy]-3-methoxyphenyl)






acetate





191.
Bis-methoxy PEG-13
Expert Gel ® EG56
936645-35-1
PolymerExpert S.A.



PEG-438/PPG-110 SMDI


(Pessac, France)



Copolymer









The compounds selected from the group consisting of Table 1 substantially non-odorous fragrance fixatives 1-190, 191, and mixtures thereof, act as a substantially non-odorous fragrance fixative of the present invention. For example, the substantially non-odorous fragrance fixatives, with a fragrance component act to prolong the duration during which the fragrance profile, preferably the characters attributable from the volatile fragrance materials, can be perceived as compared to a control composition in the absence of the fixatives. As another example, the substantially non-odorous fragrance fixatives with a fragrance component, can improve the fidelity of the fragrance profile, preferably the fragrance component derived from the volatile fragrance materials, such that it remains significantly the same from initial impression to the end as compared to a control composition in the absence of the substantially non-odorous fragrance fixatives. While not wishing to be bound by theory, it is believed that the substantially non-odorous fragrance fixatives associate to the fragrance materials and retard evaporation. This may be due to a combination of both the functionality and the structure of the substantially non-odorous fragrance fixatives and the fragrance materials.


Fragrance Materials

Preferably, the “fragrance materials” have been classified as low volatile fragrance materials or volatile fragrance materials by their vapor pressure. For the purpose of clarity, when the fragrance materials refer to a single individual compound, its vapor pressure should be determined according to the reference program cited above. In the case that the fragrance materials are a natural oil, extract or absolute, which comprises a mixture of several compounds, the vapor pressure of the complete oil should be treated a mixture of the individual perfume raw material components using the reference program cited above. The individual components and their level, in any given natural oil or extract, can be determined by direct injection of the oil into a GC-MS column for analysis as known by one skilled in the art. In the scenario that the fragrance materials are a proprietary specialty accord, so called ‘bases’, the vapor pressure, using the reference program cited above, should preferably be obtained from the supplier. However, it is understood by one skilled in the art that they can physically analyze the composition of a full fragrance oil available commercially to identity the fragrance raw materials and their levels using standard GC-MS techniques. This would be irrespective of whether they had been added to the fragrance oil as individual chemicals, as components of naturals or from proprietary bases. Although proprietary bases and naturals are included in our examples, when analyzing a commercially available fragrance via GC-MS one could simply identify the components of the base or natural oil as part of the overall fragrance mixture and their levels, without being able to identify which proprietary base or natural oil the fragrance had come from.


The nature and type of fragrance materials in the compositions according to the present invention can be selected by the skilled person, on the basis of its general knowledge together with the teachings contained herein, with reference to the intended use or application of the composition and the desired fragrance profile effect. Examples of suitable fragrance materials are disclosed in U.S. Pat. No. 4,145,184, U.S. Pat. No. 4,209,417, U.S. Pat. No. 4,515,705, and U.S. Pat. No. 4,152,272.


(i) Low Volatile Fragrance Materials


Fragrance materials classified as “low volatile fragrance materials” are ones having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25° C. Preferably, the low volatile fragrance materials form the at most about 30 wt %, wherein the wt % is relative to the total weight of the fragrance component. Preferably, the low volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials, or at least 5 materials, or at least 7 materials as disclosed in Table 2.









TABLE 2







Low Volatile Fragrance Materials












CAS


Vapor Pressure


No.
Number
IUPAC Name
Common Name**
(Torr at 25° C.)*














1.
1211-29-6
Cyclopentaneacetic acid, 3-oxo-2-
Methyl jasmonate
0.00096500




(2Z)-2-penten-1-yl-, methyl ester,






(1R,2R)-




2.
28219-60-5
2-Buten-1-ol, 2-methyl-4-
Hindinol
0.00096100




(2,2,3-trimethyl-3-cyclopenten-1-yl)-




3.
93-08-3
Ethanone, 1-(2-naphthalenyl)-
Methyl beta-
0.00095700





naphthyl ketone



4.
67633-95-8
3-Decanone, 1-hydroxy-
Methyl Lavender
0.00095100





Ketone



5.
198404-98-7
Cyclopropanemethanol, 1-methyl-2-
Javanol ®
0.00090200




[(1,2,2-trimethylbicyclo[3.1.0]






hex-3-yl)methyl]-




6.
121-32-4
Benzaldehyde, 3-ethoxy-4-hydroxy-
Ethyl vanillin
0.00088400


7.
72403-67-9
3-Cyclohexene-1-methanol, 4-
Myraldylacetate
0.00087900




(4-methyl-3-penten-1-yl)-, 1-acetate




8.
28940-11-6
2H-1,5-Benzodioxepin-3(4H)-
Calone
0.00083100




one, 7-methyl-




9.
139504-68-0
2-Butanol, 1-[[2-(1,1-dimethylethyl)
Amber core
0.00080300




cyclohexyl)oxy]-




10.
502847-01-0
Spiro[5.5]undec-8-en-1-one, 2,2,7,
Spiro[5.5]undec-
0.00073100




9-tetramethyl-
8-en-1-one, 2,2,7,






9-tetramethyl-



11.
2570-03-8
Cyclopentaneacetic acid, 3-oxo-2-pentyl-,
trans-Hedione
0.00071000




methyl ester, (1R,2R)-rel-




12.
24851-98-7
Cyclopentaneacetic acid, 3-oxo-2-pentyl-,
Methyl
0.00071000



(or 128087-96-7)
methyl ester
dihydrojasmonate






or alternatives 1



13.
101-86-0
Octanal, 2-(phenylmethylene)-
Hexyl
0.00069700





cinnamic aldehyde



14.
365411-50-3
Indeno[4,5-d]-1,3-dioxin,
Nebulone
0.00069200




4,4a,5,6,7,8,9,9b-octahydro-7,7,8,9,9-






pentamethyl-




15.
37172-53-5
Cyclopentanecarboxylic acid,
Dihydro Iso
0.00067500




2-hexyl-3-oxo-, methyl ester
Jasmonate



16.
65113-99-7
3-Cyclopentene-1-butanol,
Sandalore ®
0.00062500




α,β,2,2,3-pentamethyl-




17.
68133-79-9
Cyclopentanone, 2-(3,7-
Apritone
0.00062000




dimethyl-2,6-octadien-1-yl)-




18.
7212-44-4
1,6,10-Dodecatrien-3-ol, 3,7,11-
Nerolidol
0.00061600




trimethyl-




19.
53243-59-7
2-Pentenenitrile, 3-methyl-5-
Citronitril
0.00061500




phenyl-, (2Z)-




20.
134123-93-6
Benzenepropanenitrile,
Fleuranil
0.00057600




4-ethyl-α,α-dimethyl-




21.
77-53-2
1H-3a,7-Methanoazulen-6-ol,
Cedrol Crude
0.00056900




octahydro-3,6,8,8-tetramethyl-,






(3R,3aS,6R,7R,8aS)-




22.
68155-66-8
Ethanone, 1-(1,2,3,5,6,7,8,8a-
Iso Gamma Super
0.00056500




octahydro-2,3,8,8-tetramethyl-2-






naphthalenyl)-




23.
54464-57-2
Ethanone, 1-(1,2,3,4,5,6,7,8-
Iso-E Super ®
0.00053800




tetramethyl-2-naphthalenyl)-




24.
774-55-0
Ethanone, 1-(5,6,7,8-tetrahydro-
Florantone
0.00053000




2-naphthalenyl)-




25.
141-92-4
2-Octanol, 8,8-dimethoxy-2,6-dimethyl-
Hydroxycitronellal
0.00052000





Dimethyl Acetal



26.
20665-85-4
Propanoic acid, 2-methyl-,
Vanillin
0.00051200




4-formyl-2-methoxyphenyl ester
isobutyrate



27.
79-78-7
1,6-Heptadien-3-one,
Hexalon
0.00049800




1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-




28.
6259-76-3
Benzoic acid, 2-hydroxy-, hexyl ester
Hexyl Salicylate
0.00049100


29.
93-99-2
Benzoic acid, phenyl ester
Phenyl Benzoate
0.00047900


30.
153859-23-5
Cyclohexanepropanol, 2,2,6-
Norlimbanol
0.00046900




trimethyl-α-propyl-, (1R,6S)-




31.
70788-30-6
Cyclohexanepropanol, 2,2,6-
Timberol
0.00046900




trimethyl-α-propyl-




32.
68555-58-8
Benzoic acid, 2-hydroxy-,
Prenyl Salicylate
0.00045700




3-methyl-2-buten-1-yl ester




33.
950919-28-5
2H-1,5-Benzodioxepin-3(4H)-
Cascalone
0.00045500




one, 7-(1-methylethyl)-




34.
30168-23-1
Butanal, 4-(octahydro-4,7-methano-
Dupical
0.00044100




5H-inden-5-ylidene)-




35.
1222-05-5
Cyclopenta[g]-2-benzopyran,
Galaxolide ®
0.00041400




1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-






hexamethyl-




36.
4602-84-0
2,6,10-Dodecatrien-1-ol, 3,7,11-
Farnesol
0.00037000




trimethyl-




37.
95962-14-4
Cyclopentanone, 2-[2-(4-methyl-
Nectaryl
0.00036700




3-cyclohexen-1-yl)propyl]-




38.
4674-50-4
2(3H)-Naphthalenone, 4,4a,5,6,7,8-
Nootkatone
0.00035800




hexahydro-4,4a-dimethyl-6-(1-






methylethenyl)-, (4R,4aS,6R)-




39.
3487-99-8
2-Propenoic acid, 3-phenyl-, pentyl ester
Amyl Cinnamate
0.00035200


40.
10522-41-5
2-hydroxy-2-phenylethy acetate
hydroxyphenethyl
0.00033900





acetate



41.
118-71-8
4H-Pyran-4-one, 3-hydroxy-2-methyl-
Maltol
0.00033700


42.
128119-70-0
1-Propanol, 2-methyl-3-[(1,7,7-
Bornafix
0.00033400




trimethylbicyclo[2.2.1]hept-2-yl) oxy]-




43.
103614-86-4
1-Naphthalenol, 1,2,3,4,4a,5,8,8a-
Octalynol
0.00033200




octahydro-2,2,6,8-tetramethyl-




44.
7785-33-3
2-Butenoic acid, 2-methyl-, (2E)-
Geranyl Tiglate
0.00033200




3,7-dimethyl-2,6-octadien-1-yl ester, (2E)-




45.
117933-89-8
1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-
Karanal
0.00033100




1-yl)-5-methyl-5-(1-methylpropyl)-




46.
629-92-5
Nonadecane
Nonadecane
0.00032500


47.
67801-20-1
4-Penten-2-ol, 3-methyl-5-(2,2,3-
Ebanol
0.00028100




trimethyl-3-cyclopenten-1-yl)-




48.
65416-14-0
Propanoic acid, 2-methyl-, 2-methyl-4-
Maltol
0.00028000




oxo-4H-pyran-3-yl ester
Isobutyrate



49.
28219-61-6
2-Buten-1-ol, 2-ethyl-4-(2,2,3-trimethyl-
Laevo
0.00028000




3-cyclopenten-1-yl)-
Trisandol



50.
5986-55-0
1,6-Methanonaphthalen-1(2H)-ol, octahydro-
Healingwood
0.00027800




4,8a,9,9-tetramethyl-, (1R,4S,4aS,6R,8aS)-




51.
195251-91-3
2H-1,5-Benzodioxepin-3(4H)-one,
Transluzone
0.00026500




7-(1,1-dimethylethyl)-




52.
3100-36-5
8-Cyclohexadecen-1-one
Cyclohexadecenone
0.00025300


53.
65405-77-8
Benzoic acid, 2-hydroxy-, (3Z)-3-
cis-3-Hexenyl
0.00024600




hexen-1-yl ester
salicylate



54.
4940-11-8
4H-Pyran-4-one, 2-ethyl-3-hydroxy-
Ethyl Maltol
0.00022800


55.
541-91-3
Cyclopentadecanone, 3-methyl-
Muskone
0.00017600


56.
118-58-1
Benzoic acid, 2-hydroxy-,
Benzyl
0.00017500




phenylmethyl ester
salicylate



57.
81783-01-9
6,8-Nonadien-3-one, 2,4,4,7-
Labienoxime
0.00017300




tetramethyl-, oxime




58.
25485-88-5
Benzoic acid, 2-hydroxy-,
Cyclohexyl
0.00017300




cyclohexyl ester
Salicylate



59.
91-87-2
Benzene, [2-(dimethoxymethyl)-
Amyl Cinnamic
0.00016300




1-hepten-1-yl]-
Aldehyde Dimethyl






Acetal



60.
104864-90-6
3-Cyclopentene-1-butanol,
Firsantol
0.00016000




(β,2,2,3-tetramethyl-δ-methylene-




61.
224031-70-3
4-Penten-1-one, 1-spiro[4.5]dec-7-
Spirogalbanone
0.00015300




en-7-yl-




62.
134-28-1
5-Azulenemethanol, 1,2,3,4,5,6,7,8-
Guaiyl Acclaic
0.00013400




ociahydro-α,α,3,8-tetramethyl-, 5-






acetate, (3S,5R,8S)-




63.
236391-76-7
Acetic acid, 2-(1-oxopropoxy)-, 1-
Romandolide ®
0.00012400




(3,3-dimethylcyclohexyl)ethyl ester




64.
115-71-9
2-Penten-1-ol, 5-[(1R,3R,6S)-2,3-
cis-alpha-
0.00011800




dimethyltricyclo[2.2.1.02,6]hept-
Santalol





3-yl]-2-methyl-, (2Z)-




65.
107898-54-4
4-Penten-2-ol, 3,3-dimethyl-5-
Polysantol ®
0.00011700




(2,2,3-trimethyl-3-cyclopenten-1-yl)-




66.
69486-14-2
5,8-Methano-2H-1-benzopyran-
Florex ®
0.00011000




2-one, 6-ethylideneoctahydro-




67.
84697-09-6
Heptanal, 2-[(4-methylphenyl)
Acalea
0.00010100




methylene]-




68.
14595-54-1
4-Cyclopentadecen-1-one, (Z)-
Exaltenone
0.00009640


69.
32388-55-9
Ethanone, 1-[(3R,3aR,7R,8aS)-
Vertofix ®
0.00008490




2,3,4,7,8,8a-hexahydro-3,6,8,8-






telramethyl-1H-3a,7-






methanoazulen-5-yl]-




70.
131812-67-4
1,3-Dioxolane, 2,4-dimethyl-2-
Okoumal ®
0.00007600




(5,6,7,8-tetrahydro-5,5,8,8-






tetramethyl-2-naphthalenyl)-




71.
106-02-5
Oxacyclohexadecan-2-one
Exaltolide ®
0.00006430


72.
141773-73-1
1-Propanol, 2-[1-(3,3-
Helvetolide ®
0.00005790




dimethylcyclohexyl)ethoxy]-2-






methyl-, 1-propanoate




73.
63314-79-4
5-Cyclopentadecen-1-
Delta
0.00005650




one, 3-methyl-
Muscenone



74.
77-42-9
2-Penten-1-ol, 2-methyl-5-
cis-beta-
0.00004810




[(1S,2R,4R)-2-methyl-3-
Santalol





methylenebicyclo[2.2.1]






hept-2-yl], (2Z)-




75.
362467-67-2
2H-1,5-Benzodioxepin-3(4H)-
Azurone
0.00004770




one, 7-(3-methylbutyl)-




76.
28371-99-5
Ethanone, 1-(2,6,10-trimethyl-
Trimofix O
0.00004580




2,5,9-cyclododecatrien-1-yl)-




77.
16223-63-5
1H-3a,6-Methanoaxulene-3-
Khusimol
0.00004400




methanol, octahydro-7,7-






dimethyl-8-methylene-,






(3S,3aR,6R,8aS)-




78.
10461-98-0
Benzeneacetonitrile,
Peonile
0.00004290




α-cyclohexylidene-




79.
50607-64-2
Benzoic acid, 2-[(2-
Mevantraal
0.00004070




methylpentylidene)






amino]-, methyl ester




80.
29895-73-6
5-Hydroxy-2-benzyl-
Acetal CD
0.00004050




1,3-dioxane




81.
94-47-3
Benzoic acid, 2-
Phenyl Ethyl
0.00003480




phenylethyl ester
Benzoate



82.
3100-36-5
Cyclohexadec-8-en-1-one
Globanone ®
0.00003310


83.
37609-25-9
5-Cyclohexadecen-1-One
Ambretone
0.00003310


84.
66072-32-0
Cyclohexanol, 4-
Iso Bornyl
0.00003010




(1,7,7-trimethylbicyclo
Cyclohexanol





[2.2.1]hept-2-yl)-




85.
31906-04-4
3-Cyclohexene-1-
Lyral ®
0.00002940




carboxaldehyde, 4-(4-






hydroxy-4-methylpentyl)-




86.
21145-77-7
Ethanone, 1-(5,6,7,8-
Musk Plus
0.00002860




tetrahydro-3,5,5,6,8,8-






hexamethyl-2-naphthalenyl)-




87.
21145-77-7
Ethanone, 1-(5,6,7,8-
Fixolide
0.00002860




tetrahydro-3,5,5,6,8,8-






hexamethyl-2-naphthalenyl)-




88.
22442-01-0
2-Cyclopentadecen-
Museenone
0.00002770




1-one, 3-methyl-




89.
109-29-5
Oxacycloheptadecan-2-one
Silvanone Ci
0.00002600


90.
101-94-0
Benzeneacetic acid,
Para Cresyl
0.00002330




4-methylphenyl ester
Phenyl Acetate



91.
102-20-5
Benzeneacetic acid,
Phenyl Ethyl
0.00002300




2-phenylethyl ester
Phenyl Acetate



92.
118562-73-5
Cyclododecaneethanol,
Hydroxyambran
0.00001800




β-methyl-




93.
103-41-3
2-Propenoic acid,
Benzyl
0.00001050




3-phenyl-, phenyl methyl ester
Cinnamate



94.
4707-47-5
Benzoic acid, 2,4-dihydroxy-
Veramoss
0.00001050




3,6-dimethyl-, methyl ester




95.
183551-83-9
Naphtho[2,1-b]furan-6(7H)-
Myrrhone
0.00000977




one, 8,9-dihydro-1,5,8-






trimethyl-, (8R)-




96.
102-17-0
Benzeneacetic acid, (4-
Para Anisyl
0.00000813




methoxyphenyl)methyl ester
Phenyl Acetate



97.
120-11-6
Benzene, 2-methoxy-1-
Benzyl Iso
0.00000676




(phenylmethoxy)-4-(1-propen-1-yl)-
Eugenol



98.
102-22-7
Benzeneacetic acid, (2E)-
Geranyl
0.00000645




3,7-dimethyl-2,6-octadien-1-yl ester
Phenylacetate



99.
111879-80-2
Oxacyclohexadec-12-en-2-
Habanolide
0.00000431




one, (12E)-
100%



100.
87-22-9
Benzoic acid, 2-hydroxy-,
Phenyl Ethyl
0.00000299




2-phenylethyl ester
Salicylate



101.
78-37-5
2-Propenoic acid, 3-phenyl-,
Linalyl
0.00000174




1-ethenyl-1,5-dimethyl-
Cinnamate





4-hexen-1-yl ester




102.
28645-51-4
Oxacycloheptadec-10-en-2-one
Ambrettolide
0.00000139


103.
123-69-3
Oxacycloheptadec-8-en-2-one,
Ambrettolide
0.00000136




(8Z)-




104.
3391-83-1
1,7-Dioxacycloheptadecan-
Musk RI
0.00000057




8-one




105.
68527-79-7
7-Oclen-2-ol, 8-(1H-indol-
Indolene
0.000000445




1-yl)-2,6-dimethyl-




106.
89-43-0
Methyl 2-[(7-hydroxy-3,7-
Aurantinol
0.0000000100




dimethyloctylidene)amino]benzoate




107.
54982-83-1
1,4-Dioxacyclohexadecane-5,16-dione
Zenolide
0.00000000834


108.
105-95-3
1,4-Dioxacycloheptadecane-5,17-dione
Ethylene
0.00000000313





Brassylate



109.
3681-73-0
Hexadecanoic acid, (2E)-3,7-
Hexarose
0.00000000300




dimethyl-2,6-ocladien-1-yl ester




110.
4159-29-9
Phenol, 4-[3-(benzoyloxy)-1-
Coniferyl
0.00000000170




propen-1-yl]-2-methoxy-
benzoate



111.
144761-91-1
Benzoic acid, 2-[(1-hydroxy-
Trifone
0.00000000093




3-phenylbutyl)amino]-, methyl ester
DIPG






1 Non-limiting examples of alternative qualities from various suppliers can be purchased under the following tradenames: Kharismal ® Super (IFF), Kharismal ® (IFF), Hedione ® (Firmenich), Hedione ® HC (Firmenich), Paradisone (Firmenich), Cepionate (Zenon), Super cepionate (Zenon), Claigeon ® (Zenon).



*Vapor Pressures are acquired as described in the Test Methods Section.


**Origin: The low volatile fragrance materials may be obtained from one or more of the following companies: Firmenich (Geneva, Switzerland), Symrise AG (Holzminden, Germany), Givaudan (Argenleuil, France), IFF (Hazlet, New Jersey), Bedoukian (Danbury, Connecticut), Sigma Aldrich (St. Louis, Missouri), Millennium Speciality Chemicals (Olympia Fields, Illinois), Polarone International (Jersey City, New Jersey), and Aroma & Flavor Specialities (Danbury, Connecticut).






