FTLV AS A SMALL LABORATORY MODEL OF HIV

Information

  • Research Project
  • 3488952
  • ApplicationId
    3488952
  • Core Project Number
    R43AI027605
  • Full Project Number
    1R43AI027605-01
  • Serial Number
    27605
  • FOA Number
  • Sub Project Id
  • Project Start Date
    2/1/1989 - 36 years ago
  • Project End Date
    7/31/1989 - 35 years ago
  • Program Officer Name
  • Budget Start Date
    2/1/1989 - 36 years ago
  • Budget End Date
    7/31/1989 - 35 years ago
  • Fiscal Year
    1989
  • Support Year
    1
  • Suffix
  • Award Notice Date
    1/31/1989 - 36 years ago
Organizations

FTLV AS A SMALL LABORATORY MODEL OF HIV

The long term objectives of this proposal are to develop methodologies and a knowledge base that will enhance the utilization of Feline T-cell lymphotropic lentivirus (FTLV) as a small laboratory animal model of HIV. In Phase I of this proposal, we will develop an FTLV antigen test which will augment our existing antibody tests and provide veterinarians and research scientists with diagnostic tools to monitor FTLV infection. We also propose to begin nucleic acid sequence analysis of FTLV to obtain a better understanding of the genomic organization of this virus and compare these results with the known sequence of HIV and other lentivirus. The FTLV model possesses advantages for the development of drugs to block lentivirus replication and to evaluate a particular approach in the development of lentivirus vaccines.

IC Name
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
  • Activity
    R43
  • Administering IC
    AI
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    856
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    ARR
  • Study Section Name
  • Organization Name
    IDEXX LABORATORIES, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    WESTBROOK
  • Organization State
    ME
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    04092
  • Organization District
    UNITED STATES