Claims
- 1. A sulfoxide derivative having the formula (V): ##STR11## wherein each of R.sup.5 and R.sup.6 independently is hydrogen, halogen, an alkyl group having 1 to 6 carbon atoms, or an alkoxy group having 1 to 6 carbon atoms, R.sup.7 is hydrogen, an alkyl group having 1 to 6 carbon atoms, or an alkoxy group having 1 to 6 carbon atoms, Y is CH, and Z is a 2-aminophenyl group having the formula (VI): ##STR12## ##STR13## wherein each of R.sup.8 and R.sup.9 independently is hydrogen, an alkyl group having 1 to 6 carbon atoms which may be substituted with hydroxyl, phenyl, a phenylalkyl group containing an alkyl chain of 1 to 4 carbon atoms, and a cycloalkyl group having 5 to 8 carbon atoms, R.sup.8 and R.sup.9 may form together with the adjacent nitrogen atom a heterocyclic group having 4 to 6 carbon atoms, and each of R.sup.10, R.sup.10a and R.sup.10b independently is hydrogen, halogen, hydroxyl, an alkoxy group having 1 to 6 carbon atoms which may be substituted with fluorine, an alkyl group having 1 to 6 carbon atoms, or trifluoromethyl.
- 2. The sulfoxide derivative as claimed in claim 1, wherein each of R.sup.5, R.sup.6 and R.sup.7 independently is hydrogen or methyl.
- 3. The sulfoxide derivative as claimed in claim 1, wherein each of R.sup.8 and R.sup.9 independently is an alkyl group having 1 to 6 carbon atoms or a cycloalkyl having 5 to 8 carbon atoms.
- 4. The sulfoxide derivative as claimed in claim 1, wherein each of R.sup.8 and R.sup.9 independently is methyl, ethyl, propyl, isobutyl, cyclopentyl or cyclohexyl.
- 5. The sulfoxide derivative as claimed in claim 1, wherein said derivative is:
- [2-(2-pyridylmethylsulfinyl)quinoxaline;
- 3-methyl-2-(2-pyridylmethylsulfinyl)quinoxaline;
- 2-[2-(4-methoxypyridyl)methylsulfinyl]-3-methylquinoxaline;
- 3-methyl-2-[2-(3-methylpyridyl)methylsulfinyl]-quinoxaline;
- 6,7-dimethyl-2-(2-pyridylmethylsulfinyl)quinoxaline;
- 2-methyl-3-(2-pyridylmethylsulfinyl)pyrido[2,3-b]-pyrazine;]
- 2-(2-dimethylaminobenzylsulfinyl)quinoxaline;
- 2-(2-dimethylaminobenzylsulfinyl)-3-methylquinoxaline;
- 2-(2-dimethylaminobenzylsulfinyl)-3,6,7-trimethyl-quinoxaline;
- 2-(2-dimethylamino-3-methylbenzylsulfinyl)-3-methyl-quinoxaline;
- 2-(2-dimethylamino-5-methylbenzylsulfinyl)-3-methyl-quinoxaline;
- 2-(2-dimethylamino-5-methoxybenzylsulfinyl)-3-methylquinoxaline; or
- 2-(2-diethylaminobenzylsulfinyl)quinoxaline.
- 6. A sulfoxide derivative having the formula (V): ##STR14## wherein each of R.sup.5 and R.sup.6 independently is hydrogen, halogen, an alkyl group having 1 to 6 carbon atoms, or an alkoxy group having 1 to 6 carbon atoms, R.sup.7 is hydrogen, an alkyl group having 1 to 6 carbon atoms, or an alkoxy group having 1 to 6 carbon atoms, Y is CH and Z is 2-pyridyl which may be substituted with an alkoxy group having 1 to 6 carbon atoms, or an alkyl group having 1 to 6 carbon atoms.
- 7. The sulfoxide derivative as claimed in claim 6, wherein each of R.sup.5, R.sup.6 and R.sup.7 independently is hydrogen or methyl.
- 8. The sulfoxide derivative as claimed in claim 6, wherein said derivative is:
- 2-(2-pyridylmethylsulfinyl)quinoxaline;
- 3-methyl-2-(2-pyridylmethylsulfinyl)quinoxaline;
- 2-[2-(4-methoxypyridyl)methylsulfinyl]-3-methyl-quinoxaline;
- 3-methyl-2-[2-(3-methylpyridyl)methylsulfinyl]-quinoxaline;
- 6,7-dimethyl-2-(2-pyridylmethylsulfinyl)quinoxaline.
Priority Claims (2)
Number |
Date |
Country |
Kind |
61-3017 |
Jan 1986 |
JPX |
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61-16169 |
Jan 1986 |
JPX |
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Parent Case Info
This is a divisional application of Ser. No. 07/198,086, filed May 24, 1988 now U.S. Pat. No. 4,933,458, which is a continuation-in-part application of Ser. No. 07/002,367, filed Jan. 12, 1987, now abandoned.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4933342 |
Takahashi et al. |
Jun 1990 |
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4933458 |
Okabe et al. |
Jun 1990 |
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Non-Patent Literature Citations (1)
Entry |
Ota et al., Chemical Abstracts, vol. 108, No. 186590 (1988), (Abstract for JP 62/209062, Sep. 14, 1987). |
Divisions (1)
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Number |
Date |
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Parent |
198086 |
May 1988 |
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Continuations (1)
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Number |
Date |
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Parent |
2367 |
Jan 1987 |
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