(ii) Volatile Fragrance Materials


Fragrance materials classified as “volatile fragrance materials” are ones having a vapor pressure greater than or equal to 0.001 Torr (0.000133 kPa) at 25° C. Preferably, the volatile fragrance materials is present in an amount of from about 70 wt % to about 99.9 wt %, preferably greater than about 80 wt %, or more preferably greater than about 88 wt %, relative to the total weight of the fragrance component. Preferably, the volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials, or at least 5 materials, or at least 7 materials as disclosed in Table 3.









TABLE 3







Volatile Fragrance Materials












CAS


Vapor Pressure


No.
Number
IUPAC Name
Common Name**
(Torr at 25° C.)*














1.
107-31-3
Formic acid, methyl ester
Methyl Formate
732.00000000


2.
75-18-3
Methane, 1,1′-thiobis-
Dimethyl Sulfide
647.00000000





1.0% In DEP



3.
141-78-6
Acetic acid ethyl ester
Ethyl Acetate
112.00000000


4.
105-37-3
Propanoic acid, ethyl
Ethyl Propionate
44.50000000




ester




5.
110-19-0
Acetic acid, 2-
Isobutyl Acetate
18.00000000




methylpropyl ester




6.
105-54-4
Butanoic acid,
Ethyl Butyrate
13.90000000




ethyl ester




7.
14765-30-1
1-Butanol
Butyl Alcohol
8.52000000


8.
7452-79-1
Butanoic acid, 2-
Ethyl-2-Methyl
7.85000000




methyl-, ethyl ester
Butyrate



9.
123-92-2
1-Butanol, 3-methyl-,
Iso Amyl Acetate
5.68000000




1-acetate




10.
66576-71-4
Butanoic acid, 2-methyl-,
Iso Propyl 2-
5.10000000




1-methylethyl ester
Methylbulyrate



11.
110-43-0
2-Heptanone
Methyl Amyl
4.73000000





Ketone



12.
6728-26-3
2-Hexenal, (2E)-
Trans-2 Hexenal
4.62000000


13.
123-51-3
1-Butanol, 3-methyl-
Isoamyl Alcohol
4.16000000


14.
1191-16-8
2-Buten-1-ol, 3-
Prenyl acetate
3.99000000




methyl-, 1-acetate




15.
57366-77-5
1,3-Dioxolane-2-
Methyl Dioxolan
3.88000000




methanamine, N-methyl-




16.
7785-70-8
Bicyclo[3.1.1]hept-2-
Alpha Pinene
3.49000000




ene, 2,6,6-trimethyl-, (1R,5R)-




17.
79-92-5
Bicyclo[2.2.1]heptane,
Camphene
3.38000000




2,2-dimethyl-3-methylene-




18.
94087-83-9
2-Butanethiol,
4-Methoxy-2-
3.31000000




4-methoxy-2-methyl-
Methyl-2-






Butanenthiol



19.
39255-32-8
Pentanoic acid,
Manzanate
2.91000000




2-methyl-, ethyl ester




20.
3387-41-5
Bicyclo[3.1.0]hexane, 4-
Sabinene
2.63000000




methylene-1-(1-methylethyl)-




21.
127-91-3
Bicyclo[3.1.1]heptane,
Beta
2.40000000




6-dimethyl-2-methylene-
Pinene



22.
105-68-0
1-Butanol, 3-methyl-,
Amyl
2.36000000




1-propanoate
Propionate



23.
123-35-3
1,6-Octadiene, 7-
Myrcene
2.29000000




methyl-3-methylene-




24.
124-13-0
Octanal
Octyl Aldehyde
2.07000000


25.
7392-19-0
2H-Pyran, 2-
Limetol
1.90000000




ethenyltetrahydro-






2,6,6-trimethyl-




26.
111-13-7
2-Octanone
Methyl Hexyl
1.72000000





Ketone



27.
123-66-0
Hexanoic acid,
Ethyl
1.66000000




ethyl ester
Caproate



28.
470-82-6
2-Oxabicyclo[2.2.2]
Eucalyptol
1.65000000




octane, 1,3,3-trimethyl-




29.
99-87-6
Benzene, 1-methyl-4-
Para Cymene
1.65000000




(1-methylethyl)-




30.
104-93-8
Benzene, 1-methoxy-
Para Cresyl
1.65000000




4-methyl-
Methyl Ether



31.
13877-91-3
1,3,6-Octatriene,
Ocimene
1.56000000




3,7-dimethyl-




32.
138-86-3
Cyclohexene, 1-methyl-
dl-Limonene
1.54000000




4-(1-methylethenyl)-




33.
5989-27-5
Cyclohexene, 1-methyl-
d-limonene
1.54000000




4-(1-methylethenyl)-, (4R)-




34.
106-68-3
3-Octanone
Ethyl Amyl
1.50000000





Ketone



35.
110-41-8
Undecanal, 2-methyl-
Methyl Nonyl
1.43000000





Acetaldehyde



36.
142-92-7
Acetic acid, hexyl esler
Hexyl acetate
1.39000000


37.
110-93-0
5-Hepten-2-one, 6-methyl-
Methyl
1.28000000





Heptenone



38.
81925-81-7
2-Hepten-4-one, 5-methyl-
Filbertone
1.25000000





1% in TEC



39.
3681-71-8
3-Hexen-1-ol, 1-acetate, (3Z)-
cis-3-
1.22000000





Hexenyl acetate



40.
97-64-3
Propanoic acid, 2-hydroxy-,
Ethyl
1.16000000




ethyl ester
Lactate



41.
586-62-9
Cyclohexene, 1-methyl-
Terpineolene
1.13000000




4-(1-methylethylidene)-




42.
51115-64-1
Butanoic acid, 2-
Amyl butyrate
1.09000000




methylbutyl ester




43.
106-27-4
Butanoic acid, 3-
Amyl
1.09000000




methylbutyl ester
Butyrate



44.
99-85-4
1,4-Cyclohexadiene,
Gamma
1.08000000




1-methyl-4-(1-methylethyl)-
Terpinene



45.
18640-74-9
Thiazole, 2-(2-methylpropyl)-
2-
1.07000000





Isobutylthiazole



46.
928-96-1
3-Hexen-1-ol, (3Z)-
cis-3-Hexenol
1.04000000


47.
100-52-7
Benzaldehyde
Benzaldehyde
0.97400000


48.
141-97-9
Butanoic acid, 3-oxo-,
Ethyl
0.89000000




ethyl ester
Acetoacetate



49.
928-95-0
2-Hexen-1-ol, (2E)-
Trans-2-Hexenol
0.87300000


50.
928-94-9
2-Hexen-1-ol, (2Z)-
Beta Gamma
0.87300000





Hexenol



51.
24691-15-4
Cyclohexane, 3-ethoxy-1,
Herbavert
0.85200000




1,5-trimethyl-, cis-(9CI)




52.
19872-52-7
2-Pentanone, 4-
4-Methyl-4-
0.84300000




mercapto-4-methyl-
Mercaptopenlan-






2-one 1 ppm TEC



53.
3016-19-1
2,4,6-Octatriene,
Allo-Ocimene
0.81600000




2,6-dimethyl-, (4E,6E)-




54.
69103-20-4
Oxirane, 2,2-dimethyl-
Myroxide
0.80600000




3-(3-methyl-2,4-pentadien-






1-yl)-




55.
189440-77-5
4,7-Octadienoic acid,
Anapear
0.77700000




methyl ester, (4E)-




56.
67633-96-9
Carbonic acid, (3Z)-3-
Liffarome ™
0.72100000




hexen-1-yl methyl ester




57.
123-68-2
Hexanoic acid, 2-propen-
Allyl
0.67800000




1-yl ester
Caproate



58.
106-72-9
5-Heptenal, 2,6-dimethyl-
Melonal
0.62200000


59.
106-30-9
Heptanoic acid, ethyl ester
Ethyl
0.60200000





Oenanthate



60.
68039-49-6
3-Cyclohexene-1-
Ligustral or
0.57800000




carboxaldehyde, 2,4-dimethyl-
Triplal



61.
101-48-4
Benzene, (2,2-
Phenyl
0.55600000




dimethoxyethyl)-
Acetaldehyde






Dimethyl






Acetal



62.
16409-43-1
2H-Pyran, tetrahydro-4-
Rose Oxide
0.55100000




methyl-2-(2-methyl-1-






propen-1-yl)-




63.
925-78-0
3-Nonanone
Ethyl Hexyl
0.55100000





Ketone



64.
100-47-0
Benzonitrile
Benzyl Nitrile
0.52400000


65.
589-98-0
3-Octanol
Octanol-3
0.51200000


66.
58430-94-7
1-Hexanol, 3,5,5-trimethyl-,
Iso Nonyl
0.47000000




1-acetate
Acetate



67.
10250-45-0
4-Heptanol, 2,6-dimethyl-,
Alicate
0.45400000




4-acetate




68.
105-79-3
Hexanoic acid, 2-
Iso Butyl
0.41300000




methylpropyl ester
Caproate



69.
2349-07-7
Propanoic acid, 2-methyl-,
Hexyl
0.41300000




hexyl ester
isobulyrate



70.
23250-42-2
Cyclohexanecarboxylic acid,
Cyprissate
0.40500000




1,4-dimethyl-, methyl






ester, trans-




71.
122-78-1
Benzeneacetaldehyde
Phenyl
0.36800000





acetaldehyde



72.
5405-41-4
Butanoic acid, 3-hydroxy-,
Ethyl-3-
0.36200000




ethyl ester
Hydroxy






Butyrate



73.
105-53-3
Propanedioic acid, 1,3-
Diethyl
0.34400000




diethyl ester
Malonate



74.
93-58-3
Benzoic acid, methyl
Methyl
0.34000000




ester
Benzoate



75.
16356-11-9
1,3,5-Undecatriene
Undecatriene
0.33600000


76.
65405-70-1
4-Decenal, (4E)-
Decenal
0.33100000





(Trans-4)



