Claims
- 1. A thermal transfer system, comprising:
a container for receiving a medium; a structure positioned in the container such that the structure segments the container into a plurality of compartments wherein a distal end of the structure is in close proximity to an interior surface of the container to allow formation of a thermal transfer bridge that conducts heat into or out of the medium.
- 2. A thermal transfer system as in claim 1 including:
a heating or cooling device coupled to and provides heating or cooling of the container.
- 3. A thermal transfer system as in claim 1 including:
a heating or cooling device coupled to and provides heating or cooling of the structure.
- 4. A thermal transfer system as in claim 1 including:
a heating or cooling device coupled to and provides heating or cooling of the container and the structure.
- 5. A thermal transfer system as in claim 1 including:
a plurality of structures in the container.
- 6. A thermal transfer system as in claim 1, including:
a removable liner configured to cover at least a portion of the structure.
- 7. A thermal transfer system as in claim 1 wherein:
a volume of the container is in the range from substantially 1 liter to 250 liters.
- 8. A thermal transfer system as in claim 1 wherein:
a volume of the container is in the range from substantially 250 liter to 10,000 liters.
- 9. A thermal transfer system as in claim 1 wherein:
the distal end of the structure contacts at least a portion of the interior surface of the container.
- 10. A thermal transfer system as in claim 1 wherein:
a distance between the distal end of the structure and the interior surface of the container is a non-contacting distance not greater than one inch.
- 11. A thermal transfer system as in claim 1 wherein:
the container includes a jacket defining an interstitial space positioned between the jacket and a wall of the container for receiving a flow of a heat exchange fluid, the jacket further including a plurality of spiral baffles for enhancing thermal exchange between the heat exchange fluid and the container.
- 12. A thermal transfer system as in claim 1 wherein:
a heat exchange fluid flows within the structure.
- 13. A thermal transfer system as in claim 12 wherein:
an interior portion of the structure has baffles.
- 14. A thermal transfer system as in claim 13 wherein:
the structure is configured to maximize an area of a surface of the structure that is in contact with the medium.
- 15. A thermal transfer system as in claim 12 wherein:
a heat exchange extension is at least partially coupled to the structure.
- 16. A thermal transfer system as in claim 1 wherein:
the medium is substantially uniformly heated or cooled.
- 17. A thermal transfer system as in claim 1 wherein:
the medium is heated or cooled in substantially one direction relative to the structure.
- 18. A thermal transfer system as in claim 1 wherein:
the structure is positioned to induce a thermal gradient in the medium such that the thermal gradient is in a predetermined direction.
- 19. A thermal transfer system as in claim 1 wherein:
the medium is heated or cooled in a predetermined direction.
- 20. A thermal transfer system as in claim 1 wherein:
the medium is heated or cooled such that the thermal gradient is in a predetermined direction.
- 21. A thermal transfer system as in claim 1 wherein:
the medium is heated or cooled at a predetermined rate.
- 22. A thermal transfer system as in claim 1 wherein:
the medium is heated or cooled such that the thermal gradient is in a predetermined direction and the heating or cooling occurs at a predetermined rate.
- 23. A thermal transfer system as in claim 1 wherein:
the medium is a biopharmaceutical product.
- 24. A thermal transfer system as in claim 1 wherein:
the container has a nonporous bottom.
- 25. A thermal transfer system as in claim 1 wherein:
the container has nonporous walls.
- 26. A thermal transfer system as in claim 1 wherein:
the container has a top.
- 27. A thermal transfer system as in claim 1 wherein:
the container has a nonporous top.
- 28. A thermal transfer system as in claim 1 including:
a distal portion of the structure configured to improve thermal transport of the thermal transfer bridge.
- 29. A thermal transfer system as in claim 1 wherein:
the medium includes protiens.
- 30. A thermal transfer system comprising:
a container for receiving a medium; a structure positioned in the container, a heat exchange member at least partially coupled to the structure and extending into the container wherein a distal end of the heat exchange member is placed in close proximity to an interior surface of the container to allow the formation of a thermal transfer bridge that conducts heat into and out of the medium.