77.
54546-26-8
1,3-Dioxane, 2-butyl-
Herboxane
0.33000000




4,4,6-trimethyl-




78.
13254-34-7
2-Heptanol, 2,6-dimethyl-
Dimethyl-2,6-
0.33000000





Heptan-2-ol



79.
98-86-2
Ethanone, 1-phenyl-
Acetophenone
0.29900000


80.
93-53-8
Benzeneacetaldehyde,
Hydratropic
0.29400000




α-methyl-
aldehyde



81.
80118-06-5
Propanoic acid, 2-methyl-,
Iso Pentyrate
0.28500000




1,3-dimethyl-3-buten-1-yl ester




82.
557-48-2
2,6-Nonadienal, (2E,6Z)-
EZ-2,6-
0.28000000





Nonadien-1-al



83.
24683-00-9
Pyrazine, 2-methoxy-3-
2-Methoxy-
0.27300000




(2-methylpropyl)-
3-Isobutyl






Pyrazine



84.
104-57-4
Formic acid, phenylmethyl
Benzyl
0.27300000




ester
Formate



85.
104-45-0
Benzene, 1-methoxy-4-propyl-
Dihydroanethole
0.26600000


86.
491-07-6
Cyclohexanone, 5-methyl-2-
Iso Menthone
0.25600000




(1-methylethyl)-, (2R,5R)-rel-




87.
89-80-5
Cyclohexanone, 5-methyl-2-
Menthone
0.25600000




(1-methylethyl)-, (2R,5S)-rel-
Racemic



88.
2463-53-8
2-Nonenal
2 Nonen-1-al
0.25600000


89.
55739-89-4
Cyclohexanone, 2-ethyl-
Thuyacetone
0.25000000




4,4-dimethyl-




90.
150-78-7
Benzene, 1,4-dimelhoxy-
Hydroquinone
0.25000000





Dimethyl Ether



91.
64988-06-3
Benzene, 1-(ethoxymethyl)-
Rosacene
0.24600000




2-methoxy-




92.
76-22-2
Bicyclo[2.2.1]heptan-2-
Camphor
0.22500000




one, 1,7,7-trimethyl-
gum



93.
67674-46-8
2-Hexene, 6,6-dimethoxy-
Methyl
0.21400000




2,5,5-trimethyl-
Pamplemousse



94.
112-31-2
Decanal
Decyl Aldehyde
0.20700000


95.
16251-77-7
Benzenepropanal,
Trifernal
0.20600000




β-methyl-




96.
93-92-5
Benzenemethanol,
Methyl-
0.20300000




α-methyl-, 1-acetate
phenylcarbinol






Acetate



97.
143-13-5
Acetic acid, nonyl ester
Nonyl Acetate
0.19700000


98.
122-00-9
Ethanone, 1-(4-
Para Methyl
0.18700000




methylphenyl)-
Acetophenone



99.
24237-00-1
2H-Pyran, 6-butyl-3,
Gyrane
0.18600000




6-dihydro-2,4-dimethyl-




100.
41519-23-7
Propanoic acid, 2-
Hexenyl
0.18200000




methyl-, (3Z)-3-hexen-1-yl ester
Isobutyrate



101.
93-89-0
Benzoic acid, ethyl ester
Ethyl Benzoate
0.18000000


102.
20780-48-7
3-Octanol, 3,7-dimethyl-,
Tetrahydro
0.18000000




3-acetate
Linalyl Acetate



103.
101-41-7
Methyl 2-phenylacetate
Methylphenyl
0.17600000





acetate



104.
40853-55-2
1-Hexanol, 5-methyl-
Tetrahydro
0.17300000




2-(1-methylethyl)-, 1-acetate
Lavandulyl






Acetate



105.
933-48-2
Cyclohexanol, 3,3,5-
Trimethyl-
0.17300000




trimethyl-, (1R,5R)-rel-
cyclohexanol



106.
35158-25-9
2-Hexenal, 5-methyl-2-
Lactone of
0.17200000




(1-methylethyl)-
Cis Jasmone



107.
18479-58-8
7-Octen-2-ol, 2,6-dimethyl-
Dihydromyrcenol
0.16600000


108.
140-11-4
Acetic acid, phenylmethyl
Benzyl acetate
0.16400000




ester




109.
14765-30-1
Cyclohexanone, 2-
2-sec-Butyl Cyclo
0.16300000




(1-methylpropyl)-
Hexanone



110.
20125-84-2
3-Octen-1-ol, (3Z)-
Octenol
0.16000000


111.
142-19-8
Heptanoic acid, 2-
Allyl
0.16000000




propen-1-yl ester
Heptoate



112.
100-51-6
Benzenemethanol
Benzyl Alcohol
0.15800000


113.
10032-15-2
Butanoic acid, 2-
Hexyl-2-Methyl
0.15800000




methyl-, hexyl ester
Butyrate



114.
695-06-7
2(3H)-Furanone,
Gamma
0.15200000




5-ethyldihydro-
Hexalactone



115.
21722-83-8
Cyclohexaneethanol,
Cyclohexyl
0.15200000




1-acetate
Ethyl Acetate



116.
111-79-5
2-Nonenoic acid,
Methyl-2-
0.14600000




methyl ester
Nonenoate



117.
16491-36-4
Butanoic acid, (3Z)-
Cis 3 Hexenyl
0.13500000




3-hexen-1-yl ester
Butyrate



118.
111-12-6
2-Octynoic acid,
Methyl Heptine
0.12500000




methyl ester
Carbonate



119.
59323-76-1
1,3-Oxathiane, 2-methyl-
Oxane
0.12300000




4-propyl-, (2R,4S)-rel-




120.
62439-41-2
Heptanal, 6-methoxy-
Methoxy
0.11900000




2,6-dimethyl-
Melonal



121.
13851-11-1
Bicyclo[2.2.1]heptan-2-ol,
Fenchyl
0.11700000




1,3,3-trimethyl-, 2-acetate
Acetate



122.
115-95-7
1,6-Octadien-3-ol,
Linalyl acetate
0.11600000




3,7-dimethyl-, 3-acetate




123.
18479-57-7
2-Octanol, 2,6-dimethyl-
Tetra-Hydro
0.11500000





Myrcenol



124.
78-69-3
3,7-dimethyloctan-3-ol
Tetra-Hydro
0.11500000





Linalool



125.
111-87-5
1-Oclanol
Octyl Alcohol
0.11400000


126.
71159-90-5
3-Cyclohexene-1-
Grapefruit
0.10500000




methanethiol, α,α,4-trimethyl-
mercaptan



127.
80-25-1
Cyclohexanemethanol,
Menthanyl
0.10300000




α,α,4-trimethyl-, 1-acelate
Acetate



128.
88-41-5
Cyclohexanol, 2-(1,1-
Verdox ™
0.10300000




dimethylethyl)-, 1-acetate




129.
32210-23-4
Cyclohexanol, 4-(1,1-
Vertenex
0.10300000




dimethylethyl)-, 1-acetate




130.
112-44-7
Undecanal
n-Undecanal
0.10200000


131.
24168-70-5
Pyrazine, 2-methoxy-3-
Methoxy-
0.09950000




(1-methylpropyl)-
isobutylpyrazine



132.
89-79-2
Cyclohexanol, 5-methyl-
Iso-Pulegol
0.09930000




2-(1-methylethenyl)-,






(1R,2S,5R)-




133.
112-12-9
2-Undecanone
Methyl Nonyl
0.09780000





Ketone



134.
103-05-9
Benzenepropanol,
Phenyl Ethyl
0.09770000




α,α-dimethyl-
Dimethyl






Carbinol



135.
125-12-2
Bicyclo[2.2.1]heptan-2-ol,
Iso Bornyl
0.09590000




1,7,7-trimethyl-, 2-acetate,
Acetate





(1R,2R,4R)-rel-




136.
78-70-6
l,6-Octadien-3-ol,
Linalool
0.09050000




3,7-dimethyl-




137.
101-97-3
Benzeneacetic acid,
Ethyl Phenyl
0.08970000




ethyl ester
Acetate



138.
100-86-7
Benzeneelhanol,
Dimethyl
0.08880000




α,α-dimethyl-
Benzyl Carbinol



139.
188570-78-7
Cyclopropanecarboxylic
Montaverdi
0.08640000




acid, (3Z)-3-hexen-1-yl ester




140.
67634-25-7
3-Cyclohexene-1-methanol,
Floralate
0.08500000




3,5-dimethyl-, 1-acetate




141.
112-44-7
Undecanal
Undecyl
0.08320000





Aldehyde



142.
32669-00-4
Ethanone, 1-(3-
Tanaisone ®
0.08150000




cycloocten-1-yl)-




143.
98-53-3
Cyclohexanone, 4-(1,1-
Patchi
0.07780000




dimethylethyl)-




144.
35854-86-5
6-Nonen-1-ol, (6Z)-
cis-6-None-1-ol
0.07770000


145.
5331-14-6
Benzene, (2-butoxyethyl)-
Butyl phenethyl
0.07760000





ether



146.
80-57-9
Bicyclo[3.1.1]hept-3-
Verbenone
0.07730000




en-2-one, 4,6,6-trimethyl-




147.
22471-55-2
Cyclohexanecarboxylic
Thesaron
0.07670000




acid, 2,2,6-trimethyl-,






ethyl ester, (1R,6S)-rel-




148.
60-12-8
2-phenyl ethanol
Phenelhyl
0.07410000





alcohol or






Phenylethyl






alcohol



149.
106-26-3
2,6-Octadienal, 3,7-
Neral
0.07120000




dimethyl-, (2Z)-




150.
5392-40-5
2,6-Octadienal, 3,7-
Citral
0.07120000




dimethyl-




151.
89-48-5
Cyclohexanol, 5-methyl-
Menthyl
0.07070000




2-(1-methylethyl)-, 1-
Acetate





acetate, (1R,2S,5R)-rel-




152.
119-36-8
Benzoic acid, 2-hydroxy-,
Methyl
0.07000000




methyl ester
salicylate



153.
4180-23-8
Benzene, 1-methoxy-
Anethol
0.06870000




4-(1E)-1-propen-1-yl-




154.
7549-37-3
2,6-Octadiene, 1,1-
Citral Dimethyl
0.06780000




dimethoxy-3,7-dimethyl-
Acetal



155.
25225-08-5
Cyclohexanemethanol,
Aphermate
0.06780000




α,3,3-trimethyl-, 1-formate




156.
3913-81-3
2-Decenal, (2E)-
2-Decene-1-al
0.06740000


157.
15373-31-6
3-Cyclopentene-1-acetonitrile,
Cantryl ®
0.06700000




2,2,3-trimethyl-




158.
6485-40-1
2-Cyclohexen-1-one, 2-methyl-
Laevo
0.06560000




5-(1-methylethenyl)-, (5R)-
carvone



159.
16587-71-6
Cyclohexanone, 4-
Orivone
0.06490000




(1,1-dimethylpropyl)-




160.
62406-73-9
6,10-Dioxaspiro[4.5]decane,
Opalal CI
0.06290000




8,8-dimethyl-7-(1-methylethyl)-




161.
3720-16-9
2-Cyclohexen-1-one, 3-
Livescone
0.06270000




methyl-5-propyl-




162.
13816-33-6
Benzonitrile, 4-(1-
Cumin
0.06230000




methylethyl)-
Nitrile



163.
67019-89-0
2,6-Nonadienenitrile
Violet Nitrile
0.06200000


164.
53398-85-9
Butanoic acid, 2-methyl-,
cis-3-Hexenyl
0.06130000




(3Z)-3-hexen-1-yl ester
Alpha






Methyl Bulyrate



165.
208041-98-9
Heptanenitrile, 2-propyl-
Jasmonitrile
0.05920000


166.
16510-27-3
Benzene, 1-
Toscanol
0.05870000




(cyclopropylmethyl)-4-






methoxy-




167.
111-80-8
2-Nonynoic acid,
Methyl Octine
0.05680000




methyl ester
Carbonate



168.
103-45-7
Acetic acid, 2-
Phenyl Ethyl
0.05640000




phenylethyl ester
Acetate



169.
2550-26-7
2-Butanone, 4-phenyl-
Benzyl Acetone
0.05570000


170.
13491-79-7
Cyclohexanol, 2-(1,1-
Verdol
0.05430000




dimethylethyl)-




171.
7786-44-9
2,6-Nonadien-1-ol
2,6-Nonadien-1-ol
0.05370000


172.
103-28-6
Propanoic acid, 2-methyl-,
Benzyl Iso
0.05130000




phenylmethyl ester
Butyrate



173.
104-62-1
Formic acid, 2-
Phenyl Ethyl
0.05050000




phenylethyl ester
Formate



174.
28462-85-3
Bicyclo[2.2.1]heptan-2-ol,
Humus Ether
0.04870000




1,2,3,3-tetramethyl-, (1R,






2R,4S)-rel-




175.
122-03-2
Benzaldehyde, 4-(1-
Cuminic
0.04820000




methylethyl)-
Aldehyde



176.
358331-95-0
2,5-Octadien-4-one, 5,6,7-
Pomarose
0.04810000




trimethyl-, (2E)-




177.
562-74-3
3-Cyclohexen-1-ol, 4-
Terpinenol-4
0.04780000




methyl-1-(1-methylethyl)-




178.
68527-77-5
3-Cyclohexene-1-methanol,
Isocyclogeraniol
0.04640000




2,4,6-trimethyl-




179.
35852-46-1
Pentanoic acid, (3Z)-
Cis-3-Hexenyl
0.04580000




3-hexen-1-yl ester
Valerate



180.
2756-56-1
Bicyclo[2.2.1]heptan-2-ol,
Iso Bornyl
0.04540000




1,7,7-trimethyl-, 2-
Propionate





propanoate, (1R,2R,4R)-rel-




181.
14374-92-6
Benzene, 1-methyl-4-(1-
Verdoracine
0.04460000




methylethyl)-2-(1-propen-1-yl)-




182.
6784-13-0
3-Cyclohexene-1-propanal,
Limonenal
0.04380000




β,4-dimethyl-




183.
8000-41-7
2-(4-methyl-1-cyclohex-3-
Alpha
0.04320000




enyl)propan-2-ol
Terpineol



184.
41884-28-0
1-Hexanol, 5-methyl-
Tetrahydro
0.04230000




2-(1-methylethyl)-, (2R)-
Lavandulol



185.
22457-23-4
3-Heptanone, 5-methyl-,
Stemone ®
0.04140000




oxime




186.
104-50-7
2(3H)-Furanone, 5-
Gamma
0.04080000




butyldihydro-
Octalactone



187.
143-08-8
1-Nonanol
Nonyl Alcohol
0.04070000


188.
3613-30-7
Octanal, 7-methoxy-
Methoxy-
0.04020000




3,7-dimethyl-
citronellal



189.
67634-00-8
Acetic acid, 2-(3-
Allyl Amyl
0.04000000




methylbutoxy)-, 2-
Glycolate





propen-1-yl ester




190.
464-45-9
Bicyclo[2.2.1]heptan-2-
1-Borneol
0.03980000




ol, 1,7,7-trimethyl-,(1S,2R,4S)-




191.
124-76-5
Bicyclo[2.2.1]heptan-2-ol,
1.7.7-Trimethyl-
0.03980000




1,7,7-trimethyl-, (1R,2R,4R)-rel-
Bicyclo-1.2.2-






Heptanol-2



192.
67874-72-0
Cyclohexanol, 2-(1,1-
Coniferan
0.03980000




dimethylpropyl)-, 1-acetate




193.
80-26-2
3-Cyclohexene-1-
Terpinyl
0.03920000




methanol, α,α,4-trimethyl-,
Acetate





1-acetate




194.
498-81-7
Cyclohexanemethanol,
Dihydro
0.03920000




α,α,4-trimethyl-
Terpineol



195.
112-45-8
10-Undecenal
Undecylenic
0.03900000





aldehyde



196.
35044-57-6
2,4-Cyclohexadiene-1-
Ethyl
0.03880000




carboxylic acid, 2,6,6-
Safranate





trimethyl-, ethyl ester




197.
106-21-8
1-Octanol, 3,7-dimethyl-
Dimethyl
0.03860000





Octanol



198.
84560-00-9
Cyclopentanol, 2-pentyl-
Cyclopentol
0.03790000


199.
82461-14-1
Furan, tetrahydro-2,4-
Rhubafuran ®
0.03780000




dimethyl-4-phenyl-




200.
56011-02-0
Benzene, [2-(3-
Phenyl Ethyl
0.03690000




methylbutoxy)ethyl]-
Isoamyl Ether



201.
103-37-7
Butanoic acid,
Benzyl
0.03660000




phenylmethyl ester
Butyrate



202.
6378-65-0
Hexyl hexanoate
Hexyl hexanoate
0.03490000


203.
118-61-6
Benzoic acid, 2-hydroxy-,
Ethyl salicylate
0.03480000




ethyl ester




204.
98-52-2
Cyclohexanol, 4-
Patchon
0.03480000




(1,1-dimethylethyl)-




205.
115-99-1
1,6-Octadien-3-ol,
Linalyl
0.03440000




3,7-dimethyl-, 3-formate
Formate



206.
112-54-9
Dodecanal
Lauric Aldehyde
0.03440000


207.
53046-97-2
3,6-Nonadien-1-ol, (3Z,6Z)-
3,6 Nonadien-1-ol
0.03360000


208.
76649-25-7
3,6-Nonadien-1-ol
3,6-Nonadien-1-ol
0.03360000


209.
141-25-3
3,7-Dimethyloct-6-en-1-ol
Rhodinol
0.03290000


210.
1975-78-6
Decanenitrile
Decanonitrile
0.03250000


211.
2216-51-5
Cyclohexanol, 5-
L-Menthol
0.03230000




methyl-2-(1-






methylethyl)-(1R,2S,5R)-




212.
3658-77-3
4-hydroxy-2,5-
Pineapple
0.03200000




dimethylfuran-3-one
Ketone



213.
103-93-5
Propanoic acid, 2-methyl-,
Para Cresyl
0.03120000




4-methylphenyl ester
iso-Butyrate



214.
24717-86-0
Propanoic acid, 2-methyl-,
Abierate
0.03110000




(1R,2S,4R)-1,7,7-






trimethylbicyclo[2.2.1]






hept-2-yl ester, rel-




215.
67845-46-9
Acetaldehyde, 2-(4-
Aldehyde
0.03090000




methylphenoxy)-
XI



216.
67883-79-8
2-Butenoic acid, 2-methyl-,
Cis-3-Hexenyl
0.03060000




(3Z)-3-hexen-1-yl ester, (2E)-
Tiglate



217.
33885-51-7
Bicyclo[3.1.1]hept-2-
Pino
0.03040000




ene-2-propanal, 6,6-dimethyl-
Acetaldehyde



218.
105-85-1
6-Octen-1-ol, 3,7-
Citronellyl
0.03000000




dimethyl-, 1-formate
Formate



219.
70214-77-6
2-Nonanol, 6,8-dimethyl-
Nonadyl
0.03010000


220.
215231-33-7
Cyclohexanol, 1-methyl-
Rossitol
0.02990000




3-(2-methylpropyl)-




221.
120-72-9
1H-Indole
Indole
0.02980000


222.
2463-77-6
2-Undecenal
2-Undecene-
0.02970000





1-al



223.
675-09-2
2H-Pyran-2-one,
Levistamel
0.02940000




4,6-dimethyl-




224.
98-55-5
3-Cyclohexene-1-
Alpha-
0.02830000




methanol, α,α,4-trimethyl-
Terpineol



225.
81786-73-4
3-Hepten-2-one,
Koavone
0.02750000




3,4,5,6,6-pentamethyl-, (3Z)-




226.
122-97-4
Benzenepropanol
Phenyl Propyl
0.02710000





Alcohol



227.
39212-23-2
2(3H)-Furanone, 5-
Methyl
0.02700000




butyldihydro-4-methyl-
Octalactone



228.
53767-93-4
7-Octen-2-ol, 2,6-dimethyl-,
Dihydro
0.02690000




2-acetate
Terpinyl Acetate



229.
35044-59-8
1,3-Cyclohexadiene-1-
Ethyl
0.02660000




carboxylic acid, 2,6,6-
Safranate





trimethyl-, ethyl ester




230.
104-55-2
2-Propenal, 3-phenyl-
Cinnamic
0.02650000





Aldehyde



231.
144-39-8
1,6-Octadien-3-ol,
I.inalyl
0.02630000




3,7-dimethyl-, 3-propanoate
Propionate



232.
61931-80-4
1,6-Nonadien-3-ol,
3,7-Dimethyl-
0.02630000




3,7-dimethyl-, 3-acetate
1,6-nonadien-






3-yl acetate



233.
102-13-6
Benzeneacetic acid,
Iso Butyl
0.02630000




2-methylpropyl ester
Phenylacetate



234.
65443-14-3
Cyclopentanone, 2,2,5-
Veloutone
0.02610000




trimethyl-5-pentyl-




235.
141-12-8
2,6-Octadien-1-ol, 3,7-
Neryl
0.02560000




dimethyl-, 1-acetate, (2Z)-
Acetate



236.
105-87-3
2,6-Octadien-1-ol, 3,7-
Geranyl
0.02560000




dimethyl-, 1-acetate, (2E)-
acetate



237.
68141-17-3
Undecane, 1,1-
Methyl Nonyl
0.02550000




dimethoxy-2-methyl-
Acetaldehyde






Dimethyl Acetal



238.
2206-94-2
Benzenemethanol, α-
Indocolore
0.02550000




methylene-, 1-acetate




239.
10528-67-3
Cyclohexanepropanol,
Cyclohexyl-
0.02550000




α-methyl-
magnol



240.
123-11-5
Benzaldehyde,
Anisic
0.02490000




4-methoxy-
Aldehyde



241.
57576-09-7
Cyclohexanol, 5-
Iso Pulegol
0.02480000




methyl-2-(1-
Acetate





methylethenyl)-, 1-






acetate, (1R,2S,5R)-




242.
51566-62-2
6-Octenenitrile,
Citronellyl
0.02470000




3,7-dimethyl-
Nitrite



243.
60335-71-9
2H-Pyran, 3,6-
Rosyrane
0.02470000




dihydro-4-methyl-2-phenyl-
Super



244.
30385-25-2
6-Octen-2-ol,
Dihydro-
0.02440000




2,6-dimethyl-
myrcenol



245.
101-84-8
Benzene, 1,1′-oxybis-
Diphenyl
0.02230000





Oxide



246.
136-60-7
Benzoic acid, butyl ester
Butyl Benzoate
0.02170000


247.
93939-86-7
5,8-Methano-2H-1-
Rhuboflor
0.02120000




benzopyran, 6-






ethylideneoctahydro-




248.
83926-73-2
Cyclohexanepropanol
Coranol
0.02100000




dimethyl-, α,α-




249.
125109-85-5
Benzenepropanal, β-
Florhydral
0.02070000




methyl-3-(1-methylethyl)-




250.
104-21-2
Benzenemethanol, 4-
Anisyl
0.02050000




methoxy-, 1-acetate
Acetate



251.
1365-19-1
2-Furanmethanol, 5-
Linalool
0.02050000




ethenyltetrahydro-α,α,5-
Oxide





trimethyl-




252.
137-03-1
Cyclopentanone, 2-heptyl-
Frutalone
0.02040000


253.
2563-07-7
Phenol, 2-ethoxy-4-methyl-
Ultravanil
0.02030000


254.
1128-08-1
2-Cyclopenten-1-one,
Dihydro-
0.02020000




3-methyl-2-pentyl-
jasmone



255.
7493-57-4
Benzene, [2-(1-
Acetaldehyde
0.01990000




propoxyethoxy (ethyl]-




256.
141-25-3
7-Octen-1-ol, 3,7-
Rhodinol
0.01970000




dimethyl-




257.
216970-21-7
Bicyclo[4.3.1]decane,
3-Methoxy-7,7-
0.01960000




3-methoxy-7,7-dimethyl-
dimethyl-10-





10-methylene-
methylenebicyclo






[4.3.1]decane



258.
319002-92-1
Propanoic acid, 2-(1,1-
Sclareolate ®
0.01960000




dimethylpropoxy)-,






propyl ester, (2S)-




259.
85-91-6
Benzoic acid, 2-
Dimethyl
0.01930000




(methylamino)-, methyl ester
anthranilate



260.
13828-37-0
Cyclohexanemethanol,
Mayol
0.01920000




4-(1-methylethyl)-, cis-




261.
26330-65-4
(E)-6-ethyl-3-methyloct-
Super
0.01850000




6-en-1-ol
Muguet



262.
7540-51-4
6-Octen-1-ol,
L-Citronellol
0.01830000




3,7-dimethyl-, (3S)-




263.
106-22-9
6-Octen-1-ol, 3,7-
Citronellol
0.01830000




dimethyl-




264.
543-39-5
7-Octen-2-ol, 2-
Myrcenol
0.01820000




methyl-6-methylene-




265.
7775-00-0
Benzenepropanal,
Cyclemax
0.01820000




4-(1-methylethyl)-




266.
18479-54-4
4,6-Octadien-3-ol,
Muguol
0.01800000




3,7-dimethyl-




267.
29214-60-6
Octanoic acid, 2-
Gelsone
0.01790000




acetyl-, ethyl ester




268.
1209-61-6
5-Oxatricyclo[8.2.0.04,6]
Tobacarol
0.01730000




dodecane, 4,9,12,12-






tetramethyl-




269.
57934-97-1
2-Cyclohexene-1-
Givescone
0.01710000




carboxylic acid, 2-ethyl-






6,6-dimethyl-, ethyl ester




270.
14901-07-6
3-Buten-2-one, 4-(2,6,6-
Beta-Ionone
0.01690000




trimethyl-1-cyclohexen-1-






yl)-, (3E)-




271.
64001-15-6
4,7-Methano-1H-inden-5-
Dihydro
0.01630000




ol, octahydro-, 5-acetate
Cyclacet



212.
95-41-0
2-Cyclopenten-1-one, 2-hexyl-
Iso Jasmone T
0.01600000


273.
134-20-3
Benzoic acid, 2-amino-,
Methyl
0.01580000




methyl ester
Anthranilate



274.
100-06-1
Ethanone, 1-(4-
Para Methoxy
0.01550000




methoxyphenyl)-
Acetophenone



275.
105-86-2
2,6-Octadien-1-ol, 3,7-
Geranyl
0.01540000




dimethyl-, 1-formate, (2E)-
Formate



276.
154171-77-4
Spiro[1,3-dioxolane-2,
Ysamher K ®
0.01470000




8′(5′H)-[2H-2,4a]






methanonaphthalene],






hexahydro-1′,1′,5′,5′-






tetramethyl-, (2′S,4′aS,8′aS)-






(9CI)




277.
154171-76-3
Spiro[1,3-dioxolane-2,8′
Ysamber
0.01470000




(5′H)-[2H-2,4a]






methanonaphthalene],






hexahydro-1′,1′,5′,5′-






tetramethyl-




278.
127-41-3
3-Buten-2-one, 4-
Alpha-
0.01440000




(2,6,6-trimethyl-2-
Ionone





cyclohexen-1-yl)-, (3E)-




279.
151-05-3
Benzeneethanol, α,α-
Dimeihyl
0.01390000




dimethyl-, 1-acetate
Benzyl Carbinyl






Acetate



280.
2500-83-6
4,7-Methano-1H-inden-
Flor Acetate
0.01370000




5-ol, 3a,4,5,6,7,7a-






hexahydro-, 5-acetate




281.
150-84-5
6-Octen-1-ol, 3,7-
Citronellyl
0.01370000




dimethyl-, 1-acetate
acetate



282.
30310-41-9
2H-Pyran, tetrahydro-
Pelargene
0.01350000




2-methyl-4-methylene-






6-phenyl-




283.
68845-00-1
Bicyclo[3.3.1]nonane,
Boisiris
0.01350000




2-ethoxy-2,6,6-trimethyl-






9-methylene-




284.
106-24-1
2,6-Octadien-1-ol, 3,7-
Geraniol
0.01330000




dimethyl-, (2E)-




285.
106-25-2
2,6-Octadien-1-ol, 3,7-
Nerol
0.01330000




dimethyl-, (2Z)-




286.
75975-83-6
Bicyclo[7.2.0]undec-4-ene,
Velyvenal
0.01280000




4,11,11-trimethyl-8-






methylene-, (1R,4E,9S)-




287.
19870-74-7
1H-3a,7-Methanoazulene,
Cedryl
0.01280000




octahydro-6-methoxy-
methyl ether





3,6,8,8-tetramethyl-,






(3R,3aS,6S,7R,8aS)-




288.
87-44-5
Bicyclo[7.2.0]undec-4-ene,
Caryophyllene
0.01280000




4,11,11-trimethyl-8-
Extra





methylene-, (1R,4E,9S)-




289.
54440-17-4
1H-Inden-1-one, 2,3-
Safraleine
0.01260000




dihydro-2,3,3-trimethyl-




290.
110-98-5
2-Propanol, 1,1′-oxybis-
Dipropylene
0.01250000





Glycol



291.
41890-92-0
2-Octanol, 7-methoxy-
Osyrol ®
0.01250000




3,7-dimethyl-




292.
71077-31-1
4,9-Decadienal, 4,8-
Floral Super
0.01230000




dimethyl-




293.
65-85-0
Benzoic Acid
Benzoic Acid
0.01220000


294.
61444-38-0
3-Hexenoic acid,
cis-3-hexenyl-cis-
0.01220000




(3Z)-3-hexen-1-yl
3-hexenoate





ester, (3Z)-




295.
116044-44-1
Bicyclo[2.2.1]hept-5-ene-
Herbanate
0.01210000




2-carboxylic acid, 3-(1-






methylethyl)-, ethyl ester,






(1R,2S,3S,4S)-rel-




296.
104-54-1
2-Propen-1-ol, 3-phenyl-
Cinnamic
0.01170000





Alcohol



297.
78-35-3
Propanoic acid, 2-methyl-,
Linalyl
0.01170000




1-ethenyl-1,5-dimethyl-4-
Isobutyrate





hexen-1-yl ester




298.
23495-12-7
Ethanol, 2-phenoxy-, 1-
Phenoxy Ethyl
0.01130000




propanoate
Propionate



299.
103-26-4
2-Propenoic acid, 3-
Methyl Cinnamate
0.01120000




phenyl-, methyl ester




300.
67634-14-4
Benzenepropanal, 2-
Florazon
0.01110000




ethyl-α,α-dimethyl-
(ortho-isomer)



301.
5454-19-3
Propanoic acid, decyl ester
N-Decyl
0.01100000





Propionate



302.
93-16-3
Benzene, 1,2-dimethoxy-
Methyl Iso
0.01100000




4-(1-propen-1-yl)-
Eugenol



303.
81782-77-6
3-Decen-5-ol, 4-methyl-
4-Methyl-3-
0.01070000





decen-5-ol



304.
67845-30-1
Bicyclo[2.2.2]oct-5-ene-2-
Maceal
0.01060000




carboxaldehyde, 6-methyl-






8-(1-methylethyl)-




305.
97-53-0
Phenol, 2-methoxy-4-
Eugenol
0.01040000




(2-propen-1-yl)-




306.
120-57-0
1,3-Benzodioxole-5-
Heliotropin
0.01040000




carboxaldehyde




307.
93-04-9
Naphthalene, 2-
Beta Naphthyl
0.01040000




methoxy-
Methyl Ether






Extra 99



308.
4826-62-4
2-Dodecenal
2 Dodecene-1-al
0.01020000


309.
20407-84-5
2-Dodecenal, (2E)-
Aldehyde
0.01020000





Mandarin



310.
5462-06-6
Benzenepropanal, 4-
Canthoxal
0.01020000




methoxy-α-methyl-




311.
94-60-0
1,4-Cyclohexane-
Dimethyl 1,4-
0.01020000




dicarboxylic acid,
cyclohexane-





1,4-dimethyl ester
dicarboxylate



312.
57378-68-4
2-Buten-1-one, 1-
delta-Damascone
0.01020000




(2,6,6-trimethyl-3-






cyclohexen-1-yl)-




313.
17283-81-7
2-Butanone, 4-(2,6,6-
Dihydro
0.01020000




trimethyl-1-cyclohexen-1-yl)-
Beta Ionone



314.
1885-38-7
2-Propenenitrile, 3-phenyl-,
Cinnamalva
0.01010000




(2E)