- 31. A thermal transfer system as in claim 30 wherein:
a heating or cooling device is coupled to and provides heating or cooling of the container.
- 32. A thermal transfer system as in claim 30 wherein:
a heating or cooling device is coupled to and provides heating or cooling of the structure positioned inside the container.
- 33. A thermal transfer system as in claim 30 wherein:
a heating or cooling device is coupled to and provides heating or cooling of the structure and the container.
- 34. A thermal transfer system as in claim 30 wherein:
there is a plurality of heat exchange members.
- 35. A thermal transfer system as in claim 30, further comprising:
a removable liner configured to cover at least a portion of the heat exchange member.
- 36. A thermal transfer system as in claim 30 wherein:
a volume of the container is in the range from substantially 1 liter to 250 liters.
- 37. A thermal transfer system as in claim 30 wherein:
a volume of the container is in the range from substantially 250 liter to 10,000 liters.
- 38. A thermal transfer system as in claim 30 wherein:
the container includes a jacket defining an interstitial space positioned between the jacket and a wall of the container for receiving a flow of a heat exchange fluid, the jacket further including a plurality of spiral baffles for enhancing thermal exchange between the heat exchange fluid and the container.
- 39. A thermal transfer system as in claim 30 wherein:
a heat exchange fluid flows within the structure.
- 40. A thermal transfer system as in claim 30 wherein:
the heat exchange fluid flows into the structure through an interior passage in the structure.
- 41. A thermal transfer system as in claim 30 wherein:
the heat exchange fluid flows out of the structure through an outer passage in the structure wherein one portion of the outer passage comprises an outer wall of the structure.
- 42. A thermal transfer system as in claim 30 wherein:
a heat exchange fluid flows within the heat exchange member.
- 43. A thermal transfer system as in claim 39 wherein:
an interior portion of the structure has baffles.
- 44. A thermal transfer system as in claim 42 wherein:
an interior portion of the heat exchange member has baffles.
- 45. A thermal transfer system as in claim 39 wherein:
an interior portion of the portion of the structure extending into the container has baffles.
- 46. A thermal transfer system as in claim 39 wherein:
the heat exchange fluid flows into the heat exchange member from the structure.
- 47. A thermal transfer system as in claim 30 wherein:
a heat exchange fluid flows into the heat exchange member from a heat exchange supply line.
- 48. A thermal transfer system as in claim 38 wherein:
the heat exchange fluid flows does not flow through the distal end of the heat exchange member.
- 49. A thermal transfer system as in claim 30 wherein:
a distance between the distal end of the heat exchange member and the interior surface of the container is a non-contacting distance not greater than one inch.
- 50. A thermal transfer system as in claim 30 wherein:
the medium is substantially uniformly heated or cooled.
- 51. A thermal transfer system as in claim 30 wherein:
the medium is heated or cooled in substantially one direction relative to the structure.
- 52. A thermal transfer system as in claim 30 wherein:
the medium is heated or cooled at a predetermined rate.
- 53. A thermal transfer system as in claim 30 wherein:
the medium is heated or cooled such that the thermal gradient is in a predetermined direction and the heating or cooling occurs at a predetermined rate.
- 54. A thermal transfer system as in claim 30 wherein:
the medium is a biopharmaceutical product.
- 55. A thermal transfer system as in claim 30 wherein:
the medium includes protiens.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a continuation of U.S. patent application Ser. No. 09/895,777 filed on Jul. 17, 1997, which claims the benefit of Provisional Application Serial No. 60/1037,283, filed Feb. 4, 1997. The present application is related to U.S. patent application Ser. No. 08/895,836, filed Jul. 17, 1997. All applications being hereby incorporated by reference as if repeated herein in its entirety, including the drawings.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60037283 |
Feb 1997 |
US |
Continuations (2)
|
Number |
Date |
Country |
Parent |
08895777 |
Jul 1997 |
US |
Child |
09881909 |
Jun 2001 |
US |
Parent |
08895936 |
Jul 1997 |
US |
Child |
09881909 |
Jun 2001 |
US |