315.
103-48-0
Propanoic acid, 2-methyl-,
Phenyl Ethyl
0.00994000




2-phenylethyl ester
Iso Butyrate



316.
488-10-8
2-Cyclopenten-1-one, 3-
Cis Jasmone
0.00982000




methyl-2-(2Z)-2-penten-1-yl-




317.
7492-67-3
Acetaldehyde, 2-[(3,7-
Citronellyloxy-
0.00967000




dimethyl-6-octen-1-yl) oxy]-
acetaldehyde



318.
68683-20-5
1-Cyclohexene-1-ethanol, 4-
Iso Bergamate
0.00965000




(1-methylethyl)-formate




319.
3025-30-7
2,4-Decadienoic acid, ethyl
Ethyl 2,4-
0.00954000




ester, (2E,4Z)-
Decadienoate



320.
103-54-8
2-Propen-1-ol, 3-phenyl-,
Cinnamyl
0.00940000




1-acetate
Acetate



321.
18127-01-0
Benzenepropanal, 4-
Bourgeonal
0.00934000




(1,1-dimethylethyl)-




322.
3738-00-9
Naphtho[2,1-b]furan,
Ambrox ® or
0.00934000




dodecahydro-3a,6,6,9a-
Cetalox ® or





tetramethyl-
Synambran



323.
51519-65-4
1,4-Methanonaphthalen-
Tamisone
0.00932000




5(1H)-one, 4,4a,6,7,8,8a-






hexahydro-




324.
148-05-1
Dodecanoic acid, 12-
Dodecalactone
0.00931000




hydroxy-, λ-lactone (6CI,






7CI); 1,12-




325.
6790-58-5
(3aR,5aS,9aS,9bR)-
Ambronat ® or
0.00930000




3a,6,6,9a-tetramethyl-
Ambroxan ®





2,4,5,5a,7,8,9,9b-octahydro-






1H-benzo[e][1]benzofuran




326.
86-26-0
1,1′-Biphenyl, 2-methoxy-
Methyl
0.00928000





Diphenyl Ether



327.
68738-94-3
2-Naphthalenecarboxaldehyde,
Cyclomyral ®
0.00920000




octahydro-8,8-dimethyl




328.
2705-87-5
Cyclohexanepropanoic
Allyl
0.00925000




acid, 2-propen-1-yl ester
Cyclohexane






Propionate



329.
7011-83-8
2(3H)-Furanone, 5-
Lactojasmone ®
0.00885000




hexyldihydro-5-methyl-




330.
61792-11-8
2,6-Nonadienenitrile,
Lemonile ®
0.00884000




3,7-dimethyl-




331.
692-86-4
10-Undecenoic acid,
Ethyl
0.00882000




ethyl ester
Undecylenate



332.
103-95-7
Benzenepropanal, α-
Cymal
0.00881000




methyl-4-(1-methylethyl)-




333.
13019-22-2
9-Decen-1-ol
Rosalva
0.00879000


334.
94201-19-1
1-Oxaspiro[4.5]decan-2-
Methyl Laitone
0.00872000




one, 8-methyl-
10% TEC



335.
104-61-0
2(3H)-Furanone,
γ-Nonalactone
0.00858000




dihydro-5-pentyl-




336.
706-14-9
2(3W)-Furanone, 5-
γ-Decalactone
0.00852000




hexyldihydro-




337.
24720-09-0
2-Buten-1-one, 1-(2,6,6-
α-Damascone
0.00830000




trimethyl-2-cyclohexen-






1 yl)-, (2E)-




338.
39872-57-6
2-Buten-1-one, 1-
Isodamascone
0.00830000




(2,4,4-trimethyl-2-






cyclohexen-1-yl)-,(2E)-




339.
705-86-2
2H-Pyran-2-one,
Decalactone
0.00825000




tetrahydro- 6-pentyl-




340.
67634-15-5
Benzenepropanal,
Floralozone
0.00808000




4-ethyl-α,α-dimethyl-




341.
40527-42-2
1,3-Benzodioxole, 5-
Heliotropin
0.00796000




(diethoxymethyl)-
Diethyl Acetal



342.
56973-85-4
4-Penten-1-one, 1-
Neobutenone α
0.00763000




(5,5-dimethyl-1-






cyclohexen-1-yl)-




343.
128-51-8
Bicyclo[3.1.1]hept-2-
Nopyl
0.00751000




ene-2-ethanol-6,6-
Acetate





dimethyl-, 2-acetate




344.
103-36-6
2-Propenoic acid, 3-
Ethyl
0.00729000




phenyl-, ethyl ester
Cinnamate



345.
5182-36-5
1,3-Dioxane, 2,4,6-
Floropal ®
0.00709000




trimethyl-4-phenyl-




346.
42604-12-6
Cyclododecane,
Boisambrene
0.00686000




(methoxymethoxy)-




347.
33885-52-8
Bicycio[3.1.l]hept-2-
Pinyl Iso
0.00685000




ene-2-propanal, α,α,6,6-
Butyrate





tetramethyl-
Alpha



348.
92015-65-1
2(3H)-Benzofuranone,
Natactone
0.00680000




hexahydro-3,6-dimethyl-




349.
63767-86-2
Cyclohexanemethanol, α-
Mugetanol
0.00678000




methyl-4-(1-methylethyl)-




350.
3288-99-1
Benzeneacetonitrile, 4-
Marenil CI
0.00665000




(1,1-dimethylethyl)-




351.
35044-68-9
2-Buten-1-one, 1-(2,6,6-
beta-
0.00655000




trimethyl-1-cyclohexen-1-yl)-
Damascone



352.
41724-19-0
1,4-Methanonaphthalen-
Plicatone
0.00652000




6(2H)-one, octahydro-7-






methyl-




353.
75147-23-8
Bicyclo[3.2.1]oclan-8-one,
Buccoxime ®
0.00647000




1,5-dimethyl-, oxime




354.
25634-93-9
2-Methyl-5-phenylpentan-
Rosaphen ®
0.00637000




1-ol
600064



355.
55066-48-3
3-Methyl-5-phenylpentanol
Phenyl
0.00637000





Hexanol



356.
495-62-5
Cyclohexene, 4-(1,5-
Bisabolene
0.00630000




dimethyl-4-hexen-1-






ylidene)-1-methyl-




357.
2785-87-7
Phenol, 2-methoxy-4-propyl-
Dihydro
0.00624000





Eugenol



358.
87-19-4
Benzoic acid, 2-hydroxy-,
Iso Butyl
0.00613000




2-methylpropyl ester
Salicylate



359.
4430-31-3
2H-1-Benzopyran-2-one,
Octahydro
0.00586000




octahydro-
Coumarin



360.
38462-22-5
Cyclohexanone, 2-(1-
Ringonol
0.00585000




mercapto-1-methylethyl)-
50 TEC





5-methyl-




361.
77-83-8
2-Oxiranecarboxylic
Ethyl Methyl
0.00571000




acid, 3-methyl-3-phenyl-,
Phenyl





ethyl ester
Glycidate



362.
37677-14-8
3-Cyclohexene-1-
Iso Hexenyl
0.00565000




carboxaldehyde, 4-(4-
Cyclohexenyl





methyl-3-penten-1-yl)-
Carboxaldehyde



363.
103-60-6
Propanoic acid,
Phenoxy Ethyl
0.00562000




2-methyl-, 2-phenoxyethyl
iso-Butyrate





ester




364.
18096-62-3
Indenol[1,2-d]-1,3-dioxin,
Indoflor ®
0.00557000




4,4a,5,9b-tetrahydro-




365.
63500-71-0
2H-Pyran-4-ol, tetrahydro-
Florosa Q/
0.00557000




4-methyl-2-(2-methylpropyl)-
Florol



366.
65405-84-7
Cyclohexanebutanal,
Cetonal ®
0.00533000




α,2,6,6-tetramethyl-




367.
171102-41-3
4,7-Methano-1H-inden-6-ol,
Flor Acetate
0.00530000




3a,4,5,6,7,7a-hexahydro-8,8-






dimethyl-, 6-acetate




368.
10339-55-6
1,6-Nonadien-3-ol, 3,7-
Ethyl linalool
0.00520000




dimethyl-




369.
23267-57-4
3-Buten-2-one, 4-(2,2,6-
Ionone
0.00520000




trimethyl-7-oxabicyclo[4.1.0]
Epoxide Beta





hept-1-yl)-




370.
97-54-1
Phenol, 2-methoxy-4-(1-
Isoeugenol
0.00519000




propen-1-yl)-




371.
67663-01-8
2(3H)-Furanone, 5-
Peacholide
0.00512000




hexyldihydro-4-methyl-




372.
33885-52-8
Bicyclo[3.1.1]hept-2-ene-2-
Pinyl Iso
0.00512000




propanal, α,α,6,6-tetramethyl-
Butyrate






Alpha



373.
23696-85-7
2-Buten-1-one, 1-(2,6,6-
Damascenone
0.00503000




trimethyl-1,3-cyclohexadien-






1-yl)-




374.
80-71-7
2-Cyclopenten-1-one, 2-
Maple
0.00484000




hydroxy-3-methyl-
Lactone



375.
67662-96-8
Propanoic acid, 2,2-dimethyl-,
Pivarose Q
0.00484000




2-phenylethyl ester




376.
2437-25-4
Dodecanenitrile
Clonal
0.00480000


377.
141-14-0
6-Octen-1-ol, 3,7-dimethyl-,
Citronellyl
0.00469000




1-propanoate
Propionate



378.
54992-90-4
3-Buten-2-one, 4-
Myrrhone
0.00460000




(2,2,3,6-tetramethylcyclohexyl)-




379.
55066-49-4
Benzenepentanal, β-methyl-
Mefranal
0.00455000


380.
7493-74-5
Acetic acid, 2-phenoxy-,
Allyl Phenoxy
0.00454000




2-propen-1-yl ester
Acetate



381.
80-54-6
Benzenepropanal, 4-(1,1-
Lilial ®
0.00444000




dimethylethyl)-α-methyl-




382.
86803-90-9
4,7-Methano-1H-indene-2-
Scenlenal ®
0.00439000




carboxaldehyde, octahydro-






5-methoxy-




383.
68991-97-9
2-Naphthalenecarboxaldehyde,
Melafleur
0.00436000




1,2,3,4,5,6,7,8-octahydro-8,8-






dimethyl-




384.
18871-14-2
Pentitol, 1,5-anhydro-2,4-
Jasmal
0.00434000




dideoxy-2-pentyl-, 3-acetate




385.
58567-11-6
Cyclododecane,
Boisambren
0.00433000




(ethoxymethoxy)-
Forte



386.
94400-98-3
Naphth[2,3-b]oxirene,
Molaxone
0.00425000




1a,2,3,4,5,6,7,7a-octahydro-






1a,3,3,4,6,6-hexamethyl-,






(1aR,4S,7aS)-rel-




387.
79-69-6
3-Buten-2-one, 4-(2,5,6,6-
alpha-Irone
0.00419000




tetramethyl-2-cyclohexen-1-yl)-




388.
65442-31-1
Quinoline, 6-(1-methylpropyl)-
Iso Butyl
0.00408000





Quinoline



389.
87731-18-8
Carbonic acid, 4-cycloocten-
Violiff
0.00401000




1-yl methyl ester




390.
173445-65-3
1H-Indene-5-propanal,
Hivernal
0.00392000




2,3-dihydro-3,3-dimethyl-
(A-isomer)



391.
23911-56-0
Ethanone, 1-(3-methyl-2-
Nerolione
0.00383000




benzofuranyl)-




392.
52474-60-9
3-Cyclohexene-1-
Precyclemone
0.00381000




carboxaldehyde, 1-methyl-
B





3-(4-methyl-3-penten-1-yl)




393.
139539-66-5
6-Oxabicyclo[3.2.1]octane,
Cassifix
0.00381000




5-methyl-1-(2,2,3-trimethyl-






3-cyclopenlen-1-yl)-




394.
80858-47-5
Benzene, [2-
Phenafleur
0.00380000




(cyclohexyloxy)ethyl]-




395.
32764-98-0
2H-Pyran-2-one,
Jasmolactone
0.00355000




tetrahydro-6-(3-penten-1-yl)-




396.
78417-28-4
2,4,7-Decatrienoic
Ethyl 2,4,7-
0.00353000




acid, ethyl ester
decatrienoate



397.
140-26-1
Butanoic acid, 3-
Beta Phenyl
0.00347000




methyl-, 2-phenylethyl ester
Ethyl






Isovalerate



398.
105-90-8
2,6-Octadien-1-ol, 3,7-
Geranyl
0.003360000




dimethyl-, 1-propanoate, (2E)-
Propionate



399.
41816-03-9
Spiro[1,4-methanonaphthalene-
Rhubofix ®
0.00332000




2(1H),2′-oxirane], 3,4,4a,5,8,8a-






hexahydro-3′,7-dimethyl-




400.
7070-15-7
Ethanol, 2-[[(1R,2R,4R)-
Arbanol
0.00326000




1,7,7-trimethylbicyclo[2.2.1]






hept-2-yl]oxy]-, rel-




401.
93-29-8
Phenol, 2-methoxy-4-(1-
Iso Eugenol
0.00324000




propen-1-yl)-, 1-acetate
Acetate



402.
476332-65-7
2H-Indeno[4,5-b]furan,
Amber Xtreme
0.00323000




decahydro-2,2,6,6,7,8,8-
Compound 1





heptamethyl-




403.
68901-15-5
Acetic acid, 2-(cyclohexyloxy)-,
Cyclogalbanate
0.00323000




2-propen-1-yl ester




404.
107-75-5
Octanal, 7-hydroxy-3,7-
Hydroxy-
0.00318000




dimethyl-
citronellal



405.
68611-23-4
Naphtho[2,1-b]furan, 9b-
Grisalva
0.00305000




ethyldodecahydro-






3a,7,7-trimethyl-




406.
313973-37-4
1,6-Heptadien-3-one,
Pharaone
0.00298000




2-cyclohexyl-




407.
137-00-8
5-Thiazoleethanol, 4-methyl-
Sulfurol
0.00297000


408.
7779-30-8
1-Penten-3-one, 1-(2,6,6-
Methyl Ionone
0.00286000




trimethyl-2-cyclohexen-1-yl)-




409.
127-51-5
3-Buten-2-one, 3-methyl-4-
Isoraldeine
0.00282000




(2,6,6-trimethyl-2-
Pure





cyclohexen-1-yl)-




410.
72903-27-6
1,4-Cyclohexane-
Fructalate ™
0.00274000




dicarboxylic acid,






1,4-diethyl ester




411.
7388-22-9
3-Buten-2-one, 4-(2,2-
Ionone
0.00272000




dimethyl-6-
Gamma





methylenecyclohexyl)-






3-methyl-
Methyl



412.
104-67-6
2(3H)-Furanone,
gamma-
0.00271000




5-heptyldihydro-
Undecalactone






(racemic)



413.
1205-17-0
1,3-Benzodioxole-5-propanal,
Helional
0.00270000




α-methyl-




414.
33704-61-9
4H-Inden-4-one, 1,2,3,5,6,7-
Cashmeran
0.00269000




hexahydro-1,1,2,3,3-pentamethyl-




415.
36306-87-3
Cyclohexanone, 4-(1-
Kephalis
0.00269000




ethoxyethenyl)-3,3,5,5-tetramethyl-




416.
97384-48-0
Benzenepropanenitrile, α-
Citrowanil ®
0.00265000




ethenyl-α-methyl-
B



417.
141-13-9
9-Undecenal, 2,6,10-trimelhyl-
Adoxal
0.00257000


418.
2110-18-1
Pyridine, 2-(3-phenylpropyl)-
Corps
0.00257000





Racine VS



419.
27606-09-3
Indeno[1,2-d]-1,3-dioxin,
Magnolan
0.00251000




4,4a,5,9b-tetrahydro-2,4-dimethyl-




420.
67634-20-2
Propanoic acid. 2-methyl-,
Cyclabute
0.00244000




3a,4,5,6,7,7a-hexahydro-4,7-






methano-1H-inden-5-yl ester




421.
65405-72-3
1-Naphthalenol, 1,2,3,4,4a,7,8,8a-
Oxyoctaline
0.00236000




octahydro-2,4a,5,8a-tetramethyl-,
Formate





1-formate




422.
122-40-7
Heptanal, 2-(phenylmethylene)-
Amyl Cinnamic
0.00233000





Aldehyde



423.
103694-68-4
Benzenepropanol, β,β,3-trimethyl-
Majantol ®
0.00224000


424.
13215-88-8
2-Cyclohexen-1-one, 4-(2-buten-
Tabanone
0.00223000




1-ylidene)-3,5,5-trimethyl-
Coeur



425.
25152-85-6
3-Hexen-1-ol, 1-benzoate, (3Z)-
Cis-3-Hexenyl
0.00203000





Benzoate



426.
406488-30-0
2-Ethyl-N-methyl-N-(m-
Paradisamide
0.00200000




tolyl)butanamide




427.
121-33-5
Benzaldehyde, 4-hydroxy-3-
Vanillin
0.00194000




methoxy-




428.
77-54-3
1H-3a,7-Methanoazulen-6-ol,
Cedac
0.00192000




octahydro-3,6,8,8-tetramethyl-,






6-acetate, (3R,3aS,6R,7R,8aS)-




429.
76842-49-4
4,7-Methano-1H-inden-6-ol,
Frutene
0.00184000




3a,4,5,6,7,7a-hexahydro-8,8-






dimethyl-, 6-propanoate




430.
121-39-1
2-Oxiranecarboxylic
Ethyl Phenyl
0.00184000




acid, 3-phenyl-, ethyl ester
Glycidale



431.
211299-54-6
4H-4a,9-Methanoazuleno[5,6-d]-
Ambrocenide ®
0.00182000




1,3-dioxole, octahydro-






2,2,5,8,8,9a-hexamethyl-,






(4aR,5R,7aS,9R)-




432.
285977-85-7
(2,5-Dimethyl-1,3-dihydroinden-
Lilyflore
0.00180000




2-yl)methanol




433.
10094-34-5
Butanoic acid, 1,1-dimethyl-2-
Dimethyl
0.00168000




phenylethyl ester
Benzyl






Carbinyl






Bulyrate



434.
40785-62-4
Cyclododeca[c]furan,
Muscogene
0.00163000




1,3,3a,4,5,6,7,8,9,10,11,13a-






dodecahydro-




435.
75490-39-0
Benzenebutanenitrile, α,α,γ-
Khusinil
0.00162000




trimethyl-




436.
55418-52-5
2-Butanone, 4-(1,3-benzodioxol-
Dulcinyl
0.00161000




5-yl)-




437.
3943-74-6
Benzoic acid, 4-hydroxy-3-
Carnaline
0.00157000




methoxy-, methyl ester




438.
72089-08-8
3-Cyclopentene-1-butanol,
Brahmanol ®
0.00154000




β,2,2,3-tetramethyl-2-






Methyl-4-(2,2,3-trimethyl-3-






cyclopenten-1-yl)butanol




439.
3155-71-3
2-Butenal, 2-methyl-4-(2,6,6-
Boronal
0.00147000




trimethyl-1-cyclohexen-1-yl)-




440.
2050-08-0
Benzoic acid, 2-hydroxy-,
Amyl
0.00144000




pentyl ester
Salicylate



441.
41199-20-6
2-Naphthalenol, decahydro-
Ambrinol
0.00140000




2,5,5-trimethyl-




442.
12262-03-2
ndecanoic acid, 3-
Iso Amyl
0.00140000




methylbutyl ester
Undecylenate



443.
107-74-4
1,7-Octanediol, 3,7-dimethyl-
Hydroxyol
0.00139000


444.
91-64-5
2H-1-Benzopyran-2-one
Coumarin
0.00130000


445.
68901-32-6
1,3-Dioxolane. 2-[6-methyl-8-
Glycolierral
0.00121000




(1-methylethyl) bicyclo[2.2.2]






oct-5-en-2-yl]-




446.
68039-44-1
Propanoic acid, 2,2-dimethyl-,
Pivacyclene
0.00119000




3a,4,5,6,7,7a-hexahydro-4,7-






methano-1H-inden-6-yl ester




447.
106-29-6
Butanoic acid, (2E)-3,7-
Geranyl
0.00116000




dimethyl-2,6-octadien-1-yl ester
Butyrate



448.
5471-51-2
2-Butanone, 4-(4-hydroxyphenyl)-
Raspberry
0.00106000





ketone



449.
109-42-2
10-Undecenoic acid, butyl ester
Butyl
0.00104000





Undecylenate





*Vapor Pressures are acquired as described in the Test Methods Section.


**Origin: Same as tor Table 2 hereinabove.






Test Methods

The following assays set forth must be used in order that the invention described and claimed herein may be more fully understood.


Test Method 1: Determining Vapor Pressure

In order to determine the vapor pressure for the fragrance materials, go to the website https://scifinder.cas.org/scifinder/view/scifinder/scifinderExplore.jsf and follow these steps to acquire the vapor pressure.


1. Input the CAS registry number for the particular fragrance material.


2. Select the vapor pressure from the search results.


3. Record the vapor pressure (given in Torr at 25° C.).


SciFinder uses Advanced Chemistry Development (ACD/Labs) Software Version 14.02). If the CAS number for the particular fragrance material is unknown or does not exist, you can utilize the ACD/Labs reference program to directly determine the vapor pressure. Vapor Pressure is expressed in 1 Torr, which is equal to 0.133 kilopascal (kPa).


Test Method 2: Olfactory Tests

In order to show the effect of the substantially non-odorous fragrance fixatives on the perception of fragrance profile in a composition of the present invention, test compositions are made, as described in the Example section, and given to panelists to evaluate.


At the testing facility, 50 μL samples of the compositions and the controls are applied to glass slides and placed on a hot plate at 32° C. to represent skin temperature for varying durations. It is important that glass slides of samples that are to be later compared are prepared at the same time. The panelists are asked to evaluate the perceived fragrance profile (intensity and/or character) of each glass slide sample at a given time-point. Slides are presented coded so that their identity is not known by the panelists. Within a given time point panelists evaluate the slides in a random order and are able to revisit their assessment as they work through the slides at that time point. Their assessments are recorded. In the subsequent analysis, the data for strength and character comparisons are drawn from the independent assessments carried out at a given time point. Only when using the difference scale below are any two products physically directly compared to each other. Panelists are selected from individuals who are either trained to evaluate fragrances according to the scales below or who have experience with fragrance evaluation in the industry. Typically, around 6 to 10 panelists are used to evaluate a given product and its control.


(a) Fragrance Intensity:


The panelists are asked to give a score on a scale of 0 to 5 for perceived fragrance intensity according to the odour intensity scale set out in Table 4 herein below.









TABLE 4







Odour Intensity Scale










Score
Fragrance Intensity







0
None



1
Very Weak



2
Weak



3
Moderate



4
Strong



5
Very Strong










(b) Fragrance Character:


The panelists are asked to assess the fragrance character in one of 2 ways:

    • i) a score on a scale of 0 to 3 for the dominance of particular characters that are relevant to that particular fragrance, e.g.: fresh, green, watery, floral, rose, muguet, fruity, apple, berry, citrus, creamy, woody, balsamic, amber, musk just to name a few, according to the odour grading scale set out in Table 5(i) herein below;
    • ii) a score on a scale of 1 to 5 for changes in the perceived fragrance profile change for the test compositions versus the controls according to the odour grading scale set out in Table 5(ii) herein below.









TABLE 5(i)







Character Dominance Odour Grading Scale








Score
Fragrance Character Dominance





0
Not noticeable


1
Slight presence of the character


2
Moderate presence of the character


3
Dominance of the character
















TABLE 5(ii)







Character Difference Odour Grading Scale








Score
Fragrance Character Change





1
Fragrance character is unchanged, i.e., no difference between the



sample vs. the control.


2
Slight fragrance character change when compared directly with



the control.


3
Moderate fragrance change but similar character to the control.


4
Large difference in fragrance character from the control.


5
Total difference in the fragrance character from the control.









The results of the panelists are averaged and then analysed using Analysis of Variance methods. The model treats the subject as a random effect and looks at the impact of product, time and the interaction between product and time. From the analysis the least square means for the product and time interaction are obtained. These means (as well as their confidence intervals) are then plotted to enable comparisons between products at each time point. It should be noted that the confidence levels plotted are intended as a guide, and not as a statistical comparison, as they do not take into account that multiple testing has been performed. As well as a graphical assessment, statistical comparisons between the two products at each of the time points are performed with a Tukey correction for multiple comparisons. The p-values for the product differences were obtained, with p-values<0.05 indicating a statistical difference between the two products at 5% significance (or 95% confidence).


Test Method 3: Analytical Evaporation Tests

The following test is carried out to demonstrate the improved or enhanced longevity of a fragrance profile of a composition of the present invention vs. a control. In particular, the test measures the effect of a substantially non-odorous fragrance fixative on the evaporation rate of one or more fragrance materials (e.g., 10 PRMs) formulated in a composition. The evaporation response of the fragrance materials to the fixative, as a function of time, is measured through the use of gas chromatography (“GC”).

    • 1. A test composition may comprise a substantially non-odorous fragrance fixative (as disclosed in Table 1) with either: (i) a fragrance material (any one of the fragrance materials disclosed in Table 3) or (ii) a blend of fragrance materials from Table 3 (as disclosed as Fragrance Example 6 in Table 11). The test composition may also comprise high purity ethanol, such as Hayman 100% EP/BP grade, and (optionally) deionised water. Sample test compositions are provided in Tables 18(d), 19(b) and 19(c). All of the ingredients are admixed until evenly distributed in the test compositions.
    • 2. A control composition to the test composition described in 1 above, without the substantially non-odorous fragrance fixative, is made in a similar manner to Step 1, except that the missing substantially non-odorous fragrance fixative is replaced by deionized water. Sample control compositions are provided in Tables 18(d), 19(b) and 19(c).
    • 3. An internal standard is needed to correct for variations of the amount of composition dispensed in the evaporation test as well as loss during the GC analysis. The internal standard has a vapor pressure of less than 0.001 Torr (0.000133 kPa) at 25° C. and is soluble in the composition or fragrance material. A suitable non-limiting example of internal standard is triethyl citrate. The internal standard and fragrance material are admixed until evenly distributed at a level of 90 to 95 parts by weight of fragrance material and the required amount of internal standard to reach 100 parts. This mixture is then use to prepare the sample compositions in Step 1 and 2. Alternatively, the internal standard and test or control composition are admixed until evenly distributed at a level of 99 to 99.75 parts by weight of composition and the required amount of internal standard to reach 100 parts. This resultant solution is used in subsequent steps.
    • 4. A hotplate is set to a temperature of 32° C. An aluminium container, such as TA instrument Tzero™ pan is placed on the hotplate. 20 μL of the test or control composition is introduced in the aluminium container using a micropipette. Alternatively, the aluminium container may be filled with the test or control composition to its full capacity. The time at which this takes place is determined to be time zero (i.e., T=0). Multiple aluminium containers are prepared and left at the set temperature for pre-determined periods of time, such as for example 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, 6 hrs, 8 hrs and up to 12 hrs.
    • 5. The aluminium container is removed from the hotplate at the end of the pre-determined time period and its content transferred into a 4 mL glass vial already containing 2 mL of highly volatile solvent, such as high purity ethanol or hexane.
    • 6. The glass vial is mixed using a Heidolph multi REAX shaker, or equivalent, for 5 to 10 mins to extract the fragrance materials into the solvent phase. 1.5 mL of the resultant solution is transferred to a 2 mL GC vial.
    • 7. The GC vial is analysed on an Agilent GC system 6890 equipped with an autosampler, or equivalent. A GC column such as a DB-5MS, Rxi-5 SilMS model, with a length of 30 m, an inner diameter of 0.25 mm and a film thickness of 1 μm is used. The GC parameters are set to the values indicated as follows:









TABLE 5(iii)





GC Parameters
















Injector temperature:
270° C.


Initial gas velocity:
30 to 40 cm/sec (for Helium as the carrier



gas)


Injection type:
Split


Initial oven temperature:
 50° C. for 1 min


Temperature ramp:
 8° C./min


Final oven temperature:
310° C.













      • Gas chromatography with flame ionisation detection (“FID”) or with mass spectrometry (“MS”) can be used for the identification and quantification of aroma chemicals in the compositions. Either detection system can be used in conjunction with GC. The column dimensions as well as GC settings described in this method, such as injector temperature, carrier gas velocity, temperature ramp and final oven temperature can be adjusted to optimize the response of the fragrance material and internal standard being monitored. The detection system settings, such as FID gas flows and temperature or MS parameters, should be optimized by a trained analyst to enable the precise detection and quantification of the analytes of interest.



    • 8. The peak area of the fragrance material and internal standard are recorded. The peak area ratio of the fragrance material and the internal standard is calculated at each time point for each sample composition. The % loss of non-evaporated fragrance material remaining from T=0 is calculated at each time point for each sample composition. The % of non-evaporated fragrance material from T=0 calculated. The % fragrance material remaining in each composition is plotted to give an evaporation profile over time. This is done for both the test and control compositions. Significance is determined by comparison of the evaporation profile for the same fragrance material or same fragrance mixture in the test and control compositions.





Test Method 4: Analytical Headspace Tests

The following test is carried out to demonstrate the character retention over time of a fragrance composition of the present invention vs. a control. It is necessary for the test and control samples to be run at approximately the same time to ensure that ambient conditions are the same. The test measures the presence of one or more fragrance materials in the headspace formed in a sealed vial by the test composition, after set evaporation times. The fragrance profile in the headspace is measured at specific time points through the use of headspace (“HS”) gas chromatography (“GC”).

    • 1. The test and control compositions as described in the Example section are used for the evaluation.
    • 2. Capillaries of about 2 cm to 3.5 cm, with one sealed end are cut from a Sigma Aldrich “Stuart™ melting point tube” product code Z673269, or equivalent. A suitable fixed volume chosen between 50 and 200 μL of the composition is pipetted into the well of a WVR Tissue Culture 96 F well plate, or equivalent. The sealed end of the glass capillary is dipped into the filled well and left for at least 15 secs to wet the surface of the glass. Care must be taken not to contact the glass capillary with the sides of the well by maintaining it straight and approximately in the center of the well.
    • 3. The glass capillary is then removed from the well and inverted or transferred onto a stable surface or into a holder and allowed to evaporate at ambient conditions for a set period of time. A windshield may be used to reduce high air turbulence.
    • 4. The glass capillary is then introduced into an empty 20 mL HS vial, which is immediately closed with a PTFE cap. The time at which this takes place is determined to be time T=initial (i.e., T=10 mins)
    • 5. Multiple glass capillaries are prepared in the same way and left to evaporate at ambient temperature for pre-determined periods of time, such as for example 10, 15, 30 mins, 1 hr, 2 hrs, 3 hrs, 4 hrs, 5 hrs, and up to 6 hrs, before being introduced to the headspace vial and sealed.
    • 6. The HS vial is then analysed on an Agilent GC system 6890 equipped with a Gerstel MPS 2 autosampler, or equivalent, capable of performing SPME injections. A SPME fiber assembly DVB/CAR/PDMS (50/30 μm, 1 cm length) is required. A GC column such as a DB-5MS, ZB-SMSi models, or equivalent phase, with a length of 30 m, an inner diameter of 0.25 mm and a film thickness of 1 μm is used.
    • 7. The SPME HS parameters are set to the values indicated as follows:









TABLE 5(iv)





SPME Parameters


















Incubation chamber temperature:
 40° C.



Incubation time:
 20 mins



Agitation of sample
250 RPM



Extraction time
 5 mins



Desorption time
 2 mins












    • 8. The GC parameters are set to the values indicated as follows:












TABLE 5(v)





GC Parameters
















Injector temperature:
270° C.


Initial gas velocity:
20 to 40 cm/sec (for Helium as the carrier



gas)


Initial oven temperature:
 45° C. with 2 mins Hold Time


Temperature ramp 1:
 30° C./min


Temperature 1:
 80° C.


Temperature ramp 2:
 8° C./min


Final temperature:
300° C.













      • Gas chromatography with flame ionization detection (“FID”) or with mass spectrometry (“MS”) can be used for the identification and quantification of fragrance material in the compositions. Either detection system can be used in conjunction with GC. The column dimensions as well as GC settings described in this method, such as injector temperature, carrier gas velocity, temperature ramp and final oven temperature can be adjusted to optimize the response of the fragrance material being monitored. The detection system settings, such as FID gas flows and temperature or MS parameters, should be optimized by a trained analyst to enable the precise detection and identification of the analytes of interest.



    • 9. A qualitative assessment of the chromatograms obtained is performed by comparing the peak height of the fragrance materials and overall chromatogram at time T=10 mins to other time points. A dotted line is drawn around an estimated retention time where fragrance materials with a vapour pressure of 0.001 Torr or less (0.000133 kPa or less) elute during the analysis. The difference between the peaks present at each measured time point for the test and control compositions provides evidence of the retention of the character of the fragrance over time.

    • 10. This test set-up is designed to enable the collection of the headspace in a manner that does not saturate the SPME fiber. If the fiber is saturated it does not provide an accurate analysis of the headspace composition. Therefore the quantity of liquid and the evaporation surface area are very different from those in the olfactive evaluation of the same samples. For this reason it is not possible to compare directly the evaporation time frames used in the 2 experiments. It is expected that the evaporation profile is much faster in this headspace experiments compared to the olfactive evaluations.





EXAMPLES

The following examples are provided to further illustrate the present invention and are not to be construed as limitations of the present invention, as many variations of the present invention are possible without departing from its spirit or scope.


Example 1
Fragrance Oils

Fragrance examples 1, 2, 3, 4b and 5b are provided below in Tables 6, 7, 8, 9 and 10, respectively, as non-limiting examples of formulations of fragrance materials intended to form the fragrance component of the compositions of the present invention. The exemplary formulations of the fragrance materials span the range from “simple accords” (less than 10 fragrance materials) to “complex fragrances” (greater than 30 fragrance materials). Typically, full bodied fragrance compositions do not comprise less than about 30 fragrance materials.


Fragrance examples 4a and 5a provided in Table 9 and 10, respectively, below are examples of traditional formulations of fragrance materials that fall outside the scope of the present invention.


Fragrance example 6 provided in Table 11 below as an example of a formulation of volatile fragrance materials.


Fragrance examples 7 and 8 are provided in Tables 12 and 13 below as examples of a formulation of fragrance materials intended to form the fragrance component that fall outside the scope of the present invention.


Fragrance examples 9 to 16 are provided in Tables 14 and 15 below as examples of formulations of fragrance materials containing higher than 30 wt % of the low volatile fragrance materials.


Fragrance examples 17 and 18 are provided in Tables 16 and 17 below as comparative samples of formulations of fragrance materials intended to form the fragrance component.









TABLE 6







Fragrance Example 1 (Fresh Floral Accord - 10 wt % of Low Volatile


Fragrance Materials)












Vapor Pressure
Parts


Ingredients
CAS Number
(Torr at 25° C.)
(wt %)













Benzyl acetate
140-11-4
0.1640
10.8


Linalool
78-70-6
0.0905
9.8


Phenethyl alcohol
60-12-8
0.0741
15.7


Indole
120-72-9
0.0298
1.0


α-Terpineol
98-55-5
0.0283
2.9


Geranyl acetate
105-87-3
0.0256
4.9


Cymal
103-95-7
0.00881
5.9


Hydroxycitronellal
107-75-5
0.00318
22.4


Majantol
103694-68-4
0.00224
16.6


Hexyl cinnamic
101-86-0
0.000697
10.0


aldehyde











Total
100.00
















TABLE 7







Fragrance Example 2 (Fresh Male Accord - 13.51 wt % of Low Volatile


Fragrance Materials)












Vapor Pressure
Parts


Ingredients
CAS Number
(Torr at 25° C.)
(wt %)













d-Limonene
5989-27-5
1.540000
10.0


Dihydromyrcenol
18479-58-8
0.166000
10.0


Boisiris
68845-00-1
0.013500
6.5


Canthoxal
5462-06-6
0.010200
8.0


Helional
1205-17-0
0.002700
10.0


Kephalis
36306-87-3
0.002690
20.0


Majantol
103694-68-4
0.002240
15.5


Javanol ®
198404-98-7
0.000902
5.0


Galaxolide ®*
1222-05-5
0.000414
7.5


Isopropyl
110-27-0

7.5


Myristate











Total
100.00





*Supplied at 50% in Isopropyl myristate.













TABLE 8







Fragrance Example 3 (Sweet Dream 18 Fragrance - 11.15 wt % of


Low Volatile Fragrance Materials)












Vapor Pressure
Parts


Ingredients
CAS Number
(Torr at 25° C.)
(wt %)













Prenyl acetate
1191-16-8
3.99000000
0.100


Manzanate
39255-32-8
2.91000000
0.200


Hexyl acetate
142-92-7
1.39000000
0.700


cis-3-Hexenyl
3681-71-8
1.22000000
0.200


acetate





Benzaldehyde
100-52-7
0.97400000
0.200


Liffarome
67633-96-9
0.72100000
0.150


Hexyl isobutyrate
2349-07-7
0.41300000
0.055


Dihydromyrcenol
18479-58-8
0.16600000
2.500


Benzyl acetate
140-11-4
0.16400000
0.700


Linalyl acetate
115-95-7
0.11600000
2.500


Verdox
88-41-5
0.10300000
4.000


Phenethyl alcohol
60-12-8
0.07410000
8.000


Rossitol
215231-33-7
0.02990000
1.500


alpha-Terpineol
98-55-5
0.02830000
1.500


Geranyl acetate
105-87-3
0.02560000
1.500


Rhodinol
141-25-3
0.01970000
0.700


Givescone
57934-97-1
0.01710000
0.700


Methyl anthranilate
134-20-3
0.01580000
0.050


Ysamber K
154171-77-4
0.01470000
1.000


alpha-Ionone
127-41-3
0.01440000
3.000


Citronellyl acetate
150-84-5
0.01370000
0.500


cis-3-hexenyl-cis-3-
61444-38-0
0.01220000
0.200


hexenoate





Cinnamic alcohol
104-54-1
0.01170000
0.100


delta-damascone
57378-68-4
0.01020000
0.200


Citronellyloxyacetal
7492-67-3
0.00967000
0.100


dehyde





Cymal
103-95-7
0.00881000
0.500


Floralozone
67634-15-5
0.00808000
0.100


Ethylmethylphenylg
77-83-8
0.00571000
0.200


lycidate





Florosa Q
63500-71-0
0.00557000
3.000


Ethyl linalool
10339-55-6
0.00520000
6.400


Pivarose
67662-96-8
0.00484000
2.500


Hydroxycitronellal
107-75-5
0.00318000
7.500


Methyl Ionone
7779-30-8
0.00286000
4.000


gamma-
104-67-6
0.00271000
0.500


Undecalactone





Kephalis
36306-87-3
0.00269000
5.000


Cashmeran
33704-61-9
0.00269000
1.000


Magnolan
27606-09-3
0.00251000
3.000


Majantol
103694-68-4
0.00224000
6.900


Brahmanol
72089-08-8
0.00154000
3.000


Coumarin
91-64-5
0.00130000
0.500


Glycolierral
68901-32-6
0.00121000
0.100


Raspberry ketone
5471-51-2
0.00106000
0.100


Top Mango base 3


0.500


Cherry base 3


0.200


Cassis base 3


0.300


Bergamot Oil 4


6.000


Prunella base 3


0.500


Hexyl cinnamic
101-86-0
0.00069700
1.500


aldehyde





Sandalore
65113-99-7
0.00062500
3.000


Dupical
30168-23-1
0.00044100
0.005


Galaxolide ®1
1222-05-5
0.00041400
1.500


Ebanol
67801-20-1
0.00028100
2.000


Helvetolide
141773-73-1
0.00005790
2.000


Warm Milk base 5


0.200


Vanilla Absolute 2, 6


0.100


Isopropyl Myristate


1.500


Dipropylene Glycol


6.040




Total
100.00






1Supplied at 50% in IPM.




2 Supplied at 50% in DiPG.




3 Proprietary bases that contain a mixture of perfume raw materials, judged to be of high volatility for the purposes of calculating % of low volatility PRMs.




4 Natural oils or extracts that contain a mixture of perfume raw materials, judged to be of high volatility for the purposes of calculating % of low volatility PRMs.




5 Proprietary bases that contain a mixture of perfume raw materials, judged to be of low volatility for the purposes of calculating % of low volatility PRMs.




6 Natural oils or extracts that contain a mixture of perfume raw materials, judged to be of low volatility for the purposes of calculating % of low volatility PRMs.














TABLE 9







Fragrance Examples 4a and 4b (″Traditional Floral Magnifica″ Example 4a -


37 wt % of Low Volatile Fragrance Materials and ″Reduced Low Volatile Floral Magnifica″


Example 4b - 13 wt % of Low Volatile Fragrance Materials)













Parts (wt %)















Example 4b



CAS
Vapor Pressure
Example 4a
(Reduced


Ingredients
Number
(Torr at 25° C.)
(Traditional)
Low Volatile)














Beta Gamma Hexenol
928-96-1
2.126000
0.20
0.20


Cis 3 Hexenyl Acetate
3681-71-8
1.219000
0.30
0.30


Benzyl Acetate
140-11-4
0.16400000
3.01
3.01


Liffarome
67633-96-9
0.721000
0.20
0.20


Ligustral Or Triplal
68039-49-6
0.578000
0.10
0.10


Methyl Pamplemousse
67674-46-8
0.214000
0.40
0.40


d-Limonene
5989-27-5
1.54000000
3.01
3.01


Phenyl Acetaldehyde 1
122-78-1
0.368000
0.0002
0.0002


Precyclemone B
52475-86-2
0.003810
0.20
0.20


Ethyl 2 4-
3025-30-7
0.009540
0.20
0.20


Decadienoate






Ambronat
6790-58-5
0.009340
2.00
2.01


Alpha Damascone
24720-09-0
0.008300
0.04
0.06


Citronellol
106-22-9
0.032900
4.01
4.01


Cyclemax
7775-00-0
0.018200
0.40
0.40


Cyclo Galbanate
68901-15-5
0.003230
0.10
0.10


Cymal
103-95-7
0.008810
0.90
1.51


Dimethyl Benzyl
10094-34-5
0.001680
0.50
0.50


Carbinyl Butyrate






Ethyl Linalool
10339-55-6
0.005200
7.23
12.04


Florol
63500-71-0
0.005570
6.43
10.71


Gamma Decalactone
706-14-9
0.008520
0.20
0.20


Geraniol
106-24-1
0.013300
3.01
5.02


Geranyl Acetate
105-87-3
0.009760
2.01
2.01


Helional
1205-17-0
0.002700
2.41
4.01


Heliotropin
120-57-0
0.010400
0.20
0.20


Hivernal
173445-65-3
0.00392000
0.20
0.20


Hydroxycitronellal
107-75-5
0.003180
2.41
4.01


Ionone Beta
14901-07-6
0.003080
0.24
0.40


Ionone Gamma
127-51-5
0.002820
1.81
3.01


Methyl






Jasmal
18871-14-2
0.004340
5.02
5.02


Jasmolactone
32764-98-0
0.003550
0.20
0.20


Linalyl Propionate
144-39-8
0.026300
1.20
1.20


Magnolan 690304
27606-09-3
0.002510
3.01
5.02


Majantol
103694-68-4
0.002240
2.41
4.01


Phenyl Ethyl Alcohol
60-12-8
0.074100
3.01
5.02


Phenyl Hexanol
55066-48-3
0.006370
3.61
6.02


Undecavertol
81782-77-6
0.010700
2.01
2.01


Vanillin
121-33-5
0.001940
0.10
0.10


cis-3-Hexenyl cis-3-
61444-38-0
0.012200
0.10
0.10


Hexenoate






Phenoxy Ethyl Iso
103-60-6
0.005620
0.50
0.50


Butyrate






5-Cyclohexadecen-1-
37609-25-9
0.000033
1.00
1.00


One






Ambrettolide
28645-51-4
0.000001
1.00
1.00


Cis-3-Hexenyl
65405-77-8
0.000246
1.51
0.50


Salicylate






Delta Muscenone
63314-79-4
0.000165
1.00
1.00


962191






Hedione ® HC
24851-98-7
0.000710
10.54
3.51


Iso-E Super ®
54464-57-2
0.000538
10.54
3.51


Para Hydroxy Phenyl
5471-51-2
0.001060
0.20
0.20


Butanone






Polysantol
107898-54-4
0.000117
0.50
0.50









Total
100
100
















TABLE 10







Fragrance Examples 5a and 5b (″Traditional Muguesia Magnifica″ Example


5a - 37 wt % of Low Volatile Fragrance Materials and ″Reduced Low Volatile Muguesia


Magnifica″ Example 5b - 13 wt % of Low Volatile Fragrance Materials)













Parts (wt %)















Example 5b



CAS
Vapor Pressure
Example 5a
(Reduced


Ingredients
Number
(Torr at 25° C.)
(Traditional)
Low Volatile)














Benzyl Alcohol
100-51-6
0.158000
0.10
0.10


Methyl Phenyl Carbinyl
93-92-5
0.203000
0.32
0.40


Acetate






d-Limonene
5989-27-5
1.54000000
1.00
1.00


Benzyl Acetate
140-11-4
0.304000
5.86
7.32


Beta Gamma Hexenol
928-96-1
2.126000
0.40
0.40


Cis 3 Hexenyl Acetate
3681-71-8
1.219000
0.20
0.20


Linalyl Acetate
115-95-7
0.077400
1.00
1.00


Jasmal
18871-14-2
0.004340
3.21
4.01


Indol
120-72-9
0.029800
0.10
0.10


Hydroxycitronellal
107-75-5
0.003180
3.21
4.01


Helional
1205-17-0
0.002700
4.01
5.02


Geranyl Acetate
105-87-3
0.009760
3.21
4.01


Geraniol
106-24-1
0.013300
4.01
5.02


Florosa Q
63500-71-0
0.005570
0
9.03


Cinnamic Alcohol
104-54-1
0.005720
0.20
0.20


Cinnamic Aldehyde
104-55-2
0.02650000
0.06
0.06


Cis Jasmone
488-10-8
0.020100
0.50
0.50


Citronellol
106-22-9
0.032900
4.01
5.01


Citronellyl Acetate
150-84-5
0.013700
3.21
4.01


Citronellyl
7492-67-3
0.009670
0.10
0.10


Oxyacetaldehyde






Cyclemax
7775-00-0
0.018200
0.32
0.40


Cyclo Galbanate
68901-15-5
0.003230
0.20
0.20


Cymal
103-95-7
0.008810
1.61
2.01


Ethyl Linalool
10339-55-6
0.005200
8.04
10.03


Florhydral
125109-85-5
0.020700
0.16
0.20


Majantol
103694-68-4
0.002240
3.21
4.01


Phenyl Ethyl Acetate
103-45-7
0.056400
0.40
0.40


Phenyl Ethyl Alcohol
60-12-8
0.074100
14.45
18.06


Ambrettolide
28645-51-4
0.000001
1.00
1.00


Cis-3-Hexenyl
65405-77-8
0.000246
1.00
0.50


Salicylate






Benzyl Salicylate
118-58-1
0.00017500
16.61
2.51


Hedione ® HC
24851-98-7
0.000710
8.03
4.01


Iso-E Super ®
54464-57-2
0.000538
10.03
5.02


Phenyl Acetaldehyde
101-48-4
0.55600000
0.20
0.10


Dimethyl Acetal













Total
100
100
















TABLE 11







Fragrance Example 6 (10 Volatile Fragrance Materials)














Vapor Pressure
Parts



Ingredients
CAS Number
(Torr at 25° C.)
(wt %)
















Tetra-Hydro
78-69-3
0.115
9.85



Linalool






Terpinyl acetate
80-26-2
0.0392
12.21



Dimethyl Benzyl
151-05-3
0.0139
11.96



Carbinyl Acetate






Dimethyl Benzyl
100-86-7
0.088844
9.35



Carbinol






Phenyl Ethyl
60-12-8
0.074100
7.60



alcohol






Laevo Carvone
6485-40-1
0.0656
9.35



Indole
120-72-9
0.0298
7.29



Ethyl Safranate
35044-59-8
0.0266
12.09



Indocolore
2206-94-2
0.0255
10.09



Eugenol
97-53-0
0.0104
10.21










Total
100.00

















TABLE 12







Fragrance Example 7 (Fresh Floral GF 6-7 Accord - 40.14 wt % of Low


Volatile Fragrance Materials)












Vapor Pressure
Parts


Ingredients
CAS Number
(Torr at 25° C.)
(wt %)













Ligustral or
68039-49-6
0.578000
0.15


Triplal





Benzyl acetate
140-11-4
0.164000
0.31


Verdox
88-41-5
0.103000
5.38


Phenethyl alcohol
60-12-8
0.074100
1.54


Indole
120-72-9
0.029800
0.02


Heliotropin
120-57-0
0.010400
1.23


gamma-
706-14-9
0.008520
0.38


Decalactone





Florosa Q
63500-71-0
0.005570
15.38


Ethyl linalool
10339-55-6
0.005200
26.15


Isoeugenol
97-54-1
0.005190
0.08


alpha-Irone
79-69-6
0.004190
1.54


Vanillin
121-33-5
0.001940
6.15


Dimethyl benzyl
10094-34-5
0.001680
1.54


carbinyl butyrate





Methyl beta-
93-08-3
0.000957
0.77


naphthyl ketone





Methyl
24851-98-7
0.000710
30.60


dihydrojasmonate





Benzyl salicylate
118-58-1
0.000175
7.69


Polysantol
107898-54-4
0.000117
0.77


Lrg 201
4707-47-5
0.000029
0.31




Total
100.00
















TABLE 13







Fragrance Example 8 (Traditional Floral Accord - 54.00 wt % of Low


Volatile Fragrance Materials)












Vapor Pressure
Parts


Ingredients
CAS Number
(Torr at 25° C.)
(wt %)













Benzyl acetate
140-11-4
0.1640
5.5


Linalool
78-70-6
0.0905
5.0


Phenethyl alcohol
60-12-8
0.0741
8.0


Indole
120-72-9
0.0298
0.5


α-Terpineol
98-55-5
0.0283
1.5


Geranyl acetate
105-87-3
0.0256
2.5


Cymal
103-95-7
0.00881
3.0


Hydroxycitronellal
107-75-5
0.00318
11.5


Majantol
103694-68-4
0.00224
8.5


Hexyl cinnamic
101-86-0
0.000697
4.0


aldehyde





iso gamma super
68155-66-8
0.000565
12.50


Sandalore
65113-99-7
0.000625
18.75


Habanolide
111879-80-2
0.00000431
18.75








Total
100.00
















TABLE 14







Fragrance Examples 9, 10, 11 and 12 (Traditional Flora Magnifica -


Greater than 30 wt % of Low Volatile Fragrance Materials)












Fragrance
Fragrance
Fragrance
Fragrance



Example
Example
Example
Example



9
10
11
12


Ingredients
Weight %
Weight %
Weight %
Weight %














Flora Magnifica 1
86.96
83.33
74.07
68.97


Ethylene
4.35
4.167
3.704
6.90


Brassylate






Methyl Dihydro
4.35
8.33
14.82
13.79


Jasmonate






Iso-E Super ®
4.35
4.167
7.407
10.35


Total
100
100
100
100


Wt % Low Volatile
45
47
53
56


Fragrance Materials






1 Fragrance Example 4a.














TABLE 15







Fragrance Examples 13, 14, 15 and 16 (Traditional Muguesia


Magnifica - Greater than 30 wt % of Low Volatile Fragrance


Materials)












Fragrance
Fragrance
Fragrance
Fragrance



Example
Example
Example
Example



13
14
15
16


Ingredients
Weight %
Weight %
Weight %
Weight %














Muguesia Magnifica 1
86.96
83.33
74.07
68.97


Ethylene
4.35
4.17
3.70
6.90


Brassylate






Methyl Dihydro
4.35
8.33
14.82
13.79


Jasmonate






Iso-E Super ®
4.35
4.17
7.41
10.35


Total
100
100
100
100


Wt % Low Volatile
45
47
53
56


Fragrance Materials






1 Fragrance Example 5a.







Fragrance example 17 (as disclosed in Table 16) is composed of 68.51 wt % of volatile fragrance materials and 31.49 wt % of low volatile fragrance materials, wherein the wt % is relative to the total weight of the fragrance component.









TABLE 16







Fragrance Example 17 (Comparative Fragrance 1 - 31.49 wt % of Low


Volatile Fragance Materials)













Amount












CAS
Vapor Pressure
Parts by
Parts


Ingredients
Number
(Torr at 25° C.)
Weight
(wt %)














Limonene
5989-27-5
1.541
2576
30.04


Cis-3-Hexenol
928-96-1
1.039
21
0.24


Zestover 6
78-70-6
0.578
1
0.01


Linalol
78-70-6
0.0905
553
6.45


Aphermate 4 (10% DIPG) 7
25225-08-5
0.0678
7
0.08


Cyclosal
535-86-4
0.0311
35
0.41


Coranol
83926-73-2
0.0210
371
4.33


Sclareolate ®* 1
319002-92-1
0.0196
630
7.35


3-Methoxy-7,7-dimethyl-l 0-
216970-21-7
0.0196
371
4.33


methylene-bicyclo[4.3.1]






decane






Cedramber 2
19870-74-8
0.0128
1050
12.24


Ambrox ®*
6790-58-5
0.00934
1
0.01


Decal
706-14-9
0.00852
21
0.24


Damascone Alpha* (10% DIPG) 7
24720-09-0
0.00830
9.1
0.11


(Methoxymethoxy)Cyclododecane
42604-12-6
0.00686
182
2.12


Lilial ®
80-54-6
0.00444
26
0.30


γ-Undecalactone*
104-67-6
0.00271
21
0.24


Calone ®* 3
28940-11-6
0.000831
50
0.58


Paradisone 5®*
24851-98-7
0.000710
1000
11.66


Galaxolide ® (70% MIP Extra) 7
1222-05-5
0.000414
700
8.16


Exaltenone
14595-54-1
0.0000964
950
11.08









Total
8575.10
100 wt %





*origin: Firmenich SA (Geneva, Switzerland).



1 Propyl (S)-2-(1,1-dimethylpropxy)propanoate.




2 8-Methoxy-2,6,6,8-tetramethyl-tricyclo[5.3.1.0(1,5)]undecane.




3 7-Methyl-2H,4H-1,5-benzodioxepin-3-one.




4 1-(3,3-dimethyl-1-cyclohexyl)ethyl formate; origin: International Flavors & Fragrances.




5 Methyl dihydrojasmonate.




6 Linalool.




7 Fragrance materials added as dilutions in a non-volatile solvent. For the purposes of calculating the fragrance oil composition actual fragrance materials levels added are used.







Fragrance example 18 (as disclosed in Table 17) is composed of 90.63 wt % of volatile fragrance materials and 9.37 wt % of low volatile fragrance materials, wherein the wt % is relative to the total weight of the fragrance component.









TABLE 17







Fragrance Example 18 (Comparative Fragrance 2 - 9.37 wt % of Low Volatile


Fragance Materials)













Amount












CAS
Vapor Pressure
Parts by
Parts


Ingredients
Number
(Torr at 25° C.)
Weight
(wt %)














D-Limonene
5989-27-5
1.540
50.00
5.21


cis-3-Hexenol (10% in DPG) 4
928-96-1
1.040
0.5
0.05


Acetophenone (10% in DPG) 4
98-86-2
0.299
1.00
0.10


Methylphenyl Acetate
101-41-7
0.176
10.00
1.04


Dihydromyrcenol
18479-58-8
0.166
50.00
5.21


Benzyl acetate
140-11-4
0.164
60.00
6.25


Tetra-Hydro Linalool
n/a
0.115
50.00
5.21


n-Undecanal
n/a
0.102
5.00
0.52


Linalool
78-70-6
0.0905
40.00
4.17


Phenylethyl Alcohol
n/a
0.0559
245.00
25.53


Allyl amyl glycolate
67634-00-8
0.04000
2.00
0.21


(10% in DPG) 4






Indole (10% in DPG) 4
120-72-9
0.02980
1.00
0.10


Alpha-Terpineol
98-55-5
0.02830
30.00
3.13


Diphenyl Oxide
101-84-8
0.02230
5.00
0.52


L-Citronellol
7540-51-4
0.01830
80.00
8.34


Beta-Ionone
14901-07-6
0.01690
5.00
0.52


Alpha-Ionone
127-41-3
0.01440
15.00
1.56


Dimethyl benzyl carbinyl acetate
151-05-3
0.01390
30.00
3.13


Geraniol
106-24-1
0.01330
40.00
4.17


Nerol
n/a
0.01330
20.00
2.08


Lilial ® 1
80-54-6
0.00444
60.00
6.25


Gamma-Undecalactone
104-67-6
0.00271
15.00
1.56


Amyl salicylate
2050-08-0
0.00144
25.00
2.61


Galaxolide ®
1222-05-5
0.000414
20.00
2.08


cis-3-Hexenyl salicylate
65405-77-8
0.000246
20.00
2.08


Ethylene Brassylate
105-95-3
0.00000000313
30.00
3.13


Styrolyl Acetate 5
n/a
n/a
20.00
2.08


Decenol trans-9 3
n/a
n/a
15.00
1.56


Geranium oil 2
n/a
n/a
15.00
1.56









Total
959.5
100 wt %






1 Benzenepropanal, 4-(1,1-dimethylethyl)-α-methyl-.




2 Natural oil that is judged to be of moderate volatility for the purposes of calculating levels of the volatile fragrance materials.




3 Proprietary oil that is judged to be of moderate volatile for the purposes of calculating levels of the volatile fragrance materials.




4 Fragrance materials added as dilutions in a non-volatilee solvent. For the purposes of calculating the fragrance oil composition actual fragrance materials levels added are used.




5 Unknown oil that is judged to be of low volatility for the purposes of calculating levels of the volatile fragrance materials.







Example 2
Single Fragrance Material Compositions Containing Fragrance Oils and Substantially Non-Odorous Fragrance Fixatives

Compositions A, C, E, G, I, K, M, O, Q, S, U, W, Y, AA, and CC are examples of compositions according to the present invention, made with single fragrance materials and the substantially non-odorous fragrance fixatives, respectively. In parallel, control Compositions B, D, F, H, J, L, N, P, R, T, V, X, Z, BB, and DD are prepared without a substantially non-odorous fragrance fixative as a control. They are prepared by admixture of the components in Tables 18(a) and 18(b), in the proportions indicated.









TABLE 18(a)







Single Fragrance Material Compositions









Single Fragrance Material Composition (wt %1)























Ingredients
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P





Dimethyl Benzyl
1  
1






1  
1








Carbinol


Eugenol


1  
1






1  
1






Phenylethyl




1  
1






1  
1




Alchol


Fragrance A2






1
1






1
1


Piperonyl butoxide
2.2
0
2.0
0
2.2
0
0.5-5
0










Poly(PG)monobutyl








2.2
0
2.0
0
1.8
0
0.5-5
0


ether








Ethanol
to 100






1Wt % is relative to the total weight of the composition.




2Can be any one of the single fragrance materials of Table 2 or 3.














TABLE 18(b)







Single Fragrance Material Compositions









Single Fragrance Material Composition (wt %1)





















Ingredients
Q
R
S
T
U
V
W
X
Y
Z
AA
BB
CC
DD





Indole
1  
1






1
1






Eugenol


1  
1






1
1




Dimethyl




1  
1






1
1


Benzyl


Carbinol


Phenylethyl






1  
1








Alchol


Triglycol
1.3

0.9

1.0

1.2















Ethanol
To 100






1Wt % is relative to the total weight of the composition.







Composition EE is an example of a composition according to the present invention, made with single fragrance material and the substantially non-odorous fragrance fixative, respectively, that are particularly suited to olfactive evaluation. In parallel, control Composition FF is prepared without a substantially non-odorous fragrance fixative as a control. All the compositions are prepared by admixture of the components in Table 18(c), in the proportions indicated.









TABLE 18(c)







Single Fragrance Material Compositions









Single Fragrance Material Composition (wt %) 1









Ingredients
EE
FF





Fragrance A 2
1-7  
1-7


Modulator 3
1-15.0
0.0








Ethanol
to 100






1 Wt % is relative to the total weight of the composition.




2 Can be any one of the fragrance materials disclosed in Tables 2 and 3.




3 Can be any one of the substantially non-odorous fragrance fixatives not already disclosed in Tables 18(a) and 18(b).







Tables 18(d) provides test compositions comprising the a single volatile fragrance material (as disclosed in Table 3) with a substantially non-odorous fragrance fixative (as disclosed in Table 1) that are particularly suited to analytical measurements. All of the compositions are prepared by admixture of the components described in Table 18(d) in the proportions indicated.









TABLE 18(d)







Single Volatile Fragrance Material Compositions










Test Composition
Reference Composition


Ingredients
(wt % 1)
(wt % 1)





Volatile Fragrance Material 2
1.0-3.0
1.0-3.0


Triethyl citrate
0.25 to 2.0
0.25 to 2.0


Ethanol
 75.0
 75.0


Fixative 3
 0.1-10.0
  0.0


Water
qsp
qsp


Total
100.0
100.0






1 Wt % is relative to the total weight of the composition.




2 Can be any one of the volatile fragrance material as disclosed in Table 3.




3 Can be any one of the substantially non-odorous fragrance fixative as disclosed in Table 1.







Example 3
Compositions Comprising Substantially Non-Odorous Fragrance Fixatives

Composition A1 is an example of a fragrance composition according to the present invention, made with any of the fragrance examples 1-3, 4b, 5b and 18, respectively. Composition B1 is an example of a fragrance composition containing traditional or higher levels of low volatile fragrance materials, made with any of the fragrance examples 4a, 5a, and 7-17, respectively. In parallel, a control composition C1 is prepared by replacing the different substantially non-odorous fragrance fixative by the same amount of deionized water. All of the compositions are prepared by admixture of the components described in Table 19(a) in the proportions indicated.









TABLE 19(a)







Fragrance Composition











Fragrance Composition




(wt %) 1












Ingredients
A1
B1
C1







Fragrance A1 2
  2-15





Fragrance B 3

  2-15




Fragrance A1 or B


2-15










Ethanol
60-99.99



Butylated Hydroxy
0-0.07



Toluene













Modulator A 4
0.1-20
0.1-20











Deionized water
to 100.00








1 Wt % is relative to the total weight of the composition.





2 Can be any one of fragrance examples 1-3, 4b, 5b, and 18.





3 Can be any one of fragrance examples 4a, 5a, and 7-17.





4 Can be any one of the substantially non-odorous fragrance fixative as disclosed in Table 1.







Tables 19(b) provides test compositions (MOD1 to MOD43) comprising the volatile fragrance formulation of fragrance example 6 (as disclosed in Table 11) with a substantially non-odorous fragrance fixative (as disclosed in Table 1) that are particularly suited to analytical measurements. All of the compositions are prepared by admixture of the components described in Table 19(b) in the proportions indicated.









TABLE 19(b)







Compositions comprising fragrance with 10 Volatile


Fragrance Materials










Test composition
Reference composition



(wt %)
(wt %)


Ingredients
MOD 1 to 43
REF





Fragrance A 2
  7.0
  7.0


Triethyl citrate
0.25 to 1.0
0.25 to 1.0


Ethanol
 75.0
 75.0


Fixative 3
 15.0
  0.0


Water
qsp
qsp


Total
100.0
100.0






1 Wt % is relative to the total weight of the composition.




2 Fragrance Example 6 (as disclosed in Table 11).




3 Can be any one of the substantially non-odorous fragrance fixative no. 1- 3, 6-10, 12-13, 15-19, 21, 26-28, 32, 47, 49-50, 52, 63, 84, 101, 106, 121, 128, 130, 138, 142, 143, 144, 151, 152, 159, 173, 180, and 189 as disclosed in Table 1.







Tables 19(c) provides test compositions comprising the volatile fragrance formulation of fragrance example 6 (as disclosed in Table 11) with a substantially non-odorous fragrance fixative (as disclosed in Table 1) that are particularly suited to analytical measurements. All of the compositions are prepared by admixture of the components described in Table 19(c) in the proportions indicated.









TABLE 19(c)







Compositions comprising fragrance with 10 Volatile


Fragrance Materials










Test composition
Reference composition


Ingredients
(wt % 1)
(wt % 1)





Fragrance A 2
0.4-7.0
0.4-7.0


Triethyl citrate
0.25 to 2.0
0.25 to 2.0


Ethanol
 75.0
 75.0


Fixative 3
  1-15.0
  0.0


Water
qsp
qsp


Total
100.0
100.0






1 Wt % is relative to the total weight of the composition.




2 Fragrance Example 6 (as disclosed in Table 11).




3 Can be any one of the substantially non-odorous fragrance fixative no. 4-5, 11, 14, 20, 22-25, 29-31, 33-46, 48, 51, 53-62, 64-83, 85-100, 102-105, 107-120, 122-127, 129, 131-137, 139-141, 145-150, 153-158, 160-172, 174-179, 181-188, and 190 as disclosed in Table 1.







Example 4
Exemplary Product Compositions

Compositions I, II, III and IV are examples of body spray compositions according to the present invention. They are prepared by admixture of the components described in Table 20, in the proportions indicated.









TABLE 20







Body Spray Compositions










CAS
Compositions (wt % 1)












Ingredients
Number
I
II
III
IV















Denatured Ethanol
64-17-5
39.70
59.45
39.70
39.70


Water
7732-18-5

0.75




Dipropylene Glycol
25265-71-8
15.00

15.00
15.00


Isopropyl Myristate
110-27-0
1.00

1.00
1.00


Zinc
127-82-2
0.50

0.50
0.50


Phenosulphonate







Cavasol ® W7
128446-36-6

1.00




methylated







Beta-cyclodextrin







Fragrance 2

1.20
1.20
1.20
1.20


Fragrance Fixative 3

2.60
2.60
2.60
2.60


Propane
74-98-6
4.86

4.86
4.86


Isobutane
72-28-5
27.14

27.14
27.14


1,1-Difluoroethane
75-37-6
8.00
35.00
8.00
8.00


(HFC-152a)
















Total
100.00
100.00
100.00
100.00






1 wt % relative to the total weight of the composition.




2 Can be any one of Fragrances Examples 1, 2, 3, 4a, 4b, 5a, 5b, and 7-17.




3 Can be any one of the substantially non-odorous fragrance fixatives disclosed in Table 1.







Composition V, VI and VII are examples of body lotion compositions according to the present invention. They are prepared by admixture of the components as described in Table 21, in the proportions indicated.









TABLE 21







Body Lotion Composition










CAS
Compositions (wt % 1)











Ingredients
Number
V
VI
VII





Water
7732-18-5
qsp
qsp
qsp




100%
100%
100%


Trilon ® B
64-02-8
0.05
0.05
0.05


Carbopol ® ETD 2050
9003-01-4
0.2
0.2
0.2


Pemulen ™ TR1
9063-87-0
0.2
0.2
0.2


Nexbase ® 2008
68037-01-4
8
8
8


Silicone V100
63148-62-9
6
6
6


Fragrance Fixative 3

3
3
3


Tris Amino ™ Ultra
102-71-6
0.4
0.4
0.4


Pur






Fragrance 2

3
3
3


Preservatives

qs
qs
qs










Total
100.00
100.00
100.00






1 wt % relative to the total weight of the composition.




2 Can be any one of the Fragrances Examples 1, 2, 3, 4a, 4b, 5a, 5b, and 7-17.




3 Can be any one of the substantially non-odorous fragrance fixatives disclosed in Table 1.







Example 5
Olfactive Test Results

Compositions disclosed in Tables 18(a)-18(c), and 19(a) are applied to glass slides in accordance with the protocol described in the Method Section and a panel of 6-11 experienced panelists evaluated the perceived fragrance profile at initial time 0, then at various time points, typically 1 hour, 2 hours, 3 hours, 4 hours and 6 hours post application. Panelists are asked to score the compositions for the longevity on a scale of 0 to 5, wherein 0 represents a no fragrance is detected and 5 represents a very strong fragrance intensity is detected; and for fragrance profile fidelity on a scale of 0 to 3 wherein 0 represents not detectable and 3 represents it being the dominant character. The results of the panelists are then averaged and discussed below.


(a) Effects of the Substantially Non-Odorous Fragrance Fixatives on Single Fragrance Material Compositions



FIG. 1 shows the fragrance intensity profile of Composition A as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance fixative Piperonyl butoxide, on the single fragrance material, Dimethyl Benzyl Carbinol. Addition of the fixative maintains the intensity of the fragrance material whilst the control, Composition B, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p=0.0061) at 95% significance level (i.e., p<0.05).



FIG. 2 shows the fragrance intensity profile of Composition C as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance fixative Piperonyl butoxide, on the single fragrance material, Eugenol. Addition of the fixative (Piperonyl butoxide) maintains the intensity of the fragrance material whilst the control, Composition D, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p<0.0001) and at 3 hours (p=0.0231) at 95% significance level (i.e., p<0.05).



FIG. 3 shows the fragrance intensity profile of Composition I as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance fixative Poly(PG)monobutyl ether, on the single fragrance material, Dimethyl Benzyl Carbinol. Addition of the fixative (Poly(PG)monobutyl ether) maintains the intensity of the fragrance material whilst the control, Composition J, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 0 hours (p=0.0060) and 1 hour (p=0.0443) at 95% significance level (i.e., p<0.05) and at 3 hours (p=0.0873) at 90% significance (i.e., p<0.1).



FIG. 4 shows the fragrance intensity profile of Composition K as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance fixative Poly(PG)monobutyl ether, on the single fragrance material, Eugenol. Addition of the fixative (Poly(PG)monobutyl ether) maintains the intensity of the fragrance material whilst the control, Composition L, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p<0.0001), at 3 hours (p<0.0001) and at 6 hours (p=0.0067) at 95% significance level (i.e., p<0.05).



FIG. 5 shows the fragrance intensity profile of Composition M as evaluated by 10 panelists, which comprises the substantially non-odorous fragrance fixative Poly(PG)monobutyl ether, on the single fragrance material, phenethyl alcohol (PEA). Addition of the fixative (Poly(PG)monobutyl ether) maintains the intensity of the fragrance material whilst the control, Composition N, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 0 hours (p=0.0530) at 90% significance level (i.e., p<0.1) and at 1 hour (p<0.0034) and at 3 hours (p<0.0034) at 95% significance level (i.e., p<0.05).



FIG. 6 shows the fragrance intensity profile of Composition Q as evaluated by 11 panelists, which comprises the substantially non-odorous fragrance fixative Triglycol, on the single fragrance material Indole. Addition of the fixative (Triglycol) maintains the intensity of the fragrance material whilst the control, Composition R, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p<0.0014) at 95% significance level (i.e., p<0.05).



FIG. 7 shows the fragrance intensity profile of Composition S as evaluated by 11 panelists, which comprises the substantially non-odorous fragrance fixative Triglycol, on the single fragrance material Eugenol. Addition of the fixative (Triglycol) maintains the intensity of the fragrance material whilst the control, Composition T, in the absence of the substantially non-odorous fragrance fixative, drops in fragrance intensity profile over the 6 hours. The substantially non-odorous fragrance fixative acts to maintain the continued evaporation over time of the fragrance material. Statistical analysis using the Tukey correction for multiple comparisons confirms the statistically significant difference at 1 hour (p<0.0144) at 95% significance level (i.e., p<0.05).


(b) Effects of Substantially Non-Odorous Fragrance Fixatives on the Fragrance Profile Longevity of Compositions Having Reduced Levels of Low Volatile Fragrance Materials (Between 10 to 30 wt % Relative to the Total Weight of the Fragrance Component) Vs. Compositions Having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt % Relative to the Total Weight of the Fragrance Component) and No Substantially Non-Odorous Fragrance Fixative


Panelists are asked to score the compositions for the intensity of the fragrance on a scale of 0 to 5, wherein 0 represents no fragrance intensity is detected and 5 represents a very strong fragrance intensity is detected. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance fixative and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A1 on fragrance profile longevity versus control Compositions C1 in the absence of the substantially non-odorous fragrance fixatives. Alternatively, the results show the effect of the substantially non-odorous fragrance fixative and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A1 on fragrance profile longevity versus traditional Compositions B1 in the presence of the substantially non-odorous fragrance fixative.


Fragrance profile longevity, particularly intensity of the characters attributable to the volatile fragrance materials, are maintained for up to at least 6 hours in the presence of the substantially non-odorous fragrance fixative whilst it drops in the absence of the substantially non-odorous fragrance fixative.


(c) Effects of the Substantially Non-Odorous Fragrance Fixatives on the Fragrance Profile Fidelity of Compositions Having Reduced Levels of Low Volatile Fragrance Materials (Between 10 to 30 wt % Relative to the Total Weight of the Fragrance Component) Vs. Compositions Having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt % Relative to the Total Weight of the Fragrance Component) and No Substantially Non-Odorous Fragrance Fixative


Panelists are also asked to score the composition for the fragrance profile fidelity. In particular, the panelists are asked to score the dominance of the floral character attributable to the volatile fragrance materials on a scale of 0 to 3 wherein 0 represents not detectable and 3 represents it being the dominant character. The results of the panel test are then averaged. The results show the effect of the substantially non-odorous fragrance fixative for the inventive Compositions A1 on fragrance profile fidelity versus control Compositions C1 in the absence of the substantially non-odorous fragrance fixative.


Fragrance profile fidelity are maintained by the substantially non-odorous fragrance fixative over time for up to 6 hours in the presence of the substantially non-odorous fragrance fixative whilst it drops in the absence of the substantially non-odorous fragrance fixative (data not shown).


Example 6
Analytical Evaporation Test Results

Using the analytical evaporation Test Method 3, it is possible to measure the amount of a volatile fragrance material or each component of a perfume mixture that remains as the fragrance mixture evaporates. Test compositions may comprise any one of the volatile fragrance material as disclosed in Table 3 and a substantially non-odorous fragrance fixative, as disclosed in Table 1. Alternatively, test compositions may comprise a mixture of 10 volatile perfume materials, as disclosed in Table 11 (Fragrance Example 6), and a substantially non-odorous fragrance fixative, as disclosed in Table 1. Examples of suitable test compositions include the compositions disclosed in Table 18(d), and Compositions MOD1 to MOD43 in Table 19(b) and Compositions in Table 19(c). The test compositions are introduced in the aluminum containers at the set temperature for pre-determined periods of time in accordance with the protocol described in Test Method 3.


For Compositions MOD1 to MOD43, indole is one of the components of the 10 PRMs mixture of Table 11. Control compositions containing the full 10 PRMs, or one component (e.g., indole), without the substantially non-odorous fragrance fixative are run alongside the test compositions. The average profile for the control composition is plotted against the individual profile for the indole component from the test composition containing the 10 PRMs mixture of Table 11 with the substantially non-odorous fragrance fixatives. The error associated with the method is determined by running replicate evaporation experiments on the control composition. An average evaporation profile of the control composition as well as the 95% confidence interval at each time point are calculated from the replicates.


It is useful to consider the difference (Δ) in the % of remaining fragrance material between each of the test composition (MOD) and their respective control composition (REF) at each experimental time points (e.g., 30 mins, 60 mins and 180 mins) to determine the effect of the substantially non-odorous fragrance fixative on the volatile PRMs in a mixture. The difference (Δ) in the % of remaining of a given fragrance material is calculated as follows:





Δ=% remaining of given fragrance material in test composition (MOD)−% remaining of same fragrance material in control composition (REF)


The difference (Δ) can then be plotted (data not shown) for each of the perfume materials in the mixture at each of the time points. For ease of reference, the applicant has summarize the effect of the substantially non-odorous fragrance fixative on only one volatile fragrance component (e.g., indole) of the mixture, to serve as a representative of all of the volatile fragrance materials.


(a) Effects of Tergitol® 15-S-7 on Composition Having Volatile Fragrance Materials



FIG. 8 shows the effect of the substantially non-odorous fragrance fixative Tergitol® 15-S-7 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD1). With reference to FIG. 8, indole has a difference (Δ) of 14% after 30 mins, 24% after 60 mins, and 80% after 3 hours. Addition of the Tergitol® 15-S-7 in the test composition (MOD1) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Tergitol® 15-S-7, drops in fragrance concentration over the 3 hours. Thus, Tergitol® 15-S-7 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(b) Effects of PPG-7-Buteth-10 on Composition Having Volatile Fragrance Materials



FIG. 9 shows the effect of the substantially non-odorous fragrance fixative PPG-7-Buteth-10 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD2). With reference to FIG. 9, indole has a difference (Δ) of 21% after 30 mins, 33% after 60 mins, and 80% after 3 hours. Addition of the Tergitol® in the test composition (MOD2) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of PPG-7-Buteth-10, drops in fragrance concentration over the 3 hours. Thus, PPG-7-Buteth-10 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(c) Effects of Nikkol PBC-33 on Composition Having Volatile Fragrance Materials



FIG. 10 shows the effect of the substantially non-odorous fragrance fixative Nikkol PBC-33 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD3). With reference to FIG. 10, indole has a difference (Δ) of 12% after 30 mins, 24% after 60 mins, and 76% after 3 hours. Addition of the Nikkol PBC-33 in the test composition (MOD3) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Nikkol PBC-33, drops in fragrance concentration over the 3 hours. Thus, Nikkol PBC-33 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(d) Effects of Neodol 45-7 Alcohol Ethoxylate on Composition Having Volatile Fragrance Materials



FIG. 11 shows the effect of the substantially non-odorous fragrance fixative Neodol 45-7 Alcohol Ethoxylate on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD4). With reference to FIG. 11, indole has a difference (Δ) of 15% after 30 mins, 28% after 60 mins, and 76% after 3 hours. Addition of the Neodol 45-7 Alcohol Ethoxylate in the test composition (MOD4) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Neodol 45-7 Alcohol Ethoxylate, drops in fragrance concentration over the 3 hours. Thus, Neodol 45-7 Alcohol Ethoxylate acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(e) Effects of Bio-Soft N25-7 on Composition Having Volatile Fragrance Materials



FIG. 12 shows the effect of the substantially non-odorous fragrance fixative Bio-soft N25-7 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD5). With reference to FIG. 12, indole has a difference (Δ) of 16% after 30 mins, 24% after 60 mins, and 76% after 3 hours. Addition of the Bio-soft N25-7 in the test composition (MOD5) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Bio-soft N25-7, drops in fragrance concentration over the 3 hours. Thus, Bio-soft N25-7 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(f) Effects of Bio-Soft N23-6.5 on Composition Having Volatile Fragrance Materials



FIG. 13 shows the effect of the substantially non-odorous fragrance fixative Bio-soft N23-6.5 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD6). With reference to FIG. 13, indole has a difference (Δ) of 15% after 30 mins, 28% after 60 mins, and 77% after 3 hours. Addition of the Bio-soft N23-6.5 in the test composition (MOD6) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Bio-soft N23-6.5, drops in fragrance concentration over the 3 hours. Thus, Bio-soft N23-6.5 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(g) Effects of Cremophor® A 25 on Composition Having Volatile Fragrance Materials



FIG. 14 shows the effect of the substantially non-odorous fragrance fixative Cremophor® A 25 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD7). With reference to FIG. 14, indole has a difference (Δ) of 18% after 30 mins, 32% after 60 mins, and 68% after 3 hours. Addition of the Cremophor® A 25 in the test composition (MOD7) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Cremophor® A 25, drops in fragrance concentration over the 3 hours. Thus, Cremophor® A 25 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(h) Effects of Bio-Soft N91-8 on Composition Having Volatile Fragrance Materials



FIG. 15 shows the effect of the substantially non-odorous fragrance fixative Bio-soft N91-8 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD8). With reference to FIG. 15, indole has a difference (Δ) of 11% after 30 mins, 25% after 60 mins, and 71% after 3 hours. Addition of the Bio-soft N91-8 in the test composition (MOD8) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Bio-soft N91-8, drops in fragrance concentration over the 3 hours. Thus, Bio-soft N91-8 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(i) Effects of Genapol® C-100 on Composition Having Volatile Fragrance Materials



FIG. 16 shows the effect of the substantially non-odorous fragrance fixative Genapol® C-100 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD9). With reference to FIG. 16, indole has a difference (Δ) of 13% after 30 mins, 28% after 60 mins, and 72% after 3 hours. Addition of the Genapol® C-100 in the test composition (MOD9) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Genapol® C-100, drops in fragrance concentration over the 3 hours. Thus, Genapol® C-100 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(j) Effects of Rhodasurf® LA 30 on Composition Having Volatile Fragrance Materials



FIG. 17 shows the effect of the substantially non-odorous fragrance fixative Rhodasurf® LA 30 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD10). With reference to FIG. 17, indole has a difference (Δ) of 15% after 30 mins, 28% after 60 mins, and 75% after 3 hours. Addition of the Rhodasurf® LA 30 in the test composition (MOD10) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Rhodasurf® LA 30, drops in fragrance concentration over the 3 hours. Thus, Rhodasurf® LA 30 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(k) Effects of Poly(Ethylene Glycol) Methyl Ether on Composition Having Volatile Fragrance Materials



FIG. 18 shows the effect of the substantially non-odorous fragrance fixative Poly(ethylene glycol) methyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD11). With reference to FIG. 18, indole has a difference (Δ) of 15% after 30 mins, 31% after 60 mins, and 84% after 3 hours. Addition of the Poly(ethylene glycol) methyl ether in the test composition (MOD11) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Poly(ethylene glycol) methyl ether, drops in fragrance concentration over the 3 hours. Thus, Poly(ethylene glycol) methyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(l) Effects of Arlamol™ PS11E on Composition Having Volatile Fragrance Materials



FIG. 19 shows the effect of the substantially non-odorous fragrance fixative Arlamol™ PS11E on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD12). With reference to FIG. 19, indole has a difference (Δ) of 9% after 30 mins, 23% after 60 mins, and 59% after 3 hours. Addition of the Arlamol™ PS11E in the test composition (MOD12) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Arlamol™ PS11E, drops in fragrance concentration over the 3 hours. Thus, Arlamol™ PS11E acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(m) Effects of Brij® S100 on Composition Having Volatile Fragrance Materials



FIG. 20 shows the effect of the substantially non-odorous fragrance fixative Brij® S100 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD13). With reference to FIG. 20, indole has a difference (Δ) of 7% after 30 mins, 18% after 60 mins, and 61% after 3 hours. Addition of the Brij® S100 in the test composition (MOD13) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Brij® S100, drops in fragrance concentration over the 3 hours. Thus, Brij® S100 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).

    • (n) Effects of Brij® C-10 on Composition Having Volatile Fragrance Materials



FIG. 21 shows the effect of the substantially non-odorous fragrance fixative Brij® C-58 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD14). With reference to FIG. 21, indole has a difference (Δ) of 9% after 30 mins, 25% after 60 mins, and 73% after 3 hours. Addition of the Brij® C-58 in the test composition (MOD14) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Brij® C-58, drops in fragrance concentration over the 3 hours. Thus, Brij® C-58 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).

    • (o) Effects of Pluronic® F-127 on Composition Having Volatile Fragrance Materials



FIG. 22 shows the effect of the substantially non-odorous fragrance fixative Pluronic® F-127 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD15). With reference to FIG. 22, indole has a difference (Δ) of 7% after 30 mins, 20% after 60 mins, and 62% after 3 hours. Addition of the Pluronic® F-127 in the test composition (MOD15) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Pluronic® F-127, drops in fragrance concentration over the 3 hours. Thus, Pluronic® F-127 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(p) Effects of Bio-Soft N1-5 on Composition Having Volatile Fragrance Materials



FIG. 23 shows the effect of the substantially non-odorous fragrance fixative Bio-soft N1-5 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD16). With reference to FIG. 23, indole has a difference (Δ) of 16% after 30 mins, 28% after 60 mins, and 80% after 3 hours. Addition of the Bio-soft N1-5 in the test composition (MOD16) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Bio-soft N1-5, drops in fragrance profile concentration over the 3 hours. Thus, Bio-soft N1-5 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(q) Effects of Polyoxyethylene (10) Lauryl Ether on Composition Having Volatile Fragrance Materials



FIG. 24 shows the effect of the substantially non-odorous fragrance fixative Polyoxyethylene (10) lauryl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD17). With reference to FIG. 24, indole has a difference (A) of 16% after 30 mins, 31% after 60 mins, and 80% after 3 hours. Addition of the Polyoxyethylene (10) lauryl ether in the test composition (MOD17) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Polyoxyethylene (10) lauryl ether, drops in fragrance concentration over the 3 hours. Thus, Polyoxyethylene (10) lauryl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(r) Effects of Arlamol™ PC10 on Composition Having Volatile Fragrance Materials



FIG. 25 shows the effect of the substantially non-odorous fragrance fixative Arlamol™ PC10 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD18). With reference to FIG. 25, indole has a difference (Δ) of 15% after 30 mins, 26% after 60 mins, and 68% after 3 hours. Addition of the Arlamol™ PC10 in the test composition (MOD18) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Arlamol™ PC10, drops in fragrance concentration over the 3 hours. Thus, Arlamol™ PC10 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(s) Effects of Poly(Ethylene Glycol) (18) Tridecyl Ether on Composition Having Volatile Fragrance Materials



FIG. 26 shows the effect of the substantially non-odorous fragrance fixative Poly(ethylene glycol) (18) tridecyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD19). With reference to FIG. 26, indole has a difference (Δ) of 13% after 30 mins, 25% after 60 mins, and 76% after 3 hours. Addition of the Poly(ethylene glycol) (18) tridecyl ether in the test composition (MOD19) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Poly(ethylene glycol) (18) tridecyl ether, drops in fragrance concentration over the 3 hours. Thus, Poly(ethylene glycol) (18) tridecyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(t) Effects of ALFONIC® 10-8 Ethoxylate on Composition Having Volatile Fragrance Materials



FIG. 27 shows the effect of the substantially non-odorous fragrance fixative ALFONIC® 10-8 Ethoxylate on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD20). With reference to FIG. 27, indole has a difference (Δ) of 14% after 30 mins, 30% after 60 mins, and 79% after 3 hours. Addition of the Poly(ethylene glycol) (18) tridecyl ether in the test composition (MOD20) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of ALFONIC® 10-8 Ethoxylate, drops in fragrance concentration over the 3 hours. Thus, ALFONIC® 10-8 Ethoxylate acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(u) Effects of Brij® O20-SS on Composition Having Volatile Fragrance Materials



FIG. 28 shows the effect of the substantially non-odorous fragrance fixative Brij® O20-SS on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD21). With reference to FIG. 28, indole has a difference (Δ) of 15% after 30 mins, 32% after 60 mins, and 83% after 3 hours. Addition of the Brij® O20-SS in the test composition (MOD21) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Brij® O20-SS, drops in fragrance concentration over the 3 hours. Thus, Brij® O20-SS acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(v) Effects of Diethylene Glycol Butyl Ether on Composition Having Volatile Fragrance Materials



FIG. 29 shows the effect of the substantially non-odorous fragrance fixative Diethylene glycol butyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD22). With reference to FIG. 29, indole has a difference (Δ) of 13% after 30 mins, 28% after 60 mins, and 72% after 3 hours. Addition of the Diethylene glycol butyl ether in the test composition (MOD22) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Diethylene glycol butyl ether, drops in fragrance concentration over the 3 hours. Thus, Diethylene glycol butyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(w) Effects of Ethylene Glycol Monohexadecyl Ether on Composition Having Volatile Fragrance Materials



FIG. 30 shows the effect of the substantially non-odorous fragrance fixative Ethylene glycol monohexadecyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD23). With reference to FIG. 30, indole has a difference (A) of 10% after 30 mins, 21% after 60 mins, and 77% after 3 hours. Addition of the Ethylene glycol monohexadecyl ether in the test composition (MOD23) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Ethylene glycol monohexadecyl ether, drops in fragrance concentration over the 3 hours. Thus, Ethylene glycol monohexadecyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(x) Effects of Poly(Propylene Glycol) Monobutyl Ether on Composition Having Volatile Fragrance Materials



FIG. 31 shows the effect of the substantially non-odorous fragrance fixative Poly(propylene glycol) monobutyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD24). With reference to FIG. 31, indole has a difference (Δ) of 11% after 30 mins, 24% after 60 mins, and 72% after 3 hours. Addition of the Poly(propylene glycol) monobutyl ether in the test composition (MOD24) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Poly(propylene glycol) monobutyl ether, drops in fragrance concentration over the 3 hours. Thus, Poly(propylene glycol) monobutyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(y) Effects of Dowanol™ TPnB on Composition Having Volatile Fragrance Materials



FIG. 32 shows the effect of the substantially non-odorous fragrance fixative Dowanol™ TPnB on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD25). With reference to FIG. 32, indole has a difference (Δ) of 20% after 30 mins, 24% after 60 mins, and 69% after 3 hours. Addition of the Dowanol™ TPnB in the test composition (MOD25) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Dowanol™ TPnB, drops in fragrance concentration over the 3 hours. Thus, Dowanol™ TPnB acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(z) Effects of Tripropylene Glycol on Composition Having Volatile Fragrance Materials



FIG. 33 shows the effect of the substantially non-odorous fragrance fixative Tripropylene Glycol on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD26). With reference to FIG. 33, indole has a difference (Δ) of 11% after 30 mins, 23% after 60 mins, and 69% after 3 hours. Addition of the Tripropylene Glycol in the test composition (MOD26) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Tripropylene Glycol, drops in fragrance concentration over the 3 hours. Thus, Tripropylene Glycol acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(aa) Effects of Cithrol™ on Composition Having Volatile Fragrance Materials



FIG. 34 shows the effect of the substantially non-odorous fragrance fixative Cithrol™ on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD27). With reference to FIG. 34, indole has a difference (Δ) of 12% after 30 mins, 22% after 60 mins, and 68% after 3 hours. Addition of the Cithrol™ in the test composition (MOD27) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Cithrol™, drops in fragrance concentration over the 3 hours. Thus, Cithrol™ acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(bb) Effects of Igepal® CO-630 on Composition Having Volatile Fragrance Materials



FIG. 35 shows the effect of the substantially non-odorous fragrance fixative Igepal® CO-630 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD28). With reference to FIG. 35, indole has a difference (Δ) of 21% after 30 mins, 34% after 60 mins, and 85% after 3 hours. Addition of the Igepal® CO-630 in the test composition (MOD28) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Igepal® CO-630, drops in fragrance concentration over the 3 hours. Thus, Igepal® CO-630 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(cc) Effects of Nikkol Decaglyn 3-OV on Composition Having Volatile Fragrance Materials



FIG. 36 shows the effect of the substantially non-odorous fragrance fixative Nikkol Decaglyn 3-OV on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD29). With reference to FIG. 36, indole has a difference (Δ) of 12% after 30 mins, 23% after 60 mins, and 62% after 3 hours. Addition of the Nikkol Decaglyn 3-OV in the test composition (MOD29) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Nikkol Decaglyn 3-OV, drops in fragrance concentration over the 3 hours. Thus, Nikkol Decaglyn 3-OV acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(dd) Effects of NIKKOL Hexaglyn 1-L on Composition Having Volatile Fragrance Materials



FIG. 37 shows the effect of the substantially non-odorous fragrance fixative NIKKOL Hexaglyn 1-L on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD30). With reference to FIG. 37, indole has a difference (Δ) of 10% after 30 mins, 20% after 60 mins, and 62% after 3 hours. Addition of the NIKKOL Hexaglyn 1-L in the test composition (MOD30) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of NIKKOL Hexaglyn 1-L, drops in fragrance concentration over the 3 hours. Thus, NIKKOL Hexaglyn 1-L acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(ee) Effects of Emalex CS-10 on Composition Having Volatile Fragrance Materials



FIG. 38 shows the effect of the substantially non-odorous fragrance fixative Emalex CS-10 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD31). With reference to FIG. 38, indole has a difference (Δ) of 14% after 30 mins, 24% after 60 mins, and 72% after 3 hours. Addition of the Emalex CS-10 in the test composition (MOD31) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Emalex CS-10, drops in fragrance concentration over the 3 hours. Thus, Emalex CS-10 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(ff) Effects of Dioctyl Ether on Composition Having Volatile Fragrance Materials



FIG. 39 shows the effect of the substantially non-odorous fragrance fixative Dioctyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD32). With reference to FIG. 39, indole has a difference (Δ) of 7% after 30 mins, 14% after 60 mins, and 40% after 3 hours. Addition of the Dioctyl ether in the test composition (MOD32) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Dioctyl ether, drops in fragrance concentration over the 3 hours. Thus, Dioctyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(gg) Effects of Jeecol CA-10 on Composition Having Volatile Fragrance Materials



FIG. 40 shows the effect of the substantially non-odorous fragrance fixative Jeecol CA-10 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD33). With reference to FIG. 40, indole has a difference (Δ) of 13% after 30 mins, 29% after 60 mins, and 77% after 3 hours. Addition of the Jeecol CA-10 in the test composition (MOD33) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Jeecol CA-10, drops in fragrance concentration over the 3 hours. Thus, Jeecol CA-10 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(hh) Effects of Steareth-10 on Composition Having Volatile Fragrance Materials



FIG. 41 shows the effect of the substantially non-odorous fragrance fixative Steareth-10 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD34). With reference to FIG. 41, indole has a difference (Δ) of 12% after 30 mins, 26% after 60 mins, and 72% after 3 hours. Addition of the Steareth-10 in the test composition (MOD34) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Steareth-10, drops in fragrance concentration over the 3 hours. Thus, Steareth-10 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(ii) Effects of Nonaethylene Glycol Monododecyl Ether on Composition Having Volatile Fragrance Materials



FIG. 42 shows the effect of the substantially non-odorous fragrance fixative Nonaethylene glycol monododecyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD35). With reference to FIG. 42, indole has a difference (Δ) of 17% after 30 mins, 31% after 60 mins, and 78% after 3 hours. Addition of the Nonaethylene glycol monododecyl ether in the test composition (MOD35) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Nonaethylene glycol monododecyl ether, drops in fragrance concentration over the 3 hours. Thus, Nonaethylene glycol monododecyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(jj) Effects of Glycerol Propoxylate on Composition Having Volatile Fragrance Materials



FIG. 43 shows the effect of the substantially non-odorous fragrance fixative Glycerol propoxylate on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD36). With reference to FIG. 43, indole has a difference (Δ) of 14% after 30 mins, 28% after 60 mins, and 71% after 3 hours. Addition of the Glycerol propoxylate in the test composition (MOD36) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Glycerol propoxylate, drops in fragrance concentration over the 3 hours. Thus, Glycerol propoxylate acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(kk) Effects of Glycerol Ethoxylate on Composition Having Volatile Fragrance Materials



FIG. 44 shows the effect of the substantially non-odorous fragrance fixative Glycerol ethoxylate on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD37). With reference to FIG. 44, indole has a difference (Δ) of 12% after 30 mins, 29% after 60 mins, and 80% after 3 hours. Addition of the Glycerol ethoxylate in the test composition (MOD37) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Glycerol ethoxylate, drops in fragrance concentration over the 3 hours. Thus, Glycerol ethoxylate acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(ll) Effects of Hexaethylene Glycol Monohexadecyl Ether on Composition Having Volatile Fragrance Materials



FIG. 45 shows the effect of the substantially non-odorous fragrance fixative Hexaethylene glycol monohexadecyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD38). With reference to FIG. 45, indole has a difference (Δ) of 19% after 30 mins, 29% after 60 mins, and 77% after 3 hours. Addition of the Hexaethylene glycol monohexadecyl ether in the test composition (MOD38) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Hexaethylene glycol monohexadecyl ether, drops in fragrance concentration over the 3 hours. Thus, Hexaethylene glycol monohexadecyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(mm) Effects of Aquaflex™ XL-30 on Composition Having Volatile Fragrance Materials



FIG. 46 shows the effect of the substantially non-odorous fragrance fixative Aquaflex™ XL-30 on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD39). With reference to FIG. 46, indole has a difference (Δ) of 4% after 30 mins, 20% after 60 mins, and 60% after 3 hours. Addition of the Aquaflex™ XL-30 in the test composition (MOD39) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Aquaflex™ XL-30, drops in fragrance concentration over the 3 hours. Thus, Aquaflex™ XL-30 acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(nn) Effects of Piperonyl Butoxide on Composition Having Volatile Fragrance Materials



FIG. 47 shows the effect of the substantially non-odorous fragrance fixative Piperonyl Butoxide on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD40). With reference to FIG. 47, indole has a difference (Δ) of 6% after 30 mins, 18% after 60 mins, and 58% after 3 hours. Addition of the Piperonyl Butoxide in the test composition (MOD40) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Piperonyl Butoxide, drops in fragrance concentration over the 3 hours. Thus, Piperonyl Butoxide acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(oo) Effects of Diphenhydramine HCl on Composition Having Volatile Fragrance Materials



FIG. 48 shows the effect of the substantially non-odorous fragrance fixative Diphenhydramine HCl on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD41). With reference to FIG. 48, indole has a difference (Δ) of 11% after 30 mins, 23% after 60 mins, and 70% after 3 hours. Addition of the Diphenhydramine HCl in the test composition (MOD41) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Diphenhydramine HCl, drops in fragrance concentration over the 3 hours. Thus, Diphenhydramine HCl acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(pp) Effect of Di(Propylene Glycol) Propyl Ether on Composition Having Volatile Fragrance Materials



FIG. 49 shows the effect of the substantially non-odorous fragrance fixative Di(propylene glycol) propyl ether on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD42). With reference to FIG. 49, indole has a difference (A) of 8% after 30 mins, 21% after 60 mins, and 50% after 3 hours. Addition of the Di(propylene glycol) propyl ether in the test composition (MOD42) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Di(propylene glycol) propyl ether, drops in fragrance concentration over the 3 hours. Thus, Di(propylene glycol) propyl ether acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


(qq) Effects of Poly(Melamine-Co-Formaldehyde) Methylated on Composition Having a Volatile Fragrance Materials



FIG. 50 shows the effect of the substantially non-odorous fragrance fixative Poly(melamine-co-formaldehyde) methylated on the evaporation profile for a representative component (i.e., indole) of the test composition (MOD43). With reference to FIG. 50, indole has a difference (Δ) of 9% after 30 mins, 20% after 60 mins, and 62% after 3 hours. Addition of the Poly(melamine-co-formaldehyde) methylated in the test composition (MOD43) maintains the concentration of the volatile fragrance material indole from 0 hour up to 3 hours whilst the control composition (REF), in the absence of Poly(melamine-co-formaldehyde) methylated, drops in fragrance concentration over the 3 hours. Thus, Poly(melamine-co-formaldehyde) methylated acts to maintain the continued evaporation of the volatile fragrance material over time. Similar results are observed for the other volatile fragrance materials in the mixture (data not shown).


Example 7
Analytical Headspace Test Results

Using the analytical headspace Test Method 4, it is possible to demonstrate the character retention over time of a perfume mixture of a fragrance composition of the present invention vs. a control. Compositions disclosed in Table 19(a) are added to sealed vials in accordance with the procotol described in the Method Section, and the fragrance profile in the headspace are measured at specific time points through the use of headspace gas chromatography.


(a) Effects of the Substantially Non-Odorous Fragrance Fixatives on Character Retention of Compositions Having Reduced Levels of Low Volatile Fragrance Materials (Between 10 to 30 wt % Relative to the Total Weight of the Fragrance Component) Vs. Compositions Having Traditional Levels of Low Volatile Fragrance Materials (Greater than 30 wt % Relative to the Total Weight of the Fragrance Component)


The test demonstrates the character retention over time of a fragrance composition. The results show the effect of the substantially non-odorous fragrance fixative and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A1 on fragrance profile longevity versus control Compositions C1 in the absence of the substantially non-odorous fixative. Alternatively, results show the effect of the substantially non-odorous fragrance fixative and reduced levels of low volatile fragrance materials for any one of the inventive Compositions A1 on fragrance profile longevity versus traditional Compositions B1 in the presence of the substantially non-odorous fragrance fixative. Fragrance profile fidelity, particularly characters attributable to the volatile fragrance materials are maintained for up to at least 1 hour in the presence of the substantially non-odorous fragrance fixative whilst it drops in the absence of the substantially non-odorous fragrance fixative.


It should be understood that every maximum numerical limitation given throughout this specification includes every lower numerical limitation, as if such lower numerical limitations were expressly written herein. Every minimum numerical limitation given throughout this specification will include every higher numerical limitation, as if such higher numerical limitations were expressly written herein. Every numerical range given throughout this specification will include every narrower numerical range that falls within such broader numerical range, as if such narrower numerical.


The dimensions and values disclosed herein are not to be understood as being strictly limited to the exact numerical values recited. Instead, unless otherwise specified, each such dimension is intended to mean both the recited value and a functionally equivalent range surrounding that value. For example, a dimension disclosed as “40 mm” is intended to mean “about 40 mm.”


Every document cited herein, including any cross referenced or related patent or application and any patent application or patent to which this application claims priority or benefit thereof, is hereby incorporated herein by reference in its entirety unless expressly excluded or otherwise limited. The citation of any document is not an admission that it is prior art with respect to any invention disclosed or claimed herein or that it alone, or in any combination with any other reference or references, teaches, suggests or discloses any such invention. Further, to the extent that any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this document shall govern.


While particular embodiments of the present invention have been illustrated and described, it would be obvious to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. It is therefore intended to cover in the appended claims all such changes and modifications that are within the scope of this invention.

Claims
  • 1. A composition comprising: (i) a fragrance component present in an amount of from about 0.04 wt % to about 30 wt %, relative to the total weight of the composition; and(ii) at least one substantially non-odorous fragrance fixative from the group consisting of the materials in Table 1, wherein the substantially non-odorous fragrance fixative is present in the amount of from about 0.1 wt % to about 20 wt %, relative to the total weight of the composition.
  • 2. The composition according to claim 1, wherein: (i) the fragrance component is present from about 0.04 wt % to about 30 wt %, relative to the total weight of composition, and wherein the fragrance component comprises: (a) at least one low volatile fragrance material having a vapor pressure less than 0.001 Torr (0.000133 kPa) at 25° C.; and(b) the low volatile fragrance material is present in an amount of less than about 30 wt %, relative to the total weight of the fragrance component; and(ii) at least one substantially non-odorous fragrance fixative present in the amount of from about 0.1 wt % to about 20 wt %, relative to the total weight of the composition.
  • 3. The composition according to claim 2, wherein the low volatile fragrance material is present in an amount of from about 10 wt % to about 30 wt %, relative to the total weight of the fragrance component.
  • 4. The composition according to claim 2, wherein the low volatile fragrance material is selected from at least 1 material, or at least 2 materials, or at least 3 materials from the group of Low Volatile Fragrance Materials 1-111, IUPAC Names, of Table 2 and mixtures thereof.
  • 5. The composition according to claim 4, wherein the low volatile fragrance material is selected from the group of Table 2 Low Volatile Fragrance Materials 1, 4-6, 8, 12-16, 18, 22-28, 31, 34-37, 41, 45, 47, 52-55, 57, 60, 61, 63, 65, 68, 69-73, 75, 78, 80, 83-84, 89, 94, 99, 102, 104, 106-108, and mixtures thereof.
  • 6. The composition according to claim 2, wherein: (i) the fragrance component further comprising one or more volatile fragrance materials, wherein: (c) the volatile fragrance material has a vapor pressure greater than or equal to 0.001 Torr (0.000133 kPa) at 25° C.;(d) the volatile fragrance material is present in an amount of from about 70 wt % to about 99.9 wt %, relative to the total weight of the fragrance component; and(e) mixtures thereof.
  • 7. The composition according to claim 6, wherein the volatile fragrance material is selected from at least 1 material, or at least 3 materials, or at least 5 materials from the group of Volatile Fragrance Materials 1-449, IUPAC Names, of Table 3 and mixtures thereof.
  • 8. The composition according to claim 7, wherein the volatile fragrance material is selected from the group of Table 3 Volatile Fragrance Materials 4, 6, 18, 54, 60, 77, 92, 105, 107, 119, 122, 134, 138, 141, 144, 148, 152, 155, 158, 167, 173, 175, 176, 182, 186, 189, 193, 195, 196, 202, 205, 206, 207, 210, 212, 225, 235, 238, 243, 245, 257, 271, 273, 274, 279-280, 282, 285, 289, 293, 297, 302, 305-306, 314, 315, 318, 354-355, 410, 416, and mixtures thereof.
  • 9. The composition according to claim 6, wherein the volatile fragrance material is selected from the group consisting of: (f) a high volatile fragrance material having a vapor pressure greater than 0.1 Torr (0.0133 kPa) at 25° C., present in an amount of from about 1 wt % to about 30 wt %, relative to the total weight of the fragrance component;(g) a moderate volatile fragrance material having a vapor pressure in the range of 0.1 Torr (0.0133 kPa) to 0.001 Torr (0.000133 kPa) at 25° C., present in an amount of from about 40 wt % to about 80 wt %, relative to the total weight of the fragrance component; and(h) mixtures thereof.
  • 10. The composition according to claim 1, further comprising a volatile solvent present in the amount of from about 10 wt % to about 90 wt %, relative to the total weight of the composition, and wherein the solvent is a branch or unbranched C1 to C10 alkyl, akenyl or alkynyl group having at least one alcohol moiety.
  • 11. The composition according to claim 1, wherein the composition is a fine fragrance composition, preferably in the form of a perfume concentrate, a perfume, a parfum, an eau de toilette, an eau de parfum or a cologne.
  • 12. The composition according to claim 1, wherein the composition is in the form of a body splash or a body spray.
  • 13. The composition according to claim 1, wherein the substantially non-odorous fragrance fixative and fragrance component are present in a weight ratio from about 10:1 to about 1:10.
  • 14. The composition according to claim 1, wherein the substantially non-odorous fragrance fixative is selected from the group consisting of Table 1 substantially non-odorous fragrance fixatives 1-190, 191 and mixtures thereof.
  • 15. A method of modifying or enhancing the odour properties of a substrate, comprising contacting or treating the substrate with a composition according to claim 1.
  • 16. A substantially non-odorous fragrance fixative for fragrance materials, wherein the substantially non-odorous fragrance fixative comprises at least one material selected from the group consisting of the materials in Table 1.
  • 17. A perfuming consumer product or article comprising a composition according to claim 1, wherein the perfuming consumer product is selected from the group consisting of a fabric care product, an air care product or a home care product.
Provisional Applications (1)
Number Date Country
62175439 Jun 2015